Sodium_salicylate (BioDeep_00000000739)
PANOMIX_OTCML-2023 Chemicals and Drugs
代谢物信息卡片
Benzoic acid,2-hydroxy-,monosodium salt,coupled with 4-amino-5-hydroxy-2,7-naphthalenedisulfonic acid,diazotized 2-(4-aminophenyl)-1H-benzimidazol-5-amine and diazotized 4-nitrobenzenamine,sodium
化学式: C7H5NaO3 (160.0136)
中文名称: 水杨酸钠
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 86.76%
分子结构信息
SMILES: C1=CC=C(C(=C1)C(=O)[O-])O.[Na+]
InChI: /q
描述信息
Sodium salicylate is an organic molecular entity.
Sodium Salicylate is the sodium salt of salicylic acid. As a nonsteroidal anti-inflammatory drug (NSAID), sodium salicylate irreversibly acetylates cyclooxygenases I and II, thereby inhibiting prostaglandin synthesis and associated inflammation and pain. This agent may also activate mitogen-activated protein kinase (p38MAPK), thereby inducing apoptosis in cancer cells. (NCI04)
A non-steroidal anti-inflammatory agent that is less effective than equal doses of ASPIRIN in relieving pain and reducing fever. However, individuals who are hypersensitive to ASPIRIN may tolerate sodium salicylate. In general, this salicylate produces the same adverse reactions as ASPIRIN, but there is less occult gastrointestinal bleeding. (From AMA Drug Evaluations Annual, 1992, p120)
See also: Salicylic Acid (has active moiety); Methenamine; Sodium Salicylate (component of) ... View More ...
N - Nervous system > N02 - Analgesics > N02B - Other analgesics and antipyretics > N02BA - Salicylic acid and derivatives
D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors
D000893 - Anti-Inflammatory Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D012459 - Salicylates
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
D004791 - Enzyme Inhibitors
Sodium Salicylate (Salicylic acid sodium salt) inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation[1]. Sodium Salicylate is also a S6K inhibitor.Sodium Salicylate is a NF-κB inhibitor that decreases inflammatory gene expression and improves repair in aged muscle[4].
Sodium Salicylate (Salicylic acid sodium salt) inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation[1]. Sodium Salicylate is also a S6K inhibitor.Sodium Salicylate is a NF-κB inhibitor that decreases inflammatory gene expression and improves repair in aged muscle[4].
Sodium Salicylate (Salicylic acid sodium salt) inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation[1]. Sodium Salicylate is also a S6K inhibitor.Sodium Salicylate is a NF-κB inhibitor that decreases inflammatory gene expression and improves repair in aged muscle[4].
同义名列表
86 个代谢物同义名
Benzoic acid,2-hydroxy-,monosodium salt,coupled with 4-amino-5-hydroxy-2,7-naphthalenedisulfonic acid,diazotized 2-(4-aminophenyl)-1H-benzimidazol-5-amine and diazotized 4-nitrobenzenamine,sodium; Benzoic acid, 2-hydroxy-, monosodium salt, coupled with 4-amino-1-naphthalenesulfonic acid and diazotized 2-(4-aminophenyl)-1H-benzimidazol-5-amine, sodium salt; Sodium salicylate, United States Pharmacopeia (USP) Reference Standard; Sodium salicylate, European Pharmacopoeia (EP) Reference Standard; Salicylic acid sodium salt;2-Hydroxybenzoic acid sodium salt; Sodium salicylate, meets USP testing specifications; Sodium salicylate, Vetec(TM) reagent grade, 99\\%; Sodium salicylate, SAJ special grade, >=99.5\\%; Sodium salicylate, puriss. p.a., >=99.5\\% (NT); Sodium salicylate, tested according to Ph.Eur.; Sodium salicylate, SAJ first grade, >=99.5\\%; Sodium salicylate, ReagentPlus(R), >=99.5\\%; 2,4-DIMETHOXYPHENYLBORONICACID,PINACOLESTER; Benzoic acid, 2-hydroxy-, monosodium salt; o-Hydroxybenzoic acid, sodium salt; SODIUM SALICYLATE (USP MONOGRAPH); SODIUM SALICYLATE [USP MONOGRAPH]; SODIUM SALICYLATE (EP MONOGRAPH); SODIUM SALICYLATE [EP MONOGRAPH]; SALICYLIC ACID