Bithionol (BioDeep_00000006641)

 

Secondary id: BioDeep_00001867789

human metabolite blood metabolite


代谢物信息卡片


2,4-dichloro-6-[(3,5-dichloro-2-hydroxyphenyl)sulfanyl]phenol

化学式: C12H6Cl4O2S (353.8843)
中文名称: 硫双二氯酚
谱图信息: 最多检出来源 Homo sapiens(general) 45.95%

分子结构信息

SMILES: C1=C(C=C(C(=C1SC2=C(C(=CC(=C2)Cl)Cl)O)O)Cl)Cl
InChI: InChI=1S/C12H6Cl4O2S/c13-5-1-7(15)11(17)9(3-5)19-10-4-6(14)2-8(16)12(10)18/h1-4,17-18H

描述信息

CONFIDENCE standard compound; INTERNAL_ID 1364; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5307; ORIGINAL_PRECURSOR_SCAN_NO 5304
CONFIDENCE standard compound; INTERNAL_ID 1364; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5340; ORIGINAL_PRECURSOR_SCAN_NO 5338
CONFIDENCE standard compound; INTERNAL_ID 1364; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5314; ORIGINAL_PRECURSOR_SCAN_NO 5313
CONFIDENCE standard compound; INTERNAL_ID 1364; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5289; ORIGINAL_PRECURSOR_SCAN_NO 5286
CONFIDENCE standard compound; INTERNAL_ID 1364; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5359; ORIGINAL_PRECURSOR_SCAN_NO 5357
CONFIDENCE standard compound; INTERNAL_ID 1364; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5336; ORIGINAL_PRECURSOR_SCAN_NO 5335
D - Dermatologicals > D10 - Anti-acne preparations > D10A - Anti-acne preparations for topical use > D10AB - Preparations containing sulfur
P - Antiparasitic products, insecticides and repellents > P02 - Anthelmintics > P02B - Antitrematodals
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics
C254 - Anti-Infective Agent > C28394 - Topical Anti-Infective Agent

同义名列表

14 个代谢物同义名

2,4-dichloro-6-[(3,5-dichloro-2-hydroxyphenyl)sulfanyl]phenol; 2,2-Dihydroxy-3,3,5,5-tetrachlorodiphenyl sulphide; 2,2-Dihydroxy-3,3,5,5-tetrachlorodiphenyl sulfide; Bis(3,5-dichloro-2-hydroxyphenyl) sulphide; Bis(3,5-dichloro-2-hydroxyphenyl) sulfide; 2-Hydroxy-3,5-dichlorophenyl sulphide; 2-Hydroxy-3,5-dichlorophenyl sulfide; 2,2-Thiobis(4,6-dichlorophenol); Bithionol sulphide; Bithionol sulfide; bithionol; Bithin; Bitin; Bithionol



