Chlorfenvinfos (BioDeep_00000398382)
代谢物信息卡片
化学式: C12H14Cl3O4P (357.96952640000006)
中文名称: 毒虫畏
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCOP(=O)(OCC)OC(=CCl)C1=C(C=C(C=C1)Cl)Cl
InChI: InChI=1S/C12H14Cl3O4P/c1-3-17-20(16,18-4-2)19-12(8-13)10-6-5-9(14)7-11(10)15/h5-8H,3-4H2,1-2H3
描述信息
ORIGINAL_ACQUISITION_NO 9710; CONFIDENCE standard compound; INTERNAL_ID 376; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_PRECURSOR_SCAN_NO 9708
CONFIDENCE standard compound; INTERNAL_ID 376; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9710; ORIGINAL_PRECURSOR_SCAN_NO 9708
D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D002800 - Cholinesterase Inhibitors
D010575 - Pesticides > D007306 - Insecticides
D010575 - Pesticides > D056810 - Acaricides
D004791 - Enzyme Inhibitors
D016573 - Agrochemicals
CONFIDENCE standard compound; INTERNAL_ID 376; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9724; ORIGINAL_PRECURSOR_SCAN_NO 9721
CONFIDENCE standard compound; INTERNAL_ID 376; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9748; ORIGINAL_PRECURSOR_SCAN_NO 9745
CONFIDENCE standard compound; INTERNAL_ID 376; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9768; ORIGINAL_PRECURSOR_SCAN_NO 9766
CONFIDENCE standard compound; INTERNAL_ID 376; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9748; ORIGINAL_PRECURSOR_SCAN_NO 9744
CONFIDENCE standard compound; INTERNAL_ID 376; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9777; ORIGINAL_PRECURSOR_SCAN_NO 9774
CONFIDENCE standard compound; INTERNAL_ID 2609
CONFIDENCE standard compound; INTERNAL_ID 4038
同义名列表
3 个代谢物同义名
数据库引用编号
21 个数据库交叉引用编号
- ChEBI: CHEBI:38598
- PubChem: 10107
- ChEMBL: CHEMBL2354650
- MeSH: Chlorfenvinphos
- CAS: 470-90-6
- MoNA: LU037606
- MoNA: LU037605
- MoNA: LU037604
- MoNA: LU037603
- MoNA: LU037602
- MoNA: LU037601
- MoNA: AU260906
- MoNA: AU260905
- MoNA: AU260904
- MoNA: AU260903
- MoNA: AU260902
- MoNA: AU260901
- MoNA: UF403804
- MoNA: UF403803
- MoNA: UF403802
- MoNA: UF403801
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964
. [PMID: 31515284] - Lewis Couchman, John A Slaughter, Gemma Coombes, Atholl Johnston, Evans Ogoti, David W Holt. The Smell of Death: An Unusual Case of Poisoning With the Organophosphorus Pesticide Chlorfenvinphos.
Therapeutic drug monitoring.
2019 04; 41(2):250-252. doi:
10.1097/ftd.0000000000000584
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Veterinary parasitology.
2017 Jan; 234(?):10-12. doi:
10.1016/j.vetpar.2016.12.014
. [PMID: 28115176] - Bożena Sosnowska, Bogumiła Huras, Bożena Bukowska. Oxidative stress in human erythrocytes treated with bromfenvinphos and its impurities.
Pesticide biochemistry and physiology.
2015 Feb; 118(?):43-9. doi:
10.1016/j.pestbp.2014.11.009
. [PMID: 25752429] - María Hijosa-Valsero, Ricardo Molina, Hendrik Schikora, Michael Müller, Josep M Bayona. Removal of priority pollutants from water by means of dielectric barrier discharge atmospheric plasma.
Journal of hazardous materials.
2013 Nov; 262(?):664-73. doi:
10.1016/j.jhazmat.2013.09.022
. [PMID: 24121639] - Radosław Swiercz, Piotr Lutz, Sławomir Gralewicz, Zofia Grzelińska, Joanna Piasecka-Zelga, Wojciech Wąsowicz. Partial protection from organophosphate-induced cholinesterase inhibition by metyrapone treatment.
International journal of occupational medicine and environmental health.
2013 Aug; 26(4):636-46. doi:
10.2478/s13382-013-0131-1
. [PMID: 24052154] - Alicja Roszczenko, Joanna Rogalska, Janina Moniuszko-Jakoniuk, Malgorzata M Brzóska. The effect of exposure to chlorfenvinphos on lipid metabolism and apoptotic and necrotic cells death in the brain of rats.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
2013 Jul; 65(5):531-9. doi:
10.1016/j.etp.2012.03.002
. [PMID: 22498023] - Anna Lukaszewicz-Hussain. [Serum glucose concentration in subacute intoxication with chlorpyrifos - organophosphate insecticide].
Medycyna pracy.
2013; 64(4):527-31. doi:
10.13075/mp.5893.2013.0043
. [PMID: 24502117] - María A Martínez, Salomé Ballesteros. Two suicidal fatalities due to the ingestion of chlorfenvinphos formulations: simultaneous determination of the pesticide and the petroleum distillates in tissues by gas chromatography-flame-ionization detection and gas chromatography-mass spectrometry.
Journal of analytical toxicology.
2012 Jan; 36(1):44-51. doi:
10.1093/jat/bkr014
. [PMID: 22290752] - Anna Łukaszewicz-Hussain. [Paraoxonase activity and lipid peroxides concentration in serum of rats subchronically intoxicated with chlorpyrifos--organophosphate insecticide].
