Phenylmethylsulfonyl fluoride (BioDeep_00000006313)
Secondary id: BioDeep_00001868069
human metabolite blood metabolite
代谢物信息卡片
Fluoride, benzenemethanesulfonyl
化学式: C7H7FO2S (174.0150774)
中文名称: PMSF溶液
谱图信息:
最多检出来源 Homo sapiens(blood) 66.67%
分子结构信息
SMILES: C1=CC=C(C=C1)CS(=O)(=O)F
InChI: InChI=1S/C7H7FO2S/c8-11(9,10)6-7-4-2-1-3-5-7/h1-5H,6H2
描述信息
Component of corn gluten (Zea mays). obtained comly. by extraction of corn gluten with alkaline aq. 2-propanol. Moisture control agent. It is used in edible coatings for nuts and other foods and as a binder in confectionery glazes. GRAS approved
D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors
同义名列表
17 个代谢物同义名
Fluoride, benzenemethanesulfonyl; Benzenemethanesulphonyl fluoride; Benzenemethanesulfonyl fluoride; alpha-Toluenesulphonyl fluoride; Fluoride, phenylmethanesulfonyl; alpha-Toluenesulfonyl fluoride; Fluoride, phenylmethylsulfonyl; Phenylmethylsulphonyl fluoride; Phenylmethanesulfonyl fluoride; Phenylmethylsulphonylfluoride; Phenylmethylsulfonyl fluoride; a-Toluenesulphonyl fluoride; Α-toluenesulphonyl fluoride; Α-toluenesulfonyl fluoride; a-Toluenesulfonyl fluoride; Zein; PMSF
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:8102
- KEGG: C06747
- PubChem: 4784
- HMDB: HMDB0256652
- Metlin: METLIN66517
- ChEMBL: CHEMBL190503
- Wikipedia: Phenylmethanesulfonylfluoride
- MeSH: Phenylmethylsulfonyl Fluoride
- MetaCyc: CPD-5541
- foodb: FDB016982
- chemspider: 4620
- CAS: 329-98-6
- PMhub: MS000019337
- PubChem: 8968
- PDB-CCD: PMF
- NIKKAJI: J150.773G
分类词条
相关代谢途径
Reactome(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
3 个相关的物种来源信息
- 43503 Ixora coccinea: 10.1016/J.BMCL.2010.10.058
- 43503 Ixora coccinea: 10.1016/J.BMCL.2010.10.058
- 9606 Homo sapiens: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Cory L Brooks, David A Ostrov, Nicholas C Schumann, Schuchi Kakkad, Danmeng Li, Karla Peña, Brady Paul Williams, Nathan E Goldfarb. 2.1 Å crystal structure of the Mycobacterium tuberculosis serine hydrolase, Hip1, in its anhydro-form (Anhydrohip1).
Biochemical and biophysical research communications.
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Cell reports.
2021 04; 35(4):109040. doi:
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FEBS letters.
2021 02; 595(3):379-388. doi:
10.1002/1873-3468.14014. [PMID: 33263189] - Zhao-Lin Ji, Shuai Peng, Li-Li Chen, Yang Liu, Chun Yan, Feng Zhu. Identification and characterization of a serine protease from Bacillus licheniformis W10: A potential antifungal agent.
International journal of biological macromolecules.
2020 Feb; 145(?):594-603. doi:
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Molecular plant pathology.
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Molecular pharmacology.
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Journal of pharmaceutical and biomedical analysis.
2018 May; 153(?):267-273. doi:
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Analytica chimica acta.
2015 Sep; 893(?):77-83. doi:
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The Korean journal of internal medicine.
2012 Jun; 27(2):163-70. doi:
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2012 Jun; 27(6):709-14. doi:
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2012 May; 68(5):692-701. doi:
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Nutrition & metabolism.
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2012 Apr; 12(?):31. doi:
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2012 Apr; 63(7):2579-93. doi:
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The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology.
2012 Apr; 16(2):91-5. doi:
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Korean journal of ophthalmology : KJO.
2012 Apr; 26(2):123-31. doi:
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Proteome science.
2012 Mar; 10(?):25. doi:
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BMC complementary and alternative medicine.
2012 Mar; 12(?):17. doi:
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Journal of veterinary science.
2012 Mar; 13(1):7-13. doi:
10.4142/jvs.2012.13.1.7. [PMID: 22437530] - Axel Tiessen, Annika Nerlich, Benjamin Faix, Christine Hümmer, Simon Fox, Kay Trafford, Hans Weber, Winfriede Weschke, Peter Geigenberger. Subcellular analysis of starch metabolism in developing barley seeds using a non-aqueous fractionation method.
