Ethambutol (BioDeep_00000411070)

Main id: BioDeep_00000002168

 


代谢物信息卡片


Ethambutol

化学式: C10H24N2O2 (204.1837684)
中文名称: 乙胺丁醇
谱图信息: 最多检出来源 Homo sapiens(urine) 1.68%

分子结构信息

SMILES: CCC(CO)NCCNC(CC)CO
InChI: InChI=1S/C10H24N2O2/c1-3-9(7-13)11-5-6-12-10(4-2)8-14/h9-14H,3-8H2,1-2H3

描述信息

J - Antiinfectives for systemic use > J04 - Antimycobacterials > J04A - Drugs for treatment of tuberculosis
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D000995 - Antitubercular Agents
C254 - Anti-Infective Agent > C52588 - Antibacterial Agent > C280 - Antitubercular Agent
CONFIDENCE standard compound; INTERNAL_ID 4; HBM4EU - science and policy for a healthy future (https://www.hbm4eu.eu)
CONFIDENCE Reference Standard (Level 1); HBM4EU - science and policy for a healthy future (https://www.hbm4eu.eu); Flow Injection
CONFIDENCE Reference Standard (Level 1); HBM4EU - science and policy for a healthy future (https://www.hbm4eu.eu)
Flow Injection; CONFIDENCE Reference Standard (Level 1); HBM4EU - science and policy for a healthy future (https://www.hbm4eu.eu)

