Methylprednisolone acetate (BioDeep_00000006678)
代谢物信息卡片
6α-METHYLPREDNISOLONE ACETATE
化学式: C24H32O6 (416.2198772)
中文名称: 6α-甲基泼尼松龙21-乙酸盐
谱图信息:
最多检出来源 Viridiplantae(plant) 66.67%
分子结构信息
SMILES: CC(=O)OCC(=O)C1(O)CCC2C3CC(C)C4=CC(=O)C=CC4(C)C3C(O)CC21C
InChI: InChI=1S/C24H32O6/c1-13-9-16-17-6-8-24(29,20(28)12-30-14(2)25)23(17,4)11-19(27)21(16)22(3)7-5-15(26)10-18(13)22/h5,7,10,13,16-17,19,21,27,29H,6,8-9,11-12H2,1-4H3/t13-,16-,17-,19-,21+,22-,23-,24-/m0/s1
描述信息
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid
D000893 - Anti-Inflammatory Agents
同义名列表
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:6889
- KEGG: C08179
- KEGGdrug: D00979
- KEGGdrug: D87728
- PubChem: 5877
- Metlin: METLIN43896
- ChEMBL: CHEMBL1364144
- MeSH: Methylprednisolone Acetate
- CAS: 53-36-1
- PMhub: MS000019757
- PubChem: 10379
- NIKKAJI: J4.144K
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- I Koca, M Ucar, H O Arik, M Yilmaz, R Dokuyucu. Alpha-lipoic acid could be a promising treatment in steroid-induced osteonecrosis.
European review for medical and pharmacological sciences.
2022 10; 26(20):7404-7412. doi:
10.26355/eurrev_202210_30009. [PMID: 36314310] - Karine Marchioro Leal, Mariana Barcelos Rocha, Fernanda Venzon Varela, Luana Rodrigues, Priscila Viau Furtado, Fernanda Vieira Amorim da Costa, Álan Gomes Pöppl. Is Methylprednisolone Acetate-Related Insulin Resistance Preventable in Cats?.
Topics in companion animal medicine.
2022 Jul; 49(?):100648. doi:
10.1016/j.tcam.2022.100648. [PMID: 35202848] - Esther M Millares-Ramirez, Khristine Picotte, Jean-Pierre Lavoie. Pulmonary response of severely asthmatic horses after intra-articular administration of methylprednisolone.
Equine veterinary journal.
2021 Jan; 53(1):78-84. doi:
10.1111/evj.13272. [PMID: 32348605] - Aydın Yıldız, Müşerref Hilal Şehitoğlu, İhsan Karaboğa, Sedat Arıkan. Ozone treatment for high-dose systemic Steroid-Induced retinal injury.
Cutaneous and ocular toxicology.
2020 Sep; 39(3):274-280. doi:
10.1080/15569527.2020.1790590. [PMID: 32619116] - Laura Hrehová, Kamal Mezian, Levent Özçakar. Ultrasonographic approach for a foot ganglion after sewing masks in the COVID-19 pandemic: Blessing in disguise.
Work (Reading, Mass.).
2020; 67(4):763-765. doi:
10.3233/wor-203328. [PMID: 33325426] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Zheng Ding, Huifeng Shi, Wei Yang. Osteoprotective Effect of Cimiracemate in Glucocorticoid-Induced Osteoporosis by Osteoprotegerin/Receptor Activator of Nuclear Factor κ B/Receptor Activator of Nuclear Factor Kappa-Β Ligand Signaling.
Pharmacology.
2019; 103(3-4):163-172. doi:
10.1159/000495509. [PMID: 30695776] - Rasha R Radwan, Heba A Mohamed, H E Ali, Ghada A Mahmoud. Radiation preparation of L-arginine/acrylic acid hydrogel matrix patch for transdermal delivery of propranolol HCl in hypertensive rats.
Drug delivery and translational research.
2018 06; 8(3):525-535. doi:
10.1007/s13346-017-0468-2. [PMID: 29313295] - Aleem Jameel Abdul, Babita Ghai, Dipika Bansal, Naresh Sachdeva, Anil Bhansali, Saravdeep Singh Dhatt. Hypothalamic Pituitary Adrenocortical Axis Suppression following a Single Epidural Injection of Methylprednisolone Acetate.
