Sedoheptulose 1,7-bisphosphate (BioDeep_00000004431)

 

Secondary id: BioDeep_00001869551

human metabolite


代谢物信息卡片


{[(3S,4R,5R,6R)-3,4,5,6-tetrahydroxy-2-oxo-7-(phosphonooxy)heptyl]oxy}phosphonic acid

化学式: C7H16O13P2 (370.0066)
中文名称:
谱图信息: 最多检出来源 Rattus norvegicus(otcml) 9.01%

分子结构信息

SMILES: C(C(C(C(C(C(=O)COP(=O)(O)O)O)O)O)O)OP(=O)(O)O
InChI: InChI=1S/C7H16O13P2/c8-3(1-19-21(13,14)15)5(10)7(12)6(11)4(9)2-20-22(16,17)18/h3,5-8,10-12H,1-2H2,(H2,13,14,15)(H2,16,17,18)/t3-,5-,6-,7-/m1/s1



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

4 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(4)

  • Sedoheptulose Bisphosphate Bypass: Adenosine triphosphate + D-Sedoheptulose 7-phosphate ⟶ Adenosine diphosphate + Hydrogen Ion + Sedoheptulose 1,7-bisphosphate
  • Riboneogenesis: D-Ribose 5-phosphate ⟶ D-Ribulose 5-phosphate
  • Photosynthesis: Fructose 1,6-bisphosphate + Water ⟶ Fructose 6-phosphate + Phosphate
  • Calvin-Benson Cycle: Fructose 1,6-bisphosphate + Water ⟶ Fructose 6-phosphate + Phosphate

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 ADH5, CAT, G6PD, GAPDH, GSN, TXN
Peripheral membrane protein 1 G6PD
Endoplasmic reticulum membrane 2 CYP1A2, TKT
Nucleus 3 GAPDH, PARP1, TXN
cytosol 8 ADH5, CAT, G6PD, GAPDH, GSN, PARP1, TKT, TXN
nuclear body 2 PARP1, TKT
phagocytic vesicle 1 GSN
nucleoplasm 3 PARP1, TKT, TXN
Cell membrane 1 TKT
lamellipodium 1 GSN
Multi-pass membrane protein 1 SLC7A7
Golgi membrane 1 INS
Cytoplasm, cytosol 3 G6PD, GAPDH, PARP1
plasma membrane 4 GAPDH, GSN, SLC7A7, TKT
Membrane 6 CAT, DGCR2, G6PD, GAPDH, PARP1, SLC7A7
apical plasma membrane 1 TKT
basolateral plasma membrane 1 SLC7A7
extracellular exosome 7 ADH5, CAT, G6PD, GAPDH, GSN, TKT, TXN
extracellular space 2 GSN, INS
perinuclear region of cytoplasm 1 GAPDH
mitochondrion 3 ADH5, CAT, PARP1
protein-containing complex 2 CAT, PARP1
intracellular membrane-bounded organelle 4 CAT, CYP1A2, G6PD, GAPDH
Microsome membrane 1 CYP1A2
Single-pass type I membrane protein 1 TKT
Secreted 2 INS, TXN
extracellular region 4 CAT, GSN, INS, TXN
cytoplasmic side of plasma membrane 1 G6PD
mitochondrial matrix 1 CAT
transcription regulator complex 1 PARP1
centriolar satellite 1 G6PD
nuclear membrane 1 GAPDH
actin cytoskeleton 2 GSN, TKT
microtubule cytoskeleton 1 GAPDH
nucleolus 1 PARP1
sarcoplasm 1 GSN
vesicle 2 GAPDH, TKT
Cytoplasm, perinuclear region 1 GAPDH
Cytoplasm, cytoskeleton 2 GAPDH, GSN
focal adhesion 3 CAT, GSN, TKT
Peroxisome 2 CAT, TKT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
receptor complex 1 TKT
chromatin 1 PARP1
Chromosome 1 PARP1
cytoskeleton 2 GAPDH, GSN
podosome 1 GSN
Nucleus, nucleolus 1 PARP1
nuclear replication fork 1 PARP1
chromosome, telomeric region 1 PARP1
blood microparticle 1 GSN
Basolateral cell membrane 1 SLC7A7
site of double-strand break 1 PARP1
nuclear envelope 1 PARP1
endosome lumen 1 INS
Lipid droplet 1 GAPDH
ficolin-1-rich granule lumen 2 CAT, GSN
secretory granule lumen 3 CAT, GSN, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 1 INS
cortical actin cytoskeleton 1 GSN
actin cap 1 GSN
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
ribonucleoprotein complex 1 GAPDH
protein-DNA complex 1 PARP1
GAIT complex 1 GAPDH
site of DNA damage 1 PARP1
catalase complex 1 CAT
[Poly [ADP-ribose] polymerase 1, processed N-terminus]: Chromosome 1 PARP1
[Poly [ADP-ribose] polymerase 1, processed C-terminus]: Cytoplasm 1 PARP1


文献列表

  • Laura S Garschagen, Thomas Franke, Uwe Deppenmeier. An alternative pentose phosphate pathway in human gut bacteria for the degradation of C5 sugars in dietary fibers. The FEBS journal. 2021 03; 288(6):1839-1858. doi: 10.1111/febs.15511. [PMID: 32770699]
  • Franziska Flügel, Stefan Timm, Stéphanie Arrivault, Alexandra Florian, Mark Stitt, Alisdair R Fernie, Hermann Bauwe. The Photorespiratory Metabolite 2-Phosphoglycolate Regulates Photosynthesis and Starch Accumulation in Arabidopsis. The Plant cell. 2017 Oct; 29(10):2537-2551. doi: 10.1105/tpc.17.00256. [PMID: 28947491]
  • Ken Nakahara, Hiroshi Yamamoto, Chikahiro Miyake, Akiho Yokota. Purification and characterization of class-I and class-II fructose-1,6-bisphosphate aldolases from the cyanobacterium Synechocystis sp. PCC 6803. Plant & cell physiology. 2003 Mar; 44(3):326-33. doi: 10.1093/pcp/pcg044. [PMID: 12668779]
  • Nicola T Wood. Cyanobacterial transgene paves the way to increased crop productivity. Trends in plant science. 2002 Jan; 7(1):9. doi: 10.1016/s1360-1385(01)02217-8. [PMID: 11804819]
  • Y Miyagawa, M Tamoi, S Shigeoka. Overexpression of a cyanobacterial fructose-1,6-/sedoheptulose-1,7-bisphosphatase in tobacco enhances photosynthesis and growth. Nature biotechnology. 2001 Oct; 19(10):965-9. doi: 10.1038/nbt1001-965. [PMID: 11581664]
  • R P Dunford, M A Catley, C A Raines, J C Lloyd, T A Dyer. Purification of active chloroplast sedoheptulose-1,7-bisphosphatase expressed in Escherichia coli. Protein expression and purification. 1998 Oct; 14(1):139-45. doi: 10.1006/prep.1998.0939. [PMID: 9758762]
  • N M Willingham, J C Lloyd, C A Raines. Molecular cloning of the Arabidopsis thaliana sedoheptulose-1,7-biphosphatase gene and expression studies in wheat and Arabidopsis thaliana. Plant molecular biology. 1994 Nov; 26(4):1191-200. doi: 10.1007/bf00040699. [PMID: 7811976]