同义名列表

3 个代谢物同义名

Ethambutol; Ethambutol; Ethambutol



数据库引用编号

118 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Joana Gonçalves, Cláudia Marques, Cláudia Nunes, Mafalda Sarraguça. Therapeutic Liquid Eutectic Solvents in Lipid Nanoparticles as Drug Vehicles-A Proof of Concept. International journal of molecular sciences. 2023 Oct; 24(21):. doi: 10.3390/ijms242115648. [PMID: 37958633]
  • Wei-Yu Chen, Yi-Fang Chen, Jer-Min Tsai, Hsin-Mei Huang, Yong-Chao Su. Epidemiology-based wastewater monitoring for ecological risks of anti-tuberculosis drugs mixture effects. The Science of the total environment. 2023 Sep; 892(?):164560. doi: 10.1016/j.scitotenv.2023.164560. [PMID: 37268140]
  • Funmilayo Grâce Boni, Insaf Hamdi, Liadrine Moukendza Koundi, Yongdong Dai, Kanshan Shrestra, Mohamed Abdellah Abokadoum, Ulrich Aymard Ekomi Moure, Ismail Mohamed Suleiman, Jianping Xie. The Gene and Regulatory Network Involved in Ethambutol Resistance in Mycobacterium tuberculosis. Microbial drug resistance (Larchmont, N.Y.). 2023 May; 29(5):175-189. doi: 10.1089/mdr.2021.0239. [PMID: 35939307]
  • Yining Liu, Wenyan Chen, Yanli Cen, Xiaodeng Zhao, Zaiping Chen, Yuedong Liang, Zhongfeng Huang, Xiu He, Guanghong Yang. Hepatocyte ferroptosis contributes to anti-tuberculosis drug-induced liver injury: Involvement of the HIF-1α/SLC7A11/GPx4 axis. Chemico-biological interactions. 2023 Mar; ?(?):110439. doi: 10.1016/j.cbi.2023.110439. [PMID: 36878459]
  • Yuanqin Du, Jingjing Huang, Yaobin Nong, Ruixi Zhong, Ronghuo Zhu, Wenxuan Song, Hongna Huang, Qinwen Tan, Jian Xu, Xiyu Xiao, Juhong Jia. A case of ascetic fluid Mycobacterium aubagnense infection in a patient with severe peritoneal effusion. BMC infectious diseases. 2023 Feb; 23(1):84. doi: 10.1186/s12879-023-08041-1. [PMID: 36750816]
  • Mukaram Amatjan, Na Li, Pengke He, Boheng Zhang, Xianyan Mai, Qianle Jiang, Haochen Xie, Xiaoni Shao. A Novel Approach Based on Gut Microbiota Analysis and Network Pharmacology to Explain the Mechanisms of Action of Cichorium intybus L. Formula in the Improvement of Hyperuricemic Nephropathy in Rats. Drug design, development and therapy. 2023; 17(?):107-128. doi: 10.2147/dddt.s389811. [PMID: 36712944]
  • Na Chen, Hua Li, Jing Meng, Yi-Fei Yang, Bin Yang. [Anti-hyperuricemia activity and its mechanism of flavonoid extract from saffron floral bio-residues]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2023 Jan; 48(1):148-159. doi: 10.19540/j.cnki.cjcmm.20220928.401. [PMID: 36725267]
  • Jian Fu, Ziyao He, Huixiao Fu, Yufen Xia, Inès N'Go, Huayong Lou, Jinglan Wu, Weidong Pan, Stéphane P Vincent. Synthesis and evaluation of inhibitors of Mycobacterium tuberculosis UGM using bioisosteric replacement. Bioorganic & medicinal chemistry. 2022 09; 69(?):116896. doi: 10.1016/j.bmc.2022.116896. [PMID: 35777270]
  • Xiaocui Wu, Guangkun Tan, Jinghui Yang, Yinjuan Guo, Chengchen Huang, Wei Sha, Fangyou Yu. Prediction of Mycobacterium tuberculosis drug resistance by nucleotide MALDI-TOF-MS. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2022 Aug; 121(?):47-54. doi: 10.1016/j.ijid.2022.04.061. [PMID: 35523300]
  • Daniel Van Aartsen, Museveni Justine, Estomih Mduma, Stellah G Mpagama, Mohammad H Alshaer, Charles A Peloquin, Buliga Mujaga, Athanasia Maro, Jean Gratz, Margaret Kosek, Jie Liu, Elizabeth T Rogawski McQuade, Eric R Houpt, Tania A Thomas, Scott K Heysell. Enteropathogen spectrum and effect on antimycobacterial pharmacokinetics among children with tuberculosis in rural Tanzania: a prospective cohort study. The Lancet. Microbe. 2022 Jun; 3(6):e408-e416. doi: 10.1016/s2666-5247(21)00308-6. [PMID: 35659902]
  • Morris Muliaditan, Donato Teutonico, Fatima Ortega-Muro, Santiago Ferrer, Oscar Della Pasqua. Prediction of lung exposure to anti-tubercular drugs using plasma pharmacokinetic data: Implications for dose selection. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2022 Jun; 173(?):106163. doi: 10.1016/j.ejps.2022.106163. [PMID: 35248733]