SODIUM SALT [MI]; Sodium salicylate, p.a., 99.5\\%; NATRII SALICYLAS [WHO-IP LATIN]; Sodium salicylate (JP17/USP); Monosodium 2-hydroxybenzoate; Salicylic acid, sodium salt; Sodium salicylate [USP:JAN]; ABBQHOQBGMUPJH-UHFFFAOYSA-M; Sodium salicylate (USP:JAN); SODIUM SALICYLATE (USP-RS); SALICYLATE SODIUM [WHO-DD]; SODIUM SALICYLATE [WHO-IP]; Salicylic acid sodium salt; Natrium salicylat [German]; SODIUM SALICYLATE [USP-RS]; SODIUM SALICYLATE (MART.); sodium;2-carboxyphenolate; SODIUM SALICYLATE [VANDF]; SODIUM SALICYLATE [MART.]; NATRUM SALICYLICUM [HPUS]; SODIUM SALICYLATE [INCI]; Sodium 2-hydroxybenzoate; Sodium o-hydroxybenzoate; sodium;2-hydroxybenzoate; Sodium salicylate, 99\\%; SODIUM SALICYLATE [JAN]; salicylic acid sodium; Monosodium salicylate; Salicylate, sodium; Natrum salicylicum; Natrium salicylat; salicylate sodium; Sodium Salicylate; Spectrum5_001120; Spectrum3_000900; Spectrum2_001945; Natrii salicylas; Spectrum4_000995; UNII-WIQ1H85SYP; Enterosalicyl; Tox21_200411; KBio3_001820; Parbocyl-rev; Idocyl novum; Enterosalil; SaliGard 60; Neo-salicyl; CAS-54-21-7; Kerasalicyl; WIQ1H85SYP; UNI-SOL 60; Glutosalyl; Entrosalyl; Pro-Prin; Diuretin; Magsalyl; Salsonin; Salisod; Nadisal; Kerosal; Alysine; UNI-SOL; Aroall; Clin; Salicylic acid (sodium salt); 2-Hydroxybenzoic acid (sodium salt); Sodium salicylate
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:9180
- KEGG: C07587
- KEGGdrug: D00566
- KEGGdrug: D83111
- PubChem: 16760658
- Metlin: METLIN66691
- ChEMBL: CHEMBL447868
- Wikipedia: Sodium_salicylate
- MeSH: Sodium Salicylate
- ChemIDplus: 0000054217
- CAS: 90218-94-3
- CAS: 90218-97-6
- CAS: 54-21-7
- medchemexpress: HY-B0167A
- PubChem: 9789
- KNApSAcK: 9180
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Aohui Han, Cuiling Wang, Jingchong Li, Li Xu, Xiaoyan Guo, Weiguo Li, Feng Zhou, Runqiang Liu. Physiological mechanism of sodium salicylate and folcisteine on alleviating salt stress in wheat seedlings.
Scientific reports.
2023 12; 13(1):22869. doi:
10.1038/s41598-023-49629-6. [PMID: 38129459] - Q Lu, J N Zhang, Y Huo, Q Xia, J Y Jiao, M Li. [Susceptibility and mechanism of sodium salicylate-induced tinnitus model in low estrogen rats].
Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery.
2022 Dec; 57(12):1479-1483. doi:
10.3760/cma.j.cn115330-20220322-00125. [PMID: 36707953] - Yasmina M Abd-Elhakim, Sabry M Abdel-Motal, Seham M Malhat, Hend I Mostafa, Walied M Ibrahim, Rasha R Beheiry, Attia A A Moselhy, Enas N Said. Curcumin attenuates gentamicin and sodium salicylate ototoxic effects by modulating the nuclear factor-kappaB and apoptotic pathways in rats.
Environmental science and pollution research international.
2022 Dec; 29(60):89954-89968. doi:
10.1007/s11356-022-21932-1. [PMID: 35859240] - Sarina Kajani, Sean Curley, Marcella E O'Reilly, Xiaofei Yin, Eugene T Dillon, Weili Guo, Kanishka N Nilaweera, Lorraine Brennan, Helen M Roche, Fiona C McGillicuddy. Sodium salicylate rewires hepatic metabolic pathways in obesity and attenuates IL-1β secretion from adipose tissue: The implications for obesity-impaired reverse cholesterol transport.
Molecular metabolism.
2022 02; 56(?):101425. doi:
10.1016/j.molmet.2021.101425. [PMID: 34954383] - C M Ylioja, A J Carpenter, L K Mamedova, K M Daniels, P J Ross, S L Laflin, T H Swartz, B J Bradford. Effects of sodium salicylate and time postpartum on mammary tissue proliferation, gene transcript profile, and DNA methylation.
Journal of dairy science.
2021 Oct; 104(10):11259-11276. doi:
10.3168/jds.2020-20109. [PMID: 34304880] - Beihua Zhong, Shuangtao Ma, Donna H Wang. Ablation of TRPV1 Abolishes Salicylate-Induced Sympathetic Activity Suppression and Exacerbates Salicylate-Induced Renal Dysfunction in Diet-Induced Obesity.
