L-Lactic acid (BioDeep_00000410633)
Main id: BioDeep_00000002143
PANOMIX_OTCML-2023 BioNovoGene_Lab2019 Volatile Flavor Compounds
代谢物信息卡片
化学式: C3H6O3 (90.0316926)
中文名称: L-乳酸, L-(+)-乳酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C(=O)O)O
InChI: InChI=1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m0/s1
描述信息
L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid.
L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid.
同义名列表
数据库引用编号
20 个数据库交叉引用编号
- ChEBI: CHEBI:422
- KEGG: C00186
- KEGGdrug: D71144
- PubChem: 107689
- DrugBank: DB14475
- ChEMBL: CHEMBL330546
- MeSH: Lactic Acid
- CAS: 79-33-4
- MoNA: HMDB0000190_ms_ms_1513
- MoNA: HMDB0000190_ms_ms_1514
- MoNA: HMDB0000190_ms_ms_1515
- ChEBI: CHEBI:16651
- PubChem: 3486
- KNApSAcK: C00001191
- PDB-CCD: 2OP
- 3DMET: B01180
- NIKKAJI: J9.134K
- medchemexpress: HY-Y0479
- BioNovoGene_Lab2019: BioNovoGene_Lab2019-55
- KNApSAcK: 16651
分类词条
相关代谢途径
Reactome(18)
- Metabolism
- Disease
- Transport of small molecules
- SLC-mediated transmembrane transport
- Transport of bile salts and organic acids, metal ions and amine compounds
- Signaling Pathways
- Organic cation/anion/zwitterion transport
- Organic anion transport
- Disorders of transmembrane transporters
- SLC transporter disorders
- Defective SLC22A12 causes renal hypouricemia 1 (RHUC1)
- The citric acid (TCA) cycle and respiratory electron transport
- Pyruvate metabolism and Citric Acid (TCA) cycle
- Signaling by GPCR
- GPCR ligand binding
- Class A/1 (Rhodopsin-like receptors)
- GPCR downstream signalling
- G alpha (i) signalling events
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
7 个相关的物种来源信息
- 3702 - Arabidopsis thaliana: 10.1073/PNAS.1403248111
- 4414 - Euryale ferox Salisb.: -
- 9606 - Homo sapiens: 10.1007/S11306-016-1051-4
- 8187 - Lates calcarifer: 10.3389/FPHYS.2020.00205
- 28511 - Pogostemon cablin: 10.1021/JF304466T
- 28901 - Salmonella enterica: 10.1039/C3MB25598K
- 652943 - Streptomyces lacticiproducens: 10.1099/IJS.0.019125-0
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Haifeng Li, Siyuan Chen, Mengyu Wang, Shuoshuo Shi, Wenjian Zhao, Guoyang Xiong, Jia Zhou, Jianhang Qu. Phosphate solubilization and plant growth properties are promoted by a lactic acid bacterium in calcareous soil.
Applied microbiology and biotechnology.
2024 Dec; 108(1):24. doi:
10.1007/s00253-023-12850-4
. [PMID: 38159115] - Mariannys Chavez, Sharon Viscardi, María José Ruiz, Eulàlia Sans-Serramitjana, Paola Durán. CLI: A new protocol for the isolation of Lactic Acid Bacteria from complex plant samples.
Journal of microbiological methods.
2024 Jun; 221(?):106937. doi:
10.1016/j.mimet.2024.106937
. [PMID: 38648958] - Zhenyuan Qian, Fang Wu, Guoqing Feng, Wenfa Lin, Xufan Cai, Jianzhang Wu, Kun Ke, Zaiyuan Ye, Guoxi Xu. A prognostic risk model based on lactate metabolism and transport-related lncRNAs for gastric adenocarcinoma.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.
2024 Jun; 29(4):211-221. doi:
10.1080/1354750x.2024.2341411
. [PMID: 38629165] - Anam Layla, Qamar Abbas Syed, Tahir Zahoor, Muhammad Shahid. Investigating the role of Lactiplantibacillus plantarum vs. spontaneous fermentation in improving nutritional and consumer safety of the fermented white cabbage sprouts.
International microbiology : the official journal of the Spanish Society for Microbiology.
2024 Jun; 27(3):753-764. doi:
10.1007/s10123-023-00426-1
. [PMID: 37700156] - Weijuan Zou, Feng Gao, Zheying Meng, Xiaojun Cai, Wu Chen, Yuanyi Zheng, Tao Ying, Longchen Wang, Jianrong Wu. Lactic acid responsive sequential production of hydrogen peroxide and consumption of glutathione for enhanced ferroptosis tumor therapy.
Journal of colloid and interface science.
2024 Jun; 663(?):787-800. doi:
10.1016/j.jcis.2024.03.001
. [PMID: 38442520] - Alexander S Shashkov, Natalia V Potekhina, Elena M Tul'skaya, Andrey S Dmitrenok, Sof'ya N Senchenkova, Vladimir I Torgov, Lubov V Dorofeeva, Lyudmila I Evtushenko. New lactate- and pyruvate-containing polysaccharide and rhamnomannan with xylose residues from the cell wall of Rathayibacter oskolensis VKM Ac-2121T.
Carbohydrate research.
2024 Jun; 540(?):109145. doi:
10.1016/j.carres.2024.109145
. [PMID: 38759341] - Isaac A Chávez-Guevara, Everardo González-Rodríguez, Verónica Moreno-Brito, Jorge A Pérez-León, Francisco J Amaro-Gahete, Marina Trejo-Trejo, Arnulfo Ramos-Jiménez. The polymorphism T1470A of the SLC16A1 gene is associated with the lactate and ventilatory thresholds but not with fat oxidation capacity in young men.
European journal of applied physiology.