  • Elisa Lopez-Varela, Ahmed A Abulfathi, Natasha Strydom, Pierre Goussard, Abraham C van Wyk, Anne Marie Demers, Anneen Van Deventer, Anthony J Garcia-Prats, Johannes van der Merwe, Matthew Zimmerman, Claire L Carter, Jacques Janson, Julie Morrison, Helmuth Reuter, Eric H Decloedt, James A Seddon, Elin M Svensson, Rob Warren, Radojka M Savic, Véronique Dartois, Anneke C Hesseling. Drug concentration at the site of disease in children with pulmonary tuberculosis. The Journal of antimicrobial chemotherapy. 2022 05; 77(6):1710-1719. doi: 10.1093/jac/dkac103. [PMID: 35468189]
  • Xiaocui Wu, Guangkun Tan, Wei Sha, Haican Liu, Jinghui Yang, Yinjuan Guo, Xin Shen, Zheyuan Wu, Hongbo Shen, Fangyou Yu. Use of Whole-Genome Sequencing to Predict Mycobacterium tuberculosis Complex Drug Resistance from Early Positive Liquid Cultures. Microbiology spectrum. 2022 04; 10(2):e0251621. doi: 10.1128/spectrum.02516-21. [PMID: 35311541]
  • Mike Marvin Ruth, Jelmer Raaijmakers, Erik van den Hombergh, Rob Aarnoutse, Elin M Svensson, Budi O Susanto, Ulrika S H Simonsson, Heiman Wertheim, Wouter Hoefsloot, Jakko van Ingen. Standard therapy of Mycobacterium avium complex pulmonary disease shows limited efficacy in an open source hollow fibre system that simulates human plasma and epithelial lining fluid pharmacokinetics. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 2022 Mar; 28(3):448.e1-448.e7. doi: 10.1016/j.cmi.2021.07.015. [PMID: 34332109]
  • Glauco Henrique Balthazar Nardotto, Valdes Roberto Bollela, Adriana Rocha, Oscar Della Pasqua, Vera Lucia Lanchote. No implication of HIV coinfection on the plasma exposure to rifampicin, pyrazinamide, and ethambutol in tuberculosis patients. Clinical and translational science. 2022 02; 15(2):514-523. doi: 10.1111/cts.13169. [PMID: 34670022]
  • Osamu Iketani, Akari Komeya, Yuki Enoki, Kazuaki Taguchi, Shunsuke Uno, Yoshifumi Uwamino, Kazuaki Matsumoto, Junko Kizu, Naoki Hasegawa. Impact of rifampicin on the pharmacokinetics of clarithromycin and 14-hydroxy clarithromycin in patients with multidrug combination therapy for pulmonary Mycobacterium avium complex infection. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2022 Jan; 28(1):61-66. doi: 10.1016/j.jiac.2021.10.003. [PMID: 34706852]
  • Agnija Kivrane, Solveiga Grinberga, Eduards Sevostjanovs, Viktorija Igumnova, Ilva Pole, Anda Viksna, Dace Bandere, Alvils Krams, Andra Cirule, Osvalds Pugovics, Renate Ranka. LC-MS/MS method for simultaneous quantification of the first-line anti-tuberculosis drugs and six primary metabolites in patient plasma: Implications for therapeutic drug monitoring. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2021 Nov; 1185(?):122986. doi: 10.1016/j.jchromb.2021.122986. [PMID: 34688197]
  • Andrew D McCallum, Henry E Pertinez, Laura J Else, Sujan Dilly-Penchala, Aaron P Chirambo, Irene Sheha, Madalitso Chasweka, Alex Chitani, Rose D Malamba, Jamilah Z Meghji, Stephen B Gordon, Geraint R Davies, Saye H Khoo, Derek J Sloan, Henry C Mwandumba. Intrapulmonary Pharmacokinetics of First-line Anti-tuberculosis Drugs in Malawian Patients With Tuberculosis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2021 11; 73(9):e3365-e3373. doi: 10.1093/cid/ciaa1265. [PMID: 32856694]
  • Teyim Pride Mbuh, Henry D Meriki, Benjamin D Thumamo Pokam, Wandji Adeline, Francaise Enoka, Tchualack Ghislain, Wilfred F Mbacham, Irene Ane-Anyangwe. Incidence of adverse drug events among patients on second line anti-tuberculosis regimen in the littoral region of cameroon. International journal of mycobacteriology. 2021 Oct; 10(4):463-468. doi: 10.4103/ijmy.ijmy_160_21. [PMID: 34916468]
  • R E Akhigbe, M A Hamed, A O Aremu. HAART exacerbates testicular damage and impaired spermatogenesis in anti-Koch-treated rats via dysregulation of lactate transport and glutathione content. Reproductive toxicology (Elmsford, N.Y.). 2021 08; 103(?):96-107. doi: 10.1016/j.reprotox.2021.06.007. [PMID: 34118364]