Cells.
2021 05; 10(5):. doi:
10.3390/cells10051234. [PMID: 34069822] - Hui-Ping Tang, Hua-Rui Gong, Xu-Lai Zhang, Yi-Na Huang, Chuan-Yun Wu, Zheng-Quan Tang, Lin Chen, Ming Wang. Sodium salicylate enhances neural excitation via reducing GABAergic transmission in the dentate gyrus area of rat hippocampus in vivo.
Hippocampus.
2021 05; 31(5):512-521. doi:
10.1002/hipo.23312. [PMID: 33580728] - Erik Gerner, Sofia Almqvist, Peter Thomsen, Maria Werthén, Margarita Trobos. Sodium Salicylate Influences the Pseudomonas aeruginosa Biofilm Structure and Susceptibility Towards Silver.
International journal of molecular sciences.
2021 Jan; 22(3):. doi:
10.3390/ijms22031060. [PMID: 33494399] - Yasmina M Abd-Elhakim, Sabry M Abdel-Motal, Seham M Malhat, Hend I Mostafa, Attia A A Moselhy, Rasha R Beheiry, Enas N Said. Curcumin mitigates neurotoxic and neurobehavioral changes of gentamicin and sodium salicylate in rats by adjusting oxidative stress and apoptosis.
Life sciences.
2021 Jan; 265(?):118824. doi:
10.1016/j.lfs.2020.118824. [PMID: 33278387] - Cristina F Malla, Natalia A Mireles, Ana S Ramírez, José B Poveda, María M Tavío. Aspirin, sodium benzoate and sodium salicylate reverse resistance to colistin in Enterobacteriaceae and Pseudomonas aeruginosa.
The Journal of antimicrobial chemotherapy.
2020 12; 75(12):3568-3575. doi:
10.1093/jac/dkaa371. [PMID: 32989461] - Chunyue Yu, Zeqi Su, Yicong Li, Yadong Li, Kaige Liu, Fuhao Chu, Ting Liu, Runhua Chen, Xia Ding. Dysbiosis of gut microbiota is associated with gastric carcinogenesis in rats.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2020 Jun; 126(?):110036. doi:
10.1016/j.biopha.2020.110036. [PMID: 32172061] - Erik Gerner, Sofia Almqvist, Maria Werthén, Margarita Trobos. Sodium salicylate interferes with quorum-sensing-regulated virulence in chronic wound isolates of Pseudomonas aeruginosa in simulated wound fluid.
Journal of medical microbiology.
2020 May; 69(5):767-780. doi:
10.1099/jmm.0.001188. [PMID: 32320374] - M Girard, D Hu, N Pradervand, S Neuenschwander, G Bee. Chestnut extract but not sodium salicylate decreases the severity of diarrhea and enterotoxigenic Escherichia coli F4 shedding in artificially infected piglets.
PloS one.
2020; 15(2):e0214267. doi:
10.1371/journal.pone.0214267. [PMID: 32106264] - Tibor Janda, Magdalena Anna Lejmel, Anna Borbála Molnár, Imre Majláth, Magda Pál, Quang Trung Nguyen, Ngoc Tung Nguyen, Van Nhan Le, Gabriella Szalai. Interaction between elevated temperature and different types of Na-salicylate treatment in Brachypodium dystachion.
PloS one.
2020; 15(1):e0227608. doi:
10.1371/journal.pone.0227608. [PMID: 31931519] - S R Montgomery, L K Mamedova, M Zachut, G Kra, S Häussler, M Vaughn, J Gonzalez, B J Bradford. Effects of sodium salicylate on glucose kinetics and insulin signaling in postpartum dairy cows.
Journal of dairy science.
2019 Feb; 102(2):1617-1629. doi:
10.3168/jds.2018-15312. [PMID: 30591328] - A J Carpenter, C M Ylioja, L K Mamedova, K E Olagaray, B J Bradford. Effects of early postpartum sodium salicylate treatment on long-term milk, intake, and blood parameters of dairy cows.
Journal of dairy science.
2018 Feb; 101(2):1437-1447. doi:
10.3168/jds.2017-13057. [PMID: 29224877] - B Poźniak, K Motykiewicz-Pers, T Grabowski, M Świtała. The influence of rapid growth on sodium salicylate pharmacokinetics in male turkeys.
Journal of veterinary pharmacology and therapeutics.
2018 Feb; 41(1):163-165. doi:
10.1111/jvp.12430. [PMID: 28664587] - Juhyun Oh, Indranil Sinha, Kah Yong Tan, Bernard Rosner, Jonathan M Dreyfuss, Ornela Gjata, Peter Tran, Steven E Shoelson, Amy J Wagers. Age-associated NF-κB signaling in myofibers alters the satellite cell niche and re-strains muscle stem cell function.
