DL-Dithiothreitol (BioDeep_00000837572)
Main id: BioDeep_00000001728
代谢物信息卡片
(2S,3S)-1,4-Dimercaptobutane-2,3-diol
化学式: C4H10O2S2 (154.01222)
中文名称: DL-二硫苏糖醇(DTT), 二硫代苏糖醇, L-1,4-二硫代苏糖醇
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(C(C(CS)O)O)S
InChI: InChI=1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m0/s1
描述信息
COVID info from COVID-19 Disease Map
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
同义名列表
数据库引用编号
19 个数据库交叉引用编号
- ChEBI: CHEBI:42170
- ChEBI: CHEBI:42106
- KEGG: C00265
- PubChem: 446094
- PubChem: 439196
- DrugBank: DB02184
- DrugBank: DB04447
- ChEMBL: CHEMBL1232392
- ChEMBL: CHEMBL406270
- MeSH: Dithiothreitol
- CAS: 35454-97-8
- CAS: 27565-41-9
- CAS: 3483-12-3
- CAS: 16096-97-2
- ChEBI: CHEBI:18320
- PubChem: 3563
- PDB-CCD: DTT
- NIKKAJI: J388.818E
- NIKKAJI: J64.633D
分类词条
相关代谢途径
Reactome(0)
BioCyc(47)
- alkylnitronates degradation
- allantoin degradation to ureidoglycolate II (ammonia producing)
- allantoin degradation to glyoxylate III
- superpathway of demethylmenaquinol-8 biosynthesis I
- superpathway of N-acetylneuraminate degradation
- superpathway of hexitol degradation (bacteria)
- 2-carboxy-1,4-naphthoquinol biosynthesis
- superpathway of menaquinol-8 biosynthesis I
- superpathway of chorismate metabolism
- hordatine biosynthesis
- pyrimidine deoxyribonucleotides de novo biosynthesis III
- urea cycle
- superpathway of L-citrulline metabolism
- L-citrulline biosynthesis
- superpathway of pentose and pentitol degradation
- superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass
- stachyose biosynthesis
- streptomycin biosynthesis
- superpathway of CMP-sialic acids biosynthesis
- superpathway of carotenoid biosynthesis in plants
- superpathway of L-lysine degradation
- L-lysine fermentation to acetate and butanoate
- superpathway of glycolysis and the Entner-Doudoroff pathway
- photosynthetic 3-hydroxybutanoate biosynthesis (engineered)
- gluconeogenesis I
- glycolysis II (from fructose 6-phosphate)
- glycolysis I (from glucose 6-phosphate)
- L-homomethionine biosynthesis
- allantoin degradation IV (anaerobic)
- sanguinarine and macarpine biosynthesis
- CMP-N-acetylneuraminate biosynthesis I (eukaryotes)
- pyrimidine deoxyribonucleotides de novo biosynthesis I
- patchoulol biosynthesis
- norspermidine biosynthesis
- superpathway of polyamine biosynthesis III
- GDP-mannose biosynthesis
- superpathway of GDP-mannose-derived O-antigen building blocks biosynthesis
- superpathway of penicillin, cephalosporin and cephamycin biosynthesis
- deacetylcephalosporin C biosynthesis
- isopenicillin N biosynthesis
- puromycin biosynthesis
- L-threonine degradation II
- ubiquinol-8 biosynthesis (prokaryotic)
- L-ascorbate biosynthesis IV
- superpathway of ubiquinol-8 biosynthesis (prokaryotic)
- superpathway of L-threonine metabolism
- pinitol biosynthesis II
PlantCyc(5)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Xuemei Zhang, Chao Geng, Yang Fu, Zhen Lv, Zhonglin Wei, Hongda Wang, Shixue Wang. A Facile and Green Approach for the Preparation of Amine-Functionalized Poly(ethylene glycol) by Reducing Poly(ethylene glycol) Azide with Dithiothreitol.
Biomacromolecules.
2024 Mar; 25(3):1972-1977. doi:
10.1021/acs.biomac.3c01370. [PMID: 38359265] - Renata Bufollo Rodrigues, Mariana Maciel de Oliveira, Francielle Pelegrin Garcia, Tânia Ueda-Nakamura, Sueli de Oliveira Silva, Celso Vataru Nakamura. Dithiothreitol reduces oxidative stress and necrosis caused by ultraviolet A radiation in L929 fibroblasts.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.
2024 Feb; ?(?):. doi:
10.1007/s43630-023-00516-z. [PMID: 38305951] - Meng Huang, Meng Li, Ying Zhang, Huan Gong, Yuju Zhou, Danping Zhu, Lingxi Li, Ning Ma, Yan Cui. Novel flavan-3-ol-dithiothreitol conjugates derived from the degradation of grape seed proanthocyanidins and their neuroprotective potential.
Food chemistry.
2023 Mar; 405(Pt A):134825. doi:
10.1016/j.foodchem.2022.134825. [PMID: 36356360] - Song Li, Sheng-Jie Yue, Peng Huang, Tong-Tong Feng, Hong-Yan Zhang, Rui-Lian Yao, Wei Wang, Xue-Hong Zhang, Hong-Bo Hu. Comparative metabolomics and transcriptomics analyses provide insights into the high-yield mechanism of phenazines biosynthesis in Pseudomonas chlororaphis GP72.
Journal of applied microbiology.
2022 Nov; 133(5):2790-2801. doi:
10.1111/jam.15727. [PMID: 35870153] - José Manuel Ugalde, Isabel Aller, Lika Kudrjasova, Romy R Schmidt, Michelle Schlößer, Maria Homagk, Philippe Fuchs, Sophie Lichtenauer, Markus Schwarzländer, Stefanie J Müller-Schüssele, Andreas J Meyer. Endoplasmic reticulum oxidoreductin provides resilience against reductive stress and hypoxic conditions by mediating luminal redox dynamics.