2024 Jun; 124(6):1835-1843. doi:
10.1007/s00421-023-05407-w
. [PMID: 38216723] - Francesco Martelli, Valentina Bernini, Erasmo Neviani, Vitor Vasconcelos, Ralph Urbatzka. Lactic acid fermented microalgae and cyanobacteria as a new source of lipid reducing compounds: assessment through zebrafish Nile red fat metabolism assay and untargeted metabolomics.
Food & function.
2024 May; 15(10):5554-5565. doi:
10.1039/d4fo00699b
. [PMID: 38712867] - Yuanqing Gu, Björn M Reinhard. Membrane fluidity properties of lipid-coated polylactic acid nanoparticles.
Nanoscale.
2024 May; 16(17):8533-8545. doi:
10.1039/d3nr06464f
. [PMID: 38595322] - Nopparuj Soomherun, Narumol Kreua-Ongarjnukool, Saowapa Thumsing Niyomthai, Sorayouth Chumnanvej. Lipid-Polymer Hybrid Nanoparticles Synthesized via Lipid-Based Surface Engineering for a robust drug delivery platform.
Colloids and surfaces. B, Biointerfaces.
2024 May; 237(?):113858. doi:
10.1016/j.colsurfb.2024.113858
. [PMID: 38547797] - Fan Yan, Junchi Ma, Manjiang Peng, Congfang Xi, Sheng Chang, Ying Yang, Suohui Tian, Bo Zhou, Tao Liu. Lactic acid induced defense responses in tobacco against Phytophthora nicotianae.
Scientific reports.
2024 04; 14(1):9338. doi:
10.1038/s41598-024-60037-2
. [PMID: 38654120] - Jie Li, Yi Liu, Ru-Ting Li, Yan Liu, Feng Li. The Effect of Anti-fatigue Decoction on the Behaviors and Serological Indicators in a Central Fatigue Rat Model.
Journal of visualized experiments : JoVE.
2024 Apr; ?(206):. doi:
10.3791/66481
. [PMID: 38682926] - Xueyan Gu, Heng Wang, Lei Wang, Kang Zhang, Yuhu Tian, Xiaoya Wang, Guowei Xu, Zhiting Guo, Saad Ahmad, Hanyurwumutima Egide, Jiahui Liu, Jianxi Li, Huub F J Savelkoul, Jingyan Zhang, Xuezhi Wang. The antioxidant activity and metabolomic analysis of the supernatant of Streptococcus alactolyticus strain FGM.
Scientific reports.
2024 04; 14(1):8413. doi:
10.1038/s41598-024-58933-8
. [PMID: 38600137] - Wenbo Sun, Dan Xu, YanXing Yang, Linfei Wen, Hanjiang Yu, Yaowen Xing, Xiaopeng Song, Huan Li, Haibo Xu. Improved Detection of Target Metabolites in Brain Tumors with Intermediate TE, High SNR, and High Bandwidth Spin-Echo Sequence at 5T.
AJNR. American journal of neuroradiology.
2024 Apr; 45(4):461-467. doi:
10.3174/ajnr.a8150
. [PMID: 38453417] - Yueling Chen, Wenchao Yang, Zikang Hu, Xiaoyan Gao, Jingbiao Ye, Xiangqian Song, Baoshu Chen, Zhengqiu Li. Bionic structure and biocompatibilities of long chain branched poly(L-lactic acid) oriented microcellular foaming material.
International journal of biological macromolecules.
2024 Apr; 263(Pt 2):130467. doi:
10.1016/j.ijbiomac.2024.130467
. [PMID: 38423433] - Mette G B Pedersen, Nikolaj Rittig, Maj Bangshaab, Kristoffer Berg-Hansen, Nigopan Gopalasingam, Lars C Gormsen, Esben Søndergaard, Niels Møller. Effects of exogenous lactate on lipid, protein, and glucose metabolism-a randomized crossover trial in healthy males.
American journal of physiology. Endocrinology and metabolism.
2024 Apr; 326(4):E443-E453. doi:
10.1152/ajpendo.00301.2023
. [PMID: 38324259] - Yuying Chen, Qingwei He, Huangjie Lu, Jie Yang, Jiongming Han, Ying Zhu, Ping Hu. Visualization and correlation of drug release of risperidone/clozapine microspheres in vitro and in vivo based on FRET mechanism.
International journal of pharmaceutics.
2024 Mar; 653(?):123885. doi:
10.1016/j.ijpharm.2024.123885
. [PMID: 38325621] - Jiarong Song, Xue Dong, Yue Lan, Yunwei Lu, Xu Liu, Xuena Kang, Zhonglu Huang, Bisong Yue, Yu Liu, Wenjin Ma, Libo Zhang, Haijun Yan, Miao He, Zhenxin Fan, Tao Guo. Interpretation of vaginal metagenomic characteristics in different types of vaginitis.
mSystems.
2024 Mar; 9(3):e0137723. doi:
10.1128/msystems.01377-23
. [PMID: 38364107] - Elton T Montrazi, Keren Sasson, Lilach Agemy, Avigdor Scherz, Lucio Frydman. Molecular imaging of tumor metabolism: Insight from pyruvate- and glucose-based deuterium MRI studies.
Science advances.
2024 Mar; 10(11):eadm8600. doi:
10.1126/sciadv.adm8600
. [PMID: 38478615] - Peiyan Yang, Hui Li, Mingjun Sun, Xinxin Guo, Yinghao Liao, Mohan Hu, Ping Ye, Ran Liu. Zinc deficiency drives ferroptosis resistance by lactate production in esophageal squamous cell carcinoma.
Free radical biology & medicine.
2024 03; 213(?):512-522. doi:
10.1016/j.freeradbiomed.2024.01.041
. [PMID: 38301975] - Jiaojiao Liao, Chenyuan Qin, Zongyu Wang, Ling Gao, Shimo Zhang, Yuting Feng, Jue Liu, Liyuan Tao. Effect of shenfu injection in patients with septic shock: A systemic review and meta-analysis for randomized clinical trials.
