Adenosine 2,5-bisphosphate (BioDeep_00000005330)

   


代谢物信息卡片


adenosine-2,5-bisphosphate

化学式: C10H15N5O10P2 (427.0294)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)OP(=O)(O)O)N
InChI: InChI=1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(25-27(20,21)22)6(16)4(24-10)1-23-26(17,18)19/h2-4,6-7,10,16H,1H2,(H2,11,12,13)(H2,17,18,19)(H2,20,21,22)/t4-,6-,7-,10-/m1/s1



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 AHSP, AKR1C3, ANXA5, CDC42, G6PD, NOS1, NOS2, NOS3, PIK3R6, SYK
Peripheral membrane protein 6 ANXA5, CYP1B1, G6PD, HSD17B6, NOS1, PIK3R6
Endoplasmic reticulum membrane 2 CDC42, CYP1B1
Nucleus 5 AKR1C3, NOS1, NOS2, NOS3, SYK
cytosol 9 AKR1C3, ANXA5, CDC42, G6PD, NOS1, NOS2, NOS3, PIK3R6, SYK
dendrite 1 P2RY1
phagocytic vesicle 1 CDC42
centrosome 1 CDC42
nucleoplasm 3 NOS1, NOS2, NOS3
Cell membrane 8 ADRB3, CDC42, ITGAM, P2RX1, P2RY1, P2RY12, PIK3R6, SYK
Lipid-anchor 1 CDC42
Cytoplasmic side 1 CDC42
Early endosome membrane 1 HSD17B6
Multi-pass membrane protein 5 ADRB3, NNT, P2RX1, P2RY1, P2RY12
Synapse 1 NOS1
cell surface 3 ITGAM, P2RY1, P2RY12
glutamatergic synapse 3 CDC42, P2RX1, P2RY1
Golgi apparatus 1 NOS3
Golgi membrane 2 CDC42, NOS3
mitochondrial inner membrane 1 NNT
neuronal cell body 1 CDC42
postsynapse 1 P2RX1
sarcolemma 2 ANXA5, NOS1
Cytoplasm, cytosol 3 G6PD, NOS2, SYK
plasma membrane 12 ADRB3, CDC42, ITGAM, KNG1, NOS1, NOS2, NOS3, P2RX1, P2RY1, P2RY12, PIK3R6, SYK
Membrane 9 ANXA5, CDC42, CYP1B1, G6PD, ITGAM, NNT, P2RX1, P2RY12, PIK3R6
apical plasma membrane 1 P2RY1
basolateral plasma membrane 1 P2RY1
caveola 1 NOS3
extracellular exosome 6 AKR1C3, ANXA5, CDC42, G6PD, ITGAM, KNG1
Lumenal side 1 HSD17B6
endoplasmic reticulum 1 HSD17B6
extracellular space 3 CCL17, ITGAM, KNG1
perinuclear region of cytoplasm 3 NOS1, NOS2, NOS3
Schaffer collateral - CA1 synapse 1 CDC42
mitochondrion 3 CYP1B1, NNT, NOS1
protein-containing complex 4 CDC42, NOS1, P2RX1, SYK
intracellular membrane-bounded organelle 3 CYP1B1, G6PD, HSD17B6
Microsome membrane 2 CYP1B1, HSD17B6
filopodium 1 CDC42
postsynaptic density 2 NOS1, P2RY1
Single-pass type I membrane protein 1 ITGAM
Secreted 1 CCL17
extracellular region 3 ANXA5, CCL17, KNG1
cytoplasmic side of plasma membrane 1 G6PD
centriolar satellite 1 G6PD
photoreceptor inner segment 1 NOS1
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 CDC42
external side of plasma membrane 3 ANXA5, ITGAM, P2RX1
dendritic spine 2 CDC42, NOS1
midbody 1 CDC42
Cytoplasm, P-body 2 NOS2, NOS3
P-body 2 NOS2, NOS3
apical part of cell 1 CDC42
cell-cell junction 1 CDC42
spindle midzone 1 CDC42
postsynaptic membrane 2 P2RX1, P2RY1
presynaptic active zone membrane 2 P2RX1, P2RY1
Cell membrane, sarcolemma 1 NOS1
Cytoplasm, perinuclear region 2 NOS1, NOS2
Mitochondrion inner membrane 1 NNT
Matrix side 1 NNT
Membrane raft 3 ITGAM, NOS1, P2RX1
Cytoplasm, cytoskeleton, spindle 1 CDC42
focal adhesion 2 ANXA5, CDC42
Peroxisome 1 NOS2
sarcoplasmic reticulum 1 NOS1
peroxisomal matrix 1 NOS2
Cell projection, dendritic spine 1 NOS1
collagen-containing extracellular matrix 2 ANXA5, KNG1
secretory granule 1 CDC42
receptor complex 1 ADRB3
Zymogen granule membrane 1 ANXA5
neuron projection 1 CDC42
cilium 1 P2RY1
cell periphery 1 NOS1
mitotic spindle 1 CDC42
cytoskeleton 2 NOS1, NOS3
cytoplasmic ribonucleoprotein granule 1 CDC42
Secreted, extracellular space 1 KNG1
blood microparticle 1 KNG1
leading edge membrane 1 CDC42
Cell projection, dendrite 1 CDC42
specific granule membrane 2 ITGAM, P2RX1
tertiary granule membrane 1 ITGAM
Cytoplasm, Stress granule 1 NOS3
cytoplasmic stress granule 1 NOS3
respiratory chain complex 1 NNT
cell body 1 P2RY1
plasma membrane raft 1 ITGAM
secretory granule membrane 1 P2RX1
endoplasmic reticulum lumen 1 KNG1
platelet alpha granule lumen 1 KNG1
phosphatidylinositol 3-kinase complex 1 PIK3R6
phosphatidylinositol 3-kinase complex, class IA 1 PIK3R6
endocytic vesicle membrane 1 NOS3
vesicle membrane 1 ANXA5
early phagosome 1 SYK
integrin complex 1 ITGAM
hemoglobin complex 1 AHSP
T cell receptor complex 1 SYK
cortical cytoskeleton 1 NOS2
integrin alphaM-beta2 complex 1 ITGAM
endothelial microparticle 1 ANXA5
B cell receptor complex 1 SYK
cell body membrane 1 P2RY12
cell projection membrane 1 P2RY12
phosphatidylinositol 3-kinase complex, class IB 1 PIK3R6
Golgi transport complex 1 CDC42
storage vacuole 1 CDC42


文献列表

  • Mario Milani, Emanuela Balconi, Alessandro Aliverti, Eloise Mastrangelo, Frank Seeber, Martino Bolognesi, Giuliana Zanetti. Ferredoxin-NADP+ reductase from Plasmodium falciparum undergoes NADP+-dependent dimerization and inactivation: functional and crystallographic analysis. Journal of molecular biology. 2007 Mar; 367(2):501-13. doi: 10.1016/j.jmb.2007.01.005. [PMID: 17258767]
  • E Camaioni, J L Boyer, A Mohanram, T K Harden, K A Jacobson. Deoxyadenosine bisphosphate derivatives as potent antagonists at P2Y1 receptors. Journal of medicinal chemistry. 1998 Jan; 41(2):183-90. doi: 10.1021/jm970433l. [PMID: 9457242]
  • J L Boyer, T Romero-Avila, J B Schachter, T K Harden. Identification of competitive antagonists of the P2Y1 receptor. Molecular pharmacology. 1996 Nov; 50(5):1323-9. doi: . [PMID: 8913364]