6-Methoxymellein (BioDeep_00000004911)

 

Secondary id: BioDeep_00001868774

human metabolite


代谢物信息卡片


6-Methoxy-8-hydroxy-3-methyl-3,4-dihydroisocoumarin, (R)-(-)-isomer

化学式: C11H12O4 (208.0735552)
中文名称:
谱图信息: 最多检出来源 Viridiplantae(plant) 0.04%

分子结构信息

SMILES: c1c(cc2c(c1O)C(=O)O[C@@H](C2)C)OC
InChI: InChI=1S/C11H12O4/c1-6-3-7-4-8(14-2)5-9(12)10(7)11(13)15-6/h4-6,12H,3H2,1-2H3

描述信息

Isolated from Aspergillus caespitosus, Aspergillus variecolor and Sporormia bipartis. Reaches fungitoxic levels in stored infected carrot. Shows broad antimicrobial action. 6-Methoxymellein is found in wild carrot, root vegetables, and carrot.
6-Methoxymellein is found in carrot. 6-Methoxymellein is isolated from Aspergillus caespitosus, Aspergillus variecolor and Sporormia bipartis. Reaches fungitoxic levels in stored infected carrot. Shows broad antimicrobial action.

同义名列表

12 个代谢物同义名

6-Methoxy-8-hydroxy-3-methyl-3,4-dihydroisocoumarin, (R)-(-)-isomer; 3,4-dihydro-8-Hydroxy-6-methoxy-3-methyl-1H-2-benzopyran-1-one; 8-hydroxy-6-methoxy-3-methyl-3,4-dihydro-1H-2-benzopyran-1-one; 2,4-Dihydro-8-hydroxy-6-methoxy-3-methyl-1H-2-benzopyran-1-one; 3,4-Dihydro-8-hydroxy-6-methoxy-3-methylisocoumarin; 3-Methyl-6-methoxy-8-hydroxy-3,4-dihydroisocoumarin; 6-Methoxy-8-hydroxy-3-methyl-3,4-dihydroisocoumarin; Antibiotic LL-N313a; 6-Mhmd-isocoumarin; 6-Methoxymellein; Isocoumarin; LL-N313a



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

2 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(1)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(1)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

15 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Alì Snene, Carmina Sirignano, Daniela Rigano, Carmen Formisano, Ridha El Mokni, Giuseppe Ercolano, Hatem Dhaouadi, Angela Ianaro, Saoussen Hammami, Orazio Taglialatela-Scafati. Antiproliferative metabolites from the Northern African endemic plant Daucus virgatus (Apiaceae). Phytochemistry. 2017 Nov; 143(?):194-198. doi: 10.1016/j.phytochem.2017.08.010. [PMID: 28843162]
  • Randi Seljåsen, Gjermund Vogt, Elisabeth Olsen, Per Lea, Lars Arne Høgetveit, Torgeir Tajet, Richard Meadow, Gunnar B Bengtsson. Influence of field attack by carrot psyllid (Trioza apicalis Förster) on sensory quality, antioxidant capacity and content of terpenes, falcarindiol and 6-methoxymellein of carrots (Daucus carota L.). Journal of agricultural and food chemistry. 2013 Mar; 61(11):2831-8. doi: 10.1021/jf303979y. [PMID: 23414489]
  • Sébastien Louarn, Arkadiusz Nawrocki, Merete Edelenbos, Dan F Jensen, Ole N Jensen, David B Collinge, Birgit Jensen. The influence of the fungal pathogen Mycocentrospora acerina on the proteome and polyacetylenes and 6-methoxymellein in organic and conventionally cultivated carrots (Daucus carota) during post harvest storage. Journal of proteomics. 2012 Jan; 75(3):962-77. doi: 10.1016/j.jprot.2011.10.014. [PMID: 22075166]
  • Ludger Schmiech, Daisuke Uemura, Thomas Hofmann. Reinvestigation of the bitter compounds in carrots (Daucus carota L.) by using a molecular sensory science approach. Journal of agricultural and food chemistry. 2008 Nov; 56(21):10252-60. doi: 10.1021/jf8023358. [PMID: 18922011]
  • Andreas Czepa, Thomas Hofmann. Quantitative studies and sensory analyses on the influence of cultivar, spatial tissue distribution, and industrial processing on the bitter off-taste of carrots (Daucus carota l.) and carrot products. Journal of agricultural and food chemistry. 2004 Jul; 52(14):4508-14. doi: 10.1021/jf0496393. [PMID: 15237959]
  • D Engelmeier, F Hadacek, O Hofer, G Lutz-Kutschera, M Nagl, G Wurz, H Greger. Antifungal 3-butylisocoumarins from Asteraceae-Anthemideae. Journal of natural products. 2004 Jan; 67(1):19-25. doi: 10.1021/np0301339. [PMID: 14738379]
  • Andreas Czepa, Thomas Hofmann. Structural and sensory characterization of compounds contributing to the bitter off-taste of carrots (Daucus carota L.) and carrot puree. Journal of agricultural and food chemistry. 2003 Jun; 51(13):3865-73. doi: 10.1021/jf034085+. [PMID: 12797757]
  • F Kurosaki, A Nishi. Stimulation of calcium influx and calcium cascade by cyclic AMP in cultured carrot cells. Archives of biochemistry and biophysics. 1993 Apr; 302(1):144-51. doi: 10.1006/abbi.1993.1192. [PMID: 8385897]