Journal of ethnopharmacology.
2024 Feb; 320(?):117431. doi:
10.1016/j.jep.2023.117431
. [PMID: 37981120] - Wenhui Duan, Lingxi Zhou, Yilin Ren, Fei Liu, Yuzheng Xue, Fang-Zhou Wang, Ran Lu, Xiao-Juan Zhang, Jin-Song Shi, Zheng-Hong Xu, Yan Geng. Lactic acid fermentation of goji berries (Lycium barbarum) prevents acute alcohol liver injury and modulates gut microbiota and metabolites in mice.
Food & function.
2024 Feb; 15(3):1612-1626. doi:
10.1039/d3fo03324d
. [PMID: 38240339] - Wei Bo, Ning Yu, Xiaokai Wang, Chun Wang, Chunying Liu. Lactate promoted cisplatin resistance in NSCLC by modulating the m6A modification-mediated FOXO3/MAGI1-IT1/miR-664b-3p/IL-6R axis.
Neoplasia (New York, N.Y.).
2024 Feb; 48(?):100960. doi:
10.1016/j.neo.2023.100960
. [PMID: 38184887] - Natalia Hernández-Herreros, Virginia Rivero-Buceta, Isabel Pardo, M Auxiliadora Prieto. Production of poly(3-hydroxybutyrate)/poly(lactic acid) from industrial wastewater by wild-type Cupriavidus necator H16.
Water research.
2024 Feb; 249(?):120892. doi:
10.1016/j.watres.2023.120892
. [PMID: 38007895] - Sydney Stanley, Xin Wang, Qingyun Liu, Young Yon Kwon, Abigail M Frey, Nathan D Hicks, Andrew J Vickers, Sheng Hui, Sarah M Fortune. Ongoing evolution of the Mycobacterium tuberculosis lactate dehydrogenase reveals the pleiotropic effects of bacterial adaption to host pressure.
PLoS pathogens.
2024 Feb; 20(2):e1012050. doi:
10.1371/journal.ppat.1012050
. [PMID: 38422159] - Yihan Ni, Xiangdeng Lai, Lin Li, Jingquan Sun, Yaqian Qu, Siyu Chen, Hao Zhang. Role of GPR81 in regulating intramuscular triglyceride storage during aerobic exercise in rats.
Physiology international.
2024 Jan; ?(?):. doi:
10.1556/2060.2023.00238
. [PMID: 38294536] - Yanhui Zhao, Min Zhao, Yumeng Zhang, Zixuan Fu, Tong Jin, Jiaxi Song, Yihe Huang, Chunjie Zhao, Miao Wang. Bile acids metabolism involved in the beneficial effects of Danggui Shaoyao San via gut microbiota in the treatment of CCl4 induced hepatic fibrosis.
Journal of ethnopharmacology.
2024 Jan; 319(Pt 3):117383. doi:
10.1016/j.jep.2023.117383
. [PMID: 37925004] - Jing Yang, Glenn R Gourley, Adam Gilbertsen, Chi Chen, Lei Wang, Karen Smith, Marion Namenwirth, Libang Yang. High Glucose Levels Promote Switch to Synthetic Vascular Smooth Muscle Cells via Lactate/GPR81.
Cells.
2024 Jan; 13(3):. doi:
10.3390/cells13030236
. [PMID: 38334628] - Gorka Prieto-Bellver, Javier Diaz-Lara, David J Bishop, José Fernández-Sáez, Javier Abián-Vicén, Iñigo San-Millan, Jordan Santos-Concejero. A Five-Week Periodized Carbohydrate Diet Does Not Improve Maximal Lactate Steady-State Exercise Capacity and Substrate Oxidation in Well-Trained Cyclists compared to a High-Carbohydrate Diet.
Nutrients.
2024 Jan; 16(2):. doi:
10.3390/nu16020318
. [PMID: 38276556] - Yongzhan Zhu, Yinghao Li, Xiaosong Zhou, Haoxuan Li, Min Guo, Peibiao Zhang. Glucose microenvironment sensitive degradation of arginine modified calcium sulfate reinforced poly(lactide-co-glycolide) composite scaffolds.
Journal of materials chemistry. B.
2024 Jan; 12(2):508-524. doi:
10.1039/d3tb01595e
. [PMID: 38108579] - Fei Tang, Dong Liu, Feng Wan, Li Zhang, Li-Yue Xu, Jing-Nan Zhang, Xiao-Lan Zhao, Hui Ao, Cheng Peng. Ameliorative effect of anisodamine (654-1/654-2) against myocardial dysfunction induced by septic shock via the NF-κB/NLRP-3 or the PI3K-AKT/NF-κB pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Jan; 123(?):155277. doi:
10.1016/j.phymed.2023.155277
. [PMID: 38128396] - Tine Van den Bossche, Karen Goossens, Geert Haesaert, Eva Wambacq, Leen Vandaele, Johan L De Boever. Autumn grass treated with a hydrolysable tannin extract versus lactic acid bacteria inoculant: Effects on silage fermentation characteristics and nutritional value and on performance of lactating dairy cows.
Journal of animal physiology and animal nutrition.
2024 Jan; 108(1):111-125. doi:
10.1111/jpn.13871
. [PMID: 37602531] - Devendra Paudel, Divek V T Nair, Sangshan Tian, Fuhua Hao, Umesh K Goand, Grace Joseph, Eleni Prodes, Zhi Chai, Chloé E M Robert, Benoit Chassaing, Andrew D Patterson, Vishal Singh. Dietary fiber guar gum-induced shift in gut microbiota metabolism and intestinal immune activity enhances susceptibility to colonic inflammation.
Gut microbes.