Pain physician.
2017 11; 20(7):E991-E1001. doi:
. [PMID: 29149147] - Hong-Xing Zhao, Yuan-Xia Huang, Jin-Gang Tao. ST1926 Attenuates Steroid-Induced Osteoporosis in Rats by Inhibiting Inflammation Response.
Journal of cellular biochemistry.
2017 08; 118(8):2072-2086. doi:
10.1002/jcb.25812. [PMID: 27918081] - Anders Ploug Boesen, Rudi Hansen, Morten Ilum Boesen, Peter Malliaras, Henning Langberg. Effect of High-Volume Injection, Platelet-Rich Plasma, and Sham Treatment in Chronic Midportion Achilles Tendinopathy: A Randomized Double-Blinded Prospective Study.
The American journal of sports medicine.
2017 Jul; 45(9):2034-2043. doi:
10.1177/0363546517702862. [PMID: 28530451] - George Habib, Shada Elias, Muhanned Abu-Elhaija, Fahed Sakas, Fadi Khazin, Suheil Artul, Adel Jabbour, Haneen Jabaly-Habib. The effect of local injection of methylprednisolone acetate on the hypothalamic-pituitary-adrenal axis among patients with greater trochanteric pain syndrome.
Clinical rheumatology.
2017 Apr; 36(4):959-963. doi:
10.1007/s10067-016-3517-1. [PMID: 28013434] - Jia-Guo Zhao, Jia Wang, Wan-Jie Huang, Peng Zhang, Ning Ding, Jian Shang. Interventions for treating simple bone cysts in the long bones of children.
The Cochrane database of systematic reviews.
2017 02; 2(?):CD010847. doi:
10.1002/14651858.cd010847.pub3. [PMID: 28158933] - Bijan Forogh, Elaheh Mianehsaz, Shervan Shoaee, Tannaz Ahadi, Gholam R Raissi, Simin Sajadi. Effect of single injection of platelet-rich plasma in comparison with corticosteroid on knee osteoarthritis: a double-blind randomized clinical trial.
The Journal of sports medicine and physical fitness.
2016 Jul; 56(7-8):901-8. doi:
NULL. [PMID: 26173792] - George Habib, Fahed Sakas, Suheil Artul, Fadi Khazin, Geries Hakim, Adel Jabbour, Haneen Jabaly-Habib. The impact of intra-articular methylprednisolone acetate injection on fructosamine levels in diabetic patients with osteoarthritis of the knee, a case-control study.
Clinical rheumatology.
2016 Jun; 35(6):1609-14. doi:
10.1007/s10067-016-3218-9. [PMID: 26951257] - M L Dever, L P Kahn, E K Doyle, S W Walkden-Brown. Immune-mediated responses account for the majority of production loss for grazing meat-breed lambs during Trichostrongylus colubriformis infection.
Veterinary parasitology.
2016 Jan; 216(?):23-32. doi:
10.1016/j.vetpar.2015.11.017. [PMID: 26801591] - Karan Agrawal, Joseph G Ebel, Karyn Bischoff. A rapid screen for four corticosteroids in equine synovial fluid.
Journal of analytical toxicology.
2014 Jun; 38(5):272-9. doi:
10.1093/jat/bku030. [PMID: 24713534] - Jian-Ping Li, Sen Chen, Hao Peng, Jian-Lin Zhou, Hong-Song Fang. Pulsed electromagnetic fields protect the balance between adipogenesis and osteogenesis on steroid-induced osteonecrosis of femoral head at the pre-collapse stage in rats.
Bioelectromagnetics.
2014 Apr; 35(3):170-80. doi:
10.1002/bem.21833. [PMID: 24421074] - H K Knych, L M Harrison, H C Casbeer, D S McKemie. Disposition of methylprednisolone acetate in plasma, urine, and synovial fluid following intra-articular administration to exercised thoroughbred horses.
Journal of veterinary pharmacology and therapeutics.
