promethazine (BioDeep_00000408932)

Main id: BioDeep_00000002351

 


代谢物信息卡片


Promethazine (oxide)

化学式: C17H20N2S (284.1347)
中文名称: 异丙嗪
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)N(C)C
InChI: InChI=1S/C17H20N2S/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3

描述信息

D - Dermatologicals > D04 - Antipruritics, incl. antihistamines, anesthetics, etc. > D04A - Antipruritics, incl. antihistamines, anesthetics, etc. > D04AA - Antihistamines for topical use
R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use > R06AD - Phenothiazine derivatives
D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists
C78272 - Agent Affecting Nervous System > C267 - Antiemetic Agent > C740 - Phenothiazine
D003879 - Dermatologic Agents > D000982 - Antipruritics
D018926 - Anti-Allergic Agents

同义名列表

3 个代谢物同义名

promethazine; Promethazine (oxide); Promethazine



数据库引用编号

20 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ABCB1, ALB, BCL2, CAT, CYP2D6, MTOR, PIK3CA, PRL, XDH
Peripheral membrane protein 1 MTOR
Endoplasmic reticulum membrane 3 BCL2, CYP2D6, MTOR
Nucleus 5 ALB, BCL2, MPO, MTOR, PRL
cytosol 7 ALB, BCL2, CAT, MTOR, PIK3CA, PRKCQ, XDH
dendrite 1 MTOR
phagocytic vesicle 1 MTOR
centrosome 1 ALB
nucleoplasm 3 MPO, MTOR, PRL
RNA polymerase II transcription regulator complex 1 PRL
Cell membrane 3 ABCB1, HTR3A, TNF
Cytoplasmic side 1 MTOR
Cleavage furrow 1 HTR3A
lamellipodium 1 PIK3CA
Multi-pass membrane protein 5 ABCB1, ATP4A, CACNA1I, HTR3A, NNT
Golgi apparatus membrane 1 MTOR
Synapse 1 HTR3A
cell surface 2 ABCB1, TNF
Golgi apparatus 2 ALB, ATRN
Golgi membrane 2 INS, MTOR
lysosomal membrane 1 MTOR
mitochondrial inner membrane 1 NNT
neuronal cell body 1 TNF
postsynapse 1 HTR3A
Lysosome 2 MPO, MTOR
plasma membrane 10 ABCB1, ATP4A, ATRN, BCHE, CACNA1I, HTR3A, IGHE, PIK3CA, PRKCQ, TNF
Membrane 9 ABCB1, ATP4A, BCL2, CACNA1I, CAT, CYP2D6, HTR3A, MTOR, NNT
apical plasma membrane 2 ABCB1, ATP4A
extracellular exosome 5 ABCB1, ALB, ATRN, CAT, MPO
Lysosome membrane 1 MTOR
endoplasmic reticulum 3 ALB, BCL2, CYP2D6
extracellular space 10 ALB, ATP4A, ATRN, BCHE, IGHE, INS, MPO, PRL, TNF, XDH
perinuclear region of cytoplasm 1 PIK3CA
intercalated disc 1 PIK3CA
mitochondrion 4 BCL2, CAT, CYP2D6, NNT
protein-containing complex 3 ALB, BCL2, CAT
intracellular membrane-bounded organelle 3 CAT, CYP2D6, MPO
Microsome membrane 2 CYP2D6, MTOR
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Single-pass type I membrane protein 2 ATRN, IGHE
Secreted 4 ALB, BCHE, INS, PRL
extracellular region 8 ALB, BCHE, CAT, IGHE, INS, MPO, PRL, TNF
Mitochondrion outer membrane 2 BCL2, MTOR
Single-pass membrane protein 2 BCL2, CYP2D6
mitochondrial outer membrane 2 BCL2, MTOR
[Isoform 2]: Secreted 1 ATRN
mitochondrial matrix 1 CAT
anchoring junction 1 ALB
centriolar satellite 1 PRKCQ
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 1 TNF
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
postsynaptic membrane 1 HTR3A
Apical cell membrane 2 ABCB1, ATP4A
Mitochondrion inner membrane 1 NNT
Matrix side 1 NNT
Membrane raft 1 TNF
pore complex 1 BCL2
focal adhesion 1 CAT
Peroxisome 2 CAT, XDH
sarcoplasmic reticulum 1 XDH
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
Nucleus, PML body 1 MTOR
PML body 1 MTOR
secretory granule 1 MPO
Postsynaptic cell membrane 1 HTR3A
neuron projection 1 HTR3A
ciliary basal body 1 ALB
chromatin 1 PRL
IgE immunoglobulin complex 1 IGHE
phagocytic cup 1 TNF
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 2 ALB, BCHE
serotonin-activated cation-selective channel complex 1 HTR3A
transmembrane transporter complex 1 HTR3A
[Isoform 2]: Cell membrane 1 IGHE
[Isoform 3]: Secreted 1 ATRN
nuclear envelope 1 MTOR
Endomembrane system 1 MTOR
endosome lumen 2 INS, PRL
respiratory chain complex 1 NNT
myelin sheath 1 BCL2
azurophil granule 1 MPO
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 2 CAT, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 ALB, BCHE, INS
platelet alpha granule lumen 1 ALB
voltage-gated calcium channel complex 1 CACNA1I
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
transport vesicle 1 INS
azurophil granule lumen 1 MPO
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
immunological synapse 1 PRKCQ
aggresome 1 PRKCQ
nuclear envelope lumen 1 BCHE
phagocytic vesicle lumen 1 MPO
external side of apical plasma membrane 1 ABCB1
[Isoform 1]: Cell membrane 1 ATRN
Cytoplasmic vesicle, phagosome 1 MTOR
[Isoform 3]: Cell membrane 1 IGHE
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
[Isoform 1]: Secreted 1 IGHE
IgE B cell receptor complex 1 IGHE
immunoglobulin complex, circulating 1 IGHE
catalase complex 1 CAT
BAD-BCL-2 complex 1 BCL2
potassium:proton exchanging ATPase complex 1 ATP4A
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
ciliary transition fiber 1 ALB
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

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