Aging.
2016 11; 8(11):2871-2896. doi:
10.18632/aging.101098. [PMID: 27852976] - A J Carpenter, C M Ylioja, C F Vargas, L K Mamedova, L G Mendonça, J F Coetzee, L C Hollis, R Gehring, B J Bradford. Hot topic: Early postpartum treatment of commercial dairy cows with nonsteroidal antiinflammatory drugs increases whole-lactation milk yield.
Journal of dairy science.
2016 Jan; 99(1):672-9. doi:
10.3168/jds.2015-10048. [PMID: 26519977] - Orsolya Kinga Gondor, Magda Pál, Éva Darkó, Tibor Janda, Gabriella Szalai. Salicylic Acid and Sodium Salicylate Alleviate Cadmium Toxicity to Different Extents in Maize (Zea mays L.).
PloS one.
2016; 11(8):e0160157. doi:
10.1371/journal.pone.0160157. [PMID: 27490102] - Margareta Kračun-Kolarević, Slavica Dmitrović, Biljana Filipović, Marija Perić, Danijela Mišić, Ana Simonović, Slađana Todorović. Influence of sodium salicylate on rosmarinic acid, carnosol and carnosic acid accumulation by Salvia officinalis L. shoots grown in vitro.
Biotechnology letters.
2015 Aug; 37(8):1693-701. doi:
10.1007/s10529-015-1825-1. [PMID: 25836371] - Asie Shojaii, Manijeh Motevalian, Nazanin Rahnama. Evaluation of anti-inflammatory and analgesic activities and the phytochemical study of Astragalus arbusculinus gum in animal models.
Journal of basic and clinical physiology and pharmacology.
2015 Jul; 26(4):369-74. doi:
10.1515/jbcpp-2014-0092. [PMID: 25536664] - J Dey, S Kumar, V K Aswal, L V Panicker, K Ismail, P A Hassan. Effect of sodium salicylate and sodium deoxycholate on fibrillation of bovine serum albumin: comparison of fluorescence, SANS and DLS techniques.
Physical chemistry chemical physics : PCCP.
2015 Jun; 17(23):15442-51. doi:
10.1039/c5cp01666e. [PMID: 26006778] - Kerstin Cramer, Volker Schmidt, Andreas Richter, Herbert Fuhrmann, Getu Abraham, Maria-Elisabeth Krautwald-Junghanns. [Investigations on the acute, carrageenan-induced inflammatory reaction and pharmacology of orally administered sodium salicylate in turkeys].
Berliner und Munchener tierarztliche Wochenschrift.
2015 May; 128(5-6):240-51. doi:
. [PMID: 26054231] - Błażej Poźniak, Tomasz Grabowski, Karolina Motykiewicz-Pers, Kamila Bobrek, Lech Rak, Katarzyna Bobusia, Andrzej Gaweł, Marcin Świtała. Pharmacokinetics of repeated sodium salicylate administration to laying hens: evidence for time dependent increase in drug elimination from plasma and eggs.
PloS one.
2015; 10(4):e0123526. doi:
10.1371/journal.pone.0123526. [PMID: 25893240] - C Máthé, G Szénási, A Sebestény, A Blázovics, K Szentmihályi, P Hamar, M Albert. Protective effect of CV247 against cisplatin nephrotoxicity in rats.
Human & experimental toxicology.
2014 Aug; 33(8):789-99. doi:
10.1177/0960327113480972. [PMID: 23653282] - Louise Wassermann, Sandra Halwachs, Daniela Baumann, Ingo Schaefer, Peter Seibel, Walther Honscha. Assessment of ABCG2-mediated transport of xenobiotics across the blood-milk barrier of dairy animals using a new MDCKII in vitro model.
Archives of toxicology.
2013 Sep; 87(9):1671-82. doi:
10.1007/s00204-013-1066-9. [PMID: 23652544] - Jaymelynn K Farney, Laman K Mamedova, Johann F Coetzee, Butch KuKanich, Lorraine M Sordillo, Sara K Stoakes, J Ernest Minton, Larry C Hollis, Barry J Bradford. Anti-inflammatory salicylate treatment alters the metabolic adaptations to lactation in dairy cattle.
American journal of physiology. Regulatory, integrative and comparative physiology.
2013 Jul; 305(2):R110-7. doi:
10.1152/ajpregu.00152.2013. [PMID: 23678026] - Sandra Pereira, Wen Qin Yu, María E Frigolet, Jacqueline L Beaudry, Yaniv Shpilberg, Edward Park, Cristina Dirlea, B L Grégoire Nyomba, Michael C Riddell, I George Fantus, Adria Giacca. Duration of rise in free fatty acids determines salicylate's effect on hepatic insulin sensitivity.
