globomycin (BioDeep_00000004742)
代谢物信息卡片
globomycin
化学式: C32H57N5O9 (655.4156)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCC1C(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)O1)C(C)O)CO)C(C)CC)CC(C)C)C)C
InChI: InChI=1S/C32H57N5O9/c1-9-11-12-13-14-24-20(6)32(45)37(8)23(15-18(3)4)29(42)35-26(19(5)10-2)31(44)34-22(17-38)28(41)36-27(21(7)39)30(43)33-16-25(40)46-24/h18-24,26-27,38-39H,9-17H2,1-8H3,(H,33,43)(H,34,44)(H,35,42)(H,36,41)
描述信息
D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors
同义名列表
2 个代谢物同义名
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:5387
- KEGG: C01700
- PubChem: 115071
- Metlin: METLIN65634
- KNApSAcK: C00018183
- CAS: 64441-34-5
- CAS: 67076-74-8
- PMhub: MS000017318
- PubChem: 4840
- NIKKAJI: J152.174H
- KNApSAcK: 5387
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
- 1944 - Streptomyces halstedii: 10.7164/ANTIBIOTICS.31.426
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Nikhil Sangith, Krishnan Sankaran. Stringency of bacterial prolipoprotein signal peptidase (LspA) in recognition of signal peptides - Structure-function correlation.
Biochemical and biophysical research communications.
2017 06; 488(2):413-417. doi:
10.1016/j.bbrc.2017.05.069. [PMID: 28506828] - Véronique Viarre, Eric Cascales, Geneviève Ball, Gérard P F Michel, Alain Filloux, Romé Voulhoux. HxcQ liposecretin is self-piloted to the outer membrane by its N-terminal lipid anchor.
The Journal of biological chemistry.
2009 Dec; 284(49):33815-23. doi:
10.1074/jbc.m109.065938. [PMID: 19815547] - Isabelle Leduc, Patricia Richards, Crystal Davis, Birgit Schilling, Christopher Elkins. A novel lectin, DltA, is required for expression of a full serum resistance phenotype in Haemophilus ducreyi.
Infection and immunity.
2004 Jun; 72(6):3418-28. doi:
10.1128/iai.72.6.3418-3428.2004. [PMID: 15155648] - D A Haake, C Martinich, T A Summers, E S Shang, J D Pruetz, A M McCoy, M K Mazel, C A Bolin. Characterization of leptospiral outer membrane lipoprotein LipL36: downregulation associated with late-log-phase growth and mammalian infection.
Infection and immunity.
1998 Apr; 66(4):1579-87. doi:
10.1128/iai.66.4.1579-1587.1998. [PMID: 9529084] - S Kedzierska, A Wawrzynów, A Taylor. The Rz1 gene product of bacteriophage lambda is a lipoprotein localized in the outer membrane of Escherichia coli.
Gene.
1996 Feb; 168(1):1-8. doi:
10.1016/0378-1119(95)00712-1. [PMID: 8626053] - H Bergler, D Abraham, H Aschauer, F Turnowsky. Inhibition of lipid biosynthesis induces the expression of the pspA gene.
Microbiology (Reading, England).
1994 Aug; 140 ( Pt 8)(?):1937-44. doi:
10.1099/13500872-140-8-1937. [PMID: 7921245] - N Kosic, M Sugai, C K Fan, H C Wu. Processing of lipid-modified prolipoprotein requires energy and sec gene products in vivo.
Journal of bacteriology.
1993 Oct; 175(19):6113-7. doi:
10.1128/jb.175.19.6113-6117.1993. [PMID: 8407783] - B Oudega, D Clark, F Stegehuis, M J Majoor, J Luirink. A lipoprotein signal peptide plus a cysteine residue at the amino-terminal end of the periplasmic protein beta-lactamase is sufficient for its lipid modification, processing and membrane localization in Escherichia coli.
FEMS microbiology letters.