Journal of experimental botany.
2012 Mar; 63(5):2071-87. doi:
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Biochimie.
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BMC complementary and alternative medicine.
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Histochemistry and cell biology.
2012 Feb; 137(2):205-16. doi:
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Journal of experimental botany.
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PLoS pathogens.
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2012 Feb; 63(3):1167-83. doi:
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Journal of neuroinflammation.
2012 Jan; 9(?):24. doi:
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BMC biochemistry.
2012 Jan; 13(?):2. doi:
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BMC cell biology.
2012 Jan; 13(?):2. doi:
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Plant methods.
2012 Jan; 8(1):1. doi:
10.1186/1746-4811-8-1. [PMID: 22243738] - Sophie Doublier, Dimas C Belisario, Manuela Polimeni, Laura Annaratone, Chiara Riganti, Elena Allia, Dario Ghigo, Amalia Bosia, Anna Sapino. HIF-1 activation induces doxorubicin resistance in MCF7 3-D spheroids via P-glycoprotein expression: a potential model of the chemo-resistance of invasive micropapillary carcinoma of the breast.
BMC cancer.
2012 Jan; 12(?):4. doi:
10.1186/1471-2407-12-4. [PMID: 22217342] - Naveen Sharma, Carlos M Castorena, Gregory D Cartee. Tissue-specific responses of IGF-1/insulin and mTOR signaling in calorie restricted rats.
PloS one.
2012; 7(6):e38835. doi:
10.1371/journal.pone.0038835. [PMID: 22701721] - Hua Sun, Linghong Yu, Huailing Wei, Gengtao Liu. A novel antihepatitis drug, bicyclol, prevents liver carcinogenesis in diethylnitrosamine-initiated and phenobarbital-promoted mice tumor model.
Journal of biomedicine & biotechnology.
2012; 2012(?):584728. doi:
10.1155/2012/584728. [PMID: 22500097] - Chi-Ling Fu, Justin I Odegaard, De'Broski R Herbert, Michael H Hsieh. A novel mouse model of Schistosoma haematobium egg-induced immunopathology.
PLoS pathogens.
2012; 8(3):e1002605. doi:
10.1371/journal.ppat.1002605. [PMID: 22479181] - Weiwei Huang, Tiantian He, Chengsen Chai, Yuan Yang, Yahong Zheng, Pei Zhou, Xiaoxia Qiao, Bin Zhang, Zengzhen Liu, Junru Wang, Changhong Shi, Liping Lei, Kun Gao, Hewei Li, Sue Zhong, Libo Yao, Meng-Er Huang, Ming Lei. Triptolide inhibits the proliferation of prostate cancer cells and down-regulates SUMO-specific protease 1 expression.
PloS one.
2012; 7(5):e37693. doi:
10.1371/journal.pone.0037693. [PMID: 22666381] - Casper Søgaard, Anne Stenbæk, Sophie Bernard, Masood Hadi, Azeddine Driouich, Henrik Vibe Scheller, Yumiko Sakuragi. GO-PROMTO illuminates protein membrane topologies of glycan biosynthetic enzymes in the Golgi apparatus of living tissues.
PloS one.
2012; 7(2):e31324. doi:
10.1371/journal.pone.0031324. [PMID: 22363620] - Maria Luisa Sirico, Bruna Guida, Alfredo Procino, Andrea Pota, Maurizio Sodo, Giuseppe Grandaliano, Simona Simone, Giovanni Pertosa, Eleonora Riccio, Bruno Memoli. Human mature adipocytes express albumin and this expression is not regulated by inflammation.
Mediators of inflammation.
2012; 2012(?):236796. doi:
10.1155/2012/236796. [PMID: 22675238] - Angelina E Altshuler, Alexander H Penn, Jessica A Yang, Ga-Ram Kim, Geert W Schmid-Schönbein. Protease activity increases in plasma, peritoneal fluid, and vital organs after hemorrhagic shock in rats.
PloS one.
2012; 7(3):e32672. doi:
10.1371/journal.pone.0032672. [PMID: 22479334] - Amanda Bernardes, Fernanda A H Batista, Mario de Oliveira Neto, Ana Carolina M Figueira, Paul Webb, Daniel Saidemberg, Mario S Palma, Igor Polikarpov. Low-resolution molecular models reveal the oligomeric state of the PPAR and the conformational organization of its domains in solution.
