Mupirocin (BioDeep_00000398797)

Main id: BioDeep_00000003883

 

natural product Chemicals and Drugs Antibiotics


代谢物信息卡片


Mupirocin

化学式: C26H44O9 (500.29851740000004)
中文名称: 莫匹罗星
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C/C(=C\C(=O)OCCCCCCCCC(=O)O)/C[C@H]1[C@@H]([C@@H]([C@@H](C[C@H]2[C@H]([C@@H](C)[C@H](C)O)O2)CO1)O)O
InChI: InChI=1S/C26H44O9/c1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27/h13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29)/b16-13+/t17-,18-,19-,20-,21-,24+,25-,26-/m0/s1

描述信息

An alpha,beta-unsaturated ester resulting from the formal condensation of the alcoholic hydroxy group of 9-hydroxynonanoic acid with the carboxy group of (2E)-4-[(2S)-tetrahydro-2H-pyran-2-yl]-3-methylbut-2-enoic acid in which the tetrahydropyranyl ring is substituted at positions 3 and 4 by hydroxy groups and at position 5 by a {(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl}methyl group. Originally isolated from the Gram-negative bacterium Pseudomonas fluorescens, it is used as a topical antibiotic for the treatment of Gram-positive bacterial infections.
D - Dermatologicals > D06 - Antibiotics and chemotherapeutics for dermatological use > D06A - Antibiotics for topical use
R - Respiratory system > R01 - Nasal preparations > R01A - Decongestants and other nasal preparations for topical use
D004791 - Enzyme Inhibitors > D011500 - Protein Synthesis Inhibitors
C254 - Anti-Infective Agent > C28394 - Topical Anti-Infective Agent
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
Mupirocin (BRL-4910A, Pseudomonic acid) is an orally active antibiotic isolated from Pseudomonas fluorescens. Mupirocin apparently exerts its antimicrobial activity by reversibly inhibiting isoleucyl-transfer RNA, thereby inhibiting bacterial protein and RNA synthesis[1][2].

同义名列表

3 个代谢物同义名

Mupirocin; BRL-4910A; Pseudomonic acid



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Yaya Qiao, Meng Su, Huifang Zhao, Huanle Liu, Chenxi Wang, Xintong Dai, Lingling Liu, Guangju Liu, Huanran Sun, Mingming Sun, Jiyan Wang, Zhen Li, Jun Fan, Quan Zhang, Chunshen Li, Fangmin Situ, Jun Xue, Zhenghu Jia, Chunze Zhang, Shuai Zhang, Changliang Shan. Targeting FTO induces colorectal cancer ferroptotic cell death by decreasing SLC7A11/GPX4 expression. Journal of experimental & clinical cancer research : CR. 2024 Apr; 43(1):108. doi: 10.1186/s13046-024-03032-9. [PMID: 38600610]
  • Hai Bang Pan, Yan Cui, Zhi Hang Wu, Ying Meng, Tian Ming Wang, Qi Fu, Qian Chen, Quan Xin Chen, Bo Wang. Effect of Different Local Antibiotic Regimens on Prevention of Postoperative Infection in Clean Surgical Wounds: A Systematic Review and Network Meta-analysis. Advances in skin & wound care. 2024 Apr; 37(4):216-223. doi: 10.1097/asw.0000000000000094. [PMID: 38353666]
  • Priyanka V Patil, Mala D Menon, Aparna D Palshetkar, Namita D Desai. Topical delivery of mupirocin calcium nanostructured lipid carriers using a full-thickness excision wound healing model. Journal of wound care. 2023 May; 32(Sup5a):lxiii-lxxiv. doi: 10.12968/jowc.2023.32.sup5a.lxiii. [PMID: 37094978]
  • Lila Moghiseh, Monir Nobahar, Raheb Ghorbani, Shiva Sirafian. The impact of Propolis on catheter exit site infection and peritonitis in peritoneal Dialysis patients: a clinical trial. BMC nephrology. 2022 12; 23(1):408. doi: 10.1186/s12882-022-03036-7. [PMID: 36564743]
  • Zhiling Cai, Zitong Mo, Shiqian Zheng, Shihua Lan, Shengjun Xie, Jinghui Lu, Chunping Tang, Zhibin Shen. Flavaspidic acid BB combined with mupirocin improves its anti-bacterial and anti-biofilm activities against Staphylococcus epidermidis. BMC microbiology. 2022 07; 22(1):179. doi: 10.1186/s12866-022-02578-y. [PMID: 35840879]
  • Nannan Zhang, Jin Wu, Siping Zhang, Maoran Yuan, Hang Xu, Jie Li, Pingping Zhang, Mingzhu Wang, Megan L Kempher, Xuanyu Tao, Li-Qun Zhang, Honghua Ge, Yong-Xing He. Molecular basis for coordinating secondary metabolite production by bacterial and plant signaling molecules. The Journal of biological chemistry. 2022 06; 298(6):102027. doi: 10.1016/j.jbc.2022.102027. [PMID: 35568198]
