pregnane (BioDeep_00000004703)

 

Secondary id: BioDeep_00001869519

human metabolite natural product


代谢物信息卡片


17-ethyl-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene

化学式: C21H36 (288.2817)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(plant) 26.47%

分子结构信息

SMILES: CCC1CCC2C1(CCC3C2CCC4C3(CCCC4)C)C
InChI: InChI=1S/C21H36/c1-4-15-9-11-18-17-10-8-16-7-5-6-13-20(16,2)19(17)12-14-21(15,18)3/h15-19H,4-14H2,1-3H3

描述信息

同义名列表

6 个代谢物同义名

17-ethyl-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene; 5beta-Pregnanediol; 5b-pregnanediol; D4 PREGNANE; pregnane; Pregnane



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

10 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ABCB1, AR, BDNF, CYP2B6, CYP2C9, CYP3A4, MSMP, NR1I3, VDR
Peripheral membrane protein 2 ACHE, CYP2B6
Endoplasmic reticulum membrane 4 CYP1A2, CYP2B6, CYP2C9, CYP3A4
Nucleus 7 ACHE, AR, MPO, NR1H4, NR1I2, NR1I3, VDR
cytosol 3 AR, NR1I3, VDR
dendrite 1 BDNF
nuclear body 1 NR1I2
nucleoplasm 6 AR, MPO, NR1H4, NR1I2, NR1I3, VDR
RNA polymerase II transcription regulator complex 2 NR1H4, VDR
Cell membrane 3 ABCB1, ACHE, TNF
Multi-pass membrane protein 1 ABCB1
Synapse 1 ACHE
cell surface 3 ABCB1, ACHE, TNF
Golgi apparatus 1 ACHE
Golgi membrane 1 INS
lysosomal membrane 1 GAA
neuromuscular junction 1 ACHE
neuronal cell body 1 TNF
synaptic vesicle 1 BDNF
Lysosome 2 GAA, MPO
plasma membrane 8 ABCB1, ACHE, AR, BCHE, CYP2C9, GAA, KNG1, TNF
Membrane 6 ABCB1, ACHE, AR, BDNF, CYP3A4, GAA
apical plasma membrane 1 ABCB1
axon 1 BDNF
extracellular exosome 4 ABCB1, GAA, KNG1, MPO
Lysosome membrane 1 GAA
extracellular space 9 ACHE, BCHE, BDNF, IL6, INS, KNG1, MPO, MSMP, TNF
lysosomal lumen 1 GAA
perinuclear region of cytoplasm 2 ACHE, BDNF
protein-containing complex 1 AR
intracellular membrane-bounded organelle 6 CYP1A2, CYP2B6, CYP2C9, CYP3A4, GAA, MPO
Microsome membrane 4 CYP1A2, CYP2B6, CYP2C9, CYP3A4
Secreted 7 ACHE, BCHE, BDNF, GAA, IL6, INS, MSMP
extracellular region 9 ACHE, BCHE, BDNF, GAA, IL6, INS, KNG1, MPO, TNF
Extracellular side 1 ACHE
transcription regulator complex 1 NR1I2
external side of plasma membrane 1 TNF
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Apical cell membrane 1 ABCB1
Membrane raft 1 TNF
Cytoplasm, cytoskeleton 1 NR1I3
basement membrane 1 ACHE
collagen-containing extracellular matrix 1 KNG1
secretory granule 1 MPO
nuclear speck 1 AR
receptor complex 2 NR1H4, VDR
chromatin 5 AR, NR1H4, NR1I2, NR1I3, VDR
phagocytic cup 1 TNF
cytoskeleton 1 NR1I3
[Isoform 3]: Nucleus 1 NR1H4
Secreted, extracellular space 1 KNG1
blood microparticle 2 BCHE, KNG1
Lipid-anchor, GPI-anchor 1 ACHE
endosome lumen 1 INS
tertiary granule membrane 1 GAA
euchromatin 1 NR1H4
side of membrane 1 ACHE
intermediate filament cytoskeleton 1 NR1I2
azurophil granule 1 MPO
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 5 BCHE, BDNF, IL6, INS, KNG1
platelet alpha granule lumen 1 KNG1
transport vesicle 1 INS
azurophil granule membrane 1 GAA
azurophil granule lumen 1 MPO
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
nuclear envelope lumen 1 BCHE
phagocytic vesicle lumen 1 MPO
[Isoform 2]: Nucleus 1 NR1H4
[Isoform 1]: Nucleus 1 NR1H4
synaptic cleft 1 ACHE
ficolin-1-rich granule membrane 1 GAA
external side of apical plasma membrane 1 ABCB1
[Isoform 4]: Nucleus 1 NR1H4
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
interleukin-6 receptor complex 1 IL6
autolysosome lumen 1 GAA
[Isoform H]: Cell membrane 1 ACHE
[Neurotrophic factor BDNF precursor form]: Secreted 1 BDNF
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Rodrigo Aguilera, Thomas E Chapman, Henrique Pereira, Giselle C Oliveira, Renata P Illanes, Telma F Fernandes, Débora A Azevedo, Francisco Aquino Neto. Drug testing data from the 2007 Pan American Games: delta13C values of urinary androsterone, etiocholanolone and androstanediols determined by GC/C/IRMS. The Journal of steroid biochemistry and molecular biology. 2009 Jul; 115(3-5):107-14. doi: 10.1016/j.jsbmb.2009.03.012. [PMID: 19428237]
  • Ying Zhang, Herbert J Tobias, J Thomas Brenna. Steroid isotopic standards for gas chromatography-combustion isotope ratio mass spectrometry (GCC-IRMS). Steroids. 2009 Mar; 74(3):369-78. doi: 10.1016/j.steroids.2008.10.001. [PMID: 18992268]
  • F J Bradshaw, E J Stead-Richardson, A J Reeder, J E Oates, S D Bradshaw. Reproductive activity in captive female Honey possums, Tarsipes rostratus, assessed by faecal steroid analysis. General and comparative endocrinology. 2004 Aug; 138(1):20-31. doi: 10.1016/j.ygcen.2004.04.008. [PMID: 15242748]