PloS one.
2012; 7(2):e31852. doi:
10.1371/journal.pone.0031852. [PMID: 22363753] - René Anour, Olena Andrukhova, Eva Ritter, Ute Zeitz, Reinhold G Erben. Klotho lacks a vitamin D independent physiological role in glucose homeostasis, bone turnover, and steady-state PTH secretion in vivo.
PloS one.
2012; 7(2):e31376. doi:
10.1371/journal.pone.0031376. [PMID: 22319626] - Mohammad Moneruzzaman Khandaker, Amru Nasrulhaq Boyce, Normaniza Osman, Abm Sharif Hossain. Physiochemical and phytochemical properties of wax apple (Syzygium samarangense [Blume] Merrill & L. M. Perry var. Jambu Madu) as affected by growth regulator application.
TheScientificWorldJournal.
2012; 2012(?):728613. doi:
10.1100/2012/728613. [PMID: 22701370] - Teresa Morera-Herreras, Cristina Miguelez, Asier Aristieta, José Ángel Ruiz-Ortega, Luisa Ugedo. Endocannabinoid modulation of dopaminergic motor circuits.
Frontiers in pharmacology.
2012; 3(?):110. doi:
10.3389/fphar.2012.00110. [PMID: 22701427] - Alexander V Chibalin, Judith A Heiny, Boubacar Benziane, Alexander V Prokofiev, Alexander V Vasiliev, Violetta V Kravtsova, Igor I Krivoi. Chronic nicotine modifies skeletal muscle Na,K-ATPase activity through its interaction with the nicotinic acetylcholine receptor and phospholemman.
PloS one.
2012; 7(3):e33719. doi:
10.1371/journal.pone.0033719. [PMID: 22442718] - Bryan N Kahner, Hisashi Kato, Asoka Banno, Mark H Ginsberg, Sanford J Shattil, Feng Ye. Kindlins, integrin activation and the regulation of talin recruitment to αIIbβ3.
PloS one.
2012; 7(3):e34056. doi:
10.1371/journal.pone.0034056. [PMID: 22457811] - Mohamad Hamshou, Els J M Van Damme, Gianni Vandenborre, Bart Ghesquière, Geert Trooskens, Kris Gevaert, Guy Smagghe. GalNAc/Gal-binding Rhizoctonia solani agglutinin has antiproliferative activity in Drosophila melanogaster S2 cells via MAPK and JAK/STAT signaling.
PloS one.
2012; 7(4):e33680. doi:
10.1371/journal.pone.0033680. [PMID: 22529896] - Zhaojing Hao, Li Zheng, Lan Kluwe, Weida Huang. Ferritin light chain and squamous cell carcinoma antigen 1 are coreceptors for cellular attachment and entry of hepatitis B virus.
International journal of nanomedicine.
2012; 7(?):827-34. doi:
10.2147/ijn.s27803. [PMID: 22359459] - Emma Mormeneo, Cecilia Jimenez-Mallebrera, Xavier Palomer, Valeria De Nigris, Manuel Vázquez-Carrera, Anna Orozco, Andrés Nascimento, Jaume Colomer, Carles Lerín, Anna M Gómez-Foix. PGC-1α induces mitochondrial and myokine transcriptional programs and lipid droplet and glycogen accumulation in cultured human skeletal muscle cells.
PloS one.
2012; 7(1):e29985. doi:
10.1371/journal.pone.0029985. [PMID: 22272266] - Guixian Wang, Weitang Yuan, Tae-Hwan Kwon, Zhenzhen Li, Jianguo Wen, Sukru Oguzkan Topcu, Jens Christian Djurhuus, Søren Nielsen, Jørgen Frøkiær. Age-related changes in expression in renal AQPs in response to congenital, partial, unilateral ureteral obstruction in rats.
Pediatric nephrology (Berlin, Germany).
2012 Jan; 27(1):83-94. doi:
10.1007/s00467-011-1878-x. [PMID: 22028046] - Mario D Cordero, Francisco Javier Cano-García, Elísabet Alcocer-Gómez, Manuel De Miguel, José Antonio Sánchez-Alcázar. Oxidative stress correlates with headache symptoms in fibromyalgia: coenzyme Q₁₀ effect on clinical improvement.
PloS one.
2012; 7(4):e35677. doi:
10.1371/journal.pone.0035677. [PMID: 22532869] - Dennys E Cintra, Eduardo R Ropelle, Juliana C Moraes, José R Pauli, Joseane Morari, Claudio T de Souza, Renato Grimaldi, Marcela Stahl, José B Carvalheira, Mario J Saad, Licio A Velloso. Unsaturated fatty acids revert diet-induced hypothalamic inflammation in obesity.