  • George A Naclerio, Nader S Abutaleb, Kenneth I Onyedibe, Caroline Karanja, Hassan E Eldesouky, Hsin-Wen Liang, Alexandra Dieterly, Uma K Aryal, Tiffany Lyle, Mohamed N Seleem, Herman O Sintim. Mechanistic Studies and In Vivo Efficacy of an Oxadiazole-Containing Antibiotic. Journal of medicinal chemistry. 2022 05; 65(9):6612-6630. doi: 10.1021/acs.jmedchem.1c02034. [PMID: 35482444]
  • Mansi Budhiraja, Sobiya Zafar, Sohail Akhter, Majed Alrobaian, Md Abdur Rashid, Md Abul Barkat, Sarwar Beg, Farhan J Ahmad. Mupirocin-Loaded Chitosan Microspheres Embedded in Piper betle Extract Containing Collagen Scaffold Accelerate Wound Healing Activity. AAPS PharmSciTech. 2022 Feb; 23(3):77. doi: 10.1208/s12249-022-02233-9. [PMID: 35194725]
  • Zeynep Ay Şenyiğit, Nesrin Coşkunmeriç, Emre Şefik Çağlar, İsmail Öztürk, Evren Atlıhan Gündoğdu, Panoraia I Siafaka, Neslihan Üstündağ Okur. Chitosan-bovine serum albumin-Carbopol 940 nanogels for mupirocin dermal delivery: ex-vivo permeation and evaluation of cellular binding capacity via radiolabeling. Pharmaceutical development and technology. 2021 Oct; 26(8):852-866. doi: 10.1080/10837450.2021.1948570. [PMID: 34193003]
  • Haroon Mohammad, Nader S Abutaleb, Alexandra M Dieterly, L Tiffany Lyle, Mohamed N Seleem. Investigating auranofin for the treatment of infected diabetic pressure ulcers in mice and dermal toxicity in pigs. Scientific reports. 2021 05; 11(1):10935. doi: 10.1038/s41598-021-90360-x. [PMID: 34035383]
  • Alok Pratap Singh, Satish Kumar Sharma, Praveen Kumar Gaur, Dinesh Kumar Gupta. Fabrication of Mupirocin-Loaded Nanostructured Lipid Carrier and Its In Vitro Characterization. Assay and drug development technologies. 2021 May; 19(4):216-225. doi: 10.1089/adt.2020.1070. [PMID: 33781090]
  • Victoria S Lee, Paul S Pottinger, Greg E Davis. Tolerability and effectiveness of povidone-iodine or mupirocin versus saline sinus irrigations for chronic rhinosinusitis. American journal of otolaryngology. 2020 Sep; 41(5):102604. doi: 10.1016/j.amjoto.2020.102604. [PMID: 32563787]
  • Morteza Najaf Zadeh Gharaboghaz, Mohammad Reza Farahpour, Shahram Saghaie. Topical co-administration of Teucrium polium hydroethanolic extract and Aloe vera gel triggered wound healing by accelerating cell proliferation in diabetic mouse model. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2020 Jul; 127(?):110189. doi: 10.1016/j.biopha.2020.110189. [PMID: 32388242]
  • George A Yendewa, J McLeod Griffiss, Michael R Jacobs, Scott A Fulton, Mary Ann O'Riordan, Wesley A Gray, Howard M Proskin, Peter Winkle, Robert A Salata. A two-part phase 1 study to establish and compare the safety and local tolerability of two nasal formulations of XF-73 for decolonisation of Staphylococcus aureus: A previously investigated 0.5mg/g viscosified gel formulation versus a modified formulation. Journal of global antimicrobial resistance. 2020 06; 21(?):171-180. doi: 10.1016/j.jgar.2019.09.017. [PMID: 31600598]
  • Aisha Zia, Marium Hasan, Sidra Ilyas, Hafiz Umair Siddiqui, Bassman Tappuni, Shayan Marsia, M Mujeeb Zubair, Sajjad Raza, Rami R Mustafa, Zulfiqar Qutrio Baloch, Salil V Deo, Umesh M Sharma, Mohammad Adil Sheikh. Reining in Sternal Wound Infections: The Achilles' Heel of Bilateral Internal Thoracic Artery Grafting. Surgical infections. 2020 May; 21(4):323-331. doi: 10.1089/sur.2018.142. [PMID: 31829828]
  • Dong Heun Lee, Gregory Malat, Suzanne M Boyle, Sindhura Talluri, Tiffany E Bias, Meera N Harhay, Karthik Ranganna, Alden Doyle. Safety and Efficacy of Universal Postoperative Decolonization for Kidney Transplant Recipients. Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation. 2020 04; 18(2):153-156. doi: 10.6002/ect.2018.0341. [PMID: 31266440]
  • Natalia Pettinelli, Saddys Rodríguez-Llamazares, Yousof Farrag, Rebeca Bouza, Luis Barral, Sandra Feijoo-Bandín, Francisca Lago. Poly(hydroxybutyrate-co-hydroxyvalerate) microparticles embedded in κ-carrageenan/locust bean gum hydrogel as a dual drug delivery carrier. International journal of biological macromolecules. 2020 Mar; 146(?):110-118. doi: 10.1016/j.ijbiomac.2019.12.193. [PMID: 31881300]