2014 Apr; 37(2):125-32. doi:
10.1111/jvp.12070. [PMID: 23876165] - George Habib, Fadi Khazin, Adel Jabbour, Mark Chernin, Samih Badarny, Jeries Hakim, Suheil Artul. Simultaneous bilateral knee injection of methylprednisolone acetate and the hypothalamic-pituitary adrenal axis: a single-blind case-control study.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research.
2014 Mar; 62(3):621-6. doi:
10.2310/jim.0000000000000048. [PMID: 24430212] - George Habib, Adel Jabbour, Suheil Artul, Geries Hakim. Intra-articular methylprednisolone acetate injection at the knee joint and the hypothalamic-pituitary-adrenal axis: a randomized controlled study.
Clinical rheumatology.
2014 Jan; 33(1):99-103. doi:
10.1007/s10067-013-2374-4. [PMID: 23982564] - George Habib, Adel Jabbour, Jameel Salman, Geries Hakim, Henry Haddad. The effect of epidural methylprednisolone acetate injection on the hypothalamic-pituitary-adrenal axis.
Journal of clinical anesthesia.
2013 Dec; 25(8):629-33. doi:
10.1016/j.jclinane.2013.07.002. [PMID: 23988802] - Garida Zhao, Takuaki Yamamoto, Goro Motomura, Ryosuke Yamaguchi, Satoshi Ikemura, Kenyu Iwasaki, Yukihide Iwamoto. Cholesterol- and lanolin-rich diets may protect against steroid-induced osteonecrosis in rabbits.
Acta orthopaedica.
2013 Dec; 84(6):593-7. doi:
10.3109/17453674.2013.859421. [PMID: 24171681] - Gregory M Gauthier, Nancy P Keller. Crossover fungal pathogens: the biology and pathogenesis of fungi capable of crossing kingdoms to infect plants and humans.
Fungal genetics and biology : FG & B.
2013 Dec; 61(?):146-57. doi:
10.1016/j.fgb.2013.08.016. [PMID: 24021881] - Thomas M Kerkering, Marissa L Grifasi, Anthony W Baffoe-Bonnie, Ekta Bansal, Dorothy C Garner, Jean A Smith, Deborah D Demicco, Charles J Schleupner, Rabia A Aldoghaither, Vipul A Savaliya. Early clinical observations in prospectively followed patients with fungal meningitis related to contaminated epidural steroid injections.
Annals of internal medicine.
2013 Feb; 158(3):154-61. doi:
10.7326/0003-4819-158-3-201302050-00568. [PMID: 23183583] - Maria I Menéndez, Mitch A Phelps, Elijah A Hothem, Alicia L Bertone. Pharmacokinetics of methylprednisolone acetate after intra-articular administration and subsequent suppression of endogenous hydrocortisone secretion in exercising horses.
American journal of veterinary research.
2012 Sep; 73(9):1453-61. doi:
10.2460/ajvr.73.9.1453. [PMID: 22924728] - Christen Kirk Axelsson, Gro Maria Quamme, Charlotte Lanng, Pal Bela Szecsi, Minea Brusgaard Mortensen, Birgitte Wegeberg, Magnus Arpi, Marianne Lingskov, Mette Stub Puglich, Mette Okholm. Local injection of methylprednisolonacetat to prevent seroma formation after mastectomy.
Danish medical journal.
2012 Sep; 59(9):A4482. doi:
NULL. [PMID: 22951193] - Bang-Bao Lu, Kang-Hua Li. Lipoic acid prevents steroid-induced osteonecrosis in rabbits.
Rheumatology international.
2012 Jun; 32(6):1679-83. doi:
10.1007/s00296-011-1846-6. [PMID: 21431293] - Yoshihiro Nozaki, Kenji Kumagai, Noriaki Miyata, Masami Niwa. Pravastatin reduces steroid-induced osteonecrosis of the femoral head in SHRSP rats.
Acta orthopaedica.
