benzocaine (BioDeep_00000402542)

Main id: BioDeep_00000001866

 


代谢物信息卡片


benzocaine

化学式: C9H11NO2 (165.0789746)
中文名称: 对氨基苯甲酸乙酯
谱图信息: 最多检出来源 Bos taurus(endogenous) 86%

分子结构信息

SMILES: CCOC(=O)C1=CC=C(C=C1)N
InChI: InChI=1S/C9H11NO2/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6H,2,10H2,1H3

描述信息

D - Dermatologicals > D04 - Antipruritics, incl. antihistamines, anesthetics, etc. > D04A - Antipruritics, incl. antihistamines, anesthetics, etc. > D04AB - Anesthetics for topical use
C - Cardiovascular system > C05 - Vasoprotectives > C05A - Agents for treatment of hemorrhoids and anal fissures for topical use > C05AD - Local anesthetics
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D000777 - Anesthetics
R - Respiratory system > R02 - Throat preparations > R02A - Throat preparations > R02AD - Anesthetics, local
N - Nervous system > N01 - Anesthetics > N01B - Anesthetics, local > N01BA - Esters of aminobenzoic acid
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
C78272 - Agent Affecting Nervous System > C245 - Anesthetic Agent
CONFIDENCE standard compound; INTERNAL_ID 1023; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10012; ORIGINAL_PRECURSOR_SCAN_NO 10007
CONFIDENCE standard compound; INTERNAL_ID 1023; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10042; ORIGINAL_PRECURSOR_SCAN_NO 10037
CONFIDENCE standard compound; INTERNAL_ID 1023; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10067; ORIGINAL_PRECURSOR_SCAN_NO 10063
CONFIDENCE standard compound; INTERNAL_ID 1023; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10090; ORIGINAL_PRECURSOR_SCAN_NO 10086
CONFIDENCE standard compound; INTERNAL_ID 1023; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10098; ORIGINAL_PRECURSOR_SCAN_NO 10094
CONFIDENCE standard compound; INTERNAL_ID 2726
CONFIDENCE standard compound; INTERNAL_ID 8623
CONFIDENCE standard compound; INTERNAL_ID 8273

