Biphenyl (BioDeep_00000006219)

 

Secondary id: BioDeep_00000863343, BioDeep_00001867622

human metabolite Volatile Flavor Compounds


代谢物信息卡片


Aromatic hydrocarbons, biphenyl-rich

化学式: C12H10 (154.078246)
中文名称: 联苯
谱图信息: 最多检出来源 Homo sapiens(blood) 0.53%

分子结构信息

SMILES: C1=CC=C(C=C1)C1=CC=CC=C1
InChI: InChI=1S/C12H10/c1-3-7-11(8-4-1)12-9-5-2-6-10-12/h1-10H

描述信息

Fungistat, especies for citrus fruits. It is used as food preservative and flavouring agent. Detected in bilberry, wine grape, carrot, peas, rum, potato, bell pepper, tomato, butter, milk, smoked fatty fish, cocoa, coffee, roast peanuts, olive, buckwheat and tamarind. Generally, the fruit packaging is impregnated with biphenyl, which evaporates into the air space surrounding the fruit. Some biphenyl is absorbed by the fruit skins. Biphenyl is found in many foods, some of which are lovage, carrot, alcoholic beverages, and nuts.
Biphenyl is found in alcoholic beverages. Fungistat, especially for citrus fruits. Biphenyl is used as food preservative and flavouring agent. Biphenyl is detected in bilberry, wine grape, carrot, peas, rum, potato, bell pepper, tomato, butter, milk, smoked fatty fish, cocoa, coffee, roast peanuts, olive, buckwheat and tamarind. Generally, the fruit packaging is impregnated with biphenyl, which evaporates into the air space surrounding the fruit. Some biphenyl is absorbed by the fruit skin
D016573 - Agrochemicals
D010575 - Pesticides

同义名列表

24 个代谢物同义名

Aromatic hydrocarbons, biphenyl-rich; 1,1-Biphenyl, butenylated; Butenylated 1,1-biphenyl; Diphenyl, 14C-labeled; 1,1-Biphenyl, 9ci; Biphenyl-ul-14C; Phenylbenzene; 1, 1-Diphenyl; 1,1-Biphenyl; 1,1-Diphenyl; Tetrosin ly; Phenador-X; Carolid al; Bibenzene; FEMA 3129; Biphenyl; Lemonene; Diphenyl; Xenene; PHPH; e230; BNL; Biphenyl; Biphenyl



数据库引用编号

23 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

1 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(1)

  • biphenyl degradation: H+ + NADH + O2 + biphenyl ⟶ NAD+ + cis-3-phenylcyclohexa-3,5-diene-1,2-diol