The Journal of endocrinology.
2013 Apr; 217(1):31-43. doi:
10.1530/joe-12-0214. [PMID: 23328071] - P Thakur, B Nehru. Anti-inflammatory properties rather than anti-oxidant capability is the major mechanism of neuroprotection by sodium salicylate in a chronic rotenone model of Parkinson's disease.
Neuroscience.
2013 Feb; 231(?):420-31. doi:
10.1016/j.neuroscience.2012.11.006. [PMID: 23159314] - Itsuro Kazama, Yoshio Maruyama, Sara Takahashi, Takashi Kokumai. Amphipaths differentially modulate membrane surface deformation in rat peritoneal mast cells during exocytosis.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.
2013; 31(4-5):592-600. doi:
10.1159/000350079. [PMID: 23635874] - B Poźniak, M Świtała, K Jaworski, P Okoniewski, P Niewiński. Comparative pharmacokinetics of acetylsalicylic acid and sodium salicylate in chickens and turkeys.
British poultry science.
2013; 54(4):538-44. doi:
10.1080/00071668.2013.809403. [PMID: 23906222] - Itsuro Kazama, Yoshio Maruyama, Yoshimichi Murata. Suppressive effects of nonsteroidal anti-inflammatory drugs diclofenac sodium, salicylate and indomethacin on delayed rectifier K+-channel currents in murine thymocytes.
Immunopharmacology and immunotoxicology.
2012 Oct; 34(5):874-8. doi:
10.3109/08923973.2012.666249. [PMID: 22409730] - B Poźniak, M Switała, K Bobrek, S Graczyk, S Dzimira. Adverse effects associated with high-dose acetylsalicylic acid and sodium salicylate treatment in broilers.
British poultry science.
2012; 53(6):777-83. doi:
10.1080/00071668.2012.745929. [PMID: 23398422] - L Bergamasco, J F Coetzee, R Gehring, L Murray, T Song, R A Mosher. Effect of intravenous sodium salicylate administration prior to castration on plasma cortisol and electroencephalography parameters in calves.
Journal of veterinary pharmacology and therapeutics.
2011 Dec; 34(6):565-76. doi:
10.1111/j.1365-2885.2011.01269.x. [PMID: 21303378] - Sarah L Baldridge, Johann F Coetzee, Steve S Dritz, James B Reinbold, Ronette Gehring, James Havel, Butch Kukanich. Pharmacokinetics and physiologic effects of intramuscularly administered xylazine hydrochloride-ketamine hydrochloride-butorphanol tartrate alone or in combination with orally administered sodium salicylate on biomarkers of pain in Holstein calves following castration and dehorning.
American journal of veterinary research.
2011 Oct; 72(10):1305-17. doi:
10.2460/ajvr.72.10.1305. [PMID: 21962272] - William E Brownell, Stefan Jacob, Pierre Hakizimana, Mats Ulfendahl, Anders Fridberger. Membrane cholesterol modulates cochlear electromechanics.
Pflugers Archiv : European journal of physiology.
2011 Jun; 461(6):677-86. doi:
10.1007/s00424-011-0942-5. [PMID: 21373862] - Dianxiu Cao, Yuko Tazawa, Hiroshi Ishii, Hiroaki Todo, Kenji Sugibayashi. Pretreatment effects of moxibustion on the skin permeation and skin and muscle concentrations of salicylate in rats.
International journal of pharmaceutics.
2011 Apr; 407(1-2):105-10. doi:
10.1016/j.ijpharm.2011.01.026. [PMID: 21256938] - S de Boever, E A Neirinckx, E Meyer, S de Baere, R Beyaert, P de Backer, S Croubels. Pharmacodynamics of tepoxalin, sodium-salicylate and ketoprofen in an intravenous lipopolysaccharide inflammation model in broiler chickens.
Journal of veterinary pharmacology and therapeutics.
2010 Dec; 33(6):564-72. doi:
10.1111/j.1365-2885.2010.01184.x. [PMID: 21062309] - O V Drobins'ka, L M Gaĭda, K O Dvorshchenko, M O Tymoshenko, L I Ostapchenko. [The state of lipid peroxidation and antioxidant protection system in parietal cells under experimental chronic atrophic gastritis development].
Ukrains'kyi biokhimichnyi zhurnal (1999 ).
2010 Sep; 82(5):85-91. doi:
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Diabetes research and clinical practice.