2024 Jan; 16(1):2341457. doi:
10.1080/19490976.2024.2341457
. [PMID: 38630030] - Cui Wang, Xiaoting Wang, Hongmin Zhang, Dawei Liu, Chengyuan Zhang. Effect of Norepinephrine on Peripheral Perfusion Index and Its Association With the Prognosis of Patients With Sepsis.
Journal of intensive care medicine.
2024 Jan; 39(1):21-27. doi:
10.1177/08850666231187333
. [PMID: 37431214] - Wei Zhou Teo, Jie Yang See, Sheena Ramazanu, James Chun Yip Chan, Xi Vivien Wu. Effect of lactic acid fermented foods on glycemic control in diabetic adults: a systemic review and meta-analysis of randomized controlled trials.
Critical reviews in food science and nutrition.
2024; 64(10):2863-2878. doi:
10.1080/10408398.2022.2128032
. [PMID: 36178255] - Lang Bai, Qibin Han, Zeyu Han, Xiaoyu Zhang, Jingwen Zhao, Huitong Ruan, Junliang Wang, Feng Lin, Wenguo Cui, Xing Yang, Yuefeng Hao. Stem Cells Expansion Vector via Bioadhesive Porous Microspheres for Accelerating Articular Cartilage Regeneration.
Advanced healthcare materials.
2024 Jan; 13(3):e2302327. doi:
10.1002/adhm.202302327
. [PMID: 37947298] - Yirivinti Hayagreeva Dinakar, Naveen Rajana, Nalla Usha Kumari, Vikas Jain, Neelesh Kumar Mehra. Recent Advances of Multifunctional PLGA Nanocarriers in the Management of Triple-Negative Breast Cancer.
AAPS PharmSciTech.
2023 Dec; 24(8):258. doi:
10.1208/s12249-023-02712-7
. [PMID: 38097825] - Jing Wu, Panchaonan Huang, Yunzi Feng, Chun Cui, Jucai Xu, Laihao Li. Enhancing Kokumi Sensation and Reducing Bitterness in Acid-Hydrolyzed Vegetable Proteins through Lactate and Thermal Processing.
Journal of agricultural and food chemistry.
2023 Dec; 71(49):19694-19704. doi:
10.1021/acs.jafc.3c04282
. [PMID: 38016698] - Roland Eghoghosoa Akhigbe, Bayo-Olugbami Adedamola Aminat, Tunmise Maryanne Akhigbe, Moses Agbomhere Hamed. Glutamine Alleviates I/R-Induced Intestinal Injury and Dysmotility Via the Downregulation of Xanthine Oxidase/Uric Acid Signaling and Lactate Generation in Wistar Rats.
The Journal of surgical research.
2023 Dec; 295(?):431-441. doi:
10.1016/j.jss.2023.11.041
. [PMID: 38070257] - Chen Chen, Zihang Shi, Xiankang Fan, Lihui Du, Changyu Zhou, Daodong Pan. Combined application of high-throughput sequencing and LC-MS-based lipidomics in the evaluation of microorganisms and lipidomics of restructured ham of different salted substitution.
Food research international (Ottawa, Ont.).
2023 12; 174(Pt 1):113596. doi:
10.1016/j.foodres.2023.113596
. [PMID: 37986459] - Yansheng Zhao, Mei Xiao, Aya Samy Eweys, Juan Bai, Osama M Darwesh, Xiang Xiao. Cinnamaldehyde Alleviates the Oxidative Stress of Caenorhabditis elegans in the Presence of Lactic Acid.
Plant foods for human nutrition (Dordrecht, Netherlands).
2023 Dec; 78(4):683-690. doi:
10.1007/s11130-023-01094-2
. [PMID: 37688685] - Gulay Ozkan. Valorization of artichoke outer petals by using ultrasound-assisted extraction and natural deep eutectic solvents (NADES) for the recovery of phenolic compounds.
Journal of the science of food and agriculture.
2023 Nov; ?(?):. doi:
10.1002/jsfa.13158
. [PMID: 37989526] - Bin Guo, Hui Shu, Ling Luo, Xiangpeng Liu, Yue Ma, Jie Zhang, Zhiwei Liu, Yong Zhang, Lei Fu, Tongxing Song, Yixue Qiao, Chi Zhang. Lactate Conversion by Lactate Dehydrogenase B Is Involved in Beige Adipocyte Differentiation and Thermogenesis in Mice.
Nutrients.
2023 Nov; 15(22):. doi:
10.3390/nu15224846
. [PMID: 38004240] - Elton T Montrazi, Keren Sasson, Lilach Agemy, Dana C Peters, Ori Brenner, Avigdor Scherz, Lucio Frydman. High-sensitivity deuterium metabolic MRI differentiates acute pancreatitis from pancreatic cancers in murine models.
Scientific reports.
2023 11; 13(1):19998. doi:
10.1038/s41598-023-47301-7
. [PMID: 37968574] - Samantha L Moss, Edward Brindley, Kevin Enright, Jamie Highton, Richard Bott. The Effects of an Acute Dose of New Zealand Blackcurrant Extract on 5-km Running Performance.
International journal of sport nutrition and exercise metabolism.
2023 Nov; 33(6):323-330. doi:
10.1123/ijsnem.2023-0029
. [PMID: 37648248] - Li-Li Huang, Zi Qing Chua, Krzysztof Buchowiecki, Chamarthi Maheswar Raju, Pawel L Urban. Hydrogel-enzyme micropatch array format for chemical mapping: A proof of concept.
Biosensors & bioelectronics.
2023 Nov; 239(?):115599. doi:
10.1016/j.bios.2023.115599
. [PMID: 37611447] - Jiawen Duan, Chenhui Li, Yimeng Zheng, Aiyou Huang, Zhenyu Xie. Characterization of exogenous lactate addition on the growth, photosynthetic performance, and biochemical composition of four bait microalgae strains.