  • Gang Fang, Ning-Chang Cheng, Li-Li Huang, Wei-Ping Xie, Chun-Mei Hu, Wei Chen. The first report of co-existence of pulmonary tuberculosis and lung malignancy in a kidney transplant recipient: a case report and literature review. BMC infectious diseases. 2021 Jul; 21(1):629. doi: 10.1186/s12879-021-06350-x. [PMID: 34210287]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Wen-Yan Sheng, Ling-Ya Su, Wei Ge, Shuang-Qing Wu, Li-Wei Zhu. Analysis of structural injury patterns in peripapillary retinal nerve fibre layer and retinal ganglion cell layer in ethambutol-induced optic neuropathy. BMC ophthalmology. 2021 Mar; 21(1):132. doi: 10.1186/s12886-021-01881-y. [PMID: 33691649]
  • Y Tamzali, M Jamme, F Bottet, M Gauthe, E Rondeau, G Pialoux, R Calin. Intravesical BCG instillation as a possible cause of acute and chronic kidney injury. Infectious diseases now. 2021 Mar; 51(2):209-211. doi: 10.1016/j.medmal.2020.09.009. [PMID: 33007403]
  • Navarat Panjasawatwong, Thanaporn Wattanakul, Richard M Hoglund, Nguyen Duc Bang, Thomas Pouplin, Wichit Nosoongnoen, Vi Nguyen Ngo, Jeremy N Day, Joel Tarning. Population Pharmacokinetic Properties of Antituberculosis Drugs in Vietnamese Children with Tuberculous Meningitis. Antimicrobial agents and chemotherapy. 2020 12; 65(1):. doi: 10.1128/aac.00487-20. [PMID: 33139294]
  • Narjes Saheb Sharif-Askari, Fatemeh Saheb Sharif-Askari, Bushra Mdkhana, Saba Al Heialy, Elaref Ratemi, Malak Alghamdi, Salah Abusnana, Tarek Kashour, Qutayba Hamid, Rabih Halwani. Effect of common medications on the expression of SARS-CoV-2 entry receptors in liver tissue. Archives of toxicology. 2020 12; 94(12):4037-4041. doi: 10.1007/s00204-020-02869-1. [PMID: 32808185]
  • Xubin Zheng, Erwin M Jongedijk, Yi Hu, Johanna Kuhlin, Rongrong Zheng, Katarina Niward, Jakob Paues, Biao Xu, Lina Davies Forsman, Thomas Schön, Judith Bruchfeld, Jan-Willem C Alffenaar. Development and validation of a simple LC-MS/MS method for simultaneous determination of moxifloxacin, levofloxacin, prothionamide, pyrazinamide and ethambutol in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2020 Nov; 1158(?):122397. doi: 10.1016/j.jchromb.2020.122397. [PMID: 33091676]
  • Jun Wang, Jing Wang, Yadong Du, Ru Guo, Xiqin Han, Qingfeng Wang, Yu Pang, Naihui Chu. Effect of interval between food intake and drug administration at fasting condition on the plasma concentrations of first-line anti-tuberculosis drugs in Chinese population. Medicine. 2020 Oct; 99(44):e22258. doi: 10.1097/md.0000000000022258. [PMID: 33126298]
  • Le Kang, Jin-Xin Miao, Li-Hua Cao, Yan-Yan Miao, Ming-San Miao, Hui-Juan Liu, Li-Ling Xiang, Ya-Gang Song. Total glucosides of herbaceous peony (Paeonia lactiflora Pall.) flower attenuate adenine- and ethambutol-induced hyperuricaemia in rats. Journal of ethnopharmacology. 2020 Oct; 261(?):113054. doi: 10.1016/j.jep.2020.113054. [PMID: 32534113]
  • Sharad S Upadhyay, Nayan S Gadhari, Ashwini K Srivastava. Biomimetic sensor for ethambutol employing β-cyclodextrin mediated chiral copper metal organic framework and carbon nanofibers modified glassy carbon electrode. Biosensors & bioelectronics. 2020 Oct; 165(?):112397. doi: 10.1016/j.bios.2020.112397. [PMID: 32729518]
  • Bijoy Kumar Panda, Medha Bargaje, Sathiyanarayanan L. A simple and reliable analytical method for simultaneous quantification of first line antitubercular drugs in human plasma by LCMS/MS. Analytical methods : advancing methods and applications. 2020 08; 12(31):3909-3917. doi: 10.1039/d0ay00889c. [PMID: 32719834]
  • In Hee Lee, Seong Gyu Kim, Joong Goo Kwon, Chun-Seok Yang, Sungmin Kang, Min-Kyung Kim, Dong Jik Ahn. Intestinal tuberculosis in a patient with end-stage renal disease on hemodialysis: A case report. Medicine. 2020 Aug; 99(32):e21641. doi: 10.1097/md.0000000000021641. [PMID: 32769931]