2012 Feb; 83(1):87-92. doi:
10.3109/17453674.2011.641103. [PMID: 22313369] - Shuai Ding, Hao Peng, Hong-Song Fang, Jian-Lin Zhou, Zhe Wang. Pulsed electromagnetic fields stimulation prevents steroid-induced osteonecrosis in rats.
BMC musculoskeletal disorders.
2011 Sep; 12(?):215. doi:
10.1186/1471-2474-12-215. [PMID: 21958301] - N D Sargison, F Jackson, J S Gilleard. Effects of age and immune suppression of sheep on fecundity, hatching and larval feeding of different strains of Haemonchus contortus.
Veterinary journal (London, England : 1997).
2011 Sep; 189(3):296-301. doi:
10.1016/j.tvjl.2010.08.001. [PMID: 20822936] - Alessia Panusa, Luca Regazzoni, Giancarlo Aldini, Marica Orioli, Arrigo Giombini, Paola Minghetti, Carlo Tranquilli, Marina Carini. Urinary profile of methylprednisolone acetate metabolites in patients following intra-articular and intramuscular administration.
Analytical and bioanalytical chemistry.
2011 Apr; 400(1):255-67. doi:
10.1007/s00216-011-4744-6. [PMID: 21336796] - Alessia Panusa, Giancarlo Aldini, Marica Orioli, Giulio Vistoli, Giuseppe Rossoni, Marina Carini. A sensitive and specific precursor ion scanning approach in liquid chromatography/electrospray ionization tandem mass spectrometry to detect methylprednisolone acetate and its metabolites in rat urine.
Rapid communications in mass spectrometry : RCM.
2010 Jun; 24(11):1583-94. doi:
10.1002/rcm.4555. [PMID: 20486254] - Yurdal Serarslan, Zafer Yönden, Erkin Ozgiray, Süleyman Oktar, Eşref Oğuz Güven, Sadik Söğüt, Nebi Yilmaz, Taşkin Yurtseven. Protective effects of tadalafil on experimental spinal cord injury in rats.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia.
2010 Mar; 17(3):349-52. doi:
10.1016/j.jocn.2009.03.036. [PMID: 19875292] - Elaine R Garvican, Anne Vaughan-Thomas, Colette Redmond, Natalie Gabriel, Peter D Clegg. MMP-mediated collagen breakdown induced by activated protein C in equine cartilage is reduced by corticosteroids.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
2010 Mar; 28(3):370-8. doi:
10.1002/jor.21001. [PMID: 19777546] - Alessia Panusa, Marica Orioli, Giancarlo Aldini, Marina Carini. A rapid and sensitive LC-ESI-MS/MS method for detection and quantitation of methylprednisolone and methylprednisolone acetate in rat plasma after intra-articular administration.
Journal of pharmaceutical and biomedical analysis.
2010 Feb; 51(3):691-7. doi:
10.1016/j.jpba.2009.09.041. [PMID: 19875262] - Noriaki Miyata, Kenji Kumagai, Makoto Osaki, Masakazu Murata, Masato Tomita, Akira Hozumi, Yoshihiro Nozaki, Masami Niwa. Pentosan reduces osteonecrosis of femoral head in SHRSP.
Clinical and experimental hypertension (New York, N.Y. : 1993).
2010; 32(8):511-6. doi:
10.3109/10641963.2010.496511. [PMID: 21091356] - Goro Motomura, Takuaki Yamamoto, Keita Miyanishi, Kyoko Kondo, Yoshio Hirota, Yukihide Iwamoto. Risk factors for developing osteonecrosis after prophylaxis in steroid-treated rabbits.
The Journal of rheumatology.
2008 Dec; 35(12):2391-4. doi:
10.3899/jrheum.080416. [PMID: 19004034] - Kang Pengde, Pei Fuxing, Shen Bin, Yang Jing, Cheng Jingqiu. Lovastatin inhibits adipogenesis and prevents osteonecrosis in steroid-treated rabbits.
Joint bone spine.
2008 Dec; 75(6):696-701. doi:
10.1016/j.jbspin.2007.12.008. [PMID: 18620886] - Thomas A Miller, Frank W Schaefer. Methylprednisolone acetate immune suppression produces differing effects on Cryptosporidium muris oocyst production depending on when administered.
