Pteroic acid (BioDeep_00000006542)
Secondary id: BioDeep_00001869134
human metabolite PANOMIX_OTCML-2023 blood metabolite
代谢物信息卡片
化学式: C14H12N6O3 (312.0971)
中文名称: 蝶酸
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 50%
分子结构信息
SMILES: C1=CC(=CC=C1C(=O)O)NCC2=CN=C3C(=N2)C(=O)NC(=N3)N
InChI: InChI=1S/C14H12N6O3/c15-14-19-11-10(12(21)20-14)18-9(6-17-11)5-16-8-3-1-7(2-4-8)13(22)23/h1-4,6,16H,5H2,(H,22,23)(H3,15,17,19,20,21)
描述信息
同义名列表
10 个代谢物同义名
4-(((2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl)amino)benzoic acid; 4-{[(2-amino-4-hydroxypteridin-6-yl)methyl]amino}benzoic acid; p-((2-Amino-4-hydroxy-6-pteridylmethyl)amino)benzoic acid; 4-((2-Amino-4-hydroxy-6-pteridylmethyl)amino)benzoic acid; 4-{[(2-amino-4-hydroxypteridin-6-yl)methyl]amino}benzoate; p-((2-Amino-4-hydroxy-6-pteridylmethyl)amino)benzoate; 4-((2-Amino-4-hydroxy-6-pteridylmethyl)amino)benzoate; Pteroic acid; Pteroate; Pteroic acid
数据库引用编号
18 个数据库交叉引用编号
- ChEBI: CHEBI:37066
- ChEBI: CHEBI:27623
- ChEBI: CHEBI:37055
- KEGG: C07582
- PubChem: 135398749
- HMDB: HMDB0256914
- Metlin: METLIN66690
- DrugBank: DB04196
- ChEMBL: CHEMBL341824
- chemspider: 85769
- CAS: 119-24-4
- PMhub: MS000019594
- PubChem: 9784
- PDB-CCD: 22D
- PDB-CCD: APT
- PDB-CCD: PT1
- NIKKAJI: J10.073K
- KNApSAcK: 27623
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- J Enrique Salcedo-Sora, Edwin Ochong, Susan Beveridge, David Johnson, Alexis Nzila, Giancarlo A Biagini, Paul A Stocks, Paul M O'Neill, Sanjeev Krishna, Patrick G Bray, Stephen A Ward. The molecular basis of folate salvage in Plasmodium falciparum: characterization of two folate transporters.
The Journal of biological chemistry.
2011 Dec; 286(52):44659-68. doi:
10.1074/jbc.m111.286054. [PMID: 21998306] - Michael Pierce, Jennifer Nielsen Kahn, Jiachi Chiou, Nilgun E Tumer. Development of a quantitative RT-PCR assay to examine the kinetics of ribosome depurination by ribosome inactivating proteins using Saccharomyces cerevisiae as a model.
RNA (New York, N.Y.).
2011 Jan; 17(1):201-10. doi:
10.1261/rna.2375411. [PMID: 21098653] - Vinita Mishra, C V S Siva Prasad. Ligand based virtual screening to find novel inhibitors against plant toxin Ricin by using the ZINC database.
Bioinformation.
2011; 7(2):46-51. doi:
10.6026/97320630007046. [PMID: 21938204] - Christopher P Leamon, Scott R Cooper, Gregory E Hardee. Folate-liposome-mediated antisense oligodeoxynucleotide targeting to cancer cells: evaluation in vitro and in vivo.
Bioconjugate chemistry.
2003 Jul; 14(4):738-47. doi:
10.1021/bc020089t. [PMID: 12862426] - Darcie J Miller, Kabyadi Ravikumar, Huafeng Shen, Jung-Keun Suh, Sean M Kerwin, Jon D Robertus. Structure-based design and characterization of novel platforms for ricin and shiga toxin inhibition.
Journal of medicinal chemistry.
2002 Jan; 45(1):90-8. doi:
10.1021/jm010186s. [PMID: 11754581] - J M Pascal, P J Day, A F Monzingo, S R Ernst, J D Robertus, R Iglesias, Y Pérez, J M Férreras, L Citores, T Girbés. 2.8-A crystal structure of a nontoxic type-II ribosome-inactivating protein, ebulin l.
Proteins.
2001 May; 43(3):319-26. doi:
10.1002/prot.1043. [PMID: 11288182] - I V Kurinov, D E Myers, J D Irvin, F M Uckun. X-ray crystallographic analysis of the structural basis for the interactions of pokeweed antiviral protein with its active site inhibitor and ribosomal RNA substrate analogs.
Protein science : a publication of the Protein Society.
1999 Sep; 8(9):1765-72. doi:
10.1110/ps.8.9.1765. [PMID: 10493577] - C P Leamon, R B DePrince, R W Hendren. Folate-mediated drug delivery: effect of alternative conjugation chemistry.
Journal of drug targeting.
1999; 7(3):157-69. doi:
10.3109/10611869909085499. [PMID: 10680972] - C E Butterworth, J A Plumb, J M Grizzle. Abnormal folate metabolism in feed-related anemia of cultured channel catfish.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.).
1986 Jan; 181(1):49-58. doi:
10.3181/00379727-181-42223. [PMID: 3945624] - J K Seydel, W Butte. P-Aminobenzoic acid derivatives. Mode of action and structure-activity relationships in a cell-free system (Escherichia coli).
Journal of medicinal chemistry.
1977 Mar; 20(3):439-47. doi:
10.1021/jm00213a023. [PMID: 321779]
