2,4-Dinitrophenylhydrazine (BioDeep_00000008577)
Secondary id: BioDeep_00001871901
human metabolite blood metabolite
代谢物信息卡片
2,4-Dinitro-3,5,6-trideuterophenylhydrazine
化学式: C6H6N4O4 (198.0389036)
中文名称: 2,4-二硝基苯肼
谱图信息:
最多检出来源 Homo sapiens(blood) 87.5%
分子结构信息
SMILES: C1=CC(=C(C=C1[N+](=O)[O-])[N+](=O)[O-])NN
InChI: InChI=1S/C6H6N4O4/c7-8-5-2-1-4(9(11)12)3-6(5)10(13)14/h1-3,8H,7H2
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:66932
- KEGG: C11283
- PubChem: 3772977
- HMDB: HMDB0245463
- Metlin: METLIN68962
- ChEMBL: CHEMBL352799
- Wikipedia: 2,4-Dinitrophenylhydrazine
- chemspider: 3001507
- CAS: 119-26-6
- PMhub: MS000022208
- PubChem: 13460
- NIKKAJI: J2.913K
- RefMet: 2,4-Dinitrophenylhydrazine
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Si-Yu Wang, Hui Liu, Jin-Hao Zhu, Shan-Shan Zhou, Jin-Di Xu, Jing Zhou, Qian Mao, Ming Kong, Song-Lin Li, He Zhu. 2,4-dinitrophenylhydrazine capturing combined with mass defect filtering strategy to identify aliphatic aldehydes in biological samples.
Journal of chromatography. A.
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The Journal of biological chemistry.
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Evidence-based complementary and alternative medicine : eCAM.
2011; 2011(?):. doi:
10.1155/2011/546560. [PMID: 20953434] - Guozheng Qin, Jia Liu, Baohua Cao, Boqiang Li, Shiping Tian. Hydrogen peroxide acts on sensitive mitochondrial proteins to induce death of a fungal pathogen revealed by proteomic analysis.
PloS one.
2011; 6(7):e21945. doi:
10.1371/journal.pone.0021945. [PMID: 21755012] - Luciane Conceição Silva Bastos, Pedro Afonso de Paula Pereira. Influence of heating time and metal ions on the amount of free fatty acids and formation rates of selected carbonyl compounds during the thermal oxidation of canola oil.
Journal of agricultural and food chemistry.
2010 Dec; 58(24):12777-83. doi:
10.1021/jf1028575. [PMID: 21105653] - Tillie L Hackett, Marco Scarci, Lu Zheng, Wan Tan, Tom Treasure, Jane A Warner. Oxidative modification of albumin in the parenchymal lung tissue of current smokers with chronic obstructive pulmonary disease.
Respiratory research.
2010 Dec; 11(?):180. doi:
10.1186/1465-9921-11-180. [PMID: 21176186] - Mehar Darukhshan Kalim, Dipto Bhattacharyya, Anindita Banerjee, Sharmila Chattopadhyay. Oxidative DNA damage preventive activity and antioxidant potential of plants used in Unani system of medicine.
BMC complementary and alternative medicine.
2010 Dec; 10(?):77. doi:
10.1186/1472-6882-10-77. [PMID: 21159207] - Vasundhara Kain, Sandeep Kumar, Amrutesh S Puranik, Sandhya L Sitasawad. Azelnidipine protects myocardium in hyperglycemia-induced cardiac damage.
Cardiovascular diabetology.
2010 Dec; 9(?):82. doi:
10.1186/1475-2840-9-82. [PMID: 21118576] - Petronela Zižková, Jana Viskupičová, L'ubica Horáková. Pycnogenol and Ginkgo biloba extract: effect on peroxynitrite-oxidized sarcoplasmic reticulum Ca-ATPase.
Interdisciplinary toxicology.
2010 Dec; 3(4):132-6. doi:
10.2478/v10102-010-0053-8. [PMID: 21331179] - Hiroya Sato, Takeyuki Takahashi, Kazumi Sumitani, Hirokatsu Takatsu, Shiro Urano. Glucocorticoid Generates ROS to Induce Oxidative Injury in the Hippocampus, Leading to Impairment of Cognitive Function of Rats.
Journal of clinical biochemistry and nutrition.
2010 Nov; 47(3):224-32. doi:
10.3164/jcbn.10-58. [PMID: 21103031] - Fars Alanazi. Pravastatin provides antioxidant activity and protection of erythrocytes loaded Primaquine.
International journal of medical sciences.
2010 Oct; 7(6):358-65. doi:
10.7150/ijms.7.358. [PMID: 21060723] - Qiang Dong, Kai Yang, Stephanie M Wong, Peter J O'Brien. Hepatocyte or serum albumin protein carbonylation by oxidized fructose metabolites: Glyceraldehyde or glycolaldehyde as endogenous toxins?.
Chemico-biological interactions.
