Moxifloxacin (BioDeep_00000405909)
natural product
代谢物信息卡片
1-cyclopropyl-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-quinoline-3-carboxylic acid
化学式: C21H24FN3O4 (401.1751)
中文名称: 莫西沙星, 1-环丙基-7-(2,8-二氮杂双环[4.3.0]壬烷-8-基)-6-氟-8-甲氧基-4-氧代喹啉-3-甲酸
谱图信息:
最多检出来源 Escherichia coli(natural_products) 100%
分子结构信息
SMILES: COC1=C2C(=CC(=C1N3CC4CCCNC4C3)F)C(=O)C(=CN2C5CC5)C(=O)O
InChI: InChI=1S/C21H24FN3O4/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24/h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28)/t11-,16+/m0/s1
描述信息
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01M - Quinolone antibacterials > J01MA - Fluoroquinolones
D000970 - Antineoplastic Agents > D059003 - Topoisomerase Inhibitors > D059005 - Topoisomerase II Inhibitors
S - Sensory organs > S01 - Ophthalmologicals > S01A - Antiinfectives > S01AE - Fluoroquinolones
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D024841 - Fluoroquinolones
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
C254 - Anti-Infective Agent > C258 - Antibiotic > C795 - Quinolone Antibiotic
D004791 - Enzyme Inhibitors
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
同义名列表
数据库引用编号
15 个数据库交叉引用编号
- ChEBI: CHEBI:63611
- KEGGdrug: D08237
- PubChem: 152946
- Metlin: METLIN43893
- DrugBank: DB00218
- MeSH: Moxifloxacin
- CAS: 151096-09-2
- CAS: 354812-41-2
- MoNA: CCMSLIB00000081725
- MoNA: FiehnHILIC002113
- MoNA: FiehnHILIC000540
- RefMet: Moxifloxacin
- KEGG: C07663
- PubChem: 9865
- KNApSAcK: 63611
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yuanqin Du, Jingjing Huang, Yaobin Nong, Ruixi Zhong, Ronghuo Zhu, Wenxuan Song, Hongna Huang, Qinwen Tan, Jian Xu, Xiyu Xiao, Juhong Jia. A case of ascetic fluid Mycobacterium aubagnense infection in a patient with severe peritoneal effusion.
BMC infectious diseases.
2023 Feb; 23(1):84. doi:
10.1186/s12879-023-08041-1. [PMID: 36750816] - Alicja Chrzanowska, Dagmara Kurpios-Piec, Barbara Żyżyńska-Granica, Ewelina Kiernozek-Kalińska, Wen Xin Lay, Andrzej K Ciechanowicz, Marta Struga. Anticancer activity and metabolic alteration in colon and prostate cancer cells by novel moxifloxacin conjugates with fatty acids.
European journal of pharmacology.
2023 Feb; 940(?):175481. doi:
10.1016/j.ejphar.2022.175481. [PMID: 36566005] - Haiyan Sun, Xinlou Chai, Guangxun Xu, Shuangying Wei. The Formation and Drug Resistance Mechanism of Biofilm for Streptococcus pneumoniae Infection in Severe Respiratory Patients.
Cellular and molecular biology (Noisy-le-Grand, France).
2023 Jan; 69(1):75-80. doi:
10.14715/cmb/2022.69.1.13. [PMID: 37213152] - Iurii Mochalov, Maryna Kryvtsova, Andrij Chobey, Mariya Kulynych. Identification of Pathogenic Microflora and Its Sensitivity to Antibiotics in Cases of the Odontogenic Purulent Periostitis and Abscesses in the Oral Cavity.
Prague medical report.
2023; 124(1):16-32. doi:
10.14712/23362936.2023.2. [PMID: 36763828] - Merve Eylul Kiymaci, Gizem Ruya Topal, Ozgur Esim, Merve Bacanli, Cansel Kose Ozkan, Onur Erdem, Ayhan Savaser, Yalcin Ozkan. Evaluation of bacterial uptake, antibacterial efficacy against Escherichia coli, and cytotoxic effects of moxifloxacin-loaded solid lipid nanoparticles.
Arhiv za higijenu rada i toksikologiju.