Journal of applied microbiology.
2023 Nov; 134(11):. doi:
10.1093/jambio/lxad259
. [PMID: 37960882] - Qinjuan Wu, Xin Li, Menghong Long, Xianfeng Xie, Qing Liu. Integrated analysis of histone lysine lactylation (Kla)-specific genes suggests that NR6A1, OSBP2 and UNC119B are novel therapeutic targets for hepatocellular carcinoma.
Scientific reports.
2023 10; 13(1):18642. doi:
10.1038/s41598-023-46057-4
. [PMID: 37903971] - Ruiyuan Jiang, Shujuan Luo, Meng Zhang, Wei Wang, Shaoyuan Zhuo, Yajing Wu, Qingmei Qiu, Yuan Yuan, Xiao Jiang. Ginsenoside Rh4 inhibits inflammation-related hepatocellular carcinoma progression by targeting HDAC4/IL-6/STAT3 signaling.
Molecular genetics and genomics : MGG.
2023 Oct; ?(?):. doi:
10.1007/s00438-023-02070-w
. [PMID: 37843550] - Xuefei Chen, Wenhua Huang, Jingbo Zhang, Yanjun Li, Zheng Xing, Lanlan Guo, Hongfeng Jiang, Jing Zhang. High-intensity interval training induces lactylation of fatty acid synthase to inhibit lipid synthesis.
BMC biology.
2023 09; 21(1):196. doi:
10.1186/s12915-023-01698-9
. [PMID: 37726733] - Ulf Kulik, Caroline Moesta, Reinhard Spanel, Jürgen Borlak. Dysfunctional Cori and Krebs cycle and inhibition of lactate transporters constitute a mechanism of primary non-function of fatty liver allografts.
Translational research : the journal of laboratory and clinical medicine.
2023 Sep; ?(?):. doi:
10.1016/j.trsl.2023.09.006
. [PMID: 37722450] - Ma Yingjun, Tang Shuo, Jiang Liuyun, Zhang Yan, Su Shengpei. Study on a co-hybrid nano-hydroxyapatite with lignin derivatives and alendronate and the reinforce effect for poly(lactide-co-glycolide).
International journal of biological macromolecules.
2023 Sep; 253(Pt 2):126785. doi:
10.1016/j.ijbiomac.2023.126785
. [PMID: 37696379] - Lele Jian, Xing Gao, Chao Wang, Xiao Sun, Yuqiao Xu, Ruili Han, Yuying Wang, Shenhui Xu, Lan Ding, Jingjun Zhou, Yu Gu, Yuanlin Zhao, Ying Yang, Yuan Yuan, Jing Ye, Lijun Zhang. Perilipin 5 deficiency aggravates cardiac hypertrophy by stimulating lactate production in leptin-deficient mice.
Biology direct.
2023 Sep; 18(1):54. doi:
10.1186/s13062-023-00411-8
. [PMID: 37667357] - Mingzhu Yu, Qiaoling Pan, Wenbiao Li, Tingting Du, Fei Huang, Hui Wu, Yixin He, Xiaojun Wu, Hailian Shi. Isoliquiritigenin inhibits gastric cancer growth through suppressing GLUT4 mediated glucose uptake and inducing PDHK1/PGC-1α mediated energy metabolic collapse.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2023 Sep; 121(?):155045. doi:
10.1016/j.phymed.2023.155045
. [PMID: 37742526] - Isaac A Chávez-Guevara, Rosa P Hernández-Torres, Marina Trejo-Trejo, Verónica Moreno-Brito, Everardo González-Rodríguez, Arnulfo Ramos-Jiménez. Association Among Different Aerobic Threshold Markers and FATmax in Men With Obesity.
Research quarterly for exercise and sport.
2023 09; 94(3):861-868. doi:
10.1080/02701367.2022.2065235
. [PMID: 35512235] - Hanife Yuksel Cakmak, Hasan Ege, Senanur Yilmaz, Gokhan Agturk, Fulya Dal Yontem, Gozde Enguven, Abdurrahman Sarmis, Zeren Cakmak, Oguzhan Gunduz, Zeynep Ruya Ege. 3D printed Styrax Liquidus (Liquidambar orientalis Miller)-loaded poly (L-lactic acid)/chitosan based wound dressing material: Fabrication, characterization, and biocompatibility results.
International journal of biological macromolecules.
2023 Sep; 248(?):125835. doi:
10.1016/j.ijbiomac.2023.125835
. [PMID: 37473890] - Marcin Feldo, Magdalena Wójciak, Sławomir Dresler, Paweł Sowa, Bartosz J Płachno, Dariusz Samborski, Ireneusz Sowa. Effect of Diosmin on Selected Parameters of Oxygen Homeostasis.
International journal of molecular sciences.
2023 Aug; 24(16):. doi:
10.3390/ijms241612917
. [PMID: 37629098] - V Radhalakshmi, Maya Raman, Minnu Rose Joy. Development of active packaging film based on poly (lactic acid) incorporated with Piper betel leaf ethanolic extract and its application in the shelf-life extension of tuna meat.
International journal of biological macromolecules.
2023 Aug; 246(?):125751. doi:
10.1016/j.ijbiomac.2023.125751
. [PMID: 37429339] - Zhihang Liao, Shanshan Chen, Lanlan Zhang, Sujie Li, Yan Zhang, Xunan Yang. Microbial assemblages in water hyacinth silages with different initial moistures.
Environmental research.
2023 08; 231(Pt 2):116199. doi:
10.1016/j.envres.2023.116199
. [PMID: 37211182] - Weixia Sun, Mengshu Jia, Yingyan Feng, Xiawei Cheng. Lactate is a bridge linking glycolysis and autophagy through lactylation.
Autophagy.
