Angustifoline (BioDeep_00000000791)

   

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


(1R,2R,9S,10S)-10-Prop-2-enyl-7,11-diazatricyclo[7.3.1.02,7]tridecan-6-one

化学式: C14H22N2O (234.1732)
中文名称: 4-（丙-2-烯-1-基）十氢-8H-1,5-甲基吡啶并[1,2-a][1,5]重氮嗪-8-酮
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 43.7%

分子结构信息

SMILES: C=CCC1C2CC(CN1)C3CCCC(=O)N3C2
InChI: InChI=1S/C14H22N2O/c1-2-4-12-11-7-10(8-15-12)13-5-3-6-14(17)16(13)9-11/h2,10-13,15H,1,3-9H2/t10-,11+,12+,13-/m1/s1

描述信息

Angustifoline is a member of quinolizidines and a cyclic ketone.
4-(Prop-2-en-1-yl)decahydro-8H-1,5-methanopyrido[1,2-a][1,5]diazocin-8-one is a natural product found in Haplophyllum thesioides, Lupinus hintonii, and other organisms with data available.
CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 54
CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 18
CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 33
CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 40
CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 25
CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 10
CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 3

同义名列表

6 个代谢物同义名

(1R,2R,9S,10S)-10-Prop-2-enyl-7,11-diazatricyclo[7.3.1.02,7]tridecan-6-one; 4-(Prop-2-en-1-yl)decahydro-8H-1,5-methanopyrido[1,2-a][1,5]diazocin-8-one; Angustifoline; (2R,10S)-10-prop-2-enyl-7,11-diazatricyclo[7.3.1.02,7]tridecan-6-one; Angustifoline; 4-(Prop-2-en-1-yl)decahydro-8H-1,5-methanopyrido[1,2-a][1,5]diazocin-8-one



数据库引用编号

50 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

100 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 4 ARG1, BECN1, SCARB1, TFDP3
Golgi apparatus, trans-Golgi network membrane 1 BECN1
Peripheral membrane protein 1 BECN1
Endosome membrane 1 BECN1
Endoplasmic reticulum membrane 1 BECN1
Mitochondrion membrane 1 BECN1
Cytoplasmic vesicle, autophagosome 1 BECN1
Nucleus 4 ARG1, BECN1, MKI67, TFDP3
autophagosome 1 BECN1
cytosol 2 ARG1, BECN1
dendrite 1 BECN1
mitochondrial membrane 1 BECN1
nuclear body 2 BECN1, MKI67
phagocytic vesicle 1 BECN1
phosphatidylinositol 3-kinase complex, class III 1 BECN1
trans-Golgi network 1 BECN1
nucleoplasm 1 MKI67
Cell membrane 1 SCARB1
Cytoplasmic granule 1 ARG1
Multi-pass membrane protein 1 SCARB1
cell surface 1 SCARB1
lysosomal membrane 1 SCARB1
Lysosome 1 SCARB1
endosome 1 BECN1
plasma membrane 1 SCARB1
Membrane 2 MKI67, SCARB1
axon 1 CCK
caveola 1 SCARB1
extracellular exosome 1 SCARB1
endoplasmic reticulum 1 BECN1
extracellular space 2 ARG1, CCK
intracellular membrane-bounded organelle 1 SCARB1
Secreted 1 CCK
extracellular region 2 ARG1, CCK
transcription regulator complex 1 TFDP3
nucleolus 1 MKI67
chromatin 1 TFDP3
Chromosome 1 MKI67
Nucleus, nucleolus 1 MKI67
Membrane, caveola 1 SCARB1
phagophore assembly site 1 BECN1
phosphatidylinositol 3-kinase complex, class III, type I 1 BECN1
phosphatidylinositol 3-kinase complex, class III, type II 1 BECN1
specific granule lumen 1 ARG1
endocytic vesicle membrane 1 SCARB1
azurophil granule lumen 1 ARG1
cytoplasmic side of mitochondrial outer membrane 1 BECN1
[Beclin-1-C 35 kDa]: Mitochondrion 1 BECN1
[Beclin-1-C 37 kDa]: Mitochondrion 1 BECN1


文献列表

  • M C Robbins, D S Petterson, P G Brantom. A 90-day feeding study of the alkaloids of Lupinus angustifolius in the rat. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 1996 Aug; 34(8):679-86. doi: 10.1016/0278-6915(96)00040-3. [PMID: 8883468]