Veterinary parasitology.
2007 Oct; 149(1-2):77-84. doi:
10.1016/j.vetpar.2007.07.005. [PMID: 17719178] - Peng-de Kang, Bin Shen, Jing Yang, Hong-sheng Dang, Fu-xing Pei. [Platelet and endothelial cell-derived microparticles in steroid-induced osteonecrosis of the femoral head of rabbit model].
Zhonghua yi xue za zhi.
2007 Aug; 87(29):2045-9. doi:
. [PMID: 17925176] - Leslie C Sharkey, Trasida Ployngam, Anthony H Tobias, Sheila M F Torres. Effects of a single injection of methylprednisolone acetate on serum biochemical parameters in 11 cats.
Veterinary clinical pathology.
2007 Jun; 36(2):184-7. doi:
10.1111/j.1939-165x.2007.tb00206.x. [PMID: 17523093] - Lawrence R Soma, Cornelius E Uboh, Yi Luo, Fuyu Guan, Peter J Moate, Ray C Boston. Pharmacokinetics of methylprednisolone acetate after intra-articular administration and its effect on endogenous hydrocortisone and cortisone secretion in horses.
American journal of veterinary research.
2006 Apr; 67(4):654-62. doi:
10.2460/ajvr.67.4.654. [PMID: 16579759] - Trasida Ployngam, Anthony H Tobias, Stephanie A Smith, Sheila M F Torres, Sheri J Ross. Hemodynamic effects of methylprednisolone acetate administration in cats.
American journal of veterinary research.
2006 Apr; 67(4):583-7. doi:
10.2460/ajvr.67.4.583. [PMID: 16579749] - K Miyanishi, T Yamamoto, T Irisa, G Motomura, S Jingushi, K Sueishi, Y Iwamoto. Effects of different corticosteroids on the development of osteonecrosis in rabbits.
Rheumatology (Oxford, England).
2005 Mar; 44(3):332-6. doi:
10.1093/rheumatology/keh505. [PMID: 15598709] - S Martínez-Subiela, P J Ginel, J J Cerón. Effects of different glucocorticoid treatments on serum acute phase proteins in dogs.
The Veterinary record.
2004 Jun; 154(26):814-7. doi:
10.1136/vr.154.26.814. [PMID: 15260442] - A V Scorza, M M Brewer, M R Lappin. Polymerase chain reaction for the detection of Cryptosporidium spp. in cat feces.
The Journal of parasitology.
2003 Apr; 89(2):423-6. doi:
10.1645/0022-3395(2003)089[0423:pcrftd]2.0.co;2. [PMID: 12760674] - P J Ginel, R Lucena, M Fernández. Duration of increased serum alkaline phosphatase activity in dogs receiving different glucocorticoid doses.
Research in veterinary science.
2002 Jun; 72(3):201-4. doi:
10.1053/rvsc.2001.0541. [PMID: 12076114] - Stephanie A Smith, Lisa C Freeman, Mary Bagladi-Swanson. Hypercalcemia due to latrogenic secondary hypoadrenocorticism and diabetes mellitus in a cat.
Journal of the American Animal Hospital Association.
2002 Jan; 38(1):41-4. doi:
10.5326/0380041. [PMID: 11804313] - L Ferasin. Iatrogenic hyperadrenocorticism in a cat following a short therapeutic course of methylprednisolone acetate.
Journal of feline medicine and surgery.
2001 Jun; 3(2):87-93. doi:
10.1053/jfms.2001.0117. [PMID: 11876622] - H Furuichi, R Fukuyama, N Izumo, T Fujita, T Kohno, H Nakamuta, M Koida. Bone-anabolic effect of salmon calcitonin on glucocorticoid-induced osteopenia in rats.
Biological & pharmaceutical bulletin.
2000 Aug; 23(8):946-51. doi:
10.1248/bpb.23.946. [PMID: 10963301] - C Salvarani, F Cantini, I Olivieri, L Barozzi, L Macchioni, L Boiardi, L Niccoli, A Padula, L Pulsatelli, R Meliconi. Corticosteroid injections in polymyalgia rheumatica: a double-blind, prospective, randomized, placebo controlled study.