2023 Aug; ?(?):. doi:
10.1080/15548627.2023.2246356
. [PMID: 37565742] - Wenbin Xiao, Kerui He, Chong Yu, Zeming Zhou, Liye Xia, Shibao Xie, Hanqi Li, Ming Zhang, Zhifeng Zhang, Pei Luo, Lu Wen, Gang Chen. Space Station-like Composite Nanoparticles for Co-Delivery of Multiple Natural Compounds from Chinese Medicine and Hydrogen in Combating Sensorineural Hearing Loss.
Molecular pharmaceutics.
2023 08; 20(8):3987-4006. doi:
10.1021/acs.molpharmaceut.3c00177
. [PMID: 37503854] - Dylan G Chitwood, Lisa Uy, Wanfang Fu, Stephanie R Klaubert, Sarah W Harcum, Christopher A Saski. Dynamics of Amino Acid Metabolism, Gene Expression, and Circulomics in a Recombinant Chinese Hamster Ovary Cell Line Adapted to Moderate and High Levels of Extracellular Lactate.
Genes.
2023 08; 14(8):. doi:
10.3390/genes14081576
. [PMID: 37628627] - Zi Shi, Miaoyi Zhou, Wei Song, Ya Liu, Ronghuan Wang, Yuandong Wang, Ruyang Zhang, Jiuran Zhao, Wen Ren. Trash to treasure: lactate and protein lactylation in maize root impacts response to drought.
Science China. Life sciences.
2023 08; 66(8):1903-1914. doi:
10.1007/s11427-023-2361-1
. [PMID: 37273069] - Julia Brenmoehl, Elli Brosig, Nares Trakooljul, Christina Walz, Daniela Ohde, Antonia Noce, Michael Walz, Martina Langhammer, Stefan Petkov, Monika Röntgen, Steffen Maak, Christina E Galuska, Beate Fuchs, Björn Kuhla, Siriluck Ponsuksili, Klaus Wimmers, Andreas Hoeflich. Metabolic Pathway Modeling in Muscle of Male Marathon Mice (DUhTP) and Controls (DUC)-A Possible Role of Lactate Dehydrogenase in Metabolic Flexibility.
Cells.
2023 07; 12(15):. doi:
10.3390/cells12151925
. [PMID: 37566003] - Sheng An, Yi Yao, Hongbin Hu, Junjie Wu, Jiaxin Li, Lulan Li, Jie Wu, Maomao Sun, Zhiya Deng, Yaoyuan Zhang, Shenhai Gong, Qiaobing Huang, Zhongqing Chen, Zhenhua Zeng. PDHA1 hyperacetylation-mediated lactate overproduction promotes sepsis-induced acute kidney injury via Fis1 lactylation.
Cell death & disease.
2023 07; 14(7):457. doi:
10.1038/s41419-023-05952-4
. [PMID: 37479690] - Shulan Han, Xueying Bao, Yifang Zou, Lingzhi Wang, Yutong Li, Leilei Yang, Anqi Liao, Xuemei Zhang, Xin Jiang, Di Liang, Yun Dai, Qing-Chuan Zheng, Zhuo Yu, Jianfeng Guo. d-lactate modulates M2 tumor-associated macrophages and remodels immunosuppressive tumor microenvironment for hepatocellular carcinoma.
Science advances.
2023 07; 9(29):eadg2697. doi:
10.1126/sciadv.adg2697
. [PMID: 37467325] - Tiantian Liu, Zhenliang Wen, Lujing Shao, Yun Cui, Xiaomeng Tang, Huijie Miao, Jingyi Shi, Linlin Jiang, Shuyun Feng, Yilin Zhao, Hong Zhang, Qiming Liang, Dechang Chen, Yucai Zhang, Chunxia Wang. ATF4 knockdown in macrophage impairs glycolysis and mediates immune tolerance by targeting HK2 and HIF-1α ubiquitination in sepsis.
Clinical immunology (Orlando, Fla.).
2023 Jul; 254(?):109698. doi:
10.1016/j.clim.2023.109698
. [PMID: 37481013] - F A Piran Filho, J M Bragatto, C S Parra, S M S Silva, P J Roco, L F Ferraretto, M N Pereira, J L P Daniel. Physical effectiveness of corn silage fractions stratified with the Penn State Particle Separator for lactating dairy cows.
Journal of dairy science.
2023 Jul; ?(?):. doi:
10.3168/jds.2022-23063
. [PMID: 37474365] - Jyoti Singh, Abha Sharma, Pushpendra Sharma, Govind Singh Tomar, Minakshi Grover, Surender Singh, Lata Nain. Production of ethanol, lipid and lactic acid from mixed agrowastes hydrolysate.
Natural product research.
2023 Jul; 37(15):2575-2582. doi:
10.1080/14786419.2022.2061480
. [PMID: 35382651] - Ziyu Zhu, Xiaoqian Chen, Wenhao Li, Yingping Zhuang, Yuzheng Zhao, Guan Wang. Understanding the effect of temperature downshift on CHO cell growth, antibody titer and product quality by intracellular metabolite profiling and in vivo monitoring of redox state.
Biotechnology progress.
2023 Jul; 39(4):e3352. doi:
10.1002/btpr.3352
. [PMID: 37141532] - Li-Li Wang, Yu-Mo Tian, Sen Hu, Hai-Pai Zhang, Xiang-Xi Meng, Hui-Ping Zhang, Yu-Xian Zhong, Ming-Hua Du, Yu Ding. Study on an Animal Model of Seawater Immersion Injury Following Hemorrhagic Shock.
The Journal of surgical research.
2023 07; 287(?):24-32. doi:
10.1016/j.jss.2023.01.012
. [PMID: 36863270] - Eleftheria Papadopoulou, Charlene Vance, Paloma S Rozene Vallespin, Panagiotis Tsapekos, Irini Angelidaki. Saccharina latissima, candy-factory waste, and digestate from full-scale biogas plant as alternative carbohydrate and nutrient sources for lactic acid production.