同义名列表

1 个代谢物同义名

benzocaine



数据库引用编号

29 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Lin Fang Long, Qi Fang Zhao, Fu Long Zhang, Ran Tang, Jia Bao Wei, Shan Guan, Yan Chen. Inhibitory effect of benzocaine from Schisandra chinensis on Alternaria alternata. Scientific reports. 2024 03; 14(1):6691. doi: 10.1038/s41598-024-57237-1. [PMID: 38509170]
  • Hery Mitsutake, Gustavo H Rodrigues da Silva, Eneida de Paula, Márcia C Breitkreitz. When it is too much: Identifying butamben excess on the surface of pharmaceutical preformulation samples by Raman mapping. Journal of pharmaceutical and biomedical analysis. 2023 Oct; 235(?):115644. doi: 10.1016/j.jpba.2023.115644. [PMID: 37633164]
  • Xiangli He, Jiayan Cui, Hui Ma, Naijipu Abuduaini, Ying Huang, Lu Tang, Wanyan Wang, Yuanyuan Zhang, Yang Wang, Weiqiang Lu, Bo Feng, Jin Huang. Berberrubine is a novel and selective IMPDH2 inhibitor that impairs the growth of colorectal cancer. Biochemical pharmacology. 2023 Oct; 218(?):115868. doi: 10.1016/j.bcp.2023.115868. [PMID: 37871880]
  • Jia-Yi Zheng, Xiao-Xiao Li, Wei-Yao Lin, Shan Su, Hai-Cui Wu, Rui-Dan Hu, Hua-Feng Pan, Jiang-Hong Ye, Ye-Feng Cai, Shi-Jie Zhang. Huang-Lian-Jie-Du decoction alleviates depressive-like behaviors in dextran sulfate sodium-induced colitis mice via Trem2/Dap12 pathway. Journal of ethnopharmacology. 2023 May; ?(?):116658. doi: 10.1016/j.jep.2023.116658. [PMID: 37263316]
  • Yonger Chen, Shumin Zhu, Zongwen Chen, Ying Liu, Chaoying Pei, Haiyang Huang, Shaozhen Hou, Weimin Ning, Jian Liang. Gingerenone A Alleviates Ferroptosis in Secondary Liver Injury in Colitis Mice via Activating Nrf2-Gpx4 Signaling Pathway. Journal of agricultural and food chemistry. 2022 Oct; 70(39):12525-12534. doi: 10.1021/acs.jafc.2c05262. [PMID: 36135333]
  • Chen Huang, Yuqin Wang, Xiao Lin, Ting Fung Chan, Keng Po Lai, Rong Li. Uncovering the functions of plasma proteins in ulcerative colitis and identifying biomarkers for BPA-induced severe ulcerative colitis: A plasma proteome analysis. Ecotoxicology and environmental safety. 2022 Sep; 242(?):113897. doi: 10.1016/j.ecoenv.2022.113897. [PMID: 35999755]
  • Keita Adachi, Michiyasu Ishizawa, Shigeyuki Uno, Hitomi Kubota, Takuo Henmi, Tsugumichi Koshinaga, Makoto Makishima, Kenichi Sakurai. Oral benzo[a]pyrene administration attenuates dextran sulfate sodium-induced colitis in mice. Chemico-biological interactions. 2022 Feb; 353(?):109802. doi: 10.1016/j.cbi.2022.109802. [PMID: 34998820]
  • Yong-Er Chen, Shi-Jie Xu, Ying-Yu Lu, Shu-Xian Chen, Xian-Hua Du, Shao-Zhen Hou, Hai-Yang Huang, Jian Liang. Asperuloside suppressing oxidative stress and inflammation in DSS-induced chronic colitis and RAW 264.7 macrophages via Nrf2/HO-1 and NF-κB pathways. Chemico-biological interactions. 2021 Aug; 344(?):109512. doi: 10.1016/j.cbi.2021.109512. [PMID: 33974900]
  • Gustavo H Rodrigues da Silva, Julia Borges Paes Lemes, Gabriela Geronimo, Fernando Freitas de Lima, Ludmilla David de Moura, Ariany Carvalho Dos Santos, Nathalia Santos Carvalho, Kauê Franco Malange, Márcia C Breitkreitz, Carlos A Parada, Eneida de Paula. Lipid nanoparticles loaded with butamben and designed to improve anesthesia at inflamed tissues. Biomaterials science. 2021 May; 9(9):3378-3389. doi: 10.1039/d1bm00077b. [PMID: 33949447]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Renata A Grothe, Alnilan Lobato, Bassim Mounssef, Nikola Tasić, Ataualpa A C Braga, Adriano O Maldaner, Leigh Aldous, Thiago R L C Paixão, Luís Moreira Gonçalves. Electroanalytical profiling of cocaine samples by means of an electropolymerized molecularly imprinted polymer using benzocaine as the template molecule. The Analyst. 2021 Mar; 146(5):1747-1759. doi: 10.1039/d0an02274h. [PMID: 33470260]