The Plant cell.
2022 09; 34(10):4007-4027. doi:
10.1093/plcell/koac202. [PMID: 35818121] - Ruveyda Kilic Boz, Duygu Aydin, Salli Kocak, Bianka Golba, Rana Sanyal, Amitav Sanyal. Redox-Responsive Hydrogels for Tunable and 'On-Demand' Release of Biomacromolecules.
Bioconjugate chemistry.
2022 05; 33(5):839-847. doi:
10.1021/acs.bioconjchem.2c00094. [PMID: 35446015] - Wenhui Song, Weiyao Zhang, Lizhou Yue, Weiying Lin. Revealing the Effects of Endoplasmic Reticulum Stress on Ferroptosis by Two-Channel Real-Time Imaging of pH and Viscosity.
Analytical chemistry.
2022 05; 94(17):6557-6565. doi:
10.1021/acs.analchem.2c00387. [PMID: 35435658] - Gokul G, Jogender Singh. Dithiothreitol causes toxicity in C. elegans by modulating the methionine-homocysteine cycle.
eLife.
2022 04; 11(?):. doi:
10.7554/elife.76021. [PMID: 35438636] - Karollyny Roger Pereira Lima, Francisco Lucas Pacheco Cavalcante, Stelamaris de Oliveira Paula-Marinho, Isabelle Mary Costa Pereira, Lineker de Sousa Lopes, João Victor Serra Nunes, Ítalo Antônio Cotta Coutinho, Enéas Gomes-Filho, Humberto Henrique de Carvalho. Metabolomic profiles exhibit the influence of endoplasmic reticulum stress on sorghum seedling growth over time.
Plant physiology and biochemistry : PPB.
2022 Jan; 170(?):192-205. doi:
10.1016/j.plaphy.2021.11.041. [PMID: 34902782] - Nunzia Limatola, Jong Tai Chun, Sawsen Cherraben, Jean-Louis Schmitt, Jean-Marie Lehn, Luigia Santella. Effects of Dithiothreitol on Fertilization and Early Development in Sea Urchin.
Cells.
2021 12; 10(12):. doi:
10.3390/cells10123573. [PMID: 34944081] - Ramses Cruz-Valencia, Aldo A Arvizu-Flores, Jesús A Rosas-Rodríguez, Elisa M Valenzuela-Soto. Effect of the drug cyclophosphamide on the activity of porcine kidney betaine aldehyde dehydrogenase.
Molecular and cellular biochemistry.
2021 Mar; 476(3):1467-1475. doi:
10.1007/s11010-020-04010-3. [PMID: 33389495] - Lorenzo Ferroni, Andrea Colpo, Costanza Baldisserotto, Simonetta Pancaldi. In an ancient vascular plant the intermediate relaxing component of NPQ depends on a reduced stroma: Evidence from dithiothreitol treatment.
Journal of photochemistry and photobiology. B, Biology.
2021 Feb; 215(?):112114. doi:
10.1016/j.jphotobiol.2020.112114. [PMID: 33385824] - Tony Tremblay, Donald R Branch, Lionel Loubaki. Daudi cell stroma: An alternative to dithiothreitol to resolve daratumumab interference in pretransfusion testing.
Transfusion.
2020 09; 60(9):2090-2096. doi:
10.1111/trf.15932. [PMID: 32632934] - Andrew T Bender, Benjamin P Sullivan, Lorraine Lillis, Jonathan D Posner. Enzymatic and Chemical-Based Methods to Inactivate Endogenous Blood Ribonucleases for Nucleic Acid Diagnostics.
The Journal of molecular diagnostics : JMD.
2020 08; 22(8):1030-1040. doi:
10.1016/j.jmoldx.2020.04.211. [PMID: 32450280] - Huiying Liu, Feng Xu, Yuqing Gao, Yuanyuan Pang, Cen Xie, Changtao Jiang. An Integrated LC-MS/MS Strategy for Quantifying the Oxidative-Redox Metabolome in Multiple Biological Samples.
Analytical chemistry.
2020 07; 92(13):8810-8818. doi:
10.1021/acs.analchem.0c00242. [PMID: 32510199] - Lucas J McKinnon, Jeremy Fukushima, Joshua K Endow, Kentaro Inoue, Steven M Theg. Membrane Chaperoning of a Thylakoid Protease Whose Structural Stability Is Modified by the Protonmotive Force.
The Plant cell.
2020 05; 32(5):1589-1609. doi:
10.1105/tpc.19.00797. [PMID: 32169961] - Zehui Wei, Peiru Fan, Yajie Jiao, Yang Wang, Yanping Huang, Zhaosheng Liu. Integrated microfluidic chip for on-line proteome analysis with combination of denaturing and rapid digestion of protein.
Analytica chimica acta.
2020 Mar; 1102(?):1-10. doi:
10.1016/j.aca.2020.01.025. [PMID: 32043988] - Gizem Tumer, Thomas Gniadek, Jennifer Baye, Ryan Pena, Paul Warner, Mark Fung, Lynette Beaudin, Heather Dunckley, Manish Gandhi, Birgit Gathof, Susan Hsu, Ellen Klohe, Nalaja Marcus, Roberta Bamert, Shona Sims, Minoko Takanashi, Silvano Wendel, Claudia S Cohn. The effect of serum pretreatment regimens for the detection of HLA class I antibodies in platelet-refractory patients.
Transfusion.
