betaxolol (BioDeep_00000398417)
Main id: BioDeep_00000001908
代谢物信息卡片
betaxolol
化学式: C18H29NO3 (307.2147)
中文名称: 倍他洛尔
谱图信息:
最多检出来源 Mus musculus(urine) 13.3%
分子结构信息
SMILES: CC(C)NCC(COC1=CC=C(C=C1)CCOCC2CC2)O
InChI: InChI=1S/C18H29NO3/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3
描述信息
C - Cardiovascular system > C07 - Beta blocking agents > C07A - Beta blocking agents > C07AB - Beta blocking agents, selective
S - Sensory organs > S01 - Ophthalmologicals > S01E - Antiglaucoma preparations and miotics > S01ED - Beta blocking agents
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013565 - Sympatholytics
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists
D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
Betaxolol is a selective beta1 adrenergic receptor blocker that can be used for the research of hypertension and glaucoma.
同义名列表
数据库引用编号
26 个数据库交叉引用编号
- ChEBI: CHEBI:3082
- KEGG: C75987
- KEGG: C06849
- KEGGdrug: D07526
- PubChem: 2369
- DrugBank: DB00195
- ChEMBL: CHEMBL423
- MeSH: Betaxolol
- CAS: 108008-51-1
- CAS: 63659-18-7
- MoNA: WA001972
- MoNA: WA001971
- MoNA: WA001970
- MoNA: WA001969
- MoNA: WA001968
- MoNA: FiehnHILIC001795
- MoNA: FiehnHILIC000222
- MoNA: CO000080
- MoNA: CO000079
- MoNA: CO000078
- MoNA: CO000077
- MoNA: CO000076
- PubChem: 9067
- NIKKAJI: J19.271F
- medchemexpress: HY-B0381
- KNApSAcK: 3082
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
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文献列表
- Huamei Li, Fuda Dai, Hanyu Liu, Qi Tao, Jie Hu, Yangrong Zhang, Zhenping Xiao, Ilva D Rupenthal, Huihui Li, Fan Yang, Wei Li, Huaqing Lin, Dongzhi Hou. Physicochemical properties and micro-interaction between micro-nanoparticles and anterior corneal multilayer biological interface film for improving drug delivery efficacy: the transformation of tear film turnover mode.
Drug delivery.
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Cell reports.
2021 04; 35(4):109040. doi:
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Profiles of drug substances, excipients, and related methodology.
2021; 46(?):91-136. doi:
10.1016/bs.podrm.2020.07.002. [PMID: 33461701] - Shuo Liu, Xinyue Han, Hanyu Liu, Yawen Zhao, Huamei Li, Ilva D Rupenthal, Zhufen Lv, Yanzhong Chen, Fan Yang, Qineng Ping, Yufang Pan, Dongzhi Hou. Incorporation of ion exchange functionalized-montmorillonite into solid lipid nanoparticles with low irritation enhances drug bioavailability for glaucoma treatment.
Drug delivery.
2020 Dec; 27(1):652-661. doi:
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International journal of pharmaceutics.
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Analytical and bioanalytical chemistry.
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Talanta.
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European journal of emergency medicine : official journal of the European Society for Emergency Medicine.
2007 Apr; 14(2):120-2. doi:
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International journal of cardiology.
2006 Nov; 113(2):153-60. doi:
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Investigative ophthalmology & visual science.
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Synapse (New York, N.Y.).
2003 Jul; 49(1):67-76. doi:
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Likars'ka sprava.
2003 Jul; ?(5-6):90-2. doi:
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Journal of cardiovascular pharmacology.
2003 Jan; 41 Suppl 1(?):S99-103. doi:
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Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics.
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Investigative ophthalmology & visual science.
1999 Feb; 40(2):370-7. doi:
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Journal of analytical toxicology.
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Acta ophthalmologica.
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Experimental eye research.
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Acta ophthalmologica.
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Japanese journal of pharmacology.
1992 Nov; 60(3):253-9. doi:
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Diabetes care.
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