The Journal of rheumatology.
2000 Jun; 27(6):1470-6. doi:
NULL. [PMID: 10852273] - M C Barr, S Huitron-Resendiz, D R Selway, S J Henriksen, T R Phillips. Exogenous glucocorticoids alter parameters of early feline immunodeficiency virus infection.
The Journal of infectious diseases.
2000 Feb; 181(2):576-86. doi:
10.1086/315236. [PMID: 10669341] - L Manchikanti, V Pampati, B Fellows, C E Bakhit. The diagnostic validity and therapeutic value of lumbar facet joint nerve blocks with or without adjuvant agents.
Current review of pain.
2000; 4(5):337-44. doi:
10.1007/s11916-000-0016-4. [PMID: 10998741] - P Wiland, J Szechiński. N-acetyl-beta-D-glucosaminidase urinary excretion as an early indicator of kidney damage in rheumatoid arthritis patients starting on parenteral gold and Depo-Medrone/placebo injections.
Clinical rheumatology.
1999; 18(2):106-13. doi:
10.1007/s100670050066. [PMID: 10357114] - O P Minanov, J H Artrip, M Szabolcs, P A Kwiatkowski, U Galili, S Itescu, R E Michler. Triple immunosuppression reduces mononuclear cell infiltration and prolongs graft life in pig-to-newborn baboon cardiac xenotransplantation.
The Journal of thoracic and cardiovascular surgery.
1998 May; 115(5):998-1006. doi:
10.1016/s0022-5223(98)70397-6. [PMID: 9605067] - M R Ogborn, S Sareen. Transforming growth factor alpha and epidermal growth factor expression in experimental murine polycystic kidney disease.
Pediatric nephrology (Berlin, Germany).
1996 Apr; 10(2):181-4. doi:
10.1007/bf00862070. [PMID: 8703707] - J F Crocker, M E Schenk, D A Hamilton, D E Cole, A T McDonald, P D Acott. Thyroid hormone modulation of glucocorticoid-induced polycystic kidney disease.
Journal of the American Society of Nephrology : JASN.
1996 Apr; 7(4):633-4. doi:
10.1681/asn.v74633. [PMID: 8724899] - J D Lillich, A L Bertone, L M Schmall, A J Ruggles, R A Sams. Plasma, urine, and synovial fluid disposition of methylprednisolone acetate and isoflupredone acetate after intra-articular administration in horses.
American journal of veterinary research.
1996 Feb; 57(2):187-92. doi:
NULL. [PMID: 8633806] - M B Lazarevic, J L Skosey, G Djordjevic-Denic, W I Swedler, I Zgradic, B L Myones. Reduction of cortisol levels after single intra-articular and intramuscular steroid injection.
The American journal of medicine.
1995 Oct; 99(4):370-3. doi:
10.1016/s0002-9343(99)80183-1. [PMID: 7573091] - M R Ogborn, S Sareen, P C Grimm. Renal tubule Na,K-ATPase polarity in glucocorticoid-induced polycystic kidney disease.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
1993 Apr; 41(4):555-8. doi:
10.1177/41.4.8383715. [PMID: 8383715] - M R Ogborn, J F Crocker. Na-K ATPase activity in murine glucocorticoid induced polycystic kidney disease in vivo.
Clinical and investigative medicine. Medecine clinique et experimentale.
1993 Feb; 16(1):22-8. doi:
NULL. [PMID: 7682165] - N K Hopkins, C M Wagner, J Brisson, T E Addison. Validation of the simultaneous determination of methylprednisolone and methylprednisolone acetate in human plasma by high-performance liquid chromatography.
Journal of chromatography.
1992 May; 577(1):87-93. doi:
10.1016/0378-4347(92)80601-l. [PMID: 1400749] - M Matsui, S Saito, K Ohzono, N Sugano, M Saito, K Takaoka, K Ono. Experimental steroid-induced osteonecrosis in adult rabbits with hypersensitivity vasculitis.
Clinical orthopaedics and related research.