2020 03; 60(3):488-497. doi:
10.1111/trf.15666. [PMID: 31951028] - Cinthia Silva de Queiroz, Isabelle Mary Costa Pereira, Karollyny Roger Pereira Lima, Raissa Souza Caminha Bret, Murilo Siqueira Alves, Enéas Gomes-Filho, Humberto Henrique de Carvalho. Combined NaCl and DTT diminish harmful ER-stress effects in the sorghum seedlings CSF 20 variety.
Plant physiology and biochemistry : PPB.
2020 Feb; 147(?):223-234. doi:
10.1016/j.plaphy.2019.12.013. [PMID: 31874339] - Heather A Walters, Brenda H Welter, William J Sullivan, Lesly A Temesvari. Phosphorylation of eukaryotic initiation factor-2α in response to endoplasmic reticulum and nitrosative stress in the human protozoan parasite, Entamoeba histolytica.
Molecular and biochemical parasitology.
2019 12; 234(?):111223. doi:
10.1016/j.molbiopara.2019.111223. [PMID: 31568804] - Hoon Seok Kim, Ae Ran Choi, Mina Yang, Eun Jee Oh. EDTA Treatment for Overcoming the Prozone Effect and for Predicting C1q Binding in HLA Antibody Testing.
Annals of laboratory medicine.
2019 Nov; 39(6):572-576. doi:
10.3343/alm.2019.39.6.572. [PMID: 31240886] - Haonan Xing, Lin Cheng, Mei Lu, Hui Liu, Lang Lang, Tianzhi Yang, Xiaoyun Zhao, Hui Xu, Li Yang, Pingtian Ding. A biodegradable poly(amido amine) based on the antimicrobial polymer polyhexamethylene biguanide for efficient and safe gene delivery.
Colloids and surfaces. B, Biointerfaces.
2019 Oct; 182(?):110355. doi:
10.1016/j.colsurfb.2019.110355. [PMID: 31306828] - Yasumasa Okazaki, Hiromasa Tanaka, Masaru Hori, Shinya Toyokuni. l-Dehydroascorbic acid recycled by thiols efficiently scavenges non-thermal plasma-induced hydroxyl radicals.
Archives of biochemistry and biophysics.
2019 07; 669(?):87-95. doi:
10.1016/j.abb.2019.05.019. [PMID: 31153952] - Hong Sheng Jiang, Yizhi Zhang, Zhen Wei Lu, Régine Lebrun, Brigitte Gontero, Wei Li. Interaction between Silver Nanoparticles and Two Dehydrogenases: Role of Thiol Groups.
Small (Weinheim an der Bergstrasse, Germany).
2019 07; 15(27):e1900860. doi:
10.1002/smll.201900860. [PMID: 31111667] - Zhenyu Yao, Yanmin Zhang, Lawrence A Potempa, Ibraheem Rajab, Lianxing Ji, Jianmin Lv, Shanhui Liu, Lin Zhang, Haibin Wu. A redox sensitivity-based method to quantify both pentameric and monomeric C-reactive protein in a single assay.
Journal of immunological methods.
2019 07; 470(?):40-45. doi:
10.1016/j.jim.2019.04.009. [PMID: 31034879] - Xing Yu, Tanchun Wang, Meichen Zhu, Liting Zhang, Fengzhi Zhang, Enen Jing, Yongzhe Ren, Zhiqiang Wang, Zeyu Xin, Tongbao Lin. Transcriptome and physiological analyses for revealing genes involved in wheat response to endoplasmic reticulum stress.
BMC plant biology.
2019 May; 19(1):193. doi:
10.1186/s12870-019-1798-7. [PMID: 31072347] - Karen N Chinoca Ziza, Tainá A Paiva, Sabrina R Mota, Marcia Regina Dezan, Luciana Cayres Schmidt, Denise Menezes Brunetta, Gustavo Ricci, Fernando Valadares Basques, Fernando Barroso-Duarte, Vanderson Rocha, Alfredo Mendrone-Junior, Carla Luana Dinardo. A blockage monoclonal antibody protocol as an alternative strategy to avoid anti-CD38 interference in immunohematological testing.
Transfusion.
2019 05; 59(5):1827-1835. doi:
10.1111/trf.15202. [PMID: 30779172] - Soundappan S Mohanraj, Mariyamma Gujjarlapudi, Vadthya Lokya, Nalini Mallikarjuna, Aparna Dutta-Gupta, Kollipara Padmasree. Purification and characterization of Bowman-Birk and Kunitz isoinhibitors from the seeds of Rhynchosia sublobata (Schumach.) Meikle, a wild relative of pigeonpea.
Phytochemistry.
2019 Mar; 159(?):159-171. doi:
10.1016/j.phytochem.2018.12.018. [PMID: 30634078] - R Michael E Parkhouse, Arturo Carpio, Alfredo Campoverde, Patricia Sastre, Glenda Rojas, Leslie J S Harrison, Maria Milagros Cortez. A modified lateral flow assay, using serum, for the rapid identification of human and bovine cysticercosis in the absence of false positives.
Transactions of the Royal Society of Tropical Medicine and Hygiene.
2019 02; 113(2):101-104. doi:
10.1093/trstmh/try116. [PMID: 30383274] - Xueqin Gao, Bingqi Sun, Yifu Guan. Pullulan reduces the non-specific amplification of loop-mediated isothermal amplification (LAMP).
Analytical and bioanalytical chemistry.
2019 Feb; 411(6):1211-1218. doi:
10.1007/s00216-018-1552-2. [PMID: 30617407] - Lorraine N Blagg. Sulfhydryl treatment of serum or plasma for the reduction of IgM antibodies.
Immunohematology.