  • Bo Dou, Wenji Hu, Minkai Song, Robert J Lee, Xiaoyu Zhang, Di Wang. Anti-inflammation of Erianin in dextran sulphate sodium-induced ulcerative colitis mice model via collaborative regulation of TLR4 and STAT3. Chemico-biological interactions. 2020 Jun; 324(?):109089. doi: 10.1016/j.cbi.2020.109089. [PMID: 32272095]
  • Hsiao-Mei Huang, Man-Hui Pai, Sung-Ling Yeh, Yu-Chen Hou. Dietary exposure to chlorpyrifos inhibits the polarization of regulatory T cells in C57BL/6 mice with dextran sulfate sodium-induced colitis. Archives of toxicology. 2020 01; 94(1):141-150. doi: 10.1007/s00204-019-02615-2. [PMID: 31807802]
  • Lorretta E Uche, Gerrit S Gooris, Joke A Bouwstra, Charlotte M Beddoes. Barrier Capability of Skin Lipid Models: Effect of Ceramides and Free Fatty Acid Composition. Langmuir : the ACS journal of surfaces and colloids. 2019 11; 35(47):15376-15388. doi: 10.1021/acs.langmuir.9b03029. [PMID: 31698908]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Colleen E Thurman, Skye Rasmussen, Kevin A Prestia. Effect of 3 Euthanasia Methods on Serum Yield and Serum Cortisol Concentration in Zebrafish (Danio rerio). Journal of the American Association for Laboratory Animal Science : JAALAS. 2019 11; 58(6):823-828. doi: 10.30802/aalas-jaalas-18-000144. [PMID: 31662156]
  • Hsiao-Mei Huang, Man-Hui Pai, Jun-Jen Liu, Sung-Ling Yeh, Yu-Chen Hou. Effects of dietary exposure to chlorpyrifos on immune cell populations and inflammatory responses in mice with dextran sulfate sodium-induced colitis. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2019 Sep; 131(?):110596. doi: 10.1016/j.fct.2019.110596. [PMID: 31226429]
  • Yuti Yin, Lei Ye, Zhongbao Niu, Wenhui Fang. Anti-inflammatory effects of Vicenin-2 on dextran sulfate sodium-induced colitis in mice. Drug development research. 2019 08; 80(5):546-555. doi: 10.1002/ddr.21529. [PMID: 30972795]
  • Mohita Sharma, Ramanpreet Kaur, Kuldeep Kaushik, Naveen Kaushal. Redox modulatory protective effects of ω-3 fatty acids rich fish oil against experimental colitis. Toxicology mechanisms and methods. 2019 May; 29(4):244-254. doi: 10.1080/15376516.2018.1553220. [PMID: 30489199]
  • Hai-Tao Xiao, Jiao Peng, Bo Wen, Dong-Dong Hu, Xiao-Peng Hu, Xiang-Chun Shen, Zhi-Gang Liu, Zhen-Dan He, Zhao-Xiang Bian. Indigo Naturalis Suppresses Colonic Oxidative Stress and Th1/Th17 Responses of DSS-Induced Colitis in Mice. Oxidative medicine and cellular longevity. 2019; 2019(?):9480945. doi: 10.1155/2019/9480945. [PMID: 31737179]
  • Natascha Wosnick, Fabiano Bendhack, Renata D Leite, Rosana N Morais, Carolina A Freire. Benzocaine-induced stress in the euryhaline teleost, Centropomus parallelus and its implications for anesthesia protocols. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 2018 12; 226(?):32-37. doi: 10.1016/j.cbpa.2018.07.021. [PMID: 30056161]