PloS one.
2012; 7(1):e30571. doi:
10.1371/journal.pone.0030571. [PMID: 22279596] - Sang-Hun Kang, Soo-Jin Jeong, Sun-Hee Kim, Ji-Hyun Kim, Ji Hoon Jung, Wonil Koh, Jung Hyo Kim, Dae Keun Kim, Chang-Yan Chen, Sung-Hoon Kim. Icariside II induces apoptosis in U937 acute myeloid leukemia cells: role of inactivation of STAT3-related signaling.
PloS one.
2012; 7(4):e28706. doi:
10.1371/journal.pone.0028706. [PMID: 22493659] - Liang Yang, Wei Ji, Peng Gao, Yong Li, Hua Cai, Xi Bai, Qin Chen, Yanming Zhu. GsAPK, an ABA-activated and calcium-independent SnRK2-type kinase from G. soja, mediates the regulation of plant tolerance to salinity and ABA stress.
PloS one.
2012; 7(3):e33838. doi:
10.1371/journal.pone.0033838. [PMID: 22439004] - Francisco J Ortega, José M Moreno-Navarrete, Dolores Mayas, Eva García-Santos, María Gómez-Serrano, José I Rodriguez-Hermosa, Bartomeu Ruiz, Wifredo Ricart, Francisco J Tinahones, Gema Frühbeck, Belen Peral, José M Fernández-Real. Breast cancer 1 (BrCa1) may be behind decreased lipogenesis in adipose tissue from obese subjects.
PloS one.
2012; 7(5):e33233. doi:
10.1371/journal.pone.0033233. [PMID: 22666314] - Jeffrey C Waller, Kenneth W Ellens, Sophie Alvarez, Karen Loizeau, Stéphane Ravanel, Andrew D Hanson. Mitochondrial and plastidial COG0354 proteins have folate-dependent functions in iron-sulphur cluster metabolism.
Journal of experimental botany.
2012 Jan; 63(1):403-11. doi:
10.1093/jxb/err286. [PMID: 21984653] - Xiaoning Chen, Kara J Margolis, Michael D Gershon, Gary J Schwartz, Ji Y Sze. Reduced serotonin reuptake transporter (SERT) function causes insulin resistance and hepatic steatosis independent of food intake.
PloS one.
2012; 7(3):e32511. doi:
10.1371/journal.pone.0032511. [PMID: 22412882] - Xin Wang, Zunji Ke, Gang Chen, Mei Xu, Kimberly A Bower, Jacqueline A Frank, Zhuo Zhang, Xianglin Shi, Jia Luo. Cdc42-dependent activation of NADPH oxidase is involved in ethanol-induced neuronal oxidative stress.
PloS one.
2012; 7(5):e38075. doi:
10.1371/journal.pone.0038075. [PMID: 22662267] - Zhifeng Huang, Guanghui Zhu, Chuanchuan Sun, Jingui Zhang, Yi Zhang, Youting Zhang, Chaohui Ye, Xiaojie Wang, Dariush Ilghari, Xiaokun Li. A novel solid-phase site-specific PEGylation enhances the in vitro and in vivo biostabilty of recombinant human keratinocyte growth factor 1.
PloS one.
2012; 7(5):e36423. doi:
10.1371/journal.pone.0036423. [PMID: 22574160] - Giuseppe Procino, Lisa Mastrofrancesco, Grazia Tamma, Domenica Rita Lasorsa, Marianna Ranieri, Gilda Stringini, Francesco Emma, Maria Svelto, Giovanna Valenti. Calcium-sensing receptor and aquaporin 2 interplay in hypercalciuria-associated renal concentrating defect in humans. An in vivo and in vitro study.
PloS one.
2012; 7(3):e33145. doi:
10.1371/journal.pone.0033145. [PMID: 22403735] - Chung-Hung Shih, Ling-Hung Lin, Hsin-Te Hsu, Kuo-Hsien Wang, Chi-Yin Lai, Chien-Ming Chen, Wun-Chang Ko. Hesperetin, a Selective Phosphodiesterase 4 Inhibitor, Effectively Suppresses Ovalbumin-Induced Airway Hyperresponsiveness without Influencing Xylazine/Ketamine-Induced Anesthesia.
Evidence-based complementary and alternative medicine : eCAM.