2018 Dec; 34(4):135-139. doi:
10.21307/immunohematology-2018-021. [PMID: 30624946] - R Serafini, D D Varner, T L Blanchard, S R Teague, K LaCaze, C C Love. Effects of seminal plasma and flash-freezing on DNA structure of stallion epididymal sperm exposed to different potentiators of DNA damage.
Theriogenology.
2018 Sep; 117(?):34-39. doi:
10.1016/j.theriogenology.2018.05.023. [PMID: 29807256] - Tugce Nihal Gevrek, Merve Cosar, Duygu Aydin, Elif Kaga, Mehmet Arslan, Rana Sanyal, Amitav Sanyal. Facile Fabrication of a Modular 'Catch and Release' Hydrogel Interface: Harnessing Thiol-Disulfide Exchange for Reversible Protein Capture and Cell Attachment.
ACS applied materials & interfaces.
2018 May; 10(17):14399-14409. doi:
10.1021/acsami.8b00802. [PMID: 29637775] - J-P Sigle, B Mihm, R Suna, M Bargetzi. Extending shelf life of dithiothreitol-treated panel RBCs to 28 days.
Vox sanguinis.
2018 May; 113(4):397-399. doi:
10.1111/vox.12645. [PMID: 29512161] - Laura Martos, Luis Andrés Ramón, Julia Oto, Álvaro Fernández-Pardo, Santiago Bonanad, Ana Rosa Cid, Andras Gruber, John H Griffin, Francisco España, Silvia Navarro, Pilar Medina. α2-Macroglobulin Is a Significant In Vivo Inhibitor of Activated Protein C and Low APC:α2M Levels Are Associated with Venous Thromboembolism.
Thrombosis and haemostasis.
2018 04; 118(4):630-638. doi:
10.1055/s-0038-1629902. [PMID: 29448296] - J E Araújo, H López-Fernández, M S Diniz, Pedro M Baltazar, Luís Campos Pinheiro, Fernando Calais da Silva, Mylène Carrascal, Paula Videira, H M Santos, J L Capelo. Dithiothreitol-based protein equalization technology to unravel biomarkers for bladder cancer.
Talanta.
2018 Apr; 180(?):36-46. doi:
10.1016/j.talanta.2017.11.063. [PMID: 29332824] - Reza Heidari, Vahid Ghanbarinejad, Hamidreza Mohammadi, Asrin Ahmadi, Athena Esfandiari, Negar Azarpira, Hossein Niknahad. Dithiothreitol supplementation mitigates hepatic and renal injury in bile duct ligated mice: Potential application in the treatment of cholestasis-associated complications.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2018 Mar; 99(?):1022-1032. doi:
10.1016/j.biopha.2018.01.018. [PMID: 29307496] - Ji-Hye Jang, Yun Shang, Hyun Kyung Kang, Sun Young Kim, Beg Hab Kim, Kyoung Hee Nam. Arabidopsis galactinol synthases 1 (AtGOLS1) negatively regulates seed germination.
Plant science : an international journal of experimental plant biology.
2018 Feb; 267(?):94-101. doi:
10.1016/j.plantsci.2017.11.010. [PMID: 29362103] - Asmae Zerrouki, Sanae Ouadghiri, Nadia Benseffaj, Rachid Razine, Malika Essakalli. Reason and Resolution of High Negative Control Beads in Solid-Phase Immunoassay.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation.
2018 Feb; 16(1):38-43. doi:
10.6002/ect.2016.0239. [PMID: 28540842] - V Deneys, C Thiry, A Frelik, C Debry, B Martin, C Doyen. Daratumumab: Therapeutic asset, biological trap!.
Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine.
2018 Feb; 25(1):2-7. doi:
10.1016/j.tracli.2017.12.001. [PMID: 29336950] - Pingping Liang, Juan Canoura, Haixiang Yu, Obtin Alkhamis, Yi Xiao. Dithiothreitol-Regulated Coverage of Oligonucleotide-Modified Gold Nanoparticles To Achieve Optimized Biosensor Performance.
ACS applied materials & interfaces.
2018 Jan; 10(4):4233-4242. doi:
10.1021/acsami.7b16914. [PMID: 29313333] - Emi Ooe, Yoshiki Kuse, Tomohiro Yako, Tetsuya Sogon, Shinsuke Nakamura, Hideaki Hara, Masamitsu Shimazawa. Bilberry extract and anthocyanins suppress unfolded protein response induced by exposure to blue LED light of cells in photoreceptor cell line.
Molecular vision.
2018; 24(?):621-632. doi:
". [PMID: 30294201] - Zoe Gerstle, Rohan Desai, Sarah L Veatch. Giant Plasma Membrane Vesicles: An Experimental Tool for Probing the Effects of Drugs and Other Conditions on Membrane Domain Stability.
Methods in enzymology.
2018; 603(?):129-150. doi:
10.1016/bs.mie.2018.02.007. [PMID: 29673522] - Lihua Tan, Cailan Li, Hanbin Chen, Zhizhun Mo, Jiangtao Zhou, Yuhong Liu, Zhilin Ma, Yuyao Xu, Xiaobo Yang, Jianhui Xie, Ziren Su. Epiberberine, a natural protoberberine alkaloid, inhibits urease of Helicobacter pylori and jack bean: Susceptibility and mechanism.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2017 Dec; 110(?):77-86. doi:
10.1016/j.ejps.2017.02.004. [PMID: 28167234] - Xiaohai Zhang, Nancy L Reinsmoen. Comprehensive assessment for serum treatment for single antigen test for detection of HLA antibodies.
Human immunology.
2017 Nov; 78(11-12):699-703. doi:
10.1016/j.humimm.2017.09.001. [PMID: 28899793] - Dmitriy A Kara, Vera A Borzova, Kira A Markossian, Sergey Yu Kleymenov, Boris I Kurganov. A change in the pathway of dithiothreitol-induced aggregation of bovine serum albumin in the presence of polyamines and arginine.