  • Oliver Goldmann, Ahuva Cern, Mathias Müsken, Manfred Rohde, William Weiss, Yechezkel Barenholz, Eva Medina. Liposomal mupirocin holds promise for systemic treatment of invasive Staphylococcus aureus infections. Journal of controlled release : official journal of the Controlled Release Society. 2019 12; 316(?):292-301. doi: 10.1016/j.jconrel.2019.11.007. [PMID: 31715276]
  • Surapon Nochaiwong, Chidchanok Ruengorn, Kajohnsak Noppakun, Setthapon Panyathong, Phongsak Dandecha, Manish M Sood, Chalermpong Saenjum, Ratanaporn Awiphan, Sasithorn Sirilun, Pajaree Mongkhon, Wilaiwan Chongruksut, Kednapa Thavorn. Comparative Effectiveness of Local Application of Chlorhexidine Gluconate, Mupirocin Ointment, and Normal Saline for the Prevention of Peritoneal Dialysis-related Infections (COSMO-PD Trial): a multicenter randomized, double-blind, controlled protocol. Trials. 2019 Dec; 20(1):754. doi: 10.1186/s13063-019-3953-8. [PMID: 31856900]
  • Khent P Alcantara, Mohd Hanif Zulfakar, Agnes L Castillo. Development, characterization and pharmacokinetics of mupirocin-loaded nanostructured lipid carriers (NLCs) for intravascular administration. International journal of pharmaceutics. 2019 Nov; 571(?):118705. doi: 10.1016/j.ijpharm.2019.118705. [PMID: 31536765]
  • Charlotta Magnusson, Marc Stegger, Bengt Hellmark, Bianca Stenmark, Bo Söderquist. Staphylococcus aureus isolates from nares of orthopaedic patients in Sweden are mupirocin susceptible. Infectious diseases (London, England). 2019 06; 51(6):475-478. doi: 10.1080/23744235.2019.1593500. [PMID: 30985251]
  • Oleg N Reva, Sunelle Rademan, Michelle H Visagie, Maphuti T Lebelo, Mokgadi V Gwangwa, Vitalii V Klochko, Anna M Joubert, Namrita Lall. Comparison of structures and cytotoxicity of mupirocin and batumin against melanoma and several other cancer cell lines. Future medicinal chemistry. 2019 04; 11(7):677-691. doi: 10.4155/fmc-2018-0333. [PMID: 30947530]
  • Xiaofang Lv, Rui Feng, Jingbo Zhai. A combination of mupirocin and acidic fibroblast growth factor for nipple fissure and nipple pain in breastfeeding women: protocol for a randomised, double-blind, controlled trial. BMJ open. 2019 03; 9(3):e025526. doi: 10.1136/bmjopen-2018-025526. [PMID: 30918032]
  • Theo O Dare, Andrew W Nicholls, Peter G Mantle. Monic acid A: a biomarker in clinical intra-nasal mupirocin medication for MRSA decolonisation. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 2019 Mar; 24(2):131-133. doi: 10.1080/1354750x.2018.1514657. [PMID: 30126316]
  • Johannes Arp, Sebastian Götze, Ruchira Mukherji, Derek J Mattern, María García-Altares, Martin Klapper, Debra A Brock, Axel A Brakhage, Joan E Strassmann, David C Queller, Bettina Bardl, Karsten Willing, Gundela Peschel, Pierre Stallforth. Synergistic activity of cosecreted natural products from amoebae-associated bacteria. Proceedings of the National Academy of Sciences of the United States of America. 2018 04; 115(15):3758-3763. doi: 10.1073/pnas.1721790115. [PMID: 29592954]
  • Jian Huang, Jinhua Huang, Yaping Xiang, Lihua Gao, Yizhi Pan, Jianyun Lu. [Topical ozone therapy: An innovative solution to patients with herpes zoster]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. 2018 Feb; 43(2):168-172. doi: 10.11817/j.issn.1672-7347.2018.02.011. [PMID: 29559601]
  • Kordo Saeed, Ian Gould, Silvano Esposito, Nusreen Ahmad-Saeed, Salman Shaheer Ahmed, Emine Alp, Abhijit M Bal, Matteo Bassetti, Eric Bonnet, Monica Chan, Geoffrey Coombs, Stephanie J Dancer, Michael Z David, Giuseppe De Simone, Matthew Dryden, Luca Guardabassi, Leif G Hanitsch, Karolin Hijazi, Renate Krüger, Andie Lee, Rasmus Leistner, Pasquale Pagliano, Elda Righi, Sylke Schneider-Burrus, Robert Leo Skov, Pierre Tattevin, Willem Van Wamel, Margreet C Vos, Andreas Voss. Panton-Valentine leukocidin-positive Staphylococcus aureus: a position statement from the International Society of Chemotherapy. International journal of antimicrobial agents. 2018 Jan; 51(1):16-25. doi: 10.1016/j.ijantimicag.2017.11.002. [PMID: 29174420]
  • Aleksandra Budzyńska, Sylwia Różalska, Beata Sadowska, Barbara Różalska. Candida albicans/Staphylococcus aureus Dual-Species Biofilm as a Target for the Combination of Essential Oils and Fluconazole or Mupirocin. Mycopathologia. 2017 Dec; 182(11-12):989-995. doi: 10.1007/s11046-017-0192-y. [PMID: 28823093]
