Bithionol (BioDeep_00000006641)

human metabolite blood metabolite

代谢物信息卡片

2,4-dichloro-6-[(3,5-dichloro-2-hydroxyphenyl)sulfanyl]phenol

化学式: C12H6Cl4O2S (353.88426160000006)
中文名称: 硫双二氯酚
谱图信息: 最多检出来源 Homo sapiens(blood) 66.67%

分子结构信息

SMILES: C1=C(C=C(C(=C1SC2=C(C(=CC(=C2)Cl)Cl)O)O)Cl)Cl
InChI: InChI=1S/C12H6Cl4O2S/c13-5-1-7(15)11(17)9(3-5)19-10-4-6(14)2-8(16)12(10)18/h1-4,17-18H

描述信息

CONFIDENCE standard compound; INTERNAL_ID 1364; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5307; ORIGINAL_PRECURSOR_SCAN_NO 5304
CONFIDENCE standard compound; INTERNAL_ID 1364; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5340; ORIGINAL_PRECURSOR_SCAN_NO 5338
CONFIDENCE standard compound; INTERNAL_ID 1364; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5314; ORIGINAL_PRECURSOR_SCAN_NO 5313
CONFIDENCE standard compound; INTERNAL_ID 1364; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5289; ORIGINAL_PRECURSOR_SCAN_NO 5286
CONFIDENCE standard compound; INTERNAL_ID 1364; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5359; ORIGINAL_PRECURSOR_SCAN_NO 5357
CONFIDENCE standard compound; INTERNAL_ID 1364; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5336; ORIGINAL_PRECURSOR_SCAN_NO 5335
D - Dermatologicals > D10 - Anti-acne preparations > D10A - Anti-acne preparations for topical use > D10AB - Preparations containing sulfur
P - Antiparasitic products, insecticides and repellents > P02 - Anthelmintics > P02B - Antitrematodals
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics
C254 - Anti-Infective Agent > C28394 - Topical Anti-Infective Agent

同义名列表

13 个代谢物同义名

2,4-dichloro-6-[(3,5-dichloro-2-hydroxyphenyl)sulfanyl]phenol; 2,2-Dihydroxy-3,3,5,5-tetrachlorodiphenyl sulphide; 2,2-Dihydroxy-3,3,5,5-tetrachlorodiphenyl sulfide; Bis(3,5-dichloro-2-hydroxyphenyl) sulphide; Bis(3,5-dichloro-2-hydroxyphenyl) sulfide; 2-Hydroxy-3,5-dichlorophenyl sulphide; 2-Hydroxy-3,5-dichlorophenyl sulfide; 2,2-Thiobis(4,6-dichlorophenol); Bithionol sulphide; Bithionol sulfide; bithionol; Bithin; Bitin

数据库引用编号

25 个数据库交叉引用编号

ChEBI: CHEBI:3131
KEGG: C77336
KEGG: C07967
KEGGdrug: D00802
PubChem: 2406
HMDB: HMDB0249278
Metlin: METLIN43584
DrugBank: DB04813
ChEMBL: CHEMBL290106
Wikipedia: Bithionol
MeSH: Bithionol
chemspider: 2313
CAS: 1394-04-3
CAS: 97-18-7
MoNA: LU136454
MoNA: LU136451
MoNA: LU136452
MoNA: LU136456
MoNA: LU136453
MoNA: LU136455
PMhub: MS000019713
PubChem: 10168
PDB-CCD: B1T
NIKKAJI: J4.438E
RefMet: Bithionol

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

9606 - Homo sapiens: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
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