1992 Apr; ?(277):61-72. doi:
NULL. [PMID: 1555358] - T Ogawa, M Inazu, K Gotoh, T Inoue, S Hayashi. Therapeutic effects of leflunomide, a new antirheumatic drug, on glomerulonephritis induced by the antibasement membrane antibody in rats.
Clinical immunology and immunopathology.
1991 Oct; 61(1):103-18. doi:
10.1016/s0090-1229(06)80011-5. [PMID: 1959237] - R P McManus, T Kinney, R Komorowski, J Hunter. Reversibility of cardiac xenograft rejection in primates.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.
1991 Jul; 10(4):567-76. doi:
NULL. [PMID: 1911800] - A M Sadeghi, H Laks, D C Drinkwater, J M Pearl, P Chang, G Haas, C M Burnison, D Horton. Heart-lung xenotransplantation in primates.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.
1991 May; 10(3):442-7; discussion 447. doi:
NULL. [PMID: 1854771] - P B Kimsey, M E Goad, Z B Zhao, G Brackee, J G Fox. Methyl prednisolone acetate modulation of infection and subsequent pulmonary pathology in hamsters exposed to parainfluenza-1 virus (Sendai).
The American review of respiratory disease.
1989 Dec; 140(6):1704-11. doi:
10.1164/ajrccm/140.6.1704. [PMID: 2557786] - P T Reeves, P Hanrahan, J Edelman, K F Ilett. Effect of intra-articular glucocorticoids on the disposition of sulphadimidine in chronic osteoarthritis patients.
British journal of clinical pharmacology.
1988 Nov; 26(5):563-8. doi:
10.1111/j.1365-2125.1988.tb05296.x. [PMID: 3207561] - M R Colville, D D Aronson, P Prcevski, J D Crissman. The systemic and local effects of an intramedullary injection of methylprednisolone acetate in growing rabbits.
Journal of pediatric orthopedics.
1987 Jul; 7(4):412-4. doi:
10.1097/01241398-198707000-00006. [PMID: 3611336] - A M Sadeghi, R C Robbins, C R Smith, P A Kurlansky, R E Michler, K Reemtsma, E A Rose. Cardiac xenotransplantation in primates.
The Journal of thoracic and cardiovascular surgery.
1987 Jun; 93(6):809-14. doi:
10.1016/s0022-5223(19)37040-0. [PMID: 3553747] - M A Ros, J A García-Porrero, J L Ojeda. Duplication of slit diaphragms in the cystic glomeruli of rabbits treated with methylprednisolone acetate.
Acta anatomica.
1987; 130(4):362-5. doi:
10.1159/000146472. [PMID: 3434192] - A Autefage, M Alvinerie, P L Toutain. Synovial fluid and plasma kinetics of methylprednisolone and methylprednisolone acetate in horses following intra-articular administration of methylprednisolone acetate.
Equine veterinary journal.
1986 May; 18(3):193-8. doi:
10.1111/j.2042-3306.1986.tb03594.x. [PMID: 3732238] - P L Toutain, M Alvinerie, P Fayolle, Y Ruckebusch. Bovine plasma and synovial fluid kinetics of methylprednisolone and methylprednisolone acetate after intra-articular administration of methylprednisolone acetate.
The Journal of pharmacology and experimental therapeutics.
1986 Mar; 236(3):794-802. doi:
NULL. [PMID: 3950871] - P L Toutain, G D Koritz, P M Fayolle, M Alvinerie. Pharmacokinetics of methylprednisolone, methylprednisolone sodium succinate, and methylprednisolone acetate in dogs.
Journal of pharmaceutical sciences.
1986 Mar; 75(3):251-5. doi:
10.1002/jps.2600750309. [PMID: 3517294] - J L Ojeda, M A Ros, J A García-Porrero. Polycystic kidney disease induced by corticoids. A quantitative and qualitative analysis of cell populations in the tubular cysts.
Nephron.
1986; 42(3):240-8. doi:
10.1159/000183674. [PMID: 3945365] - S J King, H R Miller, G F Newlands, R G Woodbury. Depletion of mucosal mast cell protease by corticosteroids: effect on intestinal anaphylaxis in the rat.