数据库引用编号

26 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 11 ADCY10, ADCY2, AIMP2, BCL2, BCL2L1, CASP3, GPBAR1, HPGDS, NAPEPLD, THRSP, XIAP
Peripheral membrane protein 2 ADCY10, NAPEPLD
Endoplasmic reticulum membrane 1 BCL2
Mitochondrion membrane 1 BCL2L1
Nucleus 9 ADCY10, AIMP2, BCL2, CASP3, FOXN1, MKI67, PARP1, THRSP, XIAP
cytosol 10 ADCY10, AIMP2, BCL2, BCL2L1, CASP3, HPGDS, LIPE, PARP1, THRSP, XIAP
dendrite 2 ADCY10, ADCY2
nuclear body 2 MKI67, PARP1
centrosome 1 BCL2L1
nucleoplasm 7 CASP3, HPGDS, MKI67, NAPEPLD, PARP1, THRSP, XIAP
Cell membrane 4 ADCY10, ADCY2, GPBAR1, LIPE
Cytoplasmic side 2 ADCY10, BCL2L1
Early endosome membrane 1 NAPEPLD
Multi-pass membrane protein 2 ADCY2, GPBAR1
Golgi apparatus membrane 1 NAPEPLD
glutamatergic synapse 1 CASP3
Golgi apparatus 1 NAPEPLD
Golgi membrane 2 INS, NAPEPLD
mitochondrial inner membrane 1 BCL2L1
neuronal cell body 2 ADCY10, CASP3
presynaptic membrane 1 NAPEPLD
Cytoplasm, cytosol 4 AIMP2, BCL2L1, LIPE, PARP1
plasma membrane 3 ADCY2, ENPP2, GPBAR1
synaptic vesicle membrane 1 BCL2L1
Membrane 7 ADCY2, AIMP2, BCL2, ENPP2, LIPE, MKI67, PARP1
apical plasma membrane 1 ADCY10
caveola 1 LIPE
extracellular exosome 2 NAPEPLD, TTR
endoplasmic reticulum 2 BCL2, BCL2L1
extracellular space 3 ENPP2, INS, TTR
perinuclear region of cytoplasm 1 ADCY10
mitochondrion 4 ADCY10, BCL2, BCL2L1, PARP1
protein-containing complex 2 BCL2, PARP1
intracellular membrane-bounded organelle 1 HPGDS
postsynaptic density 1 CASP3
Secreted 3 ENPP2, INS, TTR
extracellular region 4 ADCY10, ENPP2, INS, TTR
Mitochondrion outer membrane 2 BCL2, BCL2L1
Single-pass membrane protein 2 BCL2, BCL2L1
mitochondrial outer membrane 2 BCL2, BCL2L1
astrocyte end-foot 1 ADCY10
basal part of cell 1 ADCY10
central region of growth cone 1 ADCY10
hippocampal mossy fiber to CA3 synapse 1 NAPEPLD
Mitochondrion matrix 1 BCL2L1
mitochondrial matrix 1 BCL2L1
transcription regulator complex 1 PARP1
Cell projection, cilium 1 ADCY10
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 BCL2L1
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 BCL2L1
Nucleus membrane 2 BCL2, BCL2L1
Bcl-2 family protein complex 2 BCL2, BCL2L1
nuclear membrane 2 BCL2, BCL2L1
nucleolus 2 MKI67, PARP1
Early endosome 1 NAPEPLD
postsynaptic membrane 1 NAPEPLD
Cytoplasm, perinuclear region 1 ADCY10
Membrane raft 1 ADCY2
pore complex 1 BCL2
Cytoplasm, cytoskeleton 1 ADCY10
receptor complex 1 GPBAR1
cilium 1 ADCY10
chromatin 2 FOXN1, PARP1
Chromosome 2 MKI67, PARP1
cytoskeleton 1 ADCY10
Nucleus, nucleolus 2 MKI67, PARP1
nuclear replication fork 1 PARP1
chromosome, telomeric region 1 PARP1
site of double-strand break 1 PARP1
nuclear envelope 2 NAPEPLD, PARP1
Nucleus envelope 1 NAPEPLD
endosome lumen 1 INS
Lipid droplet 1 LIPE
Membrane, caveola 1 LIPE
Nucleus, nucleoplasm 1 NAPEPLD
Smooth endoplasmic reticulum membrane 1 NAPEPLD
myelin sheath 1 BCL2
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 1 INS
transport vesicle 1 INS
azurophil granule lumen 1 TTR
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
protein-DNA complex 1 PARP1
death-inducing signaling complex 1 CASP3
aminoacyl-tRNA synthetase multienzyme complex 1 AIMP2
photoreceptor outer segment membrane 1 NAPEPLD
site of DNA damage 1 PARP1
[Poly [ADP-ribose] polymerase 1, processed N-terminus]: Chromosome 1 PARP1
[Poly [ADP-ribose] polymerase 1, processed C-terminus]: Cytoplasm 1 PARP1
BAD-BCL-2 complex 1 BCL2
[Isoform Bcl-X(L)]: Mitochondrion inner membrane 1 BCL2L1