2010 Aug; 89(2):150-6. doi:
10.1016/j.diabres.2010.04.004. [PMID: 20493573] - José Hélio Costa, Erika Freitas Mota, Mariana Virginia Cambursano, Martin Alexander Lauxmann, Luciana Maia Nogueira de Oliveira, Maria da Guia Silva Lima, Elena Graciela Orellano, Dirce Fernandes de Melo. Stress-induced co-expression of two alternative oxidase (VuAox1 and 2b) genes in Vigna unguiculata.
Journal of plant physiology.
2010 May; 167(7):561-70. doi:
10.1016/j.jplph.2009.11.001. [PMID: 20005596] - Bing He, Sheng Zhao, Wei Zhang, Yan Li, Ping Han. Effect of sodium salicylate on oxidative stress and insulin resistance induced by free fatty acids.
Hepatobiliary & pancreatic diseases international : HBPD INT.
2010 Feb; 9(1):49-53. doi:
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American journal of physiology. Endocrinology and metabolism.
2009 Nov; 297(5):E1205-11. doi:
10.1152/ajpendo.00313.2009. [PMID: 19755670] - Kristin Rule Gleitsman, Michihiro Tateyama, Yoshihiro Kubo. Structural rearrangements of the motor protein prestin revealed by fluorescence resonance energy transfer.
American journal of physiology. Cell physiology.
2009 Aug; 297(2):C290-8. doi:
10.1152/ajpcell.00647.2008. [PMID: 19515900] - J L Kotschwar, J F Coetzee, D E Anderson, R Gehring, B KuKanich, M D Apley. Analgesic efficacy of sodium salicylate in an amphotericin B-induced bovine synovitis-arthritis model.
Journal of dairy science.
2009 Aug; 92(8):3731-43. doi:
10.3168/jds.2009-2058. [PMID: 19620655] - R J Dinis-Oliveira, H Pontes, M L Bastos, F Remião, J A Duarte, F Carvalho. An effective antidote for paraquat poisonings: the treatment with lysine acetylsalicylate.
Toxicology.
2009 Jan; 255(3):187-93. doi:
10.1016/j.tox.2008.10.015. [PMID: 19026709] - E A Günter, O M Kapustina, O V Popeyko, T I Chelpanova, E A Efimtseva, Yu S Ovodov. Induction of beta-1,3-glucanase in callus cultures in vitro.
Biochemistry. Biokhimiia.
2008 Jul; 73(7):826-32. doi:
10.1134/s0006297908070110. [PMID: 18707591] - Edward Park, Victor Wong, Xinyu Guan, Andrei I Oprescu, Adria Giacca. Salicylate prevents hepatic insulin resistance caused by short-term elevation of free fatty acids in vivo.
The Journal of endocrinology.
2007 Nov; 195(2):323-31. doi:
10.1677/joe-07-0005. [PMID: 17951543] - Martin Philpott, Laura Mackay, Lynnette R Ferguson, Davanea Forbes, Margot Skinner. Cell culture models in developing nutrigenomics foods for inflammatory bowel disease.
Mutation research.
2007 Sep; 622(1-2):94-102. doi:
10.1016/j.mrfmmm.2007.04.013. [PMID: 17568627] - J F Coetzee, R Gehring, A C Bettenhausen, B V Lubbers, S E Toerber, D U Thomson, B Kukanich, M D Apley. Attenuation of acute plasma cortisol response in calves following intravenous sodium salicylate administration prior to castration.
Journal of veterinary pharmacology and therapeutics.
2007 Aug; 30(4):305-13. doi:
10.1111/j.1365-2885.2007.00869.x. [PMID: 17610403] - Man Zhi, J Tilak Ratnanather, Elvan Ceyhan, Aleksander S Popel, William E Brownell. Hypotonic swelling of salicylate-treated cochlear outer hair cells.
Hearing research.
2007 Jun; 228(1-2):95-104. doi:
10.1016/j.heares.2007.02.007. [PMID: 17400411] - Kenneth K Wu. Differential cyclooxygenase-2 transcriptional control in proliferating versus quiescent fibroblasts.
Prostaglandins & other lipid mediators.
2007 May; 83(3):175-81. doi:
10.1016/j.prostaglandins.2007.01.002. [PMID: 17481552] - Xu Wang, Hui Chen, Jin-Ming Lin, Xitang Ying. Development of a highly sensitive and selective microplate chemiluminescence enzyme immunoassay for the determination of free thyroxine in human serum.
International journal of biological sciences.
2007 Apr; 3(5):274-80. doi:
10.7150/ijbs.3.274. [PMID: 17505537] - R J Dinis-Oliveira, C Sousa, F Remião, J A Duarte, A Sánchez Navarro, M L Bastos, F Carvalho. Full survival of paraquat-exposed rats after treatment with sodium salicylate.