2022 Dec; 73(4):260-269. doi:
10.2478/aiht-2022-73-3667. [PMID: 36607722] - Fatih Donmez, Abdulahad Dogan. Investigation of the effects of three different generations of fluoroquinolone derivatives on antioxidant and immunotoxic enzyme levels in different rat tissues.
Drug and chemical toxicology.
2022 Nov; 45(6):2686-2698. doi:
10.1080/01480545.2021.1982624. [PMID: 34601990] - Prashant D Tailor, Marybeth K Farazdaghi, Sanjay V Patel, Keith H Baratz. Oleander-Associated Keratitis and Uveitis.
Cornea.
2022 Oct; 41(10):1305-1307. doi:
10.1097/ico.0000000000003032. [PMID: 36107850] - Xiaocui Wu, Guangkun Tan, Jinghui Yang, Yinjuan Guo, Chengchen Huang, Wei Sha, Fangyou Yu. Prediction of Mycobacterium tuberculosis drug resistance by nucleotide MALDI-TOF-MS.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.
2022 Aug; 121(?):47-54. doi:
10.1016/j.ijid.2022.04.061. [PMID: 35523300] - Muthumariappan Akilarasan, Elayappan Tamilalagan, Shen-Ming Chen, Selvarasu Maheshwaran, Chih-Hsuan Fan, Mohamed A Habila, Mika Sillanpää. Rational synthesis of rare-earth lanthanum molybdate covered reduced graphene oxide nanocomposites for the voltammetric detection of Moxifloxacin hydrochloride.
Bioelectrochemistry (Amsterdam, Netherlands).
2022 Aug; 146(?):108145. doi:
10.1016/j.bioelechem.2022.108145. [PMID: 35550254] - Xiaocui Wu, Guangkun Tan, Wei Sha, Haican Liu, Jinghui Yang, Yinjuan Guo, Xin Shen, Zheyuan Wu, Hongbo Shen, Fangyou Yu. Use of Whole-Genome Sequencing to Predict Mycobacterium tuberculosis Complex Drug Resistance from Early Positive Liquid Cultures.
Microbiology spectrum.
2022 04; 10(2):e0251621. doi:
10.1128/spectrum.02516-21. [PMID: 35311541] - Carlijn H C Litjens, Laurens F M Verscheijden, Celine Bolwerk, Rick Greupink, Jan B Koenderink, Petra H H van den Broek, Jeroen J M W van den Heuvel, Elin M Svensson, Martin J Boeree, Cecile Magis-Escurra, Wouter Hoefsloot, Reinout van Crevel, Arjan van Laarhoven, Jakko van Ingen, Saskia Kuipers, Rovina Ruslami, David M Burger, Frans G M Russel, Rob E Aarnoutse, Lindsey H M Te Brake. Prediction of Moxifloxacin Concentrations in Tuberculosis Patient Populations by Physiologically Based Pharmacokinetic Modeling.
Journal of clinical pharmacology.
2022 03; 62(3):385-396. doi:
10.1002/jcph.1972. [PMID: 34554580] - Xin Wen, Cong Shen, Jinyu Xia, Lan-Lan Zhong, Zhongwen Wu, Mohamed Abd El-Gawad El-Sayed Ahmed, Nana Long, Furong Ma, Guili Zhang, Wenwei Wu, Jianlve Luo, Yong Xia, Min Dai, Liyan Zhang, Kang Liao, Siyuan Feng, Cha Chen, Yishen Chen, Wenji Luo, Guo-Bao Tian. Whole-Genome Sequencing Reveals the High Nosocomial Transmission and Antimicrobial Resistance of Clostridioides difficile in a Single Center in China, a Four-Year Retrospective Study.
Microbiology spectrum.
2022 02; 10(1):e0132221. doi:
10.1128/spectrum.01322-21. [PMID: 35019676] - Obaidur Rehman, Sudesh Kumar Arya, Ujjwal Prakash Jha, Shifali Nayyar, Itisha Goel. Herpes Zoster Ophthalmicus After COVID-19 Vaccination: Chance Occurrence or More?.
Cornea.