Proceedings of the National Academy of Sciences of the United States of America.
1985 Feb; 82(4):1214-8. doi:
10.1073/pnas.82.4.1214. [PMID: 3883354] - M A Ros, J L Ojeda, J A García-Porrero. Vascular architecture modifications in the steroid-induced polycystic kidney.
Nephron.
1985; 40(3):332-40. doi:
10.1159/000183488. [PMID: 4010848] - S Jacobs, P T Pullan, J M Potter, G M Shenfield. Adrenal suppression following extradural steroids.
Anaesthesia.
1983 Oct; 38(10):953-6. doi:
10.1111/j.1365-2044.1983.tb12025.x. [PMID: 6314836] - G J Kociba, R D Lange, C D Dunn, E A Hoover. Serum erythropoietin changes in cats with feline leukemia virus-induced erythroid aplasia.
Veterinary pathology.
1983 Sep; 20(5):548-52. doi:
10.1177/030098588302000506. [PMID: 6314629] - A A Like, M Anthony, D L Guberski, A A Rossini. Spontaneous diabetes mellitus in the BB/W rat. Effects of glucocorticoids, cyclosporin-A, and antiserum to rat lymphocytes.
Diabetes.
1983 Apr; 32(4):326-30. doi:
10.2337/diab.32.4.326. [PMID: 6832488] - F M Engelbrecht, M Blom, L Laker, E Badenhorst. The effect of corticosteroid therapy on lysosomal enzymes and protein and lipid metabolism in rabbit lung after administration of Freund's adjuvant.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.
1982 Oct; 62(18):648-51. doi:
. [PMID: 7135114] - J L Ojeda, J A García-Porrero. Structure and development of parietal podocytes in renal glomerular cysts induced in rabbits with methylprednisolone acetate.
Laboratory investigation; a journal of technical methods and pathology.
1982 Aug; 47(2):167-76. doi:
NULL. [PMID: 7109541] - C Meyers, O Lockridge, B N La Du. Hydrolysis of methylprednisolone acetate by human serum cholinesterase.
Drug metabolism and disposition: the biological fate of chemicals.
1982 May; 10(3):279-80. doi:
NULL. [PMID: 6125364] - B P Stuart, D B Sisk, D M Bedell, H S Gosser. Demonstration of immunity against Isospora suis in swine.
Veterinary parasitology.
1982 Feb; 9(3-4):185-91. doi:
NULL. [PMID: 7201193] - R D Armstrong, J English, T Gibson, J Chakraborty, V Marks. Serum methylprednisolone levels following intra-articular injection of methylprednisolone acetate.
Annals of the rheumatic diseases.
1981 Dec; 40(6):571-4. doi:
10.1136/ard.40.6.571. [PMID: 7332377] - R J Kemppainen, M D Lorenz, F N Thompson. Adrenocortical suppression in the dog after a single dose of methylprednisolone acetate.
American journal of veterinary research.
1981 May; 42(5):822-4. doi:
NULL. [PMID: 6266293] - J L Ojeda, J A García-Porrero. Proximal tubule changes in the polycystic kidney induced by methylprednisolone acetate in the newborn rabbit. A microdissection-SEM study.
Experientia.
1981; 37(8):894-6. doi:
10.1007/bf01985700. [PMID: 7286149] - U Haglund, A Hellman, E Häggendal, J Häggendal. Ligation of the adrenal vessels--an incomplete technique to eliminate the plasma adrenaline content in the dog.
Acta physiologica Scandinavica.
1981; 113(3):407-9. doi:
10.1111/j.1748-1716.1981.tb06915.x. [PMID: 7345904] - S FERRARI, U FANTOLI. DURATION OF BLOOD AND URINARY LEVELS OF CORTICOSTEROID FOLLOWING INTRAMUSCULAR INJECTION OF METHYLPREDNISOLONE ACETATE.
Clinical medicine (Northfield, Ill.).
1964 Apr; 71(?):706-9. doi:
NULL. [PMID: 15446148]