Free radical biology & medicine.
2007 Apr; 42(7):1017-28. doi:
10.1016/j.freeradbiomed.2006.12.031. [PMID: 17349929] - Dana L Shuey, Ramadevi Gudi, Ljubica Krsmanovic, Ronald J Gerson. Evidence that oxymorphone-induced increases in micronuclei occur secondary to hyperthermia.
Toxicological sciences : an official journal of the Society of Toxicology.
2007 Feb; 95(2):369-75. doi:
10.1093/toxsci/kfl148. [PMID: 17077185] - Caroline M Forrest, Gillian M Mackay, Lynn Oxford, Nicholas Stoy, Trevor W Stone, L Gail Darlington. Kynurenine pathway metabolism in patients with osteoporosis after 2 years of drug treatment.
Clinical and experimental pharmacology & physiology.
2006 Nov; 33(11):1078-87. doi:
10.1111/j.1440-1681.2006.04490.x. [PMID: 17042918] - Sapar M Saparov, Yuri N Antonenko, Peter Pohl. A new model of weak acid permeation through membranes revisited: does Overton still rule?.
Biophysical journal.
2006 Jun; 90(11):L86-8. doi:
10.1529/biophysj.106.084343. [PMID: 16603491] - Omran M O Alhamami, Najah H Aljanabi, Naeem M Shalan. Biopharmaceutic and pharmacokinetic studies following the oral administration of sodium salicylate in oily and aqueous vehicles to rabbit.
International journal of pharmaceutics.
2006 Mar; 311(1-2):63-8. doi:
10.1016/j.ijpharm.2005.12.011. [PMID: 16455214] - Timothy D Warner, Ivana Vojnovic, David Bishop-Bailey, Jane A Mitchell. Influence of plasma protein on the potencies of inhibitors of cyclooxygenase-1 and -2.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2006 Mar; 20(3):542-4. doi:
10.1096/fj.05-4434fje. [PMID: 16403783] - F Paul Silverman, Peter D Petracek, Daniel F Heiman, Zhiguo Ju, Christina M Fledderman, Prem Warrior. Salicylate activity. 2. Potentiation of atrazine.
Journal of agricultural and food chemistry.
2005 Dec; 53(25):9769-74. doi:
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Journal of agricultural and food chemistry.
2005 Dec; 53(25):9764-8. doi:
10.1021/jf0513819. [PMID: 16332128] - Huma Rashid, Mohammad Mushahid Khan, Saad Tayyab. Interaction of bilirubin with sealed and human serum albumin-entrapped sealed membranes.
Molecular and cellular biochemistry.
2005 Sep; 277(1-2):101-7. doi:
10.1007/s11010-005-5425-6. [PMID: 16132720] - K Baert, L Duchateau, S De Boever, M Cherlet, P De Backer. Antipyretic effect of oral sodium salicylate after an intravenous E. coli LPS injection in broiler chickens.
British poultry science.
2005 Apr; 46(2):137-43. doi:
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Journal of veterinary pharmacology and therapeutics.
2004 Apr; 27(2):123-7. doi:
10.1111/j.1365-2885.2004.00554.x. [PMID: 15096112] - Stefaan Vervarcke, Frans Ollevier, Renaat Kinget, Armand Michoel. Oral vaccination of African catfish with Vibrio anguillarum O2: effect on antigen uptake and immune response by absorption enhancers in lag time coated pellets.
Fish & shellfish immunology.
2004 Mar; 16(3):407-14. doi:
10.1016/j.fsi.2003.07.002. [PMID: 15123307] - David M Aronoff, Olivier Boutaud, Lawrence J Marnett, John A Oates. Inhibition of prostaglandin H2 synthases by salicylate is dependent on the oxidative state of the enzymes.
The Journal of pharmacology and experimental therapeutics.
2003 Feb; 304(2):589-95. doi:
10.1124/jpet.102.042853. [PMID: 12538810] - Pingsheng Ji, Mark Wilson. Enhancement of population size of a biological control agent and efficacy in control of bacterial speck of tomato through salicylate and ammonium sulfate amendments.
Applied and environmental microbiology.
2003 Feb; 69(2):1290-4. doi:
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Kidney international.
2003 Jan; 63(1):143-55. doi:
10.1046/j.1523-1755.2003.00710.x. [PMID: 12472777] - K Baert, P De Backer. Comparative pharmacokinetics of three non-steroidal anti-inflammatory drugs in five bird species.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.
2003 Jan; 134(1):25-33. doi:
10.1016/s1532-0456(02)00184-9. [PMID: 12524015] - K Baert, P De Backer. Disposition of sodium salicylate, flunixin and meloxicam after intravenous administration in broiler chickens.