2022 Feb; 41(2):254-256. doi:
10.1097/ico.0000000000002881. [PMID: 34690265] - Josefine Slater, Maiken Stilling, Pelle Hanberg, Mathias Alrø Fichtner Bendtsen, Andrea René Jørgensen, Kjeld Søballe, Nis Pedersen Jørgensen, Mats Bue. Moxifloxacin Concentrations in the Knee Joint, Tibial Bone, and Soft Tissue When Combined with Rifampicin: A Randomized Porcine Microdialysis Study.
The Journal of bone and joint surgery. American volume.
2022 01; 104(1):49-54. doi:
10.2106/jbjs.21.00549. [PMID: 34731098] - Ashit Trivedi, Cheng-Pang Hsu, Pegah Jafarinasabian, Bianca Terminello, Hanze Zhang, Stephen Flach, Samuel Israel, Ashley Brooks, Hongqi Xue, Borje Darpo, Siddique Abbasi, Sandeep Dutta, Edward Lee. Omecamtiv mecarbil does not prolong QTc intervals at therapeutic concentrations.
British journal of clinical pharmacology.
2022 01; 88(1):187-198. doi:
10.1111/bcp.14939. [PMID: 34131942] - Yuan Sun, Ling Cong, Song Yang, Rui Zhao, Zhuoling An, Lihong Liu. Moxifloxacin Induced Liver Injury by Causing Lachnospiraceae Deficiency and Interfering with Butyric Acid Production through Gut-Liver Axis.
Disease markers.
2022; 2022(?):9302733. doi:
10.1155/2022/9302733. [PMID: 35531479] - Atiqah Amran, Ching Yee Tan, Ka-Liong Tan, Ranald Malcom Ho, Anil Kumar Anand, Chuei Wuei Leong. Pharmacokinetics and Bioequivalence Study of a New Branded Generic Moxifloxacin Tablet Among Healthy Volunteers.
Clinical pharmacology in drug development.
2021 12; 10(12):1514-1518. doi:
10.1002/cpdd.964. [PMID: 34107173] - Salma Luaiby Dahash, Salah Burhan Al-Windy, Azhar Hatif Al-Kuraishi, Nawar Raad Hussien, Marwa Salih Al-Niemi, Hayder Mutter Al-Kuraishy. Ellagic acid-rich Pomegranate extracts synergizes moxifloxacin against methicillin resistance Staphylococcus aureus (MRSA).
JPMA. The Journal of the Pakistan Medical Association.
2021 Dec; 71(Suppl 8)(12):S88-S92. doi:
". [PMID: 35130226] - Mahwish Akhtar, Somia Gul, Sana Shamim, Rubina Siddiqui. Simultaneous determination of moxifloxacin with NSAIDs in API, dosage and serum by reverse phase high-performance liquid chromatography: Application to in vitro drug interactions.
Pakistan journal of pharmaceutical sciences.
2021 Nov; 34(6):2091-2099. doi:
NULL. [PMID: 35034869] - Lloyd Tanner, Gabriel T Mashabela, Charles C Omollo, Timothy J de Wet, Christopher J Parkinson, Digby F Warner, Richard K Haynes, Lubbe Wiesner. Intracellular Accumulation of Novel and Clinically Used TB Drugs Potentiates Intracellular Synergy.
Microbiology spectrum.
2021 10; 9(2):e0043421. doi:
10.1128/spectrum.00434-21. [PMID: 34585951] - George P Allen, Kristina M Deao, Stephanie A Hill, Sandra M Schipelliti, Thomas Tran. In vitro evaluation of antimicrobial resistance selection in Neisseria gonorrhoeae.
International journal of antimicrobial agents.
2021 Oct; 58(4):106417. doi:
10.1016/j.ijantimicag.2021.106417. [PMID: 34391903] - Rita M Pinto, Claudia Monteiro, Sofia A Costa Lima, Susana Casal, Patrick Van Dijck, M Cristina L Martins, Cláudia Nunes, Salette Reis. N-Acetyl-l-cysteine-Loaded Nanosystems as a Promising Therapeutic Approach Toward the Eradication of Pseudomonas aeruginosa Biofilms.
ACS applied materials & interfaces.