International journal of biological macromolecules.
2017 Nov; 104(Pt A):889-899. doi:
10.1016/j.ijbiomac.2017.06.092. [PMID: 28652151] - Louis A Altamura, Lisa H Cazares, Susan R Coyne, James G Jaissle, Alyssa M Jespersen, Sundus Ahmed, Leonard P Wasieloski, Jeff Garrison, David A Kulesh, Ernst E Brueggemann, Tara Kenny, Michael D Ward, David E Harbourt, Timothy D Minogue. Inactivation of West Nile virus in serum with heat, ionic detergent, and reducing agent for proteomic applications.
Journal of virological methods.
2017 10; 248(?):1-6. doi:
10.1016/j.jviromet.2017.05.010. [PMID: 28532602] - Kazuyoshi Yamauchi, Yuka Ebihara, Yasushi Kawakami. Redox status of serum apolipoprotein E and its impact on HDL cholesterol levels.
Clinical biochemistry.
2017 Sep; 50(13-14):777-783. doi:
10.1016/j.clinbiochem.2017.03.021. [PMID: 28366823] - Chetphilin Suriyasak, Keisuke Harano, Koichiro Tanamachi, Kazuhiro Matsuo, Aina Tamada, Mari Iwaya-Inoue, Yushi Ishibashi. Reactive oxygen species induced by heat stress during grain filling of rice (Oryza sativa L.) are involved in occurrence of grain chalkiness.
Journal of plant physiology.
2017 Sep; 216(?):52-57. doi:
10.1016/j.jplph.2017.05.015. [PMID: 28575747] - Nuria Fernández-Bautista, Lourdes Fernández-Calvino, Alfonso Muñoz, M Mar Castellano. HOP3, a member of the HOP family in Arabidopsis, interacts with BiP and plays a major role in the ER stress response.
Plant, cell & environment.
2017 Aug; 40(8):1341-1355. doi:
10.1111/pce.12927. [PMID: 28155228] - Jemmyson Romário de Jesus, Rafael da Silva Fernandes, Gustavo de Souza Pessôa, Ivo Milton Raimundo, Marco Aurélio Zezzi Arruda. Depleting high-abundant and enriching low-abundant proteins in human serum: An evaluation of sample preparation methods using magnetic nanoparticle, chemical depletion and immunoaffinity techniques.
Talanta.
2017 Aug; 170(?):199-209. doi:
10.1016/j.talanta.2017.03.091. [PMID: 28501159] - Matthew E Albertolle, Donghak Kim, Leslie D Nagy, Chul-Ho Yun, Ambra Pozzi, Üzen Savas, Eric F Johnson, F Peter Guengerich. Heme-thiolate sulfenylation of human cytochrome P450 4A11 functions as a redox switch for catalytic inhibition.
The Journal of biological chemistry.
2017 07; 292(27):11230-11242. doi:
10.1074/jbc.m117.792200. [PMID: 28533430] - Loren Honaas, Elena Kahn. A practical examination of RNA isolation methods for European pear (Pyrus communis).
BMC research notes.
2017 Jun; 10(1):237. doi:
10.1186/s13104-017-2564-2. [PMID: 28662720] - Dennis R Goulet, Adam Zwolak, Mark L Chiu, Abhinav Nath, William M Atkins. Diffusion of Soluble Aggregates of THIOMABs and Bispecific Antibodies in Serum.
Biochemistry.
2017 05; 56(17):2251-2260. doi:
10.1021/acs.biochem.6b01097. [PMID: 28394577] - Fernanda M Lopes, Leonardo Lisbôa da Motta, Marco A De Bastiani, Bianca Pfaffenseller, Bianca W Aguiar, Luiz F de Souza, Geancarlo Zanatta, Daiani M Vargas, Patrícia Schönhofen, Giovana F Londero, Liana M de Medeiros, Valder N Freire, Alcir L Dafre, Mauro A A Castro, Richard B Parsons, Fabio Klamt. RA Differentiation Enhances Dopaminergic Features, Changes Redox Parameters, and Increases Dopamine Transporter Dependency in 6-Hydroxydopamine-Induced Neurotoxicity in SH-SY5Y Cells.
Neurotoxicity research.
2017 May; 31(4):545-559. doi:
10.1007/s12640-016-9699-0. [PMID: 28155214] - Jesús Martín Moreno-Hernández, Xitlalli Desideria Hernández-Mancillas, Evelia Lorena Coss Navarrete, Miguel Ángel Mazorra-Manzano, Idalia Osuna-Ruiz, Víctor Alfonso Rodríguez-Tirado, Jesús Aarón Salazar-Leyva. Partial Characterization of the Proteolytic Properties of an Enzymatic Extract From 'Aguama' Bromelia pinguin L. Fruit Grown in Mexico.
Applied biochemistry and biotechnology.
2017 May; 182(1):181-196. doi:
10.1007/s12010-016-2319-x. [PMID: 27830465] - Ditte Hededam Welner, Alex Yi Lin Tsai, Andy M DeGiovanni, Henrik Vibe Scheller, Paul D Adams. X-ray diffraction analysis and in vitro characterization of the UAM2 protein from Oryza sativa.
Acta crystallographica. Section F, Structural biology communications.
2017 04; 73(Pt 4):241-245. doi:
10.1107/s2053230x17004587. [PMID: 28368284] - Zhihua Wu, Jun Lian, Ruifang Zhao, Kun Li, Xin Li, Anshu Yang, Ping Tong, Hongbing Chen. Ara h 2 cross-linking catalyzed by MTGase decreases its allergenicity.
