Tetraprenol (BioDeep_00000007165)

 

Secondary id: BioDeep_00000175571, BioDeep_00000638555, BioDeep_00000872044

PANOMIX_OTCML-2023


代谢物信息卡片


2,6,10,14-Hexadecatetraen-1-ol, 3,7,11,15-tetramethyl-, (2E,6E,10E)- (9CI)

化学式: C20H34O (290.261)
中文名称: ALL TRANS-3,7,11-15-四甲基-2,6,10,14-十六烷四烯-1-醇, 香叶基香叶醇, 全氟聚醚基表面活性剂
谱图信息: 最多检出来源 Viridiplantae(plant) 9.78%

分子结构信息

SMILES: C/C(C)=C\CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CO
InChI: InChI=1S/C20H34O/c1-17(2)9-6-10-18(3)11-7-12-19(4)13-8-14-20(5)15-16-21/h9,11,13,15,21H,6-8,10,12,14,16H2,1-5H3/b18-11+,19-13+,20-15+

描述信息

Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model[1][2][3][4].
Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model[1][2][3][4].

同义名列表

29 个代谢物同义名

2,6,10,14-Hexadecatetraen-1-ol, 3,7,11,15-tetramethyl-, (2E,6E,10E)- (9CI); 2,6,10,14-Hexadecatetraen-1-ol, 3,7,11,15-tetramethyl-, (E,E,E)- (8CI); (2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-ol; all trans-3,7,11-15-Tetramethyl-2,6,10,14-hexadecatetraen-1-ol; 2,6,10,14-Hexadecatetraen-1-ol, 3,7,11,15-tetramethyl-; 3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-ol; trans,trans,trans-Geranylgeraniol; All-trans-Geranylgeraniol; (e,e,e)-geranylgeraniol; trans-Geranylgeraniol; Spectrum5_002040; NCGC00096069-01; SPECTRUM1505009; NCGC00096069-02; GERANYLGERANIOL; Gernaylgeraniol; FLUOROLINK(R) D; CHEBI:46762; Tetraprenol; CHEBI:24229; G3278_SIGMA; 24034-73-9; 7614-21-3; C09094; 3,7,11,15-tetramethylhexadeca-2E,6E,10E,14-tetraen-1-ol; (E,E,E)-Geranylgeranyl alcohol; Geranyl geraniol; Geranylgeraniol; Geranylgeraniol



数据库引用编号

22 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(1)

代谢反应

2 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(1)

  • plaunotol biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + geranylgeraniol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + plaunotol

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(1)

  • plaunotol biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + geranylgeraniol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + plaunotol