Journal of veterinary pharmacology and therapeutics.
2002 Dec; 25(6):449-53. doi:
10.1046/j.1365-2885.2002.00441.x. [PMID: 12485350] - Phuong Oanh T Tran, Catherine E Gleason, R Paul Robertson. Inhibition of interleukin-1beta-induced COX-2 and EP3 gene expression by sodium salicylate enhances pancreatic islet beta-cell function.
Diabetes.
2002 Jun; 51(6):1772-8. doi:
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Drug development and industrial pharmacy.
2002 May; 28(5):563-70. doi:
10.1081/ddc-120003452. [PMID: 12098845] - Ehab A Hosny, Hassan I Al-Shora, Mohamed M A Elmazar. Oral delivery of insulin from enteric-coated capsules containing sodium salicylate: effect on relative hypoglycemia of diabetic beagle dogs.
International journal of pharmaceutics.
2002 Apr; 237(1-2):71-6. doi:
10.1016/s0378-5173(02)00024-8. [PMID: 11955805] - Toshio Obata, Yasumitsu Yamanaka. Iron (III) attenuates hydroxyl radical generation accompanying non-enzymatic oxidation of noradrenaline in the rat heart.
Naunyn-Schmiedeberg's archives of pharmacology.
2002 Feb; 365(2):158-63. doi:
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Bollettino chimico farmaceutico.
2002 Jan; 141(1):67-74. doi:
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Biological & pharmaceutical bulletin.
2001 Nov; 24(11):1294-7. doi:
10.1248/bpb.24.1294. [PMID: 11725967] - M A Saunders, L Sansores-Garcia, D W Gilroy, K K Wu. Selective suppression of CCAAT/enhancer-binding protein beta binding and cyclooxygenase-2 promoter activity by sodium salicylate in quiescent human fibroblasts.
The Journal of biological chemistry.
2001 Jun; 276(22):18897-904. doi:
10.1074/jbc.m011147200. [PMID: 11278846] - D Wu, A I Cederbaum. Sodium salicylate increases CYP2E1 levels and enhances arachidonic acid toxicity in HepG2 cells and cultured rat hepatocytes.
Molecular pharmacology.
2001 Apr; 59(4):795-805. doi:
10.1124/mol.59.4.795. [PMID: 11259624] - L Levine. A combination of lactacystin and 12-O-tetradecanoylphorbol-13-acetate enhances the release of arachidonic acid from cells in cultures: release is reduced in confluent and serum deprived cells.
Prostaglandins, leukotrienes, and essential fatty acids.
2000 Dec; 63(6):363-70. doi:
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Mikrobiologiia.
2000 Nov; 69(6):844-9. doi:
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Circulation.
2000 Oct; 102(17):2124-30. doi:
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Toxicology in vitro : an international journal published in association with BIBRA.
2000 Aug; 14(4):297-307. doi:
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Nature.
2000 May; 405(6783):149-55. doi:
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Hypertension (Dallas, Tex. : 1979).
2000 May; 35(5):1085-91. doi:
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The Journal of biological chemistry.
1999 Dec; 274(50):35630-8. doi:
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European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
1999 Dec; 9(2):137-43. doi:
10.1016/s0928-0987(99)00055-x. [PMID: 10620726] - A Kagawa, H Azuma, M Akaike, Y Kanagawa, T Matsumoto. Aspirin reduces apolipoprotein(a) (apo(a)) production in human hepatocytes by suppression of apo(a) gene transcription.
The Journal of biological chemistry.
1999 Nov; 274(48):34111-5. doi:
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International journal of pharmaceutics.
1999 Nov; 189(2):137-45. doi:
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Pharmacology & toxicology.
1999 Nov; 85(5):206-11. doi:
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Free radical biology & medicine.
1999 Aug; 27(3-4):428-37. doi:
10.1016/s0891-5849(99)00075-1. [PMID: 10468218] - R S Luo, M L Liu, X A Mao. NMR diffusion and relaxation study of drug-protein interaction.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
1999 Aug; 55A(9):1897-901. doi:
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The Journal of surgical research.
1999 May; 83(1):56-61. doi:
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Proceedings of the National Academy of Sciences of the United States of America.
1999 Apr; 96(9):5292-7. doi:
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Plant molecular biology.
1999 Apr; 39(6):1137-51. doi:
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General pharmacology.
1998 Sep; 31(3):405-8. doi:
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Indian journal of experimental biology.
1998 Jul; 36(7):651-7. doi:
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Pharmaceutical research.
1998 Jul; 15(7):1019-25. doi:
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Free radical biology & medicine.
1998 Jul; 25(1):87-94. doi:
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