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

5 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Ya-Ling Yu, Yi-Wen Wu, Yan-Hua Jiao, Fang-Ming Liu, Bin Wang, Jun Cao, Li-Hong Ye. Nontargeted metabolomics and enzyme inhibitory and antioxidant activities for chemical and biological characterization of jujube (Ziziphus jujuba) extracts. Journal of pharmaceutical and biomedical analysis. 2024 May; 242(?):116040. doi: 10.1016/j.jpba.2024.116040. [PMID: 38387129]
  • Tasnia Sharin, Lucas J Leinen, David Schreiber, Vaille A Swenson, Sarah A Emsley, E Jamie Trammell, Patrick Videau, Doug Crump, Michael O Gaylor. Description of Solvent-Extractable Chemicals in Thermal Receipts and Toxicological Assessment of Bisphenol S and Diphenyl Sulfone. Bulletin of environmental contamination and toxicology. 2024 Apr; 112(4):63. doi: 10.1007/s00128-024-03871-4. [PMID: 38615298]
  • Ayano Kobayashi, Yohei Saito, Katsunori Miyake, Shuichi Fukuyoshi, David J Newman, Barry R O'Keefe, Kuo-Hsiung Lee, Kyoko Nakagawa-Goto. Caged Xanthones and Biphenyls Isolated from the Tropical Plant Garcinia lateriflora. Journal of natural products. 2024 02; 87(2):266-275. doi: 10.1021/acs.jnatprod.3c00934. [PMID: 38251859]
  • Yuan Li, Jian Yang, Junhui Zhou, Xiufu Wan, Juan Liu, Sheng Wang, Xiaojing Ma, Lanping Guo, Zhiqiang Luo. Multi-omics revealed molecular mechanism of biphenyl phytoalexin formation in response to yeast extract-induced oxidative stress in Sorbus aucuparia suspension cells. Plant cell reports. 2024 Feb; 43(3):62. doi: 10.1007/s00299-024-03155-5. [PMID: 38336832]
  • Na-Bo Sun, Li-Jing Min, Xin-Peng Sun, Zhi-Wen Zhai, Joanna Bajsa-Hirschel, Zhe-Cheng Wei, Xue-Wen Hua, Charles L Cantrell, Hao Xu, Stephen O Duke, Xing-Hai Liu. Novel Pyrazole Acyl(thio)urea Derivatives Containing a Biphenyl Scaffold as Potential Succinate Dehydrogenase Inhibitors: Design, Synthesis, Fungicidal Activity, and SAR. Journal of agricultural and food chemistry. 2024 Feb; 72(5):2512-2525. doi: 10.1021/acs.jafc.3c07735. [PMID: 38286814]
  • Yiheng Jin, Haochun Shi, Yanbin Zhao, Jiayin Dai, Kun Zhang. Organophosphate ester cresyl diphenyl phosphate disrupts lipid homeostasis in zebrafish embryos. Environmental pollution (Barking, Essex : 1987). 2024 Feb; 342(?):123149. doi: 10.1016/j.envpol.2023.123149. [PMID: 38097162]
  • Çiğdem Bayrak, Ceren Birinci, Mehmet Kemal, Sevgi Kolayli. The Phenolic Composition and Antioxidant Properties of Figs (Ficus carica L.) Grown in the Black Sea Region. Plant foods for human nutrition (Dordrecht, Netherlands). 2023 Sep; 78(3):539-545. doi: 10.1007/s11130-023-01089-z. [PMID: 37605067]
  • Jianfa Wu, Lei Li, Chang Liu, Chunyi Li, Ying Cui, Weixing Ding, Jing Zhang, Leiling Shi. Two New Compounds from Allii Macrostemonis Bulbus and Their In Vitro Antioxidant Activities. Molecules (Basel, Switzerland). 2023 Aug; 28(17):. doi: 10.3390/molecules28176176. [PMID: 37687005]
  • Xin Kang, Xiaoxiang Zhao, Xinshan Song. Analysis of a novel strain Brevundimonas KX-1 capable of degrading 3-chlorocarbazole based on the whole genome sequence. Antonie van Leeuwenhoek. 2023 Jun; 116(6):577-593. doi: 10.1007/s10482-023-01831-2. [PMID: 37186067]
  • Oana Mihaela Neagu, Timea Ghitea, Eleonora Marian, Laurian Vlase, Ana-Maria Vlase, Gabriela Ciavoi, Pálma Fehér, Annamária Pallag, Ildikó Bácskay, Dániel Nemes, Laura Grațiela Vicaș, Alin Teușdea, Tünde Jurca. Formulation and Characterization of Mucoadhesive Polymeric Films Containing Extracts of Taraxaci Folium and Matricariae Flos. Molecules (Basel, Switzerland). 2023 May; 28(10):. doi: 10.3390/molecules28104002. [PMID: 37241746]
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  • Kandrakonda Yelamanda Rao, Shaik Jeelan Basha, Kallubai Monika, Navya Naidu Gajula, Irla Sivakumar, Sandeep Kumar, Ramakrishna Vadde, Bindu Madhava Reddy Aramati, Rajagopal Subramanyam, Amooru Gangaiah Damu. Development of quinazolinone and vanillin acrylamide hybrids as multi-target directed ligands against Alzheimer's disease and mechanistic insights into their binding with acetylcholinesterase. Journal of biomolecular structure & dynamics. 2023 Apr; ?(?):1-18. doi: 10.1080/07391102.2023.2203255. [PMID: 37098803]