Food & function.
2017 Mar; 8(3):1195-1203. doi:
10.1039/c6fo01365a. [PMID: 28224143] - Lingzhi Zhao, Liu Zhao, Yanqing Miao, Chunye Liu, Chenxiao Zhang. A Colorimetric Sensor for the Highly Selective Detection of Sulfide and 1,4-Dithiothreitol Based on the In Situ Formation of Silver Nanoparticles Using Dopamine.
Sensors (Basel, Switzerland).
2017 Mar; 17(3):. doi:
10.3390/s17030626. [PMID: 28335506] - J Wang, J R Meade, N K Brown, J G Weidner, S R Marino. EDTA is superior to DTT treatment for overcoming the prozone effect in HLA antibody testing.
HLA.
2017 02; 89(2):82-89. doi:
10.1111/tan.12950. [PMID: 28102038] - Tayita Suttirojpattana, Tamas Somfai, Satoko Matoba, Rangsun Parnpai, Takashi Nagai, Masaya Geshi. Effect of medium additives during liquid storage on developmental competence of in vitro matured bovine oocytes.
Animal science journal = Nihon chikusan Gakkaiho.
2017 Feb; 88(2):231-240. doi:
10.1111/asj.12623. [PMID: 27169667] - Flavien Zannini, Jérémy Couturier, Olivier Keech, Nicolas Rouhier. In Vitro Alkylation Methods for Assessing the Protein Redox State.
Methods in molecular biology (Clifton, N.J.).
2017; 1653(?):51-64. doi:
10.1007/978-1-4939-7225-8_4. [PMID: 28822125] - Chia-Wen Tsai, Mei-Due Yang, Te-Chun Hsia, Wen-Shin Chang, Chin-Mu Hsu, Yi-Hsien Hsieh, Jing-Gung Chung, Da-Tian Bau. Dithiothreitol enhanced arsenic-trioxide-induced cell apoptosis in cultured oral cancer cells via mitochondrial dysfunction and endoplasmic reticulum stress.
Environmental toxicology.
2017 Jan; 32(1):17-27. doi:
10.1002/tox.22208. [PMID: 26494474] - Thomas S Weiss, Madeleine Lupke, Sara Ibrahim, Christa Buechler, Julia Lorenz, Petra Ruemmele, Ute Hofmann, Michael Melter, Rania Dayoub. Attenuated lipotoxicity and apoptosis is linked to exogenous and endogenous augmenter of liver regeneration by different pathways.
PloS one.
2017; 12(9):e0184282. doi:
10.1371/journal.pone.0184282. [PMID: 28877220] - Daniel R Beriault, Vi T Dang, Lexy H Zhong, Christina I Petlura, Cameron S McAlpine, Yuanyuan Shi, Geoff H Werstuck. Glucosamine induces ER stress by disrupting lipid-linked oligosaccharide biosynthesis and N-linked protein glycosylation.
American journal of physiology. Endocrinology and metabolism.
2017 01; 312(1):E48-E57. doi:
10.1152/ajpendo.00275.2016. [PMID: 27879249] - Claudia I Chapuy, Maria D Aguad, Rachel T Nicholson, James P AuBuchon, Claudia S Cohn, Meghan Delaney, Mark K Fung, Meredith Unger, Parul Doshi, Michael F Murphy, Larry J Dumont, Richard M Kaufman. International validation of a dithiothreitol (DTT)-based method to resolve the daratumumab interference with blood compatibility testing.
Transfusion.
2016 12; 56(12):2964-2972. doi:
10.1111/trf.13789. [PMID: 27600566] - Muthukumar Kannan, Chinnarasu Sivaprakasam, William A Prinz, Vasanthi Nachiappan. Endoplasmic reticulum stress affects the transport of phosphatidylethanolamine from mitochondria to the endoplasmic reticulum in S.cerevisiae.
Biochimica et biophysica acta.
2016 12; 1861(12 Pt A):1959-1967. doi:
10.1016/j.bbalip.2016.09.015. [PMID: 27678054] - Mahmoud Omidi, Hossein Niknahad, Afshin Mohammadi-Bardbori. Dithiothreitol (DTT) rescues mitochondria from nitrofurantoin-induced mitotoxicity in rat.
Journal of biochemical and molecular toxicology.
2016 Dec; 30(12):588-592. doi:
10.1002/jbt.21825. [PMID: 27373690] - Ying Chen, Zhengqing Xu, Difeng Zhu, Xinfeng Tao, Yuqian Gao, Hong Zhu, Zhengwei Mao, Jun Ling. Gold nanoparticles coated with polysarcosine brushes to enhance their colloidal stability and circulation time in vivo.
Journal of colloid and interface science.
2016 Dec; 483(?):201-210. doi:
10.1016/j.jcis.2016.08.038. [PMID: 27552428] - Seok-Young Oh, Yong-Deuk Seo. Polymer/biomass-derived biochar for use as a sorbent and electron transfer mediator in environmental applications.
Bioresource technology.
2016 Oct; 218(?):77-83. doi:
10.1016/j.biortech.2016.06.073. [PMID: 27347801] - Virginia Castel, Svetlana Zivanovic, Juan L Jurat-Fuentes, Liliana G Santiago, Amelia C Rubiolo, Carlos R Carrara, Federico M Harte. Chromatographic fractionation and molecular mass characterization of Cercidium praecox (Brea) gum.
Journal of the science of food and agriculture.
2016 Oct; 96(13):4345-50. doi:
10.1002/jsfa.7642. [PMID: 26801963] - J E Araújo, S Jorge, F Teixeira E Costa, A Ramos, C Lodeiro, H M Santos, J L Capelo. A cost-effective method to get insight into the peritoneal dialysate effluent proteome.