1993 Apr; 108(3):353-9. doi:
10.1111/j.1574-6968.1993.tb06127.x. [PMID: 8514122] - R Schneider, K Hantke. Iron-hydroxamate uptake systems in Bacillus subtilis: identification of a lipoprotein as part of a binding protein-dependent transport system.
Molecular microbiology.
1993 Apr; 8(1):111-21. doi:
10.1111/j.1365-2958.1993.tb01208.x. [PMID: 8388528] - L F Erdile, M A Brandt, D J Warakomski, G J Westrack, A Sadziene, A G Barbour, J P Mays. Role of attached lipid in immunogenicity of Borrelia burgdorferi OspA.
Infection and immunity.
1993 Jan; 61(1):81-90. doi:
10.1128/iai.61.1.81-90.1993. [PMID: 8418068] - W Y Zhang, M Inouye, H C Wu. Neither lipid modification nor processing of prolipoprotein is essential for the formation of murein-bound lipoprotein in Escherichia coli.
The Journal of biological chemistry.
1992 Sep; 267(27):19631-5. doi:
. [PMID: 1527082] - M S Hanson, E J Hansen. Molecular cloning, partial purification, and characterization of a haemin-binding lipoprotein from Haemophilus influenzae type b.
Molecular microbiology.
1991 Feb; 5(2):267-78. doi:
10.1111/j.1365-2958.1991.tb02107.x. [PMID: 2041470] - M A Swancutt, J D Radolf, M V Norgard. The 34-kilodalton membrane immunogen of Treponema pallidum is a lipoprotein.
Infection and immunity.
1990 Feb; 58(2):384-92. doi:
10.1128/iai.58.2.384-392.1990. [PMID: 2404869] - D Cavard, S P Howard, R Lloubes, C Lazdunski. High-level expression of the colicin A lysis protein.
Molecular & general genetics : MGG.
1989 Jun; 217(2-3):511-9. doi:
10.1007/bf02464925. [PMID: 2505057] - J Luirink, D M Clark, J Ras, E J Verschoor, F Stegehuis, F K de Graaf, B Oudega. pCloDF13-encoded bacteriocin release proteins with shortened carboxyl-terminal segments are lipid modified and processed and function in release of cloacin DF13 and apparent host cell lysis.
Journal of bacteriology.
1989 May; 171(5):2673-9. doi:
10.1128/jb.171.5.2673-2679.1989. [PMID: 2651413] - K Sakka, T Watanabe, R Beers, H C Wu. Isolation and characterization of a new globomycin-resistant dnaE mutant of Escherichia coli.
Journal of bacteriology.
1987 Aug; 169(8):3400-8. doi:
10.1128/jb.169.8.3400-3408.1987. [PMID: 3112119] - D Cavard, D Baty, S P Howard, H M Verheij, C Lazdunski. Lipoprotein nature of the colicin A lysis protein: effect of amino acid substitutions at the site of modification and processing.
Journal of bacteriology.
1987 May; 169(5):2187-94. doi:
10.1128/jb.169.5.2187-2194.1987. [PMID: 3571165] - M Hussain, J O Lampen. Accumulation of glyceride-modified pre-penicillinase of Bacillus licheniformis in Escherichia coli treated with globomycin.
FEBS letters.
1983 Jun; 157(1):31-6. doi:
10.1016/0014-5793(83)81110-7. [PMID: 6345194] - H C Wu, J S Lai, S Hayashi, C Z Giam. Biogenesis of membrane lipoproteins in Escherichia coli.
Biophysical journal.
1982 Jan; 37(1):307-15. doi:
10.1016/s0006-3495(82)84679-1. [PMID: 6459805] - J B Nielsen, M P Caulfield, J O Lampen. Lipoprotein nature of Bacillus licheniformis membrane penicillinase.
Proceedings of the National Academy of Sciences of the United States of America.
1981 Jun; 78(6):3511-5. doi:
10.1073/pnas.78.6.3511. [PMID: 7022453]