  • Chaundra R Sewell, Michael P Rivey. A Case Report of Benzocaine-Induced Methemoglobinemia. Journal of pharmacy practice. 2018 Oct; 31(5):507-509. doi: 10.1177/0897190017723211. [PMID: 28803519]
  • Chenchen Ding, Wentao Fan, Tongtong Shen, Kehe Huang, Suquan Song, Liping Yan. Zearalenone can relieve dextran sulfate sodium-induced inflammatory reaction. Journal of biochemical and molecular toxicology. 2018 Oct; ?(?):e22236. doi: 10.1002/jbt.22236. [PMID: 30270565]
  • Ksenia Aaron, Tess E Cooper, Laura Warner, Martin J Burton. Ear drops for the removal of ear wax. The Cochrane database of systematic reviews. 2018 07; 7(?):CD012171. doi: 10.1002/14651858.cd012171.pub2. [PMID: 30043448]
  • Briony D Smith, Krystal J Vail, Gwendolyn L Carroll, Maggie C Taylor, Nicholas D Jeffery, Tracy H Vemulapalli, James J Elliott. Comparison of Etomidate, Benzocaine, and MS222 Anesthesia with and without Subsequent Flunixin Meglumine Analgesia in African Clawed Frogs (Xenopus laevis). Journal of the American Association for Laboratory Animal Science : JAALAS. 2018 03; 57(2):202-209. doi: NULL. [PMID: 29555009]
  • G Mangiapia, M Gvaramia, L Kuhrts, J Teixeira, A Koutsioubas, O Soltwedel, H Frielinghaus. Effect of benzocaine and propranolol on phospholipid-based bilayers. Physical chemistry chemical physics : PCCP. 2017 Dec; 19(47):32057-32071. doi: 10.1039/c7cp06077g. [PMID: 29181470]
  • Shoichiro Kawai, Hideki Iijima, Shinichiro Shinzaki, Satoshi Hiyama, Toshio Yamaguchi, Manabu Araki, Shuko Iwatani, Eri Shiraishi, Akira Mukai, Takahiro Inoue, Yoshito Hayashi, Masahiko Tsujii, Daisuke Motooka, Shota Nakamura, Tetsuya Iida, Tetsuo Takehara. Indigo Naturalis ameliorates murine dextran sodium sulfate-induced colitis via aryl hydrocarbon receptor activation. Journal of gastroenterology. 2017 Aug; 52(8):904-919. doi: 10.1007/s00535-016-1292-z. [PMID: 27900483]
  • Nan Hu, Yanjuan Huang, Xuejiao Gao, Sai Li, Zhixiang Yan, Bin Wei, Ru Yan. Effects of dextran sulfate sodium induced experimental colitis on cytochrome P450 activities in rat liver, kidney and intestine. Chemico-biological interactions. 2017 Jun; 271(?):48-58. doi: 10.1016/j.cbi.2017.04.018. [PMID: 28438436]
  • Sisi Lin, Yongyu Li, Li Shen, Ruiqin Zhang, Lizhi Yang, Min Li, Kun Li, Jakub Fichna. The Anti-Inflammatory Effect and Intestinal Barrier Protection of HU210 Differentially Depend on TLR4 Signaling in Dextran Sulfate Sodium-Induced Murine Colitis. Digestive diseases and sciences. 2017 02; 62(2):372-386. doi: 10.1007/s10620-016-4404-y. [PMID: 27995407]
  • Giovanna R Stringhetta, Luis A L Barbas, Lucas C Maltez, Luís A Sampaio, José M Monserrat, Luciano O Garcia. Oxidative stress responses of juvenile tambaqui Colossoma macropomum after short-term anesthesia with benzocaine and MS-222. Anais da Academia Brasileira de Ciencias. 2017; 89(3 Suppl):2209-2218. doi: 10.1590/0001-3765201720160823. [PMID: 28746612]
  • Ya-Jing Feng, Yong-Yu Li, Xu-Hong Lin, Kun Li, Ming-Hua Cao. Anti-inflammatory effect of cannabinoid agonist WIN55, 212 on mouse experimental colitis is related to inhibition of p38MAPK. World journal of gastroenterology. 2016 Nov; 22(43):9515-9524. doi: 10.3748/wjg.v22.i43.9515. [PMID: 27920472]
  • Monika Rau, Bruno Stieger, Maria J Monte, Johannes Schmitt, Daniel Jahn, Isabelle Frey-Wagner, Tina Raselli, Jose J G Marin, Beat Müllhaupt, Gerhard Rogler, Andreas Geier. Alterations in Enterohepatic Fgf15 Signaling and Changes in Bile Acid Composition Depend on Localization of Murine Intestinal Inflammation. Inflammatory bowel diseases. 2016 10; 22(10):2382-9. doi: 10.1097/mib.0000000000000879. [PMID: 27580383]