2021 Sep; 13(36):42329-42343. doi:
10.1021/acsami.1c05124. [PMID: 34464076] - Ramesh Boinpally, Brian McNamee, Li Yao, Matthew Butler, Danielle McGeeney, Lisa Borbridge, Antonia Periclou. A Single Supratherapeutic Dose of Atogepant Does Not Affect Cardiac Repolarization in Healthy Adults: Results From a Randomized, Single-Dose, Phase 1 Crossover Trial.
Clinical pharmacology in drug development.
2021 09; 10(9):1099-1107. doi:
10.1002/cpdd.940. [PMID: 33942560] - Sudhakar M Pai, Hiroyuki Yamada, Robert B Kleiman, Rui Zhuo, Qingtao Mike Huang, Ryosuke Koretomo. Thorough QT/QTc Evaluation of the Cardiac Safety of Enarodustat (JTZ-951), an Oral Erythropoiesis-Stimulating Agent, in Healthy Adults.
Clinical pharmacology in drug development.
2021 08; 10(8):884-898. doi:
10.1002/cpdd.933. [PMID: 34159762] - Gang Fang, Ning-Chang Cheng, Li-Li Huang, Wei-Ping Xie, Chun-Mei Hu, Wei Chen. The first report of co-existence of pulmonary tuberculosis and lung malignancy in a kidney transplant recipient: a case report and literature review.
BMC infectious diseases.
2021 Jul; 21(1):629. doi:
10.1186/s12879-021-06350-x. [PMID: 34210287] - Li Yu, Congcong Yan, Shanshan Chu, Yingjun Chen, Junwei Wang. The differential diagnosis of pneumonia in two patients infected by atypical pathogens.
Future microbiology.
2021 07; 16(11):769-776. doi:
10.2217/fmb-2021-0127. [PMID: 34253052] - Lei Tang, Xianchun Zeng. One-year Follow-up after Severe SARS-CoV-2 Pneumonia.
Radiology.
2021 07; 300(1):E310. doi:
10.1148/radiol.2021210615. [PMID: 33787340] - Jinju Guk, Jérémie Guedj, Charles Burdet, Antoine Andremont, Jean de Gunzburg, Annie Ducher, France Mentré. Modeling the Effect of DAV132, a Novel Colon-Targeted Adsorbent, on Fecal Concentrations of Moxifloxacin and Gut Microbiota Diversity in Healthy Volunteers.
Clinical pharmacology and therapeutics.
2021 04; 109(4):1045-1054. doi:
10.1002/cpt.1977. [PMID: 32617960] - Zeynep Kayaarasi Ozturker. Conjunctivitis as sole symptom of COVID-19: A case report and review of literature.
European journal of ophthalmology.
2021 Mar; 31(2):NP161-NP166. doi:
10.1177/1120672120946287. [PMID: 32703010] - Ting Hu, Yuan Sun, Han Li, Ping Du, Lihong Liu, Zhuoling An. Dual derivatization strategy for the comprehensive quantification and double bond location characterization of fatty acids by ultra-high performance liquid chromatography-tandem mass spectrometry.
Journal of chromatography. A.
2021 Feb; 1639(?):461939. doi:
10.1016/j.chroma.2021.461939. [PMID: 33530009] - Erkan Ozcan, Serap Yavuzer, Betul Borku Uysal, Mehmet Sami Islamoglu, Hande Ikitimur, Omer Faruk Unal, Yunus Emre Akpinar, Serhat Seyhan, Suna Koc, Hakan Yavuzer, Mahir Cengiz. The relationship between positivity for COVID-19 RT-PCR and symptoms, clinical findings, and mortality in Turkey.
Expert review of molecular diagnostics.
2021 02; 21(2):245-250. doi:
10.1080/14737159.2021.1882305. [PMID: 33496627] - Dong Liang, Jing Ma, Bo Wei. Oral absorption and drug interaction kinetics of moxifloxacin in an animal model of weightlessness.
Scientific reports.
