Codeinone (BioDeep_00000004180)
natural product PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C18H19NO3 (297.1365)
中文名称: 可待因酮
谱图信息:
最多检出来源 Homo sapiens(otcml) 26.84%
分子结构信息
SMILES: CN1CCC23C4C1CC5=C2C(=C(C=C5)OC)OC3C(=O)C=C4
InChI: InChI=1S/C18H19NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3-6,11-12,17H,7-9H2,1-2H3/t11-,12+,17-,18-/m0/s1
描述信息
D002492 - Central Nervous System Depressants > D009294 - Narcotics > D053610 - Opiate Alkaloids
同义名列表
数据库引用编号
18 个数据库交叉引用编号
- ChEBI: CHEBI:18399
- KEGG: C06171
- PubChem: 5459910
- PubChem: 5149725
- Metlin: METLIN64385
- ChEMBL: CHEMBL257627
- MetaCyc: CODEINONE
- CAS: 467-13-0
- MoNA: PM000704
- PMhub: MS000015977
- MetaboLights: MTBLC18399
- PubChem: 8422
- KNApSAcK: C00027603
- 3DMET: B01979
- NIKKAJI: J11.325E
- RefMet: Codeinone
- LOTUS: LTS0095594
- KNApSAcK: 18399
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
11 个相关的物种来源信息
- 2759 - Eukaryota: LTS0095594
- 3398 - Magnoliopsida: LTS0095594
- 3468 - Papaver: LTS0095594
- 3469 - Papaver somniferum:
- 3469 - Papaver somniferum: 10.1016/0040-4039(95)00278-K
- 3469 - Papaver somniferum: 10.1016/S0040-4039(00)73838-X
- 3469 - Papaver somniferum: LTS0095594
- 3465 - Papaveraceae: LTS0095594
- 35493 - Streptophyta: LTS0095594
- 58023 - Tracheophyta: LTS0095594
- 33090 - Viridiplantae: LTS0095594
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Sanggil Choe, Eunjung Lee, Gang-nam Jin, Yang Han Lee, Soo Young Kim, Hwakyung Choi, Heesun Chung, Bang Yeon Hwang, Suncheun Kim. Genetic and chemical components analysis of Papaver setigerum naturalized in Korea.
Forensic science international.
2012 Oct; 222(1-3):387-93. doi:
10.1016/j.forsciint.2012.08.002. [PMID: 22921420] - Champa P Wijekoon, Peter J Facchini. Systematic knockdown of morphine pathway enzymes in opium poppy using virus-induced gene silencing.
The Plant journal : for cell and molecular biology.
2012 Mar; 69(6):1052-63. doi:
10.1111/j.1365-313x.2011.04855.x. [PMID: 22098111] - Md Sarfaraj Hussain, Sheeba Fareed, Saba Ansari, Md Akhlaquer Rahman, Iffat Zareen Ahmad, Mohd Saeed. Current approaches toward production of secondary plant metabolites.
Journal of pharmacy & bioallied sciences.
2012 Jan; 4(1):10-20. doi:
10.4103/0975-7406.92725. [PMID: 22368394] - Isabel Desgagné-Penix, Morgan F Khan, David C Schriemer, Dustin Cram, Jacek Nowak, Peter J Facchini. Integration of deep transcriptome and proteome analyses reveals the components of alkaloid metabolism in opium poppy cell cultures.
BMC plant biology.
2010 Nov; 10(?):252. doi:
10.1186/1471-2229-10-252. [PMID: 21083930] - Philip J Larkin, James A C Miller, Robert S Allen, Julie A Chitty, Wayne L Gerlach, Susanne Frick, Toni M Kutchan, Anthony J Fist. Increasing morphinan alkaloid production by over-expressing codeinone reductase in transgenic Papaver somniferum.
Plant biotechnology journal.
2007 Jan; 5(1):26-37. doi:
10.1111/j.1467-7652.2006.00212.x. [PMID: 17207254] - Jörg Ziegler, Susan Voigtländer, Jürgen Schmidt, Robert Kramell, Otto Miersch, Christian Ammer, Andreas Gesell, Toni M Kutchan. Comparative transcript and alkaloid profiling in Papaver species identifies a short chain dehydrogenase/reductase involved in morphine biosynthesis.
The Plant journal : for cell and molecular biology.
2006 Oct; 48(2):177-92. doi:
10.1111/j.1365-313x.2006.02860.x. [PMID: 16968522] - Nailish Samanani, Joenel Alcantara, Richard Bourgault, Katherine G Zulak, Peter J Facchini. The role of phloem sieve elements and laticifers in the biosynthesis and accumulation of alkaloids in opium poppy.
The Plant journal : for cell and molecular biology.
2006 Aug; 47(4):547-63. doi:
10.1111/j.1365-313x.2006.02801.x. [PMID: 16813579] - Joenel Alcantara, David A Bird, Vincent R Franceschi, Peter J Facchini. Sanguinarine biosynthesis is associated with the endoplasmic reticulum in cultured opium poppy cells after elicitor treatment.
Plant physiology.
2005 May; 138(1):173-83. doi:
10.1104/pp.105.059287. [PMID: 15849302] - Robert S Allen, Anthony G Millgate, Julie A Chitty, Jennifer Thisleton, James A C Miller, Anthony J Fist, Wayne L Gerlach, Philip J Larkin. RNAi-mediated replacement of morphine with the nonnarcotic alkaloid reticuline in opium poppy.
Nature biotechnology.
2004 Dec; 22(12):1559-66. doi:
10.1038/nbt1033. [PMID: 15543134] - David A Bird, Vincent R Franceschi, Peter J Facchini. A tale of three cell types: alkaloid biosynthesis is localized to sieve elements in opium poppy.
The Plant cell.
2003 Nov; 15(11):2626-35. doi:
10.1105/tpc.015396. [PMID: 14508000] - Peter J Facchini, Sang-Un Park. Developmental and inducible accumulation of gene transcripts involved in alkaloid biosynthesis in opium poppy.
Phytochemistry.
2003 Sep; 64(1):177-86. doi:
10.1016/s0031-9422(03)00292-9. [PMID: 12946416]