  • Sahil Somani, Shitalkumar Zambad, Ketan Modi. Mangiferin attenuates DSS colitis in mice: Molecular docking and in vivo approach. Chemico-biological interactions. 2016 Jun; 253(?):18-26. doi: 10.1016/j.cbi.2016.04.033. [PMID: 27125760]
  • Kanakaraju Medicherla, Bidya Dhar Sahu, Madhusudana Kuncha, Jerald Mahesh Kumar, Godi Sudhakar, Ramakrishna Sistla. Oral administration of geraniol ameliorates acute experimental murine colitis by inhibiting pro-inflammatory cytokines and NF-κB signaling. Food & function. 2015 Sep; 6(9):2984-95. doi: 10.1039/c5fo00405e. [PMID: 26190278]
  • Jun Yao, Cheng Wei, Jian-Yao Wang, Ru Zhang, Ying-Xue Li, Li-Sheng Wang. Effect of resveratrol on Treg/Th17 signaling and ulcerative colitis treatment in mice. World journal of gastroenterology. 2015 Jun; 21(21):6572-81. doi: 10.3748/wjg.v21.i21.6572. [PMID: 26074695]
  • Yanjuan Huang, Nan Hu, Xuejiao Gao, Zhixiang Yan, Sai Li, Wanghui Jing, Ru Yan. Alterations of testosterone metabolism in microsomes from rats with experimental colitis induced by dextran sulfate sodium. Chemico-biological interactions. 2015 May; 232(?):38-48. doi: 10.1016/j.cbi.2015.02.013. [PMID: 25777935]
  • Jingjing Zhang, Lili Ding, Baocan Wang, Gaiyan Ren, Aning Sun, Chao Deng, Xiaohui Wei, Sridhar Mani, Zhengtao Wang, Wei Dou. Notoginsenoside R1 attenuates experimental inflammatory bowel disease via pregnane X receptor activation. The Journal of pharmacology and experimental therapeutics. 2015 Feb; 352(2):315-24. doi: 10.1124/jpet.114.218750. [PMID: 25472953]
  • Hui Sun, Jia-Ping Lai, Fang Chen, De-Rong Zhu. Molecularly imprinted microspheres synthesized by a simple, fast, and universal suspension polymerization for selective extraction of the topical anesthetic benzocaine in human serum and fish tissues. Analytical and bioanalytical chemistry. 2015 Feb; 407(6):1745-52. doi: 10.1007/s00216-014-8420-5. [PMID: 25577355]
  • Kyung-Sook Chung, Hye-Eun Choi, Ji-Sun Shin, Eu-Jin Cho, Young-Wuk Cho, Jung-Hye Choi, Nam-In Baek, Kyung-Tae Lee. Chemopreventive effects of standardized ethanol extract from the aerial parts of Artemisia princeps Pampanini cv. Sajabal via NF-κB inactivation on colitis-associated colon tumorigenesis in mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2015 Jan; 75(?):14-23. doi: 10.1016/j.fct.2014.11.007. [PMID: 25449198]
  • Mona Basha, Sameh Hosam Abd El-Alim, Ahmed Alaa Kassem, Sally El Awdan, Gamal Awad. Benzocaine loaded solid lipid nanoparticles: Formulation design, in vitro and in vivo evaluation of local anesthetic effect. Current drug delivery. 2015; 12(6):680-92. doi: 10.2174/1567201812666150703115126. [PMID: 26138680]
  • S Samo, M Parikh, J Sheth, S Krishnan, V Ganipisetti. Treatment of methemoglobinemia resulting in green urine. QJM : monthly journal of the Association of Physicians. 2014 Dec; 107(12):1039. doi: 10.1093/qjmed/hcu085. [PMID: 24729267]
  • Markéta Paloncýová, Russell H DeVane, Bruce P Murch, Karel Berka, Michal Otyepka. Rationalization of reduced penetration of drugs through ceramide gel phase membrane. Langmuir : the ACS journal of surfaces and colloids. 2014 Nov; 30(46):13942-8. doi: 10.1021/la503289v. [PMID: 25354090]