文献列表

  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Karl Kevala, Michel Lagarde, Arthur A Spector, Hee-Yong Kim. Biosynthesis of N-Docosahexanoylethanolamine from Unesterified Docosahexaenoic Acid and Docosahexaenoyl-Lysophosphatidylcholine in Neuronal Cells. International journal of molecular sciences. 2020 Nov; 21(22):. doi: 10.3390/ijms21228768. [PMID: 33233525]
  • Geetika Aggarwal, Jonah E Zarrow, Zahra Mashhadi, C Robb Flynn, Paige Vinson, C David Weaver, Sean S Davies. Symmetrically substituted dichlorophenes inhibit N-acyl-phosphatidylethanolamine phospholipase D. The Journal of biological chemistry. 2020 05; 295(21):7289-7300. doi: 10.1074/jbc.ra120.013362. [PMID: 32284327]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Wooseong Kim, Guijin Zou, Taylor P A Hari, Ingrid K Wilt, Wenpeng Zhu, Nicolas Galle, Hammad A Faizi, Gabriel L Hendricks, Katerina Tori, Wen Pan, Xiaowen Huang, Andrew D Steele, Erika E Csatary, Madeline M Dekarske, Jake L Rosen, Noelly de Queiroz Ribeiro, Kiho Lee, Jenna Port, Beth Burgwyn Fuchs, Petia M Vlahovska, William M Wuest, Huajian Gao, Frederick M Ausubel, Eleftherios Mylonakis. A selective membrane-targeting repurposed antibiotic with activity against persistent methicillin-resistant Staphylococcus aureus. Proceedings of the National Academy of Sciences of the United States of America. 2019 08; 116(33):16529-16534. doi: 10.1073/pnas.1904700116. [PMID: 31358625]
  • Emil Jakobsen, Sofie C Lange, Jens V Andersen, Claus Desler, Henriette F Kihl, Michaela C Hohnholt, Malin H Stridh, Lene J Rasmussen, Helle S Waagepetersen, Lasse K Bak. The inhibitors of soluble adenylate cyclase 2-OHE, KH7, and bithionol compromise mitochondrial ATP production by distinct mechanisms. Biochemical pharmacology. 2018 09; 155(?):92-101. doi: 10.1016/j.bcp.2018.06.023. [PMID: 29940175]
  • Matthew R Fleming, Maile R Brown, Jack Kronengold, Yalan Zhang, David P Jenkins, Gulia Barcia, Rima Nabbout, Anne E Bausch, Peter Ruth, Robert Lukowski, Dhasakumar S Navaratnam, Leonard K Kaczmarek. Stimulation of Slack K(+) Channels Alters Mass at the Plasma Membrane by Triggering Dissociation of a Phosphatase-Regulatory Complex. Cell reports. 2016 08; 16(9):2281-8. doi: 10.1016/j.celrep.2016.07.024. [PMID: 27545877]
  • Kana Matsubara, Seigo Sanoh, Shigeru Ohta, Shigeyuki Kitamura, Kazumi Sugihara, Nariaki Fujimoto. An improved thyroid hormone reporter assay to determine the thyroid hormone-like activity of amiodarone, bithionol, closantel and rafoxanide. Toxicology letters. 2012 Jan; 208(1):30-5. doi: 10.1016/j.toxlet.2011.10.004. [PMID: 22015988]
  • Shao-Hua Long, Zhu-Qin Yu, Li Shuai, Yun-Liang Guo, De-Lin Duan, Xin-Ying Xu, Xiao-Dan Li. The hypoglycemic effect of the kelp on diabetes mellitus model induced by alloxan in rats. International journal of molecular sciences. 2012; 13(3):3354-65. doi: 10.3390/ijms13033354. [PMID: 22489155]
  • Jennifer Keiser, Hanan Sayed, Maged el-Ghanam, Hoda Sabry, Saad Anani, Aly el-Wakeel, Christoph Hatz, Jürg Utzinger, Sayed Seif el-Din, Walaa el-Maadawy, Sanaa Botros. Efficacy and safety of artemether in the treatment of chronic fascioliasis in Egypt: exploratory phase-2 trials. PLoS neglected tropical diseases. 2011 Sep; 5(9):e1285. doi: 10.1371/journal.pntd.0001285. [PMID: 21909440]
  • Yasuto Kido, Pär Matsson, Kathleen M Giacomini. Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2. Journal of medicinal chemistry. 2011 Jul; 54(13):4548-58. doi: 10.1021/jm2001629. [PMID: 21599003]
  • Frank C Victor, David E Cohen, Nicholas A Soter. A 20-year analysis of previous and emerging allergens that elicit photoallergic contact dermatitis. Journal of the American Academy of Dermatology. 2010 Apr; 62(4):605-10. doi: 10.1016/j.jaad.2009.06.084. [PMID: 20163891]