  • Lei Zhang, Sunil V Badve, Elaine M Pascoe, Elaine Beller, Alan Cass, Carolyn Clark, Janak de Zoysa, Nicole M Isbel, Xusheng Liu, Steven McTaggart, Alicia T Morrish, Geoffrey Playford, Anish Scaria, Paul Snelling, Liza A Vergara, Carmel M Hawley, David W Johnson. Representativeness of Honeypot Trial Participants to Australasian PD Patients. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. 2017 Sep; 37(5):516-522. doi: 10.3747/pdi.2016.00065. [PMID: 27935534]
  • Xiaowen Su, Xinguang Liu, Shouyu Wang, Bin Li, Taowen Pan, Dingrui Liu, Fei Wang, Yunpeng Diao, Kun Li. Wound-healing promoting effect of total tannins from Entada phaseoloides (L.) Merr. in rats. Burns : journal of the International Society for Burn Injuries. 2017 Jun; 43(4):830-838. doi: 10.1016/j.burns.2016.10.010. [PMID: 28040363]
  • Htay Htay, David W Johnson, Sin Yan Wu, Elizabeth Ley Oei, Marjorie Wai Yin Foo, Jason Chon Jun Choo. Comparison of Topical Chlorhexidine and Mupirocin for the Prevention of Exit-Site Infection in Incident Peritoneal Dialysis Patients. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. 2017 May; 37(3):266-272. doi: 10.3747/pdi.2016.00257. [PMID: 28183858]
  • Martin Wilkie. Improving the Impact of Peritoneal Dialysis Research. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. 2017 May; 37(3):245-246. doi: 10.3747/pdi.2017.00001. [PMID: 28512160]
  • Denise Campbell, David W Mudge, Jonathan C Craig, David W Johnson, Allison Tong, Giovanni Fm Strippoli. Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients. The Cochrane database of systematic reviews. 2017 04; 4(?):CD004679. doi: 10.1002/14651858.cd004679.pub3. [PMID: 28390069]
  • Ping-Nam Wong, Gensy M W Tong, Yuk-Yi Wong, Kin-Yee Lo, Shuk-Fan Chan, Man-Wai Lo, Kwok-Chi Lo, Lo-Yi Ho, Cindy W S Tse, Siu-Ka Mak, Andrew K M Wong. Alternating Mupirocin/Gentamicin is Associated with Increased Risk of Fungal Peritonitis as Compared with Gentamicin Alone - Results of a Randomized Open-Label Controlled Trial. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. 2016 May; 36(3):340-6. doi: 10.3747/pdi.2015.00237. [PMID: 27044796]
  • J Novakova, E Vlkova, H Salmonova, R Pechar, V Rada, L Kokoska. Anticlostridial agent 8-hydroxyquinoline improves the isolation of faecal bifidobacteria on modified Wilkins-Chalgren agar with mupirocin. Letters in applied microbiology. 2016 Apr; 62(4):330-5. doi: 10.1111/lam.12552. [PMID: 26849418]
  • Shigeki Toma, Takahiro Shinzato, Kunihiro Hayakawa. Access-Related Infections Involving the Buttonhole Technique. Blood purification. 2016; 41(4):306-12. doi: 10.1159/000443781. [PMID: 26820709]
  • Susan S Huang, Edward Septimus, Mary K Hayden, Ken Kleinman, Jessica Sturtevant, Taliser R Avery, Julia Moody, Jason Hickok, Julie Lankiewicz, Adrijana Gombosev, Rebecca E Kaganov, Katherine Haffenreffer, John A Jernigan, Jonathan B Perlin, Richard Platt, Robert A Weinstein. Effect of body surface decolonisation on bacteriuria and candiduria in intensive care units: an analysis of a cluster-randomised trial. The Lancet. Infectious diseases. 2016 Jan; 16(1):70-79. doi: 10.1016/s1473-3099(15)00238-8. [PMID: 26631833]
  • S Murugesan, U Singh, N Perumal, V Ramanathan, P Krishnan. High level mupirocin resistance among CoNS from nasal carriers of End stage renal disease patients and hospital personnel from tertiary care centre, Chennai. Indian journal of medical microbiology. 2016 Jan; 34(1):114-5. doi: 10.4103/0255-0857.167672. [PMID: 26776137]
  • Lei Zhang, Sunil V Badve, Elaine M Pascoe, Elaine Beller, Alan Cass, Carolyn Clark, Janak de Zoysa, Nicole M Isbel, Steven McTaggart, Alicia T Morrish, E Geoffrey Playford, Anish Scaria, Paul Snelling, Liza A Vergara, Carmel M Hawley, David W Johnson. The Effect of Exit-Site Antibacterial Honey Versus Nasal Mupirocin Prophylaxis on the Microbiology and Outcomes of Peritoneal Dialysis-Associated Peritonitis and Exit-Site Infections: A Sub-Study of the Honeypot Trial. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. 2015 Dec; 35(7):712-21. doi: 10.3747/pdi.2014.00206. [PMID: 26224790]