2012; 2012(?):472897. doi:
10.1155/2012/472897. [PMID: 22454667] - Siham Yasari, Denis Prud'homme, Frédérique Tesson, Marek Jankowski, Jolanta Gutkowska, Emile Levy, Jean-Marc Lavoie. Effects of exercise training on molecular markers of lipogenesis and lipid partitioning in fructose-induced liver fat accumulation.
Journal of nutrition and metabolism.
2012; 2012(?):181687. doi:
10.1155/2012/181687. [PMID: 21860785] - Trevor Glaros, Yan Fu, Jianhua Xing, Liwu Li. Molecular mechanism underlying persistent induction of LCN2 by lipopolysaccharide in kidney fibroblasts.
PloS one.
2012; 7(4):e34633. doi:
10.1371/journal.pone.0034633. [PMID: 22514649] - Sishuo Cao, Wentao Xu, Nan Zhang, Yan Wang, YunBo Luo, Xiaoyun He, Kunlun Huang. A mitochondria-dependent pathway mediates the apoptosis of GSE-induced yeast.
PloS one.
2012; 7(3):e32943. doi:
10.1371/journal.pone.0032943. [PMID: 22403727] - Thing-Fong Tzeng, Hung-Jen Lu, Shorong-Shii Liou, Chia Ju Chang, I-Min Liu. Emodin, a Naturally Occurring Anthraquinone Derivative, Ameliorates Dyslipidemia by Activating AMP-Activated Protein Kinase in High-Fat-Diet-Fed Rats.
Evidence-based complementary and alternative medicine : eCAM.
2012; 2012(?):781812. doi:
10.1155/2012/781812. [PMID: 22649478] - Elena A Sher, Mati Shaklai, Nurith Shaklai. Carbon monoxide promotes respiratory hemoproteins iron reduction using peroxides as electron donors.
PloS one.
2012; 7(3):e33039. doi:
10.1371/journal.pone.0033039. [PMID: 22427940] - Sung A Jung, Miseon Choi, Sohee Kim, Rina Yu, Taesun Park. Cinchonine Prevents High-Fat-Diet-Induced Obesity through Downregulation of Adipogenesis and Adipose Inflammation.
PPAR research.
2012; 2012(?):541204. doi:
10.1155/2012/541204. [PMID: 22675336] - Kenji Matsui, Kohichi Sugimoto, Jun'ichi Mano, Rika Ozawa, Junji Takabayashi. Differential metabolisms of green leaf volatiles in injured and intact parts of a wounded leaf meet distinct ecophysiological requirements.
PloS one.
2012; 7(4):e36433. doi:
10.1371/journal.pone.0036433. [PMID: 22558466] - Xiaohua Han, Yihua Wang, Xi Liu, Ling Jiang, Yulong Ren, Feng Liu, Cheng Peng, Jingjing Li, Ximing Jin, Fuqing Wu, Jiulin Wang, Xiuping Guo, Xin Zhang, Zhijun Cheng, Jianmin Wan. The failure to express a protein disulphide isomerase-like protein results in a floury endosperm and an endoplasmic reticulum stress response in rice.
Journal of experimental botany.
2012 Jan; 63(1):121-30. doi:
10.1093/jxb/err262. [PMID: 21984651] - Maizom Hassan, Nur Diyana Maarof, Zainon Mohd Ali, Normah Mohd Noor, Roohaida Othman, Nobuhiro Mori. Monoterpene alcohol metabolism: identification, purification, and characterization of two geraniol dehydrogenase isoenzymes from Polygonum minus leaves.
Bioscience, biotechnology, and biochemistry.
2012; 76(8):1463-70. doi:
10.1271/bbb.120137. [PMID: 22878188] - Yucun Niu, Songtao Li, Lixin Na, Rennan Feng, Liyan Liu, Ying Li, Changhao Sun. Mangiferin decreases plasma free fatty acids through promoting its catabolism in liver by activation of AMPK.
PloS one.
2012; 7(1):e30782. doi:
10.1371/journal.pone.0030782. [PMID: 22292039] - Thiago Martins Batista, Lilian Midori Tomiyoshi, Ana Carolina Dias, Letícia Prates Roma, Carolina Maria Módulo, Leonardo Tannus Malki, Elísio Bueno Machado Filho, Rafael Deminice, Alceu Afonso Jordão, Daniel A Cunha, Eduardo Melani Rocha. Age-dependent changes in rat lacrimal gland anti-oxidant and vesicular related protein expression profiles.
Molecular vision.
2012; 18(?):194-202. doi:
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