  • Rajan F Ezzat, Taha A Karboli, Kalandar A Kasnazani, Adnan Mh Hamawandi. Endoscopic management of biliary fascioliasis: a case report. Journal of medical case reports. 2010 Mar; 4(?):83. doi: 10.1186/1752-1947-4-83. [PMID: 20205932]
  • Saki Takahashi, Yoichi Sakakibara, Emi Mishiro, Haruna Kouriki, Rika Nobe, Katsuhisa Kurogi, Shin Yasuda, Ming-Cheh Liu, Masahito Suiko. Molecular cloning, expression and characterization of a novel mouse SULT6 cytosolic sulfotransferase. Journal of biochemistry. 2009 Sep; 146(3):399-405. doi: 10.1093/jb/mvp087. [PMID: 19505954]
  • Ming Li, Christopher J Smith, Matthew T Walker, Thomas J Smith. Novel inhibitors complexed with glutamate dehydrogenase: allosteric regulation by control of protein dynamics. The Journal of biological chemistry. 2009 Aug; 284(34):22988-3000. doi: 10.1074/jbc.m109.020222. [PMID: 19531491]
  • Yoshinori Sanada, Hiroyuki Senba, Rieko Mochizuki, Hidemi Arakaki, Tadahiro Gotoh, Shin-Ichiro Fukumoto, Hajime Nagahata. Evaluation of marked rise in fecal egg output after bithionol administration to horse and its application as a diagnostic marker for equine Anoplocephala perfoliata infection. The Journal of veterinary medical science. 2009 May; 71(5):617-20. doi: 10.1292/jvms.71.617. [PMID: 19498288]
  • Judd L Walson, Grace John-Stewart. Treatment of helminth co-infection in individuals with HIV-1: A systematic review of the literature. PLoS neglected tropical diseases. 2007 Dec; 1(3):e102. doi: 10.1371/journal.pntd.0000102. [PMID: 18160978]
  • Renee L Florent, Joy A Becker, Mark D Powell. Evaluation of bithionol as a bath treatment for amoebic gill disease caused by Neoparamoeba spp. Veterinary parasitology. 2007 Mar; 144(3-4):197-207. doi: 10.1016/j.vetpar.2006.10.018. [PMID: 17129675]
  • D Y Aksoy, U Kerimoglu, A Oto, S Erguven, S Arslan, S Unal, F Batman, Y Bayraktar. Infection with Fasciola hepatica. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 2005 Nov; 11(11):859-61. doi: 10.1111/j.1469-0691.2005.01254.x. [PMID: 16216098]
  • C Ming-gang, C Zheng-shan, S Xiang-yuan, L Ming-da, D Blair, C Shao-hong, Z Yong-nian, H Jia-lin, S Bing-gui, F Zheng. Paragonimiasis in Yongjia County, Zhejiang Province, China: clinical, parasitological and karyotypic studies on Paragonimus westermani. The Southeast Asian journal of tropical medicine and public health. 2001 Dec; 32(4):760-9. doi: NULL. [PMID: 12041551]
  • A Cosme, E Ojeda, G Cilla, J Torrado, L Alzate, X Beristain, V Orive, J Arenas. [Fasciola hepatica. study of a series of 37 patients]. Gastroenterologia y hepatologia. 2001 Oct; 24(8):375-80. doi: 10.1016/s0210-5705(01)70204-x. [PMID: 11674955]
  • J C Carré, S Houmdaophet. [Paragonimiasis]. Revue de pneumologie clinique. 1998 Dec; 54(6):359-64. doi: NULL. [PMID: 10100349]
  • K Kodama. [Human fascioliasis: comparison of a fasciolicidal effect of bithionol and praziquantel]. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases. 1997 Nov; 71(11):1162-7. doi: 10.11150/kansenshogakuzasshi1970.71.1162. [PMID: 9455057]
  • M Almendras-Jaramillo, J Rivera-Medina, J Seijas-Mogrovejo, K Almendras-Jaramillo. [Hepatic fascioliasis in children: uncommon clinical manifestations]. Arquivos de gastroenterologia. 1997 Oct; 34(4):241-7. doi: . [PMID: 9629320]
  • M M Osman, E Rashwan, H F Farag. Phagocytic activity of neutrophils in human fasciolosis before and after treatment. Journal of the Egyptian Society of Parasitology. 1995 Aug; 25(2):321-7. doi: NULL. [PMID: 7665930]
  • A M Espino, C M Finlay. Sandwich enzyme-linked immunosorbent assay for detection of excretory secretory antigens in humans with fascioliasis. Journal of clinical microbiology. 1994 Jan; 32(1):190-3. doi: 10.1128/jcm.32.1.190-193.1994. [PMID: 8126178]
  • H K Bassiouny, N K Soliman, S M el-Daly, N M Badr. Human fascioliasis in Egypt: effect of infection and efficacy of bithionol treatment. The Journal of tropical medicine and hygiene. 1991 Oct; 94(5):333-7. doi: . [PMID: 1942212]