  • Bryce D Beutler, Philip R Cohen. Verruciform Genital-Associated (Vegas) Xanthoma: report of a patient with verruciform xanthoma of the scrotum and literature review. Dermatology online journal. 2015 Aug; 21(8):. doi: ". [PMID: 26437158]
  • Qingzhong Liu, Huanqiang Zhao, Lizhong Han, Wen Shu, Qiong Wu, Yuxing Ni. Frequency of biocide-resistant genes and susceptibility to chlorhexidine in high-level mupirocin-resistant, methicillin-resistant Staphylococcus aureus (MuH MRSA). Diagnostic microbiology and infectious disease. 2015 Aug; 82(4):278-83. doi: 10.1016/j.diagmicrobio.2015.03.023. [PMID: 26008124]
  • Arnav Agarwal, Gihad Nesrallah. Long-Term Safety of Buttonhole Cannulation and Efficacy of Mupirocin Prophylaxis. Contributions to nephrology. 2015; 186(?):64-70. doi: 10.1159/000431162. [PMID: 26283561]
  • Cibele Grothe, Mônica Taminato, Angélica Belasco, Ricardo Sesso, Dulce Barbosa. Screening and treatment for Staphylococcus aureus in patients undergoing hemodialysis: a systematic review and meta-analysis. BMC nephrology. 2014 Dec; 15(?):202. doi: 10.1186/1471-2369-15-202. [PMID: 25519998]
  • Radko Pechar, Vojtech Rada, Lucia Parafati, Sarka Musilova, Vera Bunesova, Eva Vlkova, Jiri Killer, Jakub Mrazek, Vladimir Kmet, Roman Svejstil. Mupirocin-mucin agar for selective enumeration of Bifidobacterium bifidum. International journal of food microbiology. 2014 Nov; 191(?):32-5. doi: 10.1016/j.ijfoodmicro.2014.08.032. [PMID: 25217723]
  • Laura M Thoma, Blaise R Boles, Kenichi Kuroda. Cationic methacrylate polymers as topical antimicrobial agents against Staphylococcus aureus nasal colonization. Biomacromolecules. 2014 Aug; 15(8):2933-43. doi: 10.1021/bm500557d. [PMID: 25010735]
  • Ahuva Cern, Einat Nativ-Roth, Amiram Goldblum, Yechezkel Barenholz. Effect of solubilizing agents on mupirocin loading into and release from PEGylated nanoliposomes. Journal of pharmaceutical sciences. 2014 Jul; 103(7):2131-2138. doi: 10.1002/jps.24037. [PMID: 24898012]
  • Thangavelu Muthukumar, P Prabu, Kausik Ghosh, Thotapalli Parvathaleswara Sastry. Fish scale collagen sponge incorporated with Macrotyloma uniflorum plant extract as a possible wound/burn dressing material. Colloids and surfaces. B, Biointerfaces. 2014 Jan; 113(?):207-12. doi: 10.1016/j.colsurfb.2013.09.019. [PMID: 24096157]
  • David W Johnson, Sunil V Badve, Elaine M Pascoe, Elaine Beller, Alan Cass, Carolyn Clark, Janak de Zoysa, Nicole M Isbel, Steven McTaggart, Alicia T Morrish, E Geoffrey Playford, Anish Scaria, Paul Snelling, Liza A Vergara, Carmel M Hawley. Antibacterial honey for the prevention of peritoneal-dialysis-related infections (HONEYPOT): a randomised trial. The Lancet. Infectious diseases. 2014 Jan; 14(1):23-30. doi: 10.1016/s1473-3099(13)70258-5. [PMID: 24119840]
  • Carina Vingsbo Lundberg, Niels Frimodt-Møller. Efficacy of topical and systemic antibiotic treatment of meticillin-resistant Staphylococcus aureus in a murine superficial skin wound infection model. International journal of antimicrobial agents. 2013 Sep; 42(3):272-5. doi: 10.1016/j.ijantimicag.2013.05.008. [PMID: 23837927]
  • I G Azcárate, P Marín-García, N Camacho, S Pérez-Benavente, A Puyet, A Diez, L Ribas de Pouplana, J M Bautista. Insights into the preclinical treatment of blood-stage malaria by the antibiotic borrelidin. British journal of pharmacology. 2013 Jun; 169(3):645-58. doi: 10.1111/bph.12156. [PMID: 23488671]
  • Ana Rocha, Anabela Rodrigues, Laetitia Teixeira, Maria João Carvalho, Denisa Mendonça, António Cabrita. Temporal trends in peritonitis rates, microbiology and outcomes: the major clinical complication of peritoneal dialysis. Blood purification. 2012; 33(4):284-91. doi: 10.1159/000337377. [PMID: 22572743]
  • K Souly, M Ait el kadi, K Lahmadi, H Biougnach, A Boughaidi, M Zouhdi, S Benasila, Z Elyoussefi, T Bouattar, N Zbiti, Z Skalli, H Rhou, N Ouzeddoun, R Bayahia, L Benamar. Epidemiology and prevention of Staphylococcus aureus nasal carriage in hemodialyzed patients. Medecine et maladies infectieuses. 2011 Sep; 41(9):469-74. doi: 10.1016/j.medmal.2011.05.005. [PMID: 21752563]