2021 01; 11(1):2605. doi:
10.1038/s41598-021-82044-3. [PMID: 33510326] - Lichao Fan, Huan Liu, Na Li, Chang Liu, Ye Gu, Yongyu Liu, Yu Chen. Medical treatment of 55 patients with COVID-19 from seven cities in northeast China who fully recovered: A single-center, retrospective, observational study.
Medicine.
2021 Jan; 100(2):e23923. doi:
10.1097/md.0000000000023923. [PMID: 33466134] - Tingyu Yan, Zhongxu Ma, Jingjing Liu, Na Yin, Shizhen Lei, Xinxin Zhang, Xuedong Li, Yu Zhang, Jun Kong. Thermoresponsive GenisteinNLC-dexamethasone-moxifloxacin multi drug delivery system in lens capsule bag to prevent complications after cataract surgery.
Scientific reports.
2021 01; 11(1):181. doi:
10.1038/s41598-020-80476-x. [PMID: 33420301] - Stacey L P Scroggs, Danielle K Offerdahl, Dylan P Flather, Ciera N Morris, Benjamin L Kendall, Rebecca M Broeckel, Paul A Beare, Marshall E Bloom. Fluoroquinolone Antibiotics Exhibit Low Antiviral Activity against SARS-CoV-2 and MERS-CoV.
Viruses.
2020 12; 13(1):. doi:
10.3390/v13010008. [PMID: 33374514] - Yaguang Hu, Tianyan Chen, Miaomiao Liu, Li Zhang, Fang Wang, Shuo Zhao, Hui Liu, Han Xia, Yawen Wang, Li Li. Positive detection of SARS-CoV-2 combined HSV1 and HHV6B virus nucleic acid in tear and conjunctival secretions of a non-conjunctivitis COVID-19 patient with obstruction of common lacrimal duct.
Acta ophthalmologica.
2020 Dec; 98(8):859-863. doi:
10.1111/aos.14456. [PMID: 32406606] - Shaojia Lu, Ning Wei, Jiajun Jiang, Lingling Wu, Jifang Sheng, Jianying Zhou, Qiang Fang, Yu Chen, Shufa Zheng, Feng Chen, Tingbo Liang, Shaohua Hu. First report of manic-like symptoms in a COVID-19 patient with no previous history of a psychiatric disorder.
Journal of affective disorders.
2020 12; 277(?):337-340. doi:
10.1016/j.jad.2020.08.031. [PMID: 32858315] - Krzysztof Marciniec, Artur Beberok, Paweł Pęcak, Stanisław Boryczka, Dorota Wrześniok. Ciprofloxacin and moxifloxacin could interact with SARS-CoV-2 protease: preliminary in silico analysis.
Pharmacological reports : PR.
2020 Dec; 72(6):1553-1561. doi:
10.1007/s43440-020-00169-0. [PMID: 33063271] - Zhi Xu. 1,2,3-Triazole-containing hybrids with potential antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA).
European journal of medicinal chemistry.
2020 Nov; 206(?):112686. doi:
10.1016/j.ejmech.2020.112686. [PMID: 32795773] - Katarina Ilic, Ivy Song, Jingyang Wu, Patrick Martin. Evaluation of the Effect of Maribavir on Cardiac Repolarization in Healthy Participants: Thorough QT/QTc Study.
Clinical and translational science.
2020 11; 13(6):1260-1270. doi:
10.1111/cts.12814. [PMID: 32506738] - Valeria Tellone, Maria Teresa Rosignoli, Rossella Picollo, Patrizia Dragone, Alessandra Del Vecchio, Alessandro Comandini, Milko Radicioni, Chiara Leuratti, Fabrizio Calisti. Effect of 3 Single Doses of Trazodone on QTc Interval in Healthy Subjects.
Journal of clinical pharmacology.
2020 11; 60(11):1483-1495. doi:
10.1002/jcph.1640. [PMID: 32488885] - Jennifer S McDaniel, Laura L F Scott, Jennifer Rebeles, Gregory T Bramblett, Elof Eriksson, Anthony J Johnson, Gina L Griffith. Treatment of Corneal Infections Utilizing an Ocular Wound Chamber.
Translational vision science & technology.