  • N Iwahashi, F Suzuki, S Tamura, Y Kawai, M Miyake, Y Matsuda, J Maeda, T Nakano, T Hada, K Higashino. [A case of paragonimiasis Miyazakii with bilateral pleural and pericardial effusion]. Nihon Kyobu Shikkan Gakkai zasshi. 1991 Aug; 29(8):1047-51. doi: . [PMID: 1753521]
  • S Z Abdel-Rahman, A M el-Sharkawy, L M Abou-Bacha, A Salem. Glutathione and related enzymes in fascioliasis before and after treatment with bithionol. The Journal of tropical medicine and hygiene. 1990 Oct; 93(5):337-40. doi: . [PMID: 1977927]
  • T Ebe, M Matsumura, T Mori, M Takahashi, T Kohara, M Inagaki, H Isonuma, I Hibiya, T Hamamoto, H Funayama. [Eight cases of diphyllobothriasis]. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases. 1990 Mar; 64(3):328-34. doi: 10.11150/kansenshogakuzasshi1970.64.328. [PMID: 2358713]
  • J N Delahanty, J C Evans, C C Rowlands, R U Pendlington, M D Barratt. The photochemical binding of bithionol to soluble proteins and peptides. Biochemical pharmacology. 1989 Nov; 38(21):3879-83. doi: 10.1016/0006-2952(89)90599-6. [PMID: 2480789]
  • H F Farag, A Salem, S A el-Hifni, M Kandil. Bithionol (Bitin) treatment in established fascioliasis in Egyptians. The Journal of tropical medicine and hygiene. 1988 Oct; 91(5):240-4. doi: . [PMID: 3184244]
  • D C Jenkins, P Topley, E B Rapson. Fasciola hepatica in vitro: increased susceptibility to fasciolicides in a defined serum-free medium. Parasitology. 1987 Aug; 95 ( Pt 1)(?):165-71. doi: 10.1017/s0031182000057644. [PMID: 3670897]
  • J Imai. Evaluation of ELISA for the diagnosis of paragonimiasis westermani. Transactions of the Royal Society of Tropical Medicine and Hygiene. 1987; 81(1):3-6. doi: 10.1016/0035-9203(87)90267-7. [PMID: 3127958]
  • T Takeuchi, S Kobayashi, M Tanabe, T Fujiwara. In vitro inhibition of Giardia lamblia and Trichomonas vaginalis growth by bithionol, dichlorophene, and hexachlorophene. Antimicrobial agents and chemotherapy. 1985 Jan; 27(1):65-70. doi: 10.1128/aac.27.1.65. [PMID: 3872626]
  • T Takeuchi, S Kobayashi, H Kawasaki. Entamoeba histolytica: inhibition in vitro by bithionol of respiratory activity and growth. Experimental parasitology. 1984 Aug; 58(1):1-7. doi: 10.1016/0014-4894(84)90015-8. [PMID: 6086381]
  • L M Abou Basha, A A Elmagdoub, S A Ebeid, M A Toukhy, A I Michael, K M Hosny, S M El Zoghby, H F Faraq, M F El Sawy. Effect of bithionol on B-glucuronidase in serum and liver of rabbits infected with Fasciola gigantica. Journal of the Egyptian Society of Parasitology. 1983 Jun; 13(1):231-8. doi: NULL. [PMID: 6631102]
  • M Dagorn. [Autoradiographic study of the distribution of 14C bithionol sulfoxide in mice (author's transl)]. Toxicological European research. Recherche europeenne en toxicologie. 1982 Mar; 4(2):101-5. doi: NULL. [PMID: 7112565]
  • M Sakamoto, K Chiba, I Agata, T Higa, M Kiyota, N Hayashi, N Yagi, M Itoh, H Sekikawa, M Takada. Metabolic detoxication of bis-(2-hydroxy-3, 5-dichlorophenyl)-sulfoxide in man. The Journal of toxicological sciences. 1981 Nov; 6(4):307-14. doi: 10.2131/jts.6.307. [PMID: 7338961]
  • M Faehlmann, L Hambraeus, L Lindqvist, O Paulsen, P O Pehrson. [The liver fluke - the 1st imported cases?]. Lakartidningen. 1981 Mar; 78(10):961-2. doi: NULL. [PMID: 7206937]
  • G J Mayer. Pulmonary paragonimiasis. The Journal of pediatrics. 1979 Jul; 95(1):75-6. doi: 10.1016/s0022-3476(79)80088-8. [PMID: 480017]
  • ". [Committee on anthelmintics. Residual group]. Tijdschrift voor diergeneeskunde. 1975 Nov; 100(21):1156-9. doi: ". [PMID: 1198575]
  • M S Iagudaev. [Effect of a high-protein diet on the effectiveness of fenasal and other anthelmintics in white mice infected with Hymenolepis nana]. Meditsinskaia parazitologiia i parazitarnye bolezni. 1974 May; 43(3):305-7. doi: ". [PMID: 4459698]