  • Xianzhi Chai, Bohan Li, Chi Chen, Weijian Zhang, Lulu Sun, Hai-Hao Han, Yafei Zhang, Shasha Sun, Jianming Yang, Junji Zhang, Xiao-Peng He. A Highly Sensitive and Selective Near-Infrared Fluorescent Probe for Imaging Peroxynitrite in Living Cells and Drug-Induced Liver Injury Mice. Analytical chemistry. 2023 04; 95(13):5747-5753. doi: 10.1021/acs.analchem.3c00007. [PMID: 36951754]
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  • Xiao-Jia Liu, Tian-Meng Lv, Sheng Sun, Jing-Yi Xu, Qi Guan, Jia-Hui Hao, Zhen-Chi Zhou, Sheng-Li Niu, Hui-Ming Hua. Apoptotic effects of phenols from the twigs and leaves of Garcinia nujiangensis. Fitoterapia. 2023 Jan; 166(?):105435. doi: 10.1016/j.fitote.2023.105435. [PMID: 36731607]
  • Run-Xin Liu, Yan-Ni Liang, Xuan-Xuan Ren, Qian-Qian Wu, Can Huang, Shi-Nian Cao, Yu Wan, Sheng-Liang Zhou, Rui Yuan, Hui Wu. Synthesis and Antibacterial Activity of Spiro[4H-pyran-3,3'-oxindoles] Catalyzed by Tröger's Base Derivative. Current organic synthesis. 2023; 20(8):870-879. doi: 10.2174/1570179419666220614142611. [PMID: 35702794]
  • Sevil Albayrak, Ahmet Aksoy. Comparative analysis of phenolic compositions and biological activities of three endemic Teucrium L. (Lamiaceae) species from Turkey. Anais da Academia Brasileira de Ciencias. 2023; 95(1):e20220184. doi: 10.1590/0001-3765202320220184. [PMID: 37162086]
  • Francesco Siano, Gianluca Picariello, Domenico Castaldo, Domenico Cautela, Tonino Caruso, Ermanno Vasca. Monitoring antioxidants by coulometry: Quantitative assessment of the strikingly high antioxidant capacity of bergamot (Citrus bergamia R.) by-products. Talanta. 2023 Jan; 251(?):123765. doi: 10.1016/j.talanta.2022.123765. [PMID: 35931010]
  • Denis A Babkov, Olga N Zhukovskaya, Anastasia A Brigadirova, Diana R Prilepskaya, Alexandra A Kolodina, Abbas Haider S Abbas, Anatolii S Morkovnik, M Elizabeth Sobhia, Ketan Ghosh, Alexander A Spasov. Discovery and evaluation of biphenyl derivatives of 2-iminobenzimidazoles as prototype dual PTP1B inhibitors and AMPK activators with in vivo antidiabetic activity. Chemical biology & drug design. 2022 Dec; ?(?):. doi: 10.1111/cbdd.14198. [PMID: 36546307]
  • Yue Lv, Chengzhao Li, Ze Wang, Qilan Wang, Gang Li, Jun Dang. Preparative isolation of antioxidative furanocoumarins from Dracocephalum heterophyllum and their potential action target. Journal of separation science. 2022 Dec; 45(24):4375-4387. doi: 10.1002/jssc.202200309. [PMID: 36222230]
  • Najeebah Az-Zahra Tashim, Syazana Abdullah Lim, Aida Maryam Basri. Synergistic antioxidant activity of selected medicinal plants in Brunei Darussalam and its application in developing fortified pasta. Journal of the science of food and agriculture. 2022 Dec; 102(15):7331-7342. doi: 10.1002/jsfa.12099. [PMID: 35767363]
  • Chuang Liu, Yuqing Lei, Gang Li, Chen Yuan, Yue Lv, Song Yu, Yun Shao, Jun Dang. Three new dihydroflavonols with free radical scavenging activity from Ribes himalense Royle ex Decne. Natural product research. 2022 Nov; 36(21):5490-5498. doi: 10.1080/14786419.2021.2017929. [PMID: 34935575]
  • Jun Dang, Yue Lv, Chengzhao Li, Yan Fang, Gang Li, Qilan Wang. Integrated chromatographic approach for the discovery of gingerol antioxidants from Dracocephalum heterophyllum and their potential targets. Analytical methods : advancing methods and applications. 2022 10; 14(41):4133-4145. doi: 10.1039/d2ay01282k. [PMID: 36226573]
  • Basim R Al Shammari. Antioxidant, Antimicrobial and In Silico NADPH Oxidase Inhibition of Chemically-Analyzed Essential Oils Derived from Ballota deserti (Noë) Jury. Molecules (Basel, Switzerland). 2022 Oct; 27(19):. doi: 10.3390/molecules27196636. [PMID: 36235177]
  • Fatima Zahra Kamal, Radu Lefter, Cosmin-Teodor Mihai, Hanane Farah, Alin Ciobica, Ahmad Ali, Iulian Radu, Ioannis Mavroudis, Abdellah Ech-Chahad. Chemical Composition, Antioxidant and Antiproliferative Activities of Taraxacum officinale Essential Oil. Molecules (Basel, Switzerland). 2022 Oct; 27(19):. doi: 10.3390/molecules27196477. [PMID: 36235013]