2020 11; 9(12):4. doi:
10.1167/tvst.9.12.4. [PMID: 33200046] - Defang Ding, Caisong Zhu, Weiwu Yao. A Cured Patient With 2019-nCoV Pneumonia.
The American journal of medicine.
2020 11; 133(11):1291-1292. doi:
10.1016/j.amjmed.2020.02.023. [PMID: 32205073] - Azmi Nasser, Shamia L Faison, Tesfaye Liranso, Toyin Adewole, Gregory D Busse, Maurizio Fava, Robert B Kleiman, Stefan Schwabe. Evaluation of the Effect of SPN-812 (Viloxazine Extended-Release) on QTc Interval in Healthy Adults.
The Journal of clinical psychiatry.
2020 10; 81(6):. doi:
10.4088/jcp.20m13395. [PMID: 33049804] - Irene Karampela, Maria Dalamaga. Could Respiratory Fluoroquinolones, Levofloxacin and Moxifloxacin, Prove to be Beneficial as an Adjunct Treatment in COVID-19?.
Archives of medical research.
2020 10; 51(7):741-742. doi:
10.1016/j.arcmed.2020.06.004. [PMID: 32546446] - Li-Yu Liang, Ying-Chun He, Yun-Fei Li, Juan Yang, Feng-Yan Xu, Lu-Jin Li, Ji-Han Huang, Kun Wang, Qing-Shan Zheng. Relationship between antofloxacin concentration and QT prolongation and estimation of the possible false-positive rate.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2020 Oct; 130(?):110619. doi:
10.1016/j.biopha.2020.110619. [PMID: 32795925] - Svetlana N Kondratenko, Irina V Zolkina, Eugenia V Shikh. A study of the pharmacokinetics of moxifloxacin by the dynamics of its distribution in the blood plasma and saliva of healthy volunteers: a comparative analysis and possible extrapolation methods.
Drug metabolism and personalized therapy.
2020 09; 35(4):. doi:
10.1515/dmpt-2020-0115. [PMID: 34704694] - Feng He, Qingqing Luo, Ming Lei, Lixin Fan, Xinning Shao, Kaiyuan Hu, Shuguang Qin, Na Yu, Jie Cao, Liuping Yang. Successful recovery of recurrence of positive SARS-CoV-2 RNA in COVID-19 patient with systemic lupus erythematosus: a case report and review.
Clinical rheumatology.
2020 Sep; 39(9):2803-2810. doi:
10.1007/s10067-020-05230-0. [PMID: 32725351] - K Iqbal, A Broeker, H Nowak, T Rahmel, A Nussbaumer-Pröll, Z Österreicher, M Zeitlinger, S G Wicha. A pharmacometric approach to define target site-specific breakpoints for bacterial killing and resistance suppression integrating microdialysis, time-kill curves and heteroresistance data: a case study with moxifloxacin.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.
2020 Sep; 26(9):1255.e1-1255.e8. doi:
10.1016/j.cmi.2020.02.013. [PMID: 32088331] - Ming-Cheng Chang, Yu-Jen Kuo, Kuo-Hsuan Hung, Cheng-Liang Peng, Kuan-Yin Chen, Lung-Kun Yeh. Liposomal dexamethasone-moxifloxacin nanoparticle combinations with collagen/gelatin/alginate hydrogel for corneal infection treatment and wound healing.
Biomedical materials (Bristol, England).
2020 08; 15(5):055022. doi:
10.1088/1748-605x/ab9510. [PMID: 32434164] - Kui Zhang, Maolu Tian, Yang Zeng, Linwen Wang, Sha Luo, Wei Xia, Xiangyan Zhang, Yan Zha. The combined therapy of a traditional Chinese medicine formula and Western medicine for a critically ill case infected with COVID-19.
Complementary therapies in medicine.
2020 Aug; 52(?):102473. doi:
10.1016/j.ctim.2020.102473. [PMID: 32951723] - Josefine Slater, Pelle Hanberg, Mathias Alrø Fichtner Bendtsen, Andrea René Jørgensen, Eva Greibe, Kjeld Søballe, Mats Bue, Nis Pedersen Jørgensen, Maiken Stilling. Effects of rifampicin on moxifloxacin concentrations in porcine cervical spine: a randomized microdialysis study.