  • Elizabeth A C Haidar, Terence D Lee, Jonathan D Barton, Anthony R M Coates, Peter G Mantle. HPLC/MS/MS methodology for sensitive quantitation of monic acid A, the metabolic product of the antibiotic mupirocin. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 2011 Aug; 16(5):422-5. doi: 10.3109/1354750x.2011.582153. [PMID: 21595607]
  • Maria-Teresa Gutierrez-Lugo, Carole A Bewley. Susceptibility and mode of binding of the Mycobacterium tuberculosis cysteinyl transferase mycothiol ligase to tRNA synthetase inhibitors. Bioorganic & medicinal chemistry letters. 2011 Apr; 21(8):2480-3. doi: 10.1016/j.bmcl.2011.02.042. [PMID: 21392992]
  • M C Brown, R A Mactier. Concerns regarding routine use of sodium hypochlorite for exit-site care--what about the risks of encapsulating peritoneal sclerosis?. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. 2010 Jul; 30(4):480. doi: 10.3747/pdi.2009.00261. [PMID: 20628114]
  • Beth Piraino. Dialysis: The importance of peritoneal catheter exit-site care. Nature reviews. Nephrology. 2010 May; 6(5):259-60. doi: 10.1038/nrneph.2010.45. [PMID: 20424630]
  • O Bajolet, E Toussaint, S Diallo, V Vernet-Garnier, E Dehoux. [Is it possible to detect Staphylococcus aureus colonization or bacteriuria before orthopedic surgery hospitalization?]. Pathologie-biologie. 2010 Apr; 58(2):127-30. doi: 10.1016/j.patbio.2009.07.003. [PMID: 19892489]
  • Annabelle N Chua, Stuart L Goldstein, Deborah Bell, Eileen D Brewer. Topical mupirocin/sodium hypochlorite reduces peritonitis and exit-site infection rates in children. Clinical journal of the American Society of Nephrology : CJASN. 2009 Dec; 4(12):1939-43. doi: 10.2215/cjn.02770409. [PMID: 19820132]
  • Ali S Faqi, Stacie J Bell, Stan Gill, Dorothy B Colagiovanni. An intranasal irritation assessment of antibacterial ointment alone or in combination with mupirocin versus Bactroban Nasal in rabbits. Regulatory toxicology and pharmacology : RTP. 2009 Oct; 55(1):28-32. doi: 10.1016/j.yrtph.2009.05.017. [PMID: 19497343]
  • Alex van Belkum, Nelianne J Verkaik, Corné P de Vogel, Hélène A Boelens, Jeroen Verveer, Jan L Nouwen, Henri A Verbrugh, Heiman F L Wertheim. Reclassification of Staphylococcus aureus nasal carriage types. The Journal of infectious diseases. 2009 Jun; 199(12):1820-6. doi: 10.1086/599119. [PMID: 19419332]
  • Martti Vaara, John Fox, Günther Loidl, Osmo Siikanen, Juha Apajalahti, Frank Hansen, Niels Frimodt-Møller, Junya Nagai, Mikihisa Takano, Timo Vaara. Novel polymyxin derivatives carrying only three positive charges are effective antibacterial agents. Antimicrobial agents and chemotherapy. 2008 Sep; 52(9):3229-36. doi: 10.1128/aac.00405-08. [PMID: 18591267]
  • Abdulla K Al-Hwiesh, Ibrahiem Saeed Abdul Rahman. Prevention of staphylococcal peritonitis in CAPD patients combining ablution and mupirocin. Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia. 2008 Sep; 19(5):737-45. doi: NULL. [PMID: 18711288]
  • David James Najarian, Babar K Rao, Amy S Pappert. A case of mucous membrane plasmacytosis successfully treated with cryotherapy. Dermatology online journal. 2008 Feb; 14(2):6. doi: NULL. [PMID: 18700109]
  • Caner Cavdar, Funda Saglam, Aykut Sifil, Ali Celik, Tugba Atay, Ozkan Gungor, Ayse Ozder, Zeynep Gulay, Taner Camsari. Effect of once-a-week vs thrice-a-week application of mupirocin on methicillin and mupirocin resistance in peritoneal dialysis patients: three years of experience. Renal failure. 2008; 30(4):417-22. doi: 10.1080/08860220801964228. [PMID: 18569916]
  • David R Drake, Kim A Brogden, Deborah V Dawson, Philip W Wertz. Thematic review series: skin lipids. Antimicrobial lipids at the skin surface. Journal of lipid research. 2008 Jan; 49(1):4-11. doi: 10.1194/jlr.r700016-jlr200. [PMID: 17906220]
  • P F Chiou, C C Chang, Y K Wen, Y Yang. Antibiotic lock technique reduces the incidence of temporary catheter-related infections. Clinical nephrology. 2006 Jun; 65(6):419-22. doi: 10.5414/cnp65419. [PMID: 16792137]
  • Jin-Feng Hu, Eliane Garo, Grayson W Hough, Matt G Goering, Mark O'Neil-Johnson, Gary R Eldridge. Antibacterial, partially acetylated oligorhamnosides from Cleistopholis patens. Journal of natural products. 2006 Apr; 69(4):585-90. doi: 10.1021/np050438i. [PMID: 16643031]