  • Awadalgeed M A Hassan, Oscar Zannou, Hojjat Pashazadeh, Ali Ali Redha, Ilkay Koca. Drying date plum (Diospyros lotus L.) fruit: Assessing rehydration properties, antioxidant activity, and phenolic compounds. Journal of food science. 2022 Oct; 87(10):4394-4415. doi: 10.1111/1750-3841.16322. [PMID: 36112569]
  • Pimmada Junsathian, Soichiro Nakamura, Shigeru Katayama, Saroat Rawdkuen. Antioxidant and Antimicrobial Activities of Thai Edible Plant Extracts Prepared Using Different Extraction Techniques. Molecules (Basel, Switzerland). 2022 Oct; 27(19):. doi: 10.3390/molecules27196489. [PMID: 36235025]
  • Mohammad Amil Zulhilmi Benjamin, Shean Yeaw Ng, Fiffy Hanisdah Saikim, Nor Azizun Rusdi. The Effects of Drying Techniques on Phytochemical Contents and Biological Activities on Selected Bamboo Leaves. Molecules (Basel, Switzerland). 2022 Sep; 27(19):. doi: 10.3390/molecules27196458. [PMID: 36234995]
  • Hla Myo, Nuntawat Khat-Udomkiri. Optimization of ultrasound-assisted extraction of bioactive compounds from coffee pulp using propylene glycol as a solvent and their antioxidant activities. Ultrasonics sonochemistry. 2022 Sep; 89(?):106127. doi: 10.1016/j.ultsonch.2022.106127. [PMID: 36007328]
  • Siwattra Choodej, Kedkarn Koopklang, Achara Raksat, Natthaya Chuaypen, Khanitha Pudhom. Bioactive xanthones, benzophenones and biphenyls from mangosteen root with potential anti-migration against hepatocellular carcinoma cells. Scientific reports. 2022 05; 12(1):8605. doi: 10.1038/s41598-022-12507-8. [PMID: 35597781]
  • Rongyan Yang, Xiao Wang, Jingwen Wang, Pengyu Chen, Qing Liu, Wenjue Zhong, Lingyan Zhu. Insights into the sex-dependent reproductive toxicity of 2-ethylhexyl diphenyl phosphate on zebrafish (Danio rerio). Environment international. 2022 01; 158(?):106928. doi: 10.1016/j.envint.2021.106928. [PMID: 34638023]
  • Temitope Adelusi, Xizhi Li, Liu Xu, Lei Du, Meng Hao, Xueyan Zhou, Apu Chowdhry, Ying Sun, Xiaoke Gu, Qian Lu, Xiaoxing Yin. Novel Chalcone BDD-39 Mitigated Diabetic Nephropathy through the Activation of Nrf2/ARE Signaling. Current molecular pharmacology. 2022; 15(4):658-675. doi: 10.2174/1874467214666210915145104. [PMID: 34525927]
  • Belnaser A Busnena, Till Beuerle, Felix Mahnkopp-Dirks, Traud Winkelmann, Ludger Beerhues, Benye Liu. Formation and exudation of biphenyl and dibenzofuran phytoalexins by roots of the apple rootstock M26 grown in apple replant disease soil. Phytochemistry. 2021 Dec; 192(?):112972. doi: 10.1016/j.phytochem.2021.112972. [PMID: 34624729]
  • Shih-Yao Lin, Asif Hameed, Chia-Fang Tsai, Chiu-Chung Young. Zeimonas arvi gen. nov., sp. nov., of the family Burkholderiaceae, harboring biphenyl- and phenolic acid-metabolizing genes, isolated from a long-term ecological research field. Antonie van Leeuwenhoek. 2021 Dec; 114(12):2101-2111. doi: 10.1007/s10482-021-01664-x. [PMID: 34599477]
  • Tao Chen, Wen-Qin Li, Zheng Liu, Wen Jiang, Tian Liu, Qing Yang, Xiao-Lei Zhu, Guang-Fu Yang. Discovery of Biphenyl-Sulfonamides as Novel β-N-Acetyl-d-Hexosaminidase Inhibitors via Structure-Based Virtual Screening. Journal of agricultural and food chemistry. 2021 Oct; 69(40):12039-12047. doi: 10.1021/acs.jafc.1c01642. [PMID: 34587743]
  • Chiramet Auranwiwat, Thunwadee Limtharakul, Stephen G Pyne, Roonglawan Rattanajak, Sumalee Kamchonwongpaisan. A new xanthone and a biphenyl from the flower and twig extracts of Garcinia mckeaniana. Natural product research. 2021 Oct; 35(20):3404-3409. doi: 10.1080/14786419.2019.1700505. [PMID: 31842629]
  • Yichao Wu, Yuanyuan Jiang, Li Zhang, Jing Zhou, Yan Yu, Yonghong Zhou, Tairan Kang. Chemical Profiling and Antioxidant Evaluation of Paeonia lactiflora Pall. "Zhongjiang" by HPLC-ESI-MS Combined with DPPH Assay. Journal of chromatographic science. 2021 Sep; 59(9):795-805. doi: 10.1093/chromsci/bmab005. [PMID: 33558884]
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