2010 Oct; 188(1):31-7. doi:
10.1016/j.cbi.2010.06.006. [PMID: 20561512] - Gustavo Scola, Danusa Conte, Patrícia Wilmsen Dalla-Santa Spada, Caroline Dani, Regina Vanderlinde, Claudia Funchal, Mirian Salvador. Flavan-3-ol compounds from wine wastes with in vitro and in vivo antioxidant activity.
Nutrients.
2010 10; 2(10):1048-59. doi:
10.3390/nu2101048. [PMID: 22253995] - Chahid Benammar, Aziz Hichami, Akadiri Yessoufou, Anne-Marie Simonin, Meriem Belarbi, Hocine Allali, Naim A Khan. Zizyphus lotus L. (Desf.) modulates antioxidant activity and human T-cell proliferation.
BMC complementary and alternative medicine.
2010 Sep; 10(?):54. doi:
10.1186/1472-6882-10-54. [PMID: 20868496] - Khedidja Mekki, Warda Taleb, Nassima Bouzidi, Abbou Kaddous, Malika Bouchenak. Effect of hemodialysis and peritoneal dialysis on redox status in chronic renal failure patients: a comparative study.
Lipids in health and disease.
2010 Sep; 9(?):93. doi:
10.1186/1476-511x-9-93. [PMID: 20815897] - Mbang A Owolabi, Moyosola M Abass, Promise M Emeka, Smith I Jaja, Martin Nnoli, Benjamin O S Dosa. Biochemical and histologic changes in rats after prolonged administration of the crude aqueous extract of the leaves of Vitex grandifolia.
Pharmacognosy research.
2010 Sep; 2(5):273-8. doi:
10.4103/0974-8490.72322. [PMID: 21589750] - V Suseela, V K Gopalakrishnan, Sumam Varghese. In vitro Antioxidant Studies of Fruits of Artemisia nilagirica (Clarke) Pamp.
Indian journal of pharmaceutical sciences.
2010 Sep; 72(5):644-9. doi:
10.4103/0250-474x.78538. [PMID: 21695001] - Anke Steppuhn, Emmanuel Gaquerel, Ian T Baldwin. The two alpha-dox genes of Nicotiana attenuata: overlapping but distinct functions in development and stress responses.
BMC plant biology.
2010 Aug; 10(?):171. doi:
10.1186/1471-2229-10-171. [PMID: 20701756] - Megha Saraswat, Palla Suryanarayana, Paduru Yadagiri Reddy, Madhoosudan A Patil, Nagalla Balakrishna, Geereddy Bhanuprakash Reddy. Antiglycating potential of Zingiber officinalis and delay of diabetic cataract in rats.
Molecular vision.
2010 Aug; 16(?):1525-37. doi:
. [PMID: 20806076] - Eduardo Antonio Ferreira, Eliana Fortes Gris, Karina Bettega Felipe, João Francisco Gomes Correia, Eduardo Cargnin-Ferreira, Danilo Wilhelm Filho, Rozangela Curi Pedrosa. Potent hepatoprotective effect in CCl(4)-induced hepatic injury in mice of phloroacetophenone from Myrcia multiflora.
The Libyan journal of medicine.
2010 Jun; 5(?):. doi:
10.3402/ljm.v5i0.4891. [PMID: 21483585] - Juan Huang, Yanli Feng, Jiamo Fu, Guoying Sheng. A method of detecting carbonyl compounds in tree leaves in China.
Environmental science and pollution research international.
2010 Jun; 17(5):1129-36. doi:
10.1007/s11356-009-0277-3. [PMID: 20016999] - Joy G Mohanty, Surya Bhamidipaty, Michele K Evans, Joseph M Rifkind. A fluorimetric semi-microplate format assay of protein carbonyls in blood plasma.
Analytical biochemistry.
2010 May; 400(2):289-94. doi:
10.1016/j.ab.2010.01.032. [PMID: 20122892] - Lee R Hagey, Nicolas Vidal, Alan F Hofmann, Matthew D Krasowski. Evolutionary diversity of bile salts in reptiles and mammals, including analysis of ancient human and extinct giant ground sloth coprolites.
BMC evolutionary biology.
2010 May; 10(?):133. doi:
10.1186/1471-2148-10-133. [PMID: 20444292] - Pinar Atukeren, Seval Aydin, Ezel Uslu, M Koray Gumustas, Ufuk Cakatay. Redox homeostasis of albumin in relation to alpha-lipoic acid and dihydrolipoic acid.
Oxidative medicine and cellular longevity.
2010 May; 3(3):206-13. doi:
10.4161/oxim.3.3.11786. [PMID: 20716945] - Graziano Colombo, Giancarlo Aldini, Marica Orioli, Daniela Giustarini, Rosalba Gornati, Ranieri Rossi, Roberto Colombo, Marina Carini, Aldo Milzani, Isabella Dalle-Donne. Water-Soluble alpha,beta-unsaturated aldehydes of cigarette smoke induce carbonylation of human serum albumin.