  • Xiaocui Wu, Rongliang Gao, Xin Shen, Yinjuan Guo, Jinghui Yang, Zheyuan Wu, Guangkun Tan, Hongxiu Wang, Fangyou Yu. Use of whole-genome sequencing to predict Mycobacterium tuberculosis drug resistance in Shanghai, China. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2020 Jul; 96(?):48-53. doi: 10.1016/j.ijid.2020.04.039. [PMID: 32339720]
  • Letizia Carrara, Paolo Magni, Donato Teutonico, Lorenzo Pasotti, Oscar Della Pasqua, Frank Kloprogge. Ethambutol disposition in humans: Challenges and limitations of whole-body physiologically-based pharmacokinetic modelling in early drug development. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2020 Jul; 150(?):105359. doi: 10.1016/j.ejps.2020.105359. [PMID: 32361179]
  • Tsegahun Manyazewal, Yimtubezinash Woldeamanuel, David P Holland, Abebaw Fekadu, Henry M Blumberg, Vincent C Marconi. Electronic pillbox-enabled self-administered therapy versus standard directly observed therapy for tuberculosis medication adherence and treatment outcomes in Ethiopia (SELFTB): protocol for a multicenter randomized controlled trial. Trials. 2020 May; 21(1):383. doi: 10.1186/s13063-020-04324-z. [PMID: 32370774]
  • Mariana Millan Fachi, Raquel Oliveira Vilhena, Beatriz Boger, Eric Luiz Domingos, Josiane Marlei Müller Fernandes Dos Santos, Allan Michael Junkert, Alexandre de Fátima Cobre, Danilo Raul Ossufo Momade, Francisco Beraldi-Magalhães, Marcus Vinicius de Liz, Marcelo Cordeiro-Santos, Roberto Pontarolo. LC-QToF-MS method for quantification of ethambutol, isoniazid, pyrazinamide and rifampicin in human plasma and its application. Biomedical chromatography : BMC. 2020 May; 34(5):e4812. doi: 10.1002/bmc.4812. [PMID: 32068899]
  • Andreas H Diacon, Veronique R De Jager, Rodney Dawson, Kim Narunsky, Naadira Vanker, Divan A Burger, Daniel Everitt, Frances Pappas, Jerry Nedelman, Carl M Mendel. Fourteen-Day Bactericidal Activity, Safety, and Pharmacokinetics of Linezolid in Adults with Drug-Sensitive Pulmonary Tuberculosis. Antimicrobial agents and chemotherapy. 2020 03; 64(4):. doi: 10.1128/aac.02012-19. [PMID: 31988102]
  • Museveni Justine, Anita Yeconia, Ingi Nicodemu, Domitila Augustino, Jean Gratz, Estomih Mduma, Scott K Heysell, Sokoine Kivuyo, Sayoki Mfinanga, Charles A Peloquin, Theodore Zagurski, Gibson S Kibiki, Blandina Mmbaga, Eric R Houpt, Tania A Thomas. Pharmacokinetics of First-Line Drugs Among Children With Tuberculosis in Rural Tanzania. Journal of the Pediatric Infectious Diseases Society. 2020 Feb; 9(1):14-20. doi: 10.1093/jpids/piy106. [PMID: 30395239]
  • Lingjie Wu, Zhenjie Ye, Hui Liu, Hongliang Guo, Jing Lin, Ling Zheng, Nannan Chu, Xiaolong Liu. Rapid and highly sensitive quantification of the anti-tuberculosis agents isoniazid, ethambutol, pyrazinamide, rifampicin and rifabutin in human plasma by UPLC-MS/MS. Journal of pharmaceutical and biomedical analysis. 2020 Feb; 180(?):113076. doi: 10.1016/j.jpba.2019.113076. [PMID: 31896523]
  • Jesper Sundell, Emile Bienvenu, Sofia Birgersson, Angela Äbelö, Michael Ashton. Population Pharmacokinetics and Pharmacogenetics of Ethambutol in Adult Patients Coinfected with Tuberculosis and HIV. Antimicrobial agents and chemotherapy. 2020 01; 64(2):. doi: 10.1128/aac.01583-19. [PMID: 31712201]
  • Supavit Chesdachai, Prowpanga Udompap, Faqian Li, John R Lake, Mandip Kc. Pulmonary Mycobacterium Spindle Cell Pseudotumor in Patient With Liver Transplant. The American journal of the medical sciences. 2020 01; 359(1):42-50. doi: 10.1016/j.amjms.2019.10.016. [PMID: 31902440]
  • Arpitha Rao, Guruprasad Nayak, Sandhya Kumari, Sneha Guruprasad Kalthur, Sadhana P Mutalik, Srinivas Mutalik, Satish Kumar Adiga, Guruprasad Kalthur. Exposure to first line anti-tuberculosis drugs in prepubertal age reduces the quality and functional competence of spermatozoa and oocytes in Swiss albino mice. Environmental toxicology and pharmacology. 2020 Jan; 73(?):103292. doi: 10.1016/j.etap.2019.103292. [PMID: 31765964]