  • Christopher Thiam-Seong Lim, Kok-Seng Wong, Marjore Wai-Yin Foo. The impact of topical mupirocin on peritoneal dialysis infection in Singapore General Hospital. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2005 Oct; 20(10):2202-6. doi: 10.1093/ndt/gfi010. [PMID: 16046516]
  • Sandeep Mahajan, Suresh C Tiwari, Vikram Kalra, Dipankar M Bhowmik, Sanjay K Agarwal, Suresh C Dash, Parveen Kumar. Effect of local mupirocin application on exit-site infection and peritonitis in an Indian peritoneal dialysis population. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. 2005 Sep; 25(5):473-7. doi: 10.1177/089686080502500512. [PMID: 16178481]
  • Christopher Thiam-Seong Lim, Kok-Seng Wong, Marjorie Wai-Yin Foo. The impact of topical mupirocin on peritoneal dialysis infection rates in Singapore General Hospital. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2005 Aug; 20(8):1702-6. doi: 10.1093/ndt/gfh860. [PMID: 15855200]
  • David Wayne Johnson, Carolyn van Eps, David William Mudge, Kathryn Joan Wiggins, Kirsty Armstrong, Carmel Mary Hawley, Scott Bryan Campbell, Nicole Maree Isbel, Graeme Robert Nimmo, Harry Gibbs. Randomized, controlled trial of topical exit-site application of honey (Medihoney) versus mupirocin for the prevention of catheter-associated infections in hemodialysis patients. Journal of the American Society of Nephrology : JASN. 2005 May; 16(5):1456-62. doi: 10.1681/asn.2004110997. [PMID: 15788475]
  • Judith Bernardini, Filitsa Bender, Tracey Florio, James Sloand, Linda Palmmontalbano, Linda Fried, Beth Piraino. Randomized, double-blind trial of antibiotic exit site cream for prevention of exit site infection in peritoneal dialysis patients. Journal of the American Society of Nephrology : JASN. 2005 Feb; 16(2):539-45. doi: 10.1681/asn.2004090773. [PMID: 15625071]
  • Michael Allon. Dialysis catheter-related bacteremia: treatment and prophylaxis. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2004 Nov; 44(5):779-91. doi: 10.1016/s0272-6386(04)01078-9. [PMID: 15492943]
  • G F M Strippoli, A Tong, D Johnson, F P Schena, J C Craig. Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients. The Cochrane database of systematic reviews. 2004 Oct; ?(4):CD004679. doi: 10.1002/14651858.cd004679.pub2. [PMID: 15495124]
  • Romina A Danguilan, Liezl P Evangelista, Mildred S Abrenica, Stella Marie S Rondilla. Comparative study of mupirocin and sodium fucidate in the prophylaxis of exit-site infections in CAPD patients. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. 2003 Nov; 23(6):593-5. doi: 10.1177/089686080302300614. [PMID: 14703203]
  • Shigeru Fujimura, Akira Watanabe. Survey of high- and low-level mupirocin-resistant strains of methicillin-resistant Staphylococcus aureus in 15 Japanese hospitals. Chemotherapy. 2003 May; 49(1-2):36-8. doi: 10.1159/000069780. [PMID: 12714808]
  • C Dupeyron, B Campillo, M Bordes, E Faubert, J-P Richardet, N Mangeney. A clinical trial of mupirocin in the eradication of methicillin-resistant Staphylococcus aureus nasal carriage in a digestive disease unit. The Journal of hospital infection. 2002 Dec; 52(4):281-7. doi: 10.1053/jhin.2002.1287. [PMID: 12473473]
  • Vidhya Rangaswamy, Gustavo Hernández-Guzmán, Kevin A Shufran, Carol L Bender. Analysis of rILERS, an isoleucyl-tRNA synthetase gene associated with mupirocin production by Pseudomonas fluorescens NCIMB 10586. DNA sequence : the journal of DNA sequencing and mapping. 2002 Dec; 13(6):343-51. doi: 10.1080/1042517021000033399. [PMID: 12652905]
  • S J Peacock, S Mandal, I C J W Bowler. Preventing Staphylococcus aureus infection in the renal unit. QJM : monthly journal of the Association of Physicians. 2002 Jun; 95(6):405-10. doi: 10.1093/qjmed/95.6.405. [PMID: 12037249]
  • Miguel Pérez-Fontán, Miguel Rosales, Ana Rodríguez-Carmona, Teresa García Falcón, Francisco Valdés. Mupirocin resistance after long-term use for Staphylococcus aureus colonization in patients undergoing chronic peritoneal dialysis. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2002 Feb; 39(2):337-41. doi: 10.1053/ajkd.2002.30553. [PMID: 11840374]