Bioresource technology.
2023 Jul; 380(?):129078. doi:
10.1016/j.biortech.2023.129078
. [PMID: 37100293] - Sukanya Phuengjayaem, Saranporn Poothong, Jaruwan Sitdhipol, Neungnut Chaiyawan, Sitanan Thitiprasert, Nuttha Thongchul, Somboon Tanasupawat. Sporolactobacillus mangiferae sp. nov., a spore-forming lactic acid bacterium isolated from tree bark in Thailand.
International journal of systematic and evolutionary microbiology.
2023 Jul; 73(7):. doi:
10.1099/ijsem.0.005993
. [PMID: 37493028] - Sara S Marques, David J H Cant, Caterina Minelli, Marcela A Segundo. Combining orthogonal measurements to unveil diclofenac encapsulation into polymeric and lipid nanocarriers.
Analytica chimica acta.
2023 Jun; 1262(?):341234. doi:
10.1016/j.aca.2023.341234
. [PMID: 37179055] - Austin Campbell, Kristi Gdanetz, Alexander W Schmidt, Thomas M Schmidt. H2 generated by fermentation in the human gut microbiome influences metabolism and competitive fitness of gut butyrate producers.
Microbiome.
2023 Jun; 11(1):133. doi:
10.1186/s40168-023-01565-3
. [PMID: 37322527] - Jie Zhao, Hao-Peng Liu, Xue-Jing Yin, Zhi-Hao Dong, Si-Ran Wang, Jun-Feng Li, Tao Shao. Dynamics of Phyllosphere Microbiota and Chemical Parameters at Various Growth Stages and Their Contribution to Anaerobic Fermentation of Pennisetum giganteum.
Microbiology spectrum.
2023 06; 11(3):e0228822. doi:
10.1128/spectrum.02288-22
. [PMID: 37010418] - Yuanyuan Li, Chaojie Wang, Xile Deng, Runze Cai, Lidong Cao, Chong Cao, Li Zheng, Pengyue Zhao, Qiliang Huang. Preparation of Thifluzamide Polylactic Acid Glycolic Acid Copolymer Microspheres and Its Effect on the Growth of Cucumber Seedlings.
International journal of molecular sciences.
2023 Jun; 24(12):. doi:
10.3390/ijms241210121
. [PMID: 37373269] - Asghar Narmani, Roghayyeh Jahedi, Ehsan Bakhshian-Dehkordi, Saeid Ganji, Mahnaz Nemati, Ruhollah Ghahramani-Asl, Kave Moloudi, Seyed Mohammad Hosseini, Hamed Bagheri, Prashant Kesharwani, Ali Khani, Bagher Farhood, Amirhossein Sahebkar. Biomedical applications of PLGA nanoparticles in nanomedicine: Advances in drug delivery systems and cancer therapy.
Expert opinion on drug delivery.
2023 Jun; ?(?):. doi:
10.1080/17425247.2023.2223941
. [PMID: 37294853] - Patryk Zdziobek, Grzegorz Stefan Jodłowski, Edyta Aneta Strzelec. Biopreservation and Bioactivation Juice from Waste Broccoli with Lactiplantibacillus plantarum.
Molecules (Basel, Switzerland).
2023 Jun; 28(12):. doi:
10.3390/molecules28124594
. [PMID: 37375149] - Da-Young Jee, Jae-Won Ha. Inactivation of Escherichia coli O157:H7, Salmonella Typhimurium, and Listeria monocytogenes on stainless steel by synergistic effects of tap water-based neutral electrolyzed water and lactic acid.
Food microbiology.
2023 Jun; 112(?):104233. doi:
10.1016/j.fm.2023.104233
. [PMID: 36906304] - Raffaella Capasso, Alberto Negro, Camilla Russo, Fabio Zeccolini, Gianluca Muto, Ferdinando Caranci, Antonio Pinto. Conventional and Advanced MRI Techniques in the Evaluation of Primary CNS Lymphoma.
Seminars in ultrasound, CT, and MR.
2023 Jun; 44(3):126-135. doi:
10.1053/j.sult.2023.02.003
. [PMID: 37245879] - Josly Pierre-Louis Odoom, Margaret A T Freeberg, Sarah V Camus, Robin Toft, Barbara B Szomju, Rose Marie Sanchez Rosado, Peter D Jackson, Jeremy C Allegood, Scott Silvey, Jinze Liu, L Ashley Cowart, Elisabeth Weiss, Thomas H Thatcher, Patricia J Sime. Exhaled breath condensate identifies metabolic dysregulation in patients with radiation-induced lung injury.
American journal of physiology. Lung cellular and molecular physiology.
2023 06; 324(6):L863-L869. doi:
10.1152/ajplung.00439.2022
. [PMID: 37039378] - Ellen McMullen, Helen Hertenstein, Katrin Strassburger, Leon Deharde, Marko Brankatschk, Stefanie Schirmeier. Glycolytically impaired Drosophila glial cells fuel neural metabolism via β-oxidation.
Nature communications.
2023 05; 14(1):2996. doi:
10.1038/s41467-023-38813-x
. [PMID: 37225684] - A Gorga, G M Rindone, M E Dasso, C L Centola, E H Pellizzari, M C Camberos, J Toneatto, M F Riera, M N Galardo, S B Meroni. Simultaneous regulation of lactate production and fatty acid metabolism by Resveratrol in rat Sertoli cells.
Biochimie.
2023 May; 208(?):75-85. doi:
10.1016/j.biochi.2022.12.006
. [PMID: 36528184] - Hongwu Li, Jingyi Chen, Xinyue Xing, Danfei Lou. Association of lactate detection with in-hospital mortality in critically ill patients with acute myocardial infarction: a retrospective cohort study.