  • El Ghoul Jamel, Sghaier Ahmed. DRESS Syndrome and Chronic Renal Failure Induced by Ethambutol. The American journal of the medical sciences. 2019 11; 358(5):e19. doi: 10.1016/j.amjms.2019.06.003. [PMID: 31326092]
  • Qian Lei, Hao Wang, Yuan Zhao, Liyun Dang, Changsheng Zhu, Xiaohui Lv, Hui Wang, Jun Zhou. Determinants of serum concentration of first-line anti-tuberculosis drugs from China. Medicine. 2019 Oct; 98(41):e17523. doi: 10.1097/md.0000000000017523. [PMID: 31593125]
  • Krina Mehta, Shruthi Ravimohan, Jotam G Pasipanodya, Shashikant Srivastava, Chawangwa Modongo, Nicola M Zetola, Drew Weissman, Vijay Ivaturi, Tawanda Gumbo, Gregory P Bisson, Christopher Vinnard. Optimizing ethambutol dosing among HIV/tuberculosis co-infected patients: a population pharmacokinetic modelling and simulation study. The Journal of antimicrobial chemotherapy. 2019 10; 74(10):2994-3002. doi: 10.1093/jac/dkz265. [PMID: 31273386]
  • Yucel Karakurt, Halis Süleyman, Ferda Keskin Cimen, Gamze Tasli, Turgay Ucak, Erel Icel, Nezahat Kurt. The effects of lutein on optic nerve injury induced by ethambutol and isoniazid: an experimental study. Cutaneous and ocular toxicology. 2019 Jun; 38(2):136-140. doi: 10.1080/15569527.2018.1539010. [PMID: 30362367]
  • Vikas Kanaujia, Vaibhav K Jain, Kumudini Sharma, Rachna Agarwal, Prabhakar Mishra, Raj Kumar Sharma. Ethambutol-induced optic neuropathy in renal disorder: a clinico-electrophysiological study. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie. 2019 06; 54(3):301-305. doi: 10.1016/j.jcjo.2018.06.013. [PMID: 31109468]
  • Shengyuan Wu, Liai Lan, Jingjing Jiang, Xianting Ding, Chih-Ming Ho, Yuefen Lou, Guorong Fan. Simultaneous determination of the potent anti-tuberculosis regimen-Pyrazinamide, ethambutol, protionamide, clofazimine in beagle dog plasma using LC-MS/MS method coupled with 96-well format plate. Journal of pharmaceutical and biomedical analysis. 2019 May; 168(?):44-54. doi: 10.1016/j.jpba.2019.02.006. [PMID: 30784889]
  • Aparna Mukherjee, Rakesh Lodha, S K Kabra. Pharmacokinetics of First-Line Anti-Tubercular Drugs. Indian journal of pediatrics. 2019 05; 86(5):468-478. doi: 10.1007/s12098-019-02911-w. [PMID: 30915644]
  • Wei Zhang, Shichun Lun, Ling-Ling Liu, Shiqi Xiao, Guanfu Duan, Hendra Gunosewoyo, Fan Yang, Jie Tang, William R Bishai, Li-Fang Yu. Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis. Part II. Journal of medicinal chemistry. 2019 04; 62(7):3575-3589. doi: 10.1021/acs.jmedchem.9b00010. [PMID: 30875203]
  • Xianli Xu, Xiaojie Lao, Chunlan Zhang, Cunwei Cao, Huarong Ding, Yu Pang, Qiuyue Ning, Jun Zou, Ning Zang, Diefei Hu, Maowei Chen. Chronic Mycobacterium avium skin and soft tissue infection complicated with scalp osteomyelitis possibly secondary to anti-interferon-γ autoantibody formation. BMC infectious diseases. 2019 Feb; 19(1):203. doi: 10.1186/s12879-019-3771-3. [PMID: 30819109]
  • Elham Nemati, Ahad Mokhtarzadeh, Vahid Panahi-Azar, Ali Mohammadi, Hamed Hamishehkar, Mehran Mesgari-Abbasi, Jafar Ezzati Nazhad Dolatabadi, Miguel de la Guardia. Ethambutol-Loaded Solid Lipid Nanoparticles as Dry Powder Inhalable Formulation for Tuberculosis Therapy. AAPS PharmSciTech. 2019 Feb; 20(3):120. doi: 10.1208/s12249-019-1334-y. [PMID: 30796625]
  • Y Kamii, H Nagai, M Kawashima, M Matsuki, S Nagoshi, A Sato, S Kohno, M Ohgiya, K Ohta. Adverse reactions associated with long-term drug administration in Mycobacterium avium complex lung disease. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. 2018 12; 22(12):1505-1510. doi: 10.5588/ijtld.18.0171. [PMID: 30606324]
  • K M Obeid, M A Hassan, S Chinnakotla, J H Young. Genitourinary Tract Infection Due to Mycobacterium avium intracellulare Complex Infection in Pretransplant Setting With Recurrence Following Transplant: A Case Report. Transplantation proceedings. 2018 Dec; 50(10):3937-3939. doi: 10.1016/j.transproceed.2018.09.007. [PMID: 30577290]
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