  • H A Spiller, J L Russell, M J Casavant, R Y Ho, R R Gerona. Identification of N-Hydroxy-para-aminobenzoic acid in a cyanotic child after benzocaine exposure. Clinical toxicology (Philadelphia, Pa.). 2014 Nov; 52(9):976-9. doi: 10.3109/15563650.2014.958615. [PMID: 25211007]
  • Naveen Kaushal, Avinash K Kudva, Andrew D Patterson, Christopher Chiaro, Mary J Kennett, Dhimant Desai, Shantu Amin, Bradley A Carlson, Margherita T Cantorna, K Sandeep Prabhu. Crucial role of macrophage selenoproteins in experimental colitis. Journal of immunology (Baltimore, Md. : 1950). 2014 Oct; 193(7):3683-92. doi: 10.4049/jimmunol.1400347. [PMID: 25187657]
  • Céline Boiteux, Igor Vorobyov, Robert J French, Christopher French, Vladimir Yarov-Yarovoy, Toby W Allen. Local anesthetic and antiepileptic drug access and binding to a bacterial voltage-gated sodium channel. Proceedings of the National Academy of Sciences of the United States of America. 2014 Sep; 111(36):13057-62. doi: 10.1073/pnas.1408710111. [PMID: 25136136]
  • Lewis J Martin, Ben Corry. Locating the route of entry and binding sites of benzocaine and phenytoin in a bacterial voltage gated sodium channel. PLoS computational biology. 2014 Jul; 10(7):e1003688. doi: 10.1371/journal.pcbi.1003688. [PMID: 24992293]
  • Mohamed E Shaker, Sylvia A Ashamallah, Maha E Houssen. Celastrol ameliorates murine colitis via modulating oxidative stress, inflammatory cytokines and intestinal homeostasis. Chemico-biological interactions. 2014 Mar; 210(?):26-33. doi: 10.1016/j.cbi.2013.12.007. [PMID: 24384223]
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  • Lewis J Martin, Rebecca Chao, Ben Corry. Molecular dynamics simulation of the partitioning of benzocaine and phenytoin into a lipid bilayer. Biophysical chemistry. 2014 Jan; 185(?):98-107. doi: 10.1016/j.bpc.2013.12.003. [PMID: 24406394]
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  • Georgette Oni, Yvonne Rasko, Jeffrey Kenkel. Topical lidocaine enhanced by laser pretreatment: a safe and effective method of analgesia for facial rejuvenation. Aesthetic surgery journal. 2013 Aug; 33(6):854-61. doi: 10.1177/1090820x13496248. [PMID: 23908302]
  • Ji-Sun Shin, Kyung-Jin Yun, Kyung-Sook Chung, Kyeong-Hwa Seo, Hee-Juhn Park, Young-Wuk Cho, Nam-In Baek, Daesik Jang, Kyung-Tae Lee. Monotropein isolated from the roots of Morinda officinalis ameliorates proinflammatory mediators in RAW 264.7 macrophages and dextran sulfate sodium (DSS)-induced colitis via NF-κB inactivation. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2013 Mar; 53(?):263-71. doi: 10.1016/j.fct.2012.12.013. [PMID: 23261679]
  • J J López Cascales, S D Oliveira Costa. Effect of the interfacial tension and ionic strength on the thermodynamic barrier associated to the benzocaine insertion into a cell membrane. Biophysical chemistry. 2013 Feb; 172(?):1-7. doi: 10.1016/j.bpc.2012.12.001. [PMID: 23333594]
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  • Javier Rivera Guzman, Ja Seol Koo, Jason R Goldsmith, Marcus Mühlbauer, Acharan Narula, Christian Jobin. Oxymatrine prevents NF-κB nuclear translocation and ameliorates acute intestinal inflammation. Scientific reports. 2013; 3(?):1629. doi: 10.1038/srep01629. [PMID: 23568217]
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