Antioxidants & redox signaling.
2010 Mar; 12(3):349-64. doi:
10.1089/ars.2009.2806. [PMID: 19686037] - Lina Yin, Jun'ichi Mano, Shiwen Wang, Wataru Tsuji, Kiyoshi Tanaka. The involvement of lipid peroxide-derived aldehydes in aluminum toxicity of tobacco roots.
Plant physiology.
2010 Mar; 152(3):1406-17. doi:
10.1104/pp.109.151449. [PMID: 20023145] - Clara Eugenia Baños, Manuel Silva. Liquid chromatography-tandem mass spectrometry for the determination of low-molecular mass aldehydes in human urine.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2010 Mar; 878(7-8):653-8. doi:
10.1016/j.jchromb.2010.01.024. [PMID: 20149765] - Mahbubeh Setorki, Sedighe Asgary, Akram Eidi, Ali Haeri Rohani, Majid Khazaei. Acute effects of vinegar intake on some biochemical risk factors of atherosclerosis in hypercholesterolemic rabbits.
Lipids in health and disease.
2010 Jan; 9(?):10. doi:
10.1186/1476-511x-9-10. [PMID: 20109192] - Amanda Fortes Francisco, Paula Melo de Abreu Vieira, Jerusa Marilda Arantes, Maisa Silva, Maria Lúcia Pedrosa, Silvana Maria Elói-Santos, Olindo Assis Martins-Filho, Andréa Teixeira-Carvalho, Márcio Sobreira Silva Araújo, Washington Luiz Tafuri, Cláudia Martins Carneiro. Increase of reactive oxygen species by desferrioxamine during experimental Chagas' disease.
Redox report : communications in free radical research.
2010; 15(4):185-90. doi:
10.1179/174329210x12650506623528. [PMID: 20663295] - Manuel A Matamoros, Jorge Loscos, Karl-Josef Dietz, Pedro M Aparicio-Tejo, Manuel Becana. Function of antioxidant enzymes and metabolites during maturation of pea fruits.
Journal of experimental botany.
2010; 61(1):87-97. doi:
10.1093/jxb/erp285. [PMID: 19822534] - Olga Krystofova, Libuse Trnkova, Vojtech Adam, Josef Zehnalek, Jaromir Hubalek, Petr Babula, Rene Kizek. Electrochemical microsensors for the detection of cadmium(II) and lead(II) ions in plants.
Sensors (Basel, Switzerland).
2010; 10(6):5308-28. doi:
10.3390/s100605308. [PMID: 22219663] - Yong-Jin Chen, Fei Huang, Min Zhang, Hai-Yan Shang. Psychological stress alters ultrastructure and energy metabolism of masticatory muscle in rats.
Journal of biomedicine & biotechnology.
2010; 2010(?):302693. doi:
10.1155/2010/302693. [PMID: 21052548] - H Ibrahim Varan, Belda Dursun, Evrim Dursun, Tomris Ozben, Gultekin Suleymanlar. Acute effects of hemodialysis on oxidative stress parameters in chronic uremic patients: comparison of two dialysis membranes.
International journal of nephrology and renovascular disease.
2010; 3(?):39-45. doi:
10.2147/ijnrd.s6598. [PMID: 21694927] - Paula I Moreira, Lawrence M Sayre, Xiongwei Zhu, Akihiko Nunomura, Mark A Smith, George Perry. Detection and localization of markers of oxidative stress by in situ methods: application in the study of Alzheimer disease.
Methods in molecular biology (Clifton, N.J.).
2010; 610(?):419-34. doi:
10.1007/978-1-60327-029-8_25. [PMID: 20013193] - Tural Galbinur, Alexey Obolensky, Eduard Berenshtein, Vladimir Vinokur, Itay Chowers, Mordechai Chevion, Eyal Banin. Effect of para-aminobenzoic acid on the course of retinal degeneration in the rd10 mouse.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics.
2009 Dec; 25(6):475-82. doi:
10.1089/jop.2009.0020. [PMID: 20028256] - Mahbubeh Setorki, Sedighe Asgary, Akram Eidi, Ali Haeri Rohani, Nafiseh Esmaeil. Effects of apple juice on risk factors of lipid profile, inflammation and coagulation, endothelial markers and atherosclerotic lesions in high cholesterolemic rabbits.
Lipids in health and disease.
2009 Oct; 8(?):39. doi:
10.1186/1476-511x-8-39. [PMID: 19804641] - Jennifer Dorts, Frédéric Silvestre, Huynh Thi Tu, Anne-Eric Tyberghein, Nguyen Thanh Phuong, Patrick Kestemont. Oxidative stress, protein carbonylation and heat shock proteins in the black tiger shrimp, Penaeus monodon, following exposure to endosulfan and deltamethrin.
Environmental toxicology and pharmacology.
2009 Sep; 28(2):302-10. doi:
10.1016/j.etap.2009.05.006. [PMID: 21784020]