Journal of proteomics.
2016 08; 145(?):207-213. doi:
10.1016/j.jprot.2016.05.010. [PMID: 27216641] - Belén Naranjo, Clara Mignée, Anja Krieger-Liszkay, Dámaso Hornero-Méndez, Lourdes Gallardo-Guerrero, Francisco Javier Cejudo, Marika Lindahl. The chloroplast NADPH thioredoxin reductase C, NTRC, controls non-photochemical quenching of light energy and photosynthetic electron transport in Arabidopsis.
Plant, cell & environment.
2016 Apr; 39(4):804-22. doi:
10.1111/pce.12652. [PMID: 26476233] - Mark J Richards, Chih-Yun Hsia, Rohit R Singh, Huma Haider, Julia Kumpf, Toshimitsu Kawate, Susan Daniel. Membrane Protein Mobility and Orientation Preserved in Supported Bilayers Created Directly from Cell Plasma Membrane Blebs.
Langmuir : the ACS journal of surfaces and colloids.
2016 Mar; 32(12):2963-74. doi:
10.1021/acs.langmuir.5b03415. [PMID: 26812542] - Yasmine Amitay, Hilary Shmeeda, Yogita Patil, Jenny Gorin, Dina Tzemach, Lidia Mak, Patricia Ohana, Alberto Gabizon. Pharmacologic Studies of a Prodrug of Mitomycin C in Pegylated Liposomes (Promitil(®)): High Stability in Plasma and Rapid Thiolytic Prodrug Activation in Tissues.
Pharmaceutical research.
2016 Mar; 33(3):686-700. doi:
10.1007/s11095-015-1819-7. [PMID: 26572644] - Xiaochen Yang, Renu Srivastava, Stephen H Howell, Diane C Bassham. Activation of autophagy by unfolded proteins during endoplasmic reticulum stress.
The Plant journal : for cell and molecular biology.
2016 Jan; 85(1):83-95. doi:
10.1111/tpj.13091. [PMID: 26616142] - Reza Heidari, Vahid Taheri, Hamid Reza Rahimi, Babak Shirazi Yeganeh, Hossein Niknahad, Asma Najibi. Sulfasalazine-induced renal injury in rats and the protective role of thiol-reductants.
Renal failure.
2016; 38(1):137-41. doi:
10.3109/0886022x.2015.1096731. [PMID: 26479898] - Valentina Ganeva, Debora Stefanova, Boyana Angelova, Bojidar Galutzov, Isabel Velasco, Miguel Arévalo-Rodríguez. Electroinduced release of recombinant β-galactosidase from Saccharomyces cerevisiae.
Journal of biotechnology.
2015 Oct; 211(?):12-9. doi:
10.1016/j.jbiotec.2015.06.418. [PMID: 26142064] - Marlies A Lambrecht, Ine Rombouts, Lotte Van Kelst, Jan A Delcour. Impact of extraction and elution media on non-size effects in size exclusion chromatography of proteins.
Journal of chromatography. A.
2015 Oct; 1415(?):100-7. doi:
10.1016/j.chroma.2015.08.070. [PMID: 26365913] - Racha Al-Halabi, Raghida Abou Merhi, Saritha Chakilam, Chirine El-Baba, Eva Hamade, Pietro Di Fazio, Matthias Ocker, Regine Schneider-Stock, Hala Gali-Muhtasib. Gallotannin is a DNA damaging compound that induces senescence independently of p53 and p21 in human colon cancer cells.
Molecular carcinogenesis.
2015 Oct; 54(10):1037-50. doi:
10.1002/mc.22172. [PMID: 24798519] - Vera A Borzova, Kira A Markossian, Dmitriy A Kara, Boris Kurganov. Kinetic regime of dithiothreitol-induced aggregation of bovine serum albumin.
International journal of biological macromolecules.
2015 Sep; 80(?):130-8. doi:
10.1016/j.ijbiomac.2015.06.040. [PMID: 26116389] - Yong-Xing Zhu, Xuan-Bin Xu, Yan-Hong Hu, Wei-Hua Han, Jun-Liang Yin, Huan-Li Li, Hai-Jun Gong. Silicon improves salt tolerance by increasing root water uptake in Cucumis sativus L.
Plant cell reports.
2015 Sep; 34(9):1629-46. doi:
10.1007/s00299-015-1814-9. [PMID: 26021845] - Jin Young Lee, Byung Ho Lee, Nam Doo Kim, Joo Young Lee. Celastrol blocks binding of lipopolysaccharides to a Toll-like receptor4/myeloid differentiation factor2 complex in a thiol-dependent manner.
Journal of ethnopharmacology.
2015 Aug; 172(?):254-60. doi:
10.1016/j.jep.2015.06.028. [PMID: 26116162] - Long Wang, Huayang Guo, Nan Zhang, Zhenhua Ma, Shigui Jiang, Dianchang Zhang. Molecular characterization and functional analysis of a peroxiredoxin 1 cDNA from golden pompano (Trachinotus ovatus).
Developmental and comparative immunology.
2015 Aug; 51(2):261-70. doi:
10.1016/j.dci.2015.03.011. [PMID: 25889122] - Carlos Henriquez-Valencia, Adrian A Moreno, Omar Sandoval-Ibañez, Irina Mitina, Francisca Blanco-Herrera, Nicolas Cifuentes-Esquivel, Ariel Orellana. bZIP17 and bZIP60 Regulate the Expression of BiP3 and Other Salt Stress Responsive Genes in an UPR-Independent Manner in Arabidopsis thaliana.
Journal of cellular biochemistry.
