Lycopodine (BioDeep_00000007659)

   

natural product


代谢物信息卡片


12-Epilycopodine

化学式: C16H25NO (247.193604)
中文名称: 石松鹼
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1CC2CC(=O)C3CCCN4C3(C1)C2CCC4
InChI: InChI=1S/C16H25NO/c1-11-8-12-9-15(18)14-5-3-7-17-6-2-4-13(12)16(14,17)10-11/h11-14H,2-10H2,1H3/t11-,12+,13-,14-,16-/m1/s1

描述信息

同义名列表

2 个代谢物同义名

Lycopodine; 12-Epilycopodine



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

172 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Zhen Yang, Qingsheng Yin, Jing Ma, Changshuo Yang, Yuanyuan Sheng, Lili Song, Tan Pang, Pengwei Zhuang, Hong Guo, Yanjun Zhang. Screen the Effective Components of Lycopodii herba on Rheumatoid Arthritis with the Aid of Spectrum-Effect Relationship and Uncover its Potential Mechanism. Inflammation. 2020 Dec; 43(6):2087-2097. doi: 10.1007/s10753-020-01276-z. [PMID: 32914364]
  • Yu Tang, Juan Xiong, Yike Zou, Wei Wang, Chao Huang, Hai-Yan Zhang, Jin-Feng Hu. Annotinolide F and lycoannotines A-I, further Lycopodium alkaloids from Lycopodium annotinum. Phytochemistry. 2017 Nov; 143(?):1-11. doi: 10.1016/j.phytochem.2017.07.003. [PMID: 28738241]
  • Yu Tang, Juan Xiong, Yike Zou, Hai-Yan Zhang, Jin-Feng Hu. Palhicerines A-F, Lycopodium alkaloids from the club moss Palhinhaea cernua. Phytochemistry. 2016 Nov; 131(?):130-139. doi: 10.1016/j.phytochem.2016.08.010. [PMID: 27576047]
  • Ke Pan, Jian-Guang Luo, Ling-Yi Kong. A new Lycopodium alkaloid from Phlegmariurus fargesii. Chinese journal of natural medicines. 2014 May; 12(5):373-6. doi: 10.1016/s1875-5364(14)60046-7. [PMID: 24856761]
  • Eduardo Luis Konrath, María Gabriela Ortega, Sérgio de Loreto Bordignon, Miriam Anders Apel, Amélia Teresinha Henriques, José Luis Cabrera. Alkaloid profiling and anticholinesterase activity of South American Lycopodiaceae species. Journal of enzyme inhibition and medicinal chemistry. 2013 Feb; 28(1):218-22. doi: 10.3109/14756366.2011.633908. [PMID: 22117191]
  • Eduardo Luis Konrath, Bruna Medeiros Neves, Paula Santana Lunardi, Carolina Dos Santos Passos, André Simões-Pires, María Gabriela Ortega, Carlos Alberto Gonçalves, José L Cabrera, José Cláudio Fonseca Moreira, Amélia T Henriques. Investigation of the in vitro and ex vivo acetylcholinesterase and antioxidant activities of traditionally used Lycopodium species from South America on alkaloid extracts. Journal of ethnopharmacology. 2012 Jan; 139(1):58-67. doi: 10.1016/j.jep.2011.10.042. [PMID: 22108682]
  • Hongmei Luo, Ying Li, Chao Sun, Qiong Wu, Jingyuan Song, Yongzhen Sun, André Steinmetz, Shilin Chen. Comparison of 454-ESTs from Huperzia serrata and Phlegmariurus carinatus reveals putative genes involved in lycopodium alkaloid biosynthesis and developmental regulation. BMC plant biology. 2010 Sep; 10(?):209. doi: 10.1186/1471-2229-10-209. [PMID: 20854695]
  • Sushil Kumar Mandal, Raktim Biswas, Soumya Sundar Bhattacharyya, Saili Paul, Suman Dutta, Surajit Pathak, Anisur Rahman Khuda-Bukhsh. Lycopodine from Lycopodium clavatum extract inhibits proliferation of HeLa cells through induction of apoptosis via caspase-3 activation. European journal of pharmacology. 2010 Jan; 626(2-3):115-22. doi: 10.1016/j.ejphar.2009.09.033. [PMID: 19786013]
  • Raimana Ho, Niloufar Marsousi, Philippe Eugster, Jean-Pierre Bianchini, Phila Raharivelomanana. Detection by UPLC/ESI-TOF-MS of alkaloids in three Lycopodiaceae species from French Polynesia and their anticholinesterase activity. Natural product communications. 2009 Oct; 4(10):1349-52. doi: . [PMID: 19911569]
  • Ilkay Orhan, Berrin Ozcelik, Sinem Aslan, Murat Kartal, Taner Karaoglu, Bilge Sener, Salih Terzioglu, M Iqbal Choudhary. In vitro biological activity screening of Lycopodium complanatum L. ssp. chamaecyparissus (A. Br.) Doll. Natural product research. 2009; 23(6):514-26. doi: 10.1080/14786410802163743. [PMID: 19384728]
  • Ilkay Orhan, Esra Küpeli, Bilge Sener, Erdem Yesilada. Appraisal of anti-inflammatory potential of the clubmoss, Lycopodium clavatum L. Journal of ethnopharmacology. 2007 Jan; 109(1):146-50. doi: 10.1016/j.jep.2006.07.018. [PMID: 16962272]
  • Xiaoqiang Ma, David R Gang. The Lycopodium alkaloids. Natural product reports. 2004 Dec; 21(6):752-72. doi: 10.1039/b409720n. [PMID: 15565253]
  • M G Ortega, A M Agnese, J L Cabrera. Anticholinesterase activity in an alkaloid extract of Huperzia saururus. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2004 Sep; 11(6):539-43. doi: 10.1016/j.phymed.2003.07.006. [PMID: 15500266]
  • Hiromitsu Takayama, Kazuaki Katakawa, Mariko Kitajima, Kentaro Yamaguchi, Norio Aimi. Ten new Lycopodium alkaloids having the lycopodane skeleton isolated from Lycopodium serratum Thunb. Chemical & pharmaceutical bulletin. 2003 Oct; 51(10):1163-9. doi: 10.1248/cpb.51.1163. [PMID: 14519922]
  • H J Englert, C H Hawkes, M L Boey, G J Derue, S Loizou, E N Harris, A E Gharavi, R G Hull, G R Hughes. Degos' disease: association with anticardiolipin antibodies and the lupus anticoagulant. British medical journal (Clinical research ed.). 1984 Sep; 289(6445):576. doi: 10.1136/bmj.289.6445.576. [PMID: 6432197]
  • J Posner, A Bye, S Jeal, A W Peck, P Whiteman. Alcohol and bupropion pharmacokinetics in healthy male volunteers. European journal of clinical pharmacology. 1984; 26(5):627-30. doi: 10.1007/bf00543497. [PMID: 6432553]