oxiconazole (BioDeep_00000405971)
Main id: BioDeep_00000003163
代谢物信息卡片
化学式: C18H13Cl4N3O (426.98126880000007)
中文名称: 奥昔康唑
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=C(C=C1Cl)Cl)CON=C(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl
InChI: InChI=1S/C18H13Cl4N3O/c19-13-2-1-12(16(21)7-13)10-26-24-18(9-25-6-5-23-11-25)15-4-3-14(20)8-17(15)22/h1-8,11H,9-10H2/b24-18+
描述信息
G - Genito urinary system and sex hormones > G01 - Gynecological antiinfectives and antiseptics > G01A - Antiinfectives and antiseptics, excl. combinations with corticosteroids > G01AF - Imidazole derivatives
D - Dermatologicals > D01 - Antifungals for dermatological use > D01A - Antifungals for topical use > D01AC - Imidazole and triazole derivatives
D000890 - Anti-Infective Agents > D000935 - Antifungal Agents
C254 - Anti-Infective Agent > C514 - Antifungal Agent
同义名列表
1 个代谢物同义名
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:94548
- ChEBI: CHEBI:7825
- KEGG: C08074
- KEGGdrug: D08313
- PubChem: 5353853
- DrugBank: DB00239
- ChEMBL: CHEMBL1262
- CAS: 64211-45-6
- MoNA: FiehnHILIC002211
- MoNA: FiehnHILIC000645
- PubChem: 10274
- NIKKAJI: J19.579K
- RefMet: Oxiconazole
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jinyu Shi, Li Zhou, Hui-Si Huang, Liyuan Peng, Na Xie, Edouard Nice, Li Fu, Cen Jiang, Canhua Huang. Repurposing Oxiconazole against Colorectal Cancer via PRDX2-mediated Autophagy Arrest.
International journal of biological sciences.
2022; 18(9):3747-3761. doi:
10.7150/ijbs.70679. [PMID: 35813474] - Rabab A Mahmoud, Amal K Hussein, Ghada A Nasef, Heba F Mansour. Oxiconazole nitrate solid lipid nanoparticles: formulation, in-vitro characterization and clinical assessment of an analogous loaded carbopol gel.
Drug development and industrial pharmacy.
2020 May; 46(5):706-716. doi:
10.1080/03639045.2020.1752707. [PMID: 32266837] - Hemantkumar A Ranpise, Kishor N Gujar, Dyandevi Mathure, Pooja P Satpute, Rajendra Awasthi, Kamal Dua, Jyotsana R Madan. Skin Targeting of Oxiconazole Nitrate Loaded Nanostructured Lipid- Carrier Gel for Fungal Infections.
Pharmaceutical nanotechnology.
2018; 6(3):192-200. doi:
10.2174/2211738506666180913125918. [PMID: 30210010] - I Benko, F Hernádi, A Megyeri, A Kiss, G Somogyi, Z Tegyey, F Kraicsovits, P Kovács. Comparison of the toxicity of fluconazole and other azole antifungal drugs to murine and human granulocyte-macrophage progenitor cells in vitro.
The Journal of antimicrobial chemotherapy.
1999 May; 43(5):675-81. doi:
10.1093/jac/43.5.675. [PMID: 10382889] - I Harada, K Mitsui, K Uchida, H Yamaguchi. [The in vitro properties of a new hydroxypyridone antimycotic rilopirox, with special reference to its anti-Candida activity].
The Japanese journal of antibiotics.
1999 Feb; 52(2):146-52. doi:
NULL. [PMID: 10221179] - A Polak-Wyss, H Lengsfeld, G Oesterhelt. Effect of oxiconazole and Ro 14-4767/002 on sterol pattern in Candida albicans.
Sabouraudia.
1985 Dec; 23(6):433-41. doi:
10.1080/00362178585380631. [PMID: 3913013] - U Timm, M Zell, L Herzfeld. Sensitive gas-liquid chromatographic method for the determination of oxiconazole in plasma.
Journal of chromatography.
1982 Apr; 229(1):111-20. doi:
10.1016/s0378-4347(00)86042-9. [PMID: 7085818]