BMJ open.
2023 04; 13(4):e069129. doi:
10.1136/bmjopen-2022-069129
. [PMID: 37085300] - Qishan Chen, Hu Li, He Tian, Sin Man Lam, Yilie Liao, Ziyin Zhang, Manyuan Dong, Shaoru Chen, Yuxiao Yao, Jiemiao Meng, Yong Zhang, Lemin Zheng, Zhuo-Xian Meng, Weiping Han, Guanghou Shui, Dahai Zhu, Suneng Fu. Global determination of reaction rates and lipid turnover kinetics in Mus musculus.
Cell metabolism.
2023 04; 35(4):711-721.e4. doi:
10.1016/j.cmet.2023.03.007
. [PMID: 37019081] - Li-Dan Zhou, Yi-Na Lu, Qing Liu, Xue-Mei Shi, Jun Tian. Modulation of TRPV1 function by Citrus reticulata (tangerine) fruit extract for the treatment of sensitive skin.
Journal of cosmetic dermatology.
2023 Apr; 22(4):1369-1376. doi:
10.1111/jocd.15578
. [PMID: 36575892] - Rachel Churm, Liam M Williams, Gareth Dunseath, Sarah L Prior, Richard M Bracken. The polyphenol epigallocatechin gallate lowers circulating catecholamine concentrations and alters lipid metabolism during graded exercise in man: a randomized cross-over study.
European journal of nutrition.
2023 Apr; 62(3):1517-1526. doi:
10.1007/s00394-023-03092-1
. [PMID: 36695951] - Simon Matoori. Vesicular Diagnostics: A Spotlight on Lactate- and Ammonia-Sensing Systems.
ACS applied bio materials.
2023 Mar; ?(?):. doi:
10.1021/acsabm.3c00042
. [PMID: 36917016] - Kari D Pilolla, Jessie Armendariz, Boe M Burrus, David S Baston, Karli A McCarthy, Taylor K Bloedon. Effects of Wild Blueberries on Fat Oxidation Rates in Aerobically Trained Males.
Nutrients.
2023 Mar; 15(6):. doi:
10.3390/nu15061339
. [PMID: 36986069] - Tian Jiang, Ye Song Liang, Yue Gu, Fu Cheng Yao, Yi Fan Liu, Kai Xi Zhang, Fei Biao Song, Jun Long Sun, Jian Luo. Different reoxygenation rates induce different metabolic, apoptotic and immune responses in Golden Pompano (Trachinotus blochii) after hypoxic stress.
Fish & shellfish immunology.
2023 Mar; ?(?):108640. doi:
10.1016/j.fsi.2023.108640
. [PMID: 36871632] - Magdalena Skotniczny, Paweł Satora. Molecular Detection and Identification of Plant-Associated Lactiplantibacillus plantarum.
International journal of molecular sciences.
2023 Mar; 24(5):. doi:
10.3390/ijms24054853
. [PMID: 36902287] - Anas Aljabbari, Abhijeet Girish Lokras, Jacob Judas Kain Kirkensgaard, Thomas Rades, Henrik Franzyk, Aneesh Thakur, Yibang Zhang, Camilla Foged. Elucidating the nanostructure of small interfering RNA-loaded lipidoid-polymer hybrid nanoparticles.
Journal of colloid and interface science.
2023 Mar; 633(?):907-922. doi:
10.1016/j.jcis.2022.11.141
. [PMID: 36508398] - Hunter S Waldman, Andrea R Bryant, Savanna N Knight, Lauren G Killen, Brett A Davis, Marcus A Robinson, Eric K O'Neal. Assessment of Metabolic Flexibility by Substrate Oxidation Responses and Blood Lactate in Women Expressing Varying Levels of Aerobic Fitness and Body Fat.
Journal of strength and conditioning research.
2023 Mar; 37(3):581-588. doi:
10.1519/jsc.0000000000004316
. [PMID: 35836305] - Shirui Ren, Yingming Yang, Mengying Xia, Yalan Deng, Yuling Zuo, Lei Lei, Tao Hu. A Chinese herb preparation, honokiol, inhibits Streptococcus mutans biofilm formation.
Archives of oral biology.
2023 Mar; 147(?):105610. doi:
10.1016/j.archoralbio.2022.105610
. [PMID: 36603516] - Koichi Tanabe, Natsumi Maeda, Honoka Okumura, Jun Shima. Emergence of [GAR+ ] cells in yeast from sake brewing affects the fermentation properties.
Yeast (Chichester, England).
2023 03; 40(3-4):134-142. doi:
10.1002/yea.3844
. [PMID: 36755487] - Nailing Qi, Wentao Ding, Genlai Dong, Zhihui Wang, Shuobo Shi. De novo bio-production of odd-chain fatty acids in Saccharomyces cerevisiae through a synthetic pathway via 3-hydroxypropionic acid.
Biotechnology and bioengineering.
2023 03; 120(3):852-858. doi:
10.1002/bit.28297
. [PMID: 36464776] - Luís Ferraz, Karola Vorauer-Uhl, Michael Sauer, Maria J Sousa, Paola Branduardi. Impact of ergosterol content on acetic and lactic acids toxicity to Saccharomyces cerevisiae.
Yeast (Chichester, England).
2023 03; 40(3-4):152-165. doi:
10.1002/yea.3828
. [PMID: 36380459] - Ariel K Frame, J Wesley Robinson, Nader H Mahmoudzadeh, Jason M Tennessen, Anne F Simon, Robert C Cumming. Aging and memory are altered by genetically manipulating lactate dehydrogenase in the neurons or glia of flies.
Aging.
2023 02; 15(4):947-981. doi:
10.18632/aging.204565
. [PMID: 36849157]