  • R Annigeri, J Conly, S Vas, H Dedier, K P Prakashan, J M Bargman, V Jassal, D Oreopoulos. Emergence of mupirocin-resistant Staphylococcus aureus in chronic peritoneal dialysis patients using mupirocin prophylaxis to prevent exit-site infection. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. 2001 Nov; 21(6):554-9. doi: 10.1177/089686080102100604. [PMID: 11783763]
  • K P Prakashan, R A Annigeri, M Chu, J M Bargman, S I Vas, D G Oreopoulos. Local application of mupirocin at the peritoneal catheter exit site prevents early postoperative infections and should become standard practice. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. 2001 Sep; 21(5):526-7. doi: NULL. [PMID: 11757842]
  • S Harbarth, S Dharan, N Liassine, P Herrault, R Auckenthaler, D Pittet. Randomized, placebo-controlled, double-blind trial to evaluate the efficacy of mupirocin for eradicating carriage of methicillin-resistant Staphylococcus aureus. Antimicrobial agents and chemotherapy. 1999 Jun; 43(6):1412-6. doi: 10.1128/aac.43.6.1412. [PMID: 10348762]
  • J Bernardini, B Piraino, J Holley, J R Johnston, R Lutes. A randomized trial of Staphylococcus aureus prophylaxis in peritoneal dialysis patients: mupirocin calcium ointment 2\% applied to the exit site versus cyclic oral rifampin. American journal of kidney diseases : the official journal of the National Kidney Foundation. 1996 May; 27(5):695-700. doi: 10.1016/s0272-6386(96)90105-5. [PMID: 8629630]
  • B S Bloom, A M Fendrick, M E Chernew, P Patel. Clinical and economic effects of mupirocin calcium on preventing Staphylococcus aureus infection in hemodialysis patients: a decision analysis. American journal of kidney diseases : the official journal of the National Kidney Foundation. 1996 May; 27(5):687-94. doi: 10.1016/s0272-6386(96)90104-3. [PMID: 8629629]
  • M S Terpenning, S F Bradley, J Y Wan, C E Chenoweth, K A Jorgensen, C A Kauffman. Colonization and infection with antibiotic-resistant bacteria in a long-term care facility. Journal of the American Geriatrics Society. 1994 Oct; 42(10):1062-9. doi: 10.1111/j.1532-5415.1994.tb06210.x. [PMID: 7930330]
  • M Pérez-Fontán, T García-Falcón, M Rosales, A Rodríguez-Carmona, M Adeva, I Rodríguez-Lozano, J Moncalián. Treatment of Staphylococcus aureus nasal carriers in continuous ambulatory peritoneal dialysis with mupirocin: long-term results. American journal of kidney diseases : the official journal of the National Kidney Foundation. 1993 Nov; 22(5):708-12. doi: 10.1016/s0272-6386(12)80434-3. [PMID: 8238017]
  • A L Barry, M A Pfaller, P C Fuchs. Ramoplanin susceptibility testing criteria. Journal of clinical microbiology. 1993 Jul; 31(7):1932-5. doi: 10.1128/jcm.31.7.1932-1935.1993. [PMID: 8349779]
  • C Palacios, R E Reyes, R López-Martínez, B de León, J L Pablos, R Ruiz-Maldonado. [Cicatricial, antibacterial and antimycotic effects of tepescohuite in experimental animals]. Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion. 1991 Jul; 43(3):205-10. doi: ". [PMID: 1818366]
  • M A Watcher, R G Wheeland. The role of topical agents in the healing of full-thickness wounds. The Journal of dermatologic surgery and oncology. 1989 Nov; 15(11):1188-95. doi: 10.1111/j.1524-4725.1989.tb03232.x. [PMID: 2509527]
  • A Kaukas, M Hinton. The influence of the growth promoting antibiotic mupirocin on the enterococci of fattening pigs. The British veterinary journal. 1988 May; 144(3):302-9. doi: 10.1016/0007-1935(88)90117-0. [PMID: 3135911]
  • A K Balin, I Leong, D M Carter. Effect of mupirocin on the growth and lifespan of human fibroblasts. The Journal of investigative dermatology. 1987 Jun; 88(6):736-40. doi: 10.1111/1523-1747.ep12470407. [PMID: 3108412]
  • L D Eells, P M Mertz, Y Piovanetti, G M Pekoe, W H Eaglstein. Topical antibiotic treatment of impetigo with mupirocin. Archives of dermatology. 1986 Nov; 122(11):1273-6. doi: NULL. [PMID: 3096221]
  • R Sutherland, R J Boon, K E Griffin, P J Masters, B Slocombe, A R White. Antibacterial activity of mupirocin (pseudomonic acid), a new antibiotic for topical use. Antimicrobial agents and chemotherapy. 1985 Apr; 27(4):495-8. doi: 10.1128/aac.27.4.495. [PMID: 3923922]