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

13 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 13 AKT1, ANG, BCL2, CASP3, CASP9, FNTA, GGPS1, MAPK8, MVK, RAC1, RAP1A, RHOA, VEGFA
Endosome membrane 1 RAP1A
Endoplasmic reticulum membrane 4 BCL2, HMGCR, RAC1, RHOA
Nucleus 9 AKT1, ANG, BCL2, CASP3, CASP9, MAPK8, RAC1, RHOA, VEGFA
cytosol 12 AKT1, ANG, BCL2, CASP3, CASP9, FNTA, GGPS1, MAPK8, MVK, RAC1, RAP1A, RHOA
dendrite 1 RAC1
trans-Golgi network 1 RAC1
nucleoplasm 4 AKT1, CASP3, GGPS1, MAPK8
Cell membrane 5 AKT1, RAC1, RAP1A, RHOA, TNF
Lipid-anchor 3 RAC1, RAP1A, RHOA
Cytoplasmic side 2 RAC1, RHOA
Cleavage furrow 1 RHOA
lamellipodium 3 AKT1, RAC1, RHOA
ruffle membrane 2 RAC1, RHOA
Multi-pass membrane protein 1 HMGCR
Synapse 2 MAPK8, RAC1
cell cortex 3 AKT1, RAC1, RHOA
cell junction 2 RAP1A, RHOA
cell surface 2 TNF, VEGFA
glutamatergic synapse 5 AKT1, CASP3, RAC1, RAP1A, RHOA
Golgi apparatus 1 VEGFA
Golgi membrane 1 INS
growth cone 1 ANG
neuronal cell body 3 ANG, CASP3, TNF
postsynapse 3 AKT1, RAC1, RHOA
Presynapse 1 RAP1A
endosome 1 RHOA
plasma membrane 6 AKT1, FNTA, RAC1, RAP1A, RHOA, TNF
Membrane 5 AKT1, BCL2, HMGCR, RAC1, VEGFA
axon 1 MAPK8
extracellular exosome 4 BMP3, RAC1, RAP1A, RHOA
endoplasmic reticulum 3 BCL2, HMGCR, VEGFA
extracellular space 7 ANG, BMP3, CCL2, IL6, INS, TNF, VEGFA
guanyl-nucleotide exchange factor complex 1 RAP1A
perinuclear region of cytoplasm 2 GGPS1, RAP1A
adherens junction 1 VEGFA
mitochondrion 2 BCL2, CASP9
protein-containing complex 3 AKT1, BCL2, CASP9
intracellular membrane-bounded organelle 1 MVK
postsynaptic density 1 CASP3
Secreted 7 ANG, BMP3, CCL2, IL6, INS, RAC1, VEGFA
extracellular region 8 ANG, BMP3, CCL2, IL6, INS, RAC1, TNF, VEGFA
cytoplasmic side of plasma membrane 1 RHOA
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 1 BCL2
anchoring junction 1 RAP1A
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 1 TNF
Secreted, extracellular space, extracellular matrix 1 VEGFA
actin cytoskeleton 1 ANG
dendritic spine 2 RAC1, RHOA
Z disc 1 GGPS1
cytoplasmic vesicle 1 RAC1
microtubule cytoskeleton 1 AKT1
nucleolus 1 ANG
midbody 1 RHOA
Early endosome 1 RAP1A
cell-cell junction 1 AKT1
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
vesicle 2 AKT1, RHOA
Cell projection, lamellipodium 2 RAC1, RHOA
Cytoplasm, perinuclear region 2 GGPS1, RAP1A
Membrane raft 1 TNF
pore complex 1 BCL2
focal adhesion 2 RAC1, RHOA
spindle 1 AKT1
extracellular matrix 1 VEGFA
Peroxisome 1 MVK
basement membrane 1 ANG
peroxisomal membrane 1 HMGCR
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
secretory granule 1 VEGFA
Late endosome 1 RAP1A
neuron projection 1 RAP1A
ciliary basal body 1 AKT1
microtubule associated complex 1 FNTA
phagocytic cup 1 TNF
cell periphery 1 RHOA
Chromosome 1 ANG
cytoskeleton 2 RAC1, RHOA
cytoplasmic ribonucleoprotein granule 1 RAC1
Nucleus, nucleolus 1 ANG
Cytoplasm, cell cortex 1 RHOA
sperm midpiece 1 RAP1A
Recycling endosome membrane 1 RAC1
Endomembrane system 1 RAP1A
endosome lumen 1 INS
Cell projection, dendrite 2 RAC1, RHOA
specific granule membrane 1 RAP1A
Melanosome 1 RAC1
Cytoplasm, Stress granule 1 ANG
cytoplasmic stress granule 1 ANG
myelin sheath 1 BCL2
Peroxisome membrane 1 HMGCR
Cytoplasm, myofibril, sarcomere, Z line 1 GGPS1
secretory granule lumen 1 INS
secretory granule membrane 2 RAC1, RHOA
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 IL6, INS
platelet alpha granule lumen 1 VEGFA
endocytic vesicle 1 ANG
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
apoptosome 1 CASP9
ficolin-1-rich granule membrane 2 RAC1, RHOA
basal dendrite 1 MAPK8
death-inducing signaling complex 1 CASP3
apical junction complex 1 RHOA
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
angiogenin-PRI complex 1 ANG
NADPH oxidase complex 1 RAC1
interleukin-6 receptor complex 1 IL6
BAD-BCL-2 complex 1 BCL2
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
CAAX-protein geranylgeranyltransferase complex 2 FNTA, PGGT1B
protein farnesyltransferase complex 1 FNTA
caspase complex 1 CASP9
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


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