The Journal of antimicrobial chemotherapy.
2020 08; 75(8):2206-2212. doi:
10.1093/jac/dkaa153. [PMID: 32413120] - Bhagabat Nayak, Chanchal Poddar, Manoj Kumar Panigrahi, Swagata Tripathy, Baijayantimala Mishra. Late manifestation of follicular conjunctivitis in ventilated patient following COVID-19 positive severe pneumonia.
Indian journal of ophthalmology.
2020 Aug; 68(8):1675-1677. doi:
10.4103/ijo.ijo_1682_20. [PMID: 32709820] - Marcela Krutova, Vaclav Capek, Elka Nycova, Sabina Vojackova, Magda Balejova, Lenka Geigerova, Renata Tejkalova, Lenka Havlinova, Iva Vagnerova, Pavel Cermak, Lenka Ryskova, Petr Jezek, Dana Zamazalova, Denisa Vesela, Alice Kucharova, Dana Nemcova, Martina Curdova, Otakar Nyc, Pavel Drevinek. The association of a reduced susceptibility to moxifloxacin in causative Clostridium (Clostridioides) difficile strain with the clinical outcome of patients.
Antimicrobial resistance and infection control.
2020 06; 9(1):98. doi:
10.1186/s13756-020-00765-y. [PMID: 32605598] - Yanmin Guan, Yong Liu. Meta-analysis on Effectiveness and Safety of Moxifloxacin in Treatment of Multidrug Resistant Tuberculosis in Adults.
Medicine.
2020 Jun; 99(25):e20648. doi:
10.1097/md.0000000000020648. [PMID: 32569195] - Lei Sun, Sergey Yagoda, Hongqi Xue, Randy Brown, Narinder Nangia, David McDonnell, Bhaskar Rege, Lisa von Moltke, Borje Darpo. Combination of olanzapine and samidorphan has no clinically relevant effects on ECG parameters, including the QTc interval: Results from a phase 1 QT/QTc study.
Progress in neuro-psychopharmacology & biological psychiatry.
2020 06; 100(?):109881. doi:
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Journal of medical virology.
2020 06; 92(6):683-687. doi:
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Journal of medical virology.
2020 06; 92(6):529-530. doi:
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The American journal of tropical medicine and hygiene.
2020 06; 102(6):1210-1213. doi:
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Journal of pharmaceutical and biomedical analysis.
2020 May; 183(?):113137. doi:
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Clinical pharmacology in drug development.
2020 05; 9(4):456-465. doi:
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Chemistry and physics of lipids.
2020 05; 228(?):104891. doi:
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Acta medica Indonesiana.
2020 Apr; 52(2):163-171. doi:
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Clinical pharmacology in drug development.
2020 04; 9(3):307-320. doi:
10.1002/cpdd.749. [PMID: 31777203] - Bo Zhou, Bowen Lou, Junhui Liu, Jianqing She. Serum metabolite profiles as potential biochemical markers in young adults with community-acquired pneumonia cured by moxifloxacin therapy.
Scientific reports.
2020 03; 10(1):4436. doi:
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Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.
2020 Mar; 36(3):361-366. doi:
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Journal of veterinary pharmacology and therapeutics.
2020 Mar; 43(2):108-114. doi:
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Current topics in medicinal chemistry.
2020; 20(16):1461-1467. doi:
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Bioorganic & medicinal chemistry.
2019 12; 27(23):115151. doi:
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Clinical and translational science.
2019 11; 12(6):687-697. doi:
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Antimicrobial agents and chemotherapy.
2019 10; 63(10):. doi:
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Journal of clinical pharmacology.
2019 10; 59(10):1405-1414. doi:
10.1002/jcph.1445. [PMID: 31111505] - Hanbin Li, David H Salinger, Daniel Everitt, Mengchun Li, Angelo Del Parigi, Carl Mendel, Jerry R Nedelman. Long-Term Effects on QT Prolongation of Pretomanid Alone and in Combinations in Patients with Tuberculosis.
Antimicrobial agents and chemotherapy.
