Desaminotyrosine (BioDeep_00000405517)

Main id: BioDeep_00000001224

 

PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


3-(4-Hydroxyphenyl)propionic acid

化学式: C9H10O3 (166.063)
中文名称: 对羟基苯丙酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=C(C=CC(=C1)O)CCC(O)=O
InChI: InChI=1S/C9H10O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-2,4-5,10H,3,6H2,(H,11,12)

描述信息

Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling.
Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling.

同义名列表

3 个代谢物同义名

3-(4-Hydroxyphenyl)propionic acid; Desaminotyrosine; Phloretate



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

26 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ALB, ANG, CAT, DHFR, ELANE, GNAT3, MYLK, TUBB4B, TYR
Endosome membrane 2 INSR, TF
Nucleus 3 ALB, ANG, TUBB4B
cytosol 7 ALB, ANG, CAT, DHFR, ELANE, MYLK, TUBB4B
phagocytic vesicle 1 ELANE
centrosome 1 ALB
Cell membrane 2 INSR, TNF
Cleavage furrow 1 MYLK
lamellipodium 1 MYLK
Synapse 1 MYLK
cell surface 3 ELANE, TF, TNF
Golgi apparatus 1 ALB
Golgi membrane 1 INS
growth cone 1 ANG
lysosomal membrane 2 EGF, GAA
neuronal cell body 2 ANG, TNF
Lysosome 3 GAA, INSR, TYR
acrosomal vesicle 1 GNAT3
plasma membrane 8 EGF, GAA, GNAT3, INSR, KNG1, MYLK, TF, TNF
terminal bouton 1 GHRH
Membrane 4 CAT, EGF, GAA, INSR
apical plasma membrane 2 GNAT3, TF
axon 1 INSR
caveola 1 INSR
extracellular exosome 11 ALB, BMP3, CAT, EGF, ELANE, GAA, INSR, KNG1, LYZ, TF, TUBB4B
Lysosome membrane 1 GAA
endoplasmic reticulum 1 ALB
extracellular space 11 ALB, ANG, BMP3, EGF, ELANE, GHRH, INS, KNG1, LYZ, TF, TNF
lysosomal lumen 1 GAA
perinuclear region of cytoplasm 2 TF, TYR
mitochondrion 2 CAT, DHFR
protein-containing complex 3 ALB, CAT, GNAT3
intracellular membrane-bounded organelle 3 CAT, GAA, TYR
Single-pass type I membrane protein 2 INSR, TYR
Secreted 6 ALB, ANG, BMP3, GAA, INS, TF
extracellular region 15 ALB, ANG, BMP3, CAT, EGF, ELANE, ELN, GAA, GHRH, INS, KNG1, LYZ, TF, TNF, TUBB4B
basal part of cell 1 TF
neuronal cell body membrane 1 INSR
mitochondrial matrix 1 CAT
anchoring junction 1 ALB
photoreceptor inner segment 1 GNAT3
photoreceptor outer segment 1 GNAT3
external side of plasma membrane 2 INSR, TNF
Extracellular vesicle 1 TUBB4B
Secreted, extracellular space, extracellular matrix 1 ELN
actin cytoskeleton 2 ANG, MYLK
perikaryon 1 GHRH
cytoplasmic vesicle 1 TF
microtubule cytoskeleton 1 TUBB4B
nucleolus 1 ANG
Melanosome membrane 1 TYR
Early endosome 1 TF
clathrin-coated pit 1 TF
Golgi-associated vesicle 1 TYR
recycling endosome 2 TF, TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 TF
Cell projection, lamellipodium 1 MYLK
Membrane raft 1 TNF
Cytoplasm, cytoskeleton 1 TUBB4B
focal adhesion 1 CAT
microtubule 1 TUBB4B
extracellular matrix 1 ELN
Peroxisome 1 CAT
basement membrane 1 ANG
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 3 ELANE, ELN, KNG1
secretory granule 1 ELANE
axoneme 1 GNAT3
Late endosome 2 INSR, TF
receptor complex 1 INSR
ciliary basal body 1 ALB