2015 Aug; 116(8):1638-45. doi:
10.1002/jcb.25121. [PMID: 25704669] - Sarvenaz Sarabipour, Robin B Chan, Bowen Zhou, Gilbert Di Paolo, Kalina Hristova. Analytical characterization of plasma membrane-derived vesicles produced via osmotic and chemical vesiculation.
Biochimica et biophysica acta.
2015 Jul; 1848(7):1591-8. doi:
10.1016/j.bbamem.2015.04.002. [PMID: 25896659] - Kathleen Mommaerts, Ignacio Sanchez, Fay Betsou, William Mathieson. Replacing β-mercaptoethanol in RNA extractions.
Analytical biochemistry.
2015 Jun; 479(?):51-3. doi:
10.1016/j.ab.2015.03.027. [PMID: 25841674] - Claudia I Chapuy, Rachel T Nicholson, Maria D Aguad, Bjoern Chapuy, Jacob P Laubach, Paul G Richardson, Parul Doshi, Richard M Kaufman. Resolving the daratumumab interference with blood compatibility testing.
Transfusion.
2015 Jun; 55(6 Pt 2):1545-54. doi:
10.1111/trf.13069. [PMID: 25764134] - Mu Yang, Colina Dutta, Ashutosh Tiwari. Disulfide-bond scrambling promotes amorphous aggregates in lysozyme and bovine serum albumin.
The journal of physical chemistry. B.
2015 Mar; 119(10):3969-81. doi:
10.1021/acs.jpcb.5b00144. [PMID: 25689578] - Hong-Tao Yang, Li-Jie Luo, Wen-Jia Chen, Lei Zhao, Chao-Shu Tang, Yong-Fen Qi, Jing Zhang. IL-15 expression increased in response to treadmill running and inhibited endoplasmic reticulum stress in skeletal muscle in rats.
Endocrine.
2015 Feb; 48(1):152-63. doi:
10.1007/s12020-014-0233-y. [PMID: 24647688] - Hua Jiang, Jianfeng Zou, Hui Zhang, Weijun Fu, Tianmei Zeng, Hejing Huang, Fan Zhou, Jian Hou. Unfolded protein response inducers tunicamycin and dithiothreitol promote myeloma cell differentiation mediated by XBP-1.
Clinical and experimental medicine.
2015 Feb; 15(1):85-96. doi:
10.1007/s10238-013-0269-y. [PMID: 24356728] - T I Omotayo, G S Akinyemi, P A Omololu, B O Ajayi, A A Akindahunsi, J B T Rocha, I J Kade. Possible involvement of membrane lipids peroxidation and oxidation of catalytically essential thiols of the cerebral transmembrane sodium pump as component mechanisms of iron-mediated oxidative stress-linked dysfunction of the pump's activity.
Redox biology.
2015; 4(?):234-41. doi:
10.1016/j.redox.2014.12.015. [PMID: 25618580] - Zhao-Xia Ma, Ya-Jun Leng, Guang-Xia Chen, Peng-Min Zhou, De Ye, Li-Qun Chen. The THERMOSENSITIVE MALE STERILE 1 Interacts with the BiPs via DnaJ Domain and Stimulates Their ATPase Enzyme Activities in Arabidopsis.
PloS one.
2015; 10(7):e0132500. doi:
10.1371/journal.pone.0132500. [PMID: 26186593] - Juan Parra-Rojas, Adrian A Moreno, Irina Mitina, Ariel Orellana. The dynamic of the splicing of bZIP60 and the proteins encoded by the spliced and unspliced mRNAs reveals some unique features during the activation of UPR in Arabidopsis thaliana.
PloS one.
2015; 10(4):e0122936. doi:
10.1371/journal.pone.0122936. [PMID: 25860807] - Renata Smulik, Dawid Dębski, Jacek Zielonka, Bartosz Michałowski, Jan Adamus, Andrzej Marcinek, Balaraman Kalyanaraman, Adam Sikora. Nitroxyl (HNO) reacts with molecular oxygen and forms peroxynitrite at physiological pH. Biological Implications.
The Journal of biological chemistry.
2014 Dec; 289(51):35570-81. doi:
10.1074/jbc.m114.597740. [PMID: 25378389] - Adèle Mennerat, Ben C Sheldon. How to deal with PCR contamination in molecular microbial ecology.
Microbial ecology.
2014 Nov; 68(4):834-41. doi:
10.1007/s00248-014-0453-y. [PMID: 25004997] - Samuel Morisse, Laure Michelet, Mariette Bedhomme, Christophe H Marchand, Matteo Calvaresi, Paolo Trost, Simona Fermani, Mirko Zaffagnini, Stéphane D Lemaire. Thioredoxin-dependent redox regulation of chloroplastic phosphoglycerate kinase from Chlamydomonas reinhardtii.
The Journal of biological chemistry.
2014 Oct; 289(43):30012-24. doi:
10.1074/jbc.m114.597997. [PMID: 25202015] - Marta Pérez-Martín, María Esther Pérez-Pérez, Stéphane D Lemaire, José L Crespo. Oxidative stress contributes to autophagy induction in response to endoplasmic reticulum stress in Chlamydomonas reinhardtii.
Plant physiology.
2014 Oct; 166(2):997-1008. doi:
10.1104/pp.114.243659. [PMID: 25143584] - Xiaoning Liu, Jiamei Wu, Hao Liu, Na Zong, Jun Zhao. RoGFP1 is a quantitative biosensor in maize cells for cellular redox changes caused by environmental and endogenous stimuli.
Biochemical and biophysical research communications.
2014 Sep; 452(3):503-8. doi:
10.1016/j.bbrc.2014.08.107. [PMID: 25173931]