2019 10; 63(10):. doi:
10.1128/aac.00445-19. [PMID: 31358590] - Charles Burdet, Thu Thuy Nguyen, Xavier Duval, Stéphanie Ferreira, Antoine Andremont, Jérémie Guedj, France Mentré. Impact of Antibiotic Gut Exposure on the Temporal Changes in Microbiome Diversity.
Antimicrobial agents and chemotherapy.
2019 10; 63(10):. doi:
10.1128/aac.00820-19. [PMID: 31307985] - Valerie M Vaughn, Tejal Gandhi, Anna Conlon, Vineet Chopra, Anurag N Malani, Scott A Flanders. The Association of Antibiotic Stewardship With Fluoroquinolone Prescribing in Michigan Hospitals: A Multi-hospital Cohort Study.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
2019 09; 69(8):1269-1277. doi:
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Journal of pharmaceutical sciences.
2019 09; 108(9):2905-2916. doi:
10.1016/j.xphs.2019.04.005. [PMID: 30978345] - Hartmuth Nowak, Caroline Weidemann, Stefan Martini, Zoe Anne Oesterreicher, Christoph Dorn, Michael Adamzik, Frieder Kees, Markus Zeitlinger, Tim Rahmel. Repeated determination of moxifloxacin concentrations in interstitial space fluid of muscle and subcutis in septic patients.
The Journal of antimicrobial chemotherapy.
2019 09; 74(9):2681-2689. doi:
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Clinical therapeutics.
2019 09; 41(9):1724-1736.e4. doi:
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Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia.
2019 Aug; 32(4):327-332. doi:
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Journal of clinical pharmacology.
2019 05; 59(5):654-667. doi:
10.1002/jcph.1358. [PMID: 30681729] - Jansy Sarathy, Landry Blanc, Nadine Alvarez-Cabrera, Paul O'Brien, Isabela Dias-Freedman, Marizel Mina, Matthew Zimmerman, Firat Kaya, Hsin-Pin Ho Liang, Brendan Prideaux, Jillian Dietzold, Padmini Salgame, Radojka M Savic, Jennifer Linderman, Denise Kirschner, Elsje Pienaar, Véronique Dartois. Fluoroquinolone Efficacy against Tuberculosis Is Driven by Penetration into Lesions and Activity against Resident Bacterial Populations.
Antimicrobial agents and chemotherapy.
2019 05; 63(5):. doi:
10.1128/aac.02516-18. [PMID: 30803965] - Wei Zhang, Shichun Lun, Ling-Ling Liu, Shiqi Xiao, Guanfu Duan, Hendra Gunosewoyo, Fan Yang, Jie Tang, William R Bishai, Li-Fang Yu. Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis. Part II.
Journal of medicinal chemistry.
2019 04; 62(7):3575-3589. doi:
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International wound journal.
2019 Apr; 16(2):503-510. doi:
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Current microbiology.
2019 Apr; 76(4):520-526. doi:
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Nanomedicine : nanotechnology, biology, and medicine.
2019 04; 17(?):124-136. doi:
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European journal of medicinal chemistry.
2019 Mar; 166(?):108-118. doi:
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International journal of chronic obstructive pulmonary disease.
2019; 14(?):1923-1932. doi:
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Antimicrobial agents and chemotherapy.
2018 12; 62(12):. doi:
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Arquivos brasileiros de oftalmologia.
2018 Nov; 81(6):510-513. doi:
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Die Pharmazie.
2018 11; 73(11):625-629. doi:
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Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi.
2018 Oct; 51(5):681-687. doi:
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Antimicrobial agents and chemotherapy.
2018 10; 62(10):. doi:
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Lancet (London, England).
2018 09; 392(10150):821-834. doi:
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Journal of pharmacological and toxicological methods.
2018 Sep; 93(?):75-79. doi:
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Journal of pharmaceutical and biomedical analysis.
2018 Aug; 157(?):92-99. doi:
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Journal of clinical pharmacology.
2018 07; 58(7):952-964. doi:
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The Cochrane database of systematic reviews.
2018 05; 5(?):CD011680. doi:
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Antimicrobial agents and chemotherapy.
2018 05; 62(5):. doi:
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Journal of pharmaceutical and biomedical analysis.
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