phagocytic cup 1 TNF
mitotic spindle 1 TUBB4B
Chromosome 1 ANG
cytoskeleton 1 TUBB4B
centriole 1 ALB
Secreted, extracellular space 1 KNG1
Nucleus, nucleolus 1 ANG
spindle pole 1 ALB
blood microparticle 3 ALB, KNG1, TF
intercellular bridge 1 TUBB4B
Cytoplasm, cytoskeleton, flagellum axoneme 1 TUBB4B
sperm flagellum 1 TUBB4B
endosome lumen 1 INS
axonemal microtubule 1 TUBB4B
heterotrimeric G-protein complex 1 GNAT3
tertiary granule membrane 1 GAA
Melanosome 1 TYR
Cytoplasm, Stress granule 1 ANG
cytoplasmic stress granule 1 ANG
stress fiber 1 MYLK
basal plasma membrane 1 TF
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 3 CAT, INS, TF
HFE-transferrin receptor complex 1 TF
Golgi lumen 1 INS
endoplasmic reticulum lumen 4 ALB, INS, KNG1, TF
transcription repressor complex 1 ELANE
platelet alpha granule lumen 3 ALB, EGF, KNG1
specific granule lumen 2 ELANE, LYZ
tertiary granule lumen 1 LYZ
endocytic vesicle 2 ANG, TF
transport vesicle 1 INS
azurophil granule membrane 1 GAA
azurophil granule lumen 3 ELANE, LYZ, TUBB4B
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
clathrin-coated endocytic vesicle membrane 2 EGF, TF
Cytoplasm, cytoskeleton, stress fiber 1 MYLK
ficolin-1-rich granule membrane 1 GAA
dendrite membrane 1 INSR
Cytoplasmic vesicle, phagosome 1 ELANE
vesicle coat 1 TF
elastic fiber 1 ELN
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
angiogenin-PRI complex 1 ANG
catalase complex 1 CAT
insulin receptor complex 1 INSR
autolysosome lumen 1 GAA
ciliary transition fiber 1 ALB
dense body 1 TF
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Qianwen Wang, Zhifeng Fang, Yue Xiao, Hongchao Wang, Pinghu Zhang, Wenwei Lu, Hao Zhang, Xiuwen Zhou. Lactiplantibacillus pentoses CCFM1227 Produces Desaminotyrosine to Protect against Influenza Virus H1N1 Infection through the Type I Interferon in Mice. Nutrients. 2023 Aug; 15(16):. doi: 10.3390/nu15163659. [PMID: 37630849]
  • Ibrahim E Sallam, Ulrike Rolle-Kampczyk, Stephanie Serena Schäpe, Soumaya S Zaghloul, Riham S El-Dine, Ping Shao, Martin von Bergen, Mohamed A Farag. Evaluation of Antioxidant Activity and Biotransformation of Opuntia Ficus Fruit: The Effect of In Vitro and Ex Vivo Gut Microbiota Metabolism. Molecules (Basel, Switzerland). 2022 Nov; 27(21):. doi: 10.3390/molecules27217568. [PMID: 36364395]
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  • Feng Li, Liping Wang, Yilei Cai, Yihuo Luo, Xianai Shi. Safety assessment of desaminotyrosine: Acute, subchronic oral toxicity, and its effects on intestinal microbiota in rats. Toxicology and applied pharmacology. 2021 04; 417(?):115464. doi: 10.1016/j.taap.2021.115464. [PMID: 33636197]
  • Xianyu Liang, Fan Liu, Yiqun Wan, Xiaoying Yin, Weiting Liu. Facile synthesis of molecularly imprinted polymers for selective extraction of tyrosine metabolites in human urine. Journal of chromatography. A. 2019 Feb; 1587(?):34-41. doi: 10.1016/j.chroma.2018.12.014. [PMID: 30551942]
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