Medycyna pracy.
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International journal of occupational medicine and environmental health.
2011 Sep; 24(3):283-91. doi:
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Journal of chromatography. A.
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. [PMID: 21134677] - Anna Łukaszewicz-Hussain. [Liver and serum glutathione concentration and liver hydrogen peroxide in rats subchronically intoxicated with chlorfenvinphos--organophosphate insecticide].
Medycyna pracy.
2011; 62(1):23-9. doi:
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Ecotoxicology (London, England).
2010 Jun; 19(5):855-63. doi:
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Bulletin of environmental contamination and toxicology.
2010 May; 84(5):582-6. doi:
10.1007/s00128-010-9984-1
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Environmental science & technology.
2010 Mar; 44(5):1792-8. doi:
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Annals of agricultural and environmental medicine : AAEM.
2010; 17(1):65-71. doi:
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Journal of agricultural and food chemistry.
2009 May; 57(10):4079-90. doi:
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Journal of chromatography. A.
2008 Jul; 1196-1197(?):100-9. doi:
10.1016/j.chroma.2008.02.087
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Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.
2008 Jun; 13(4):343-63. doi:
10.1080/13547500801973563
. [PMID: 18484351] - Anna Lukaszewicz-Hussain. Subchronic intoxication with chlorfenvinphos, an organophosphate insecticide, affects rat brain antioxidative enzymes and glutathione level.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2008 Jan; 46(1):82-6. doi:
10.1016/j.fct.2007.06.038
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Chemistry & biodiversity.
2007 Sep; 4(9):2218-24. doi:
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Chemosphere.
2007 Jan; 66(6):993-1002. doi:
10.1016/j.chemosphere.2006.07.051
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Journal of hazardous materials.
2006 Nov; 138(2):363-9. doi:
10.1016/j.jhazmat.2006.05.058
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Aquatic toxicology (Amsterdam, Netherlands).
2006 Jun; 78(3):243-52. doi:
10.1016/j.aquatox.2006.03.007
. [PMID: 16672166] - Milena Lapertot, César Pulgarín, Pilar Fernández-Ibáñez, Manuel I Maldonado, Leonidas Pérez-Estrada, Isabel Oller, Wolfgang Gernjak, Sixto Malato. Enhancing biodegradability of priority substances (pesticides) by solar photo-Fenton.
Water research.
2006 Mar; 40(5):1086-94. doi:
10.1016/j.watres.2006.01.002
. [PMID: 16469356] - Howard C Bailey, James R Elphick, Rick Krassoi, Ann-Marie Mulhall, Adam J Lovell, Daniel J Slee. Identification of chlorfenvinphos toxicity in a municipal effluent in Sydney, New South Wales, Australia.
Environmental toxicology and chemistry.
2005 Jul; 24(7):1773-8. doi:
10.1897/04-366r.1
. [PMID: 16050596] - Sławomir Gralewicz, Piotr Lutz, Barbara Kur. Pretreatment with footshock alters some effects of subsequent organophosphate exposure.
Neurotoxicology.
2005 Mar; 26(2):159-71. doi:
10.1016/j.neuro.2004.12.003
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Biosensors & bioelectronics.
2002 Sep; 17(9):815-9. doi:
10.1016/s0956-5663(02)00074-x
. [PMID: 12191930] - S Kossmann, B Konieczny. [Serum immunoglobulin E concentration in workers producing chlorfenvinphos].
Przeglad lekarski.
2001; 58 Suppl 7(?):49-50. doi:
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- B Konieczny, S Kossmann, M Makuch. Impaired respiratory muscle function in chemical plant workers producing chlorfenvinphos.
Annals of agricultural and environmental medicine : AAEM.
1999; 6(1):21-5. doi:
. [PMID: 10384211]
- R Soćko, S Gralewicz, R Górny. Long-term behavioural effects of a repeated exposure to chlorphenvinphos in rats.
International journal of occupational medicine and environmental health.
1999; 12(2):105-17. doi:
. [PMID: 10465900]
- A Lukaszewicz-Hussain, J Moniuszko-Jakoniuk. [The impact of acute poisoning by chlorfenvinphos on the activity of antioxidant enzymes and concentration of malondialdehyde in rats].
Roczniki Panstwowego Zakladu Higieny.
1999; 50(3):307-11. doi:
. [PMID: 10628227]
- P K Mohapatra, U Schiewer. Effect of dimethoate and chlorfenvinphos on plasma membrane integrity of Synechocystis sp. PCC 6803.
Ecotoxicology and environmental safety.
1998 Nov; 41(3):269-74. doi:
10.1006/eesa.1998.1708
. [PMID: 9799578] - A Lukaszewicz-Hussain, J Moniuszko-Jakoniuk. [Changes in rats liver in late period of intoxication with chlorphenvinphos in a single dose].
Roczniki Panstwowego Zakladu Higieny.
1998; 49(3):313-9. doi:
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Przeglad lekarski.
1997; 54(10):719-22. doi:
NULL
. [PMID: 9478093] - P Kłuciński, S Kossmann, D Friedek. Release of interleukin-1 beta from peripheral blood monocytes and its concentration in the blood serum of the workers employed at the production of chlorfenvinphos.
Przeglad lekarski.
1997; 54(10):716-8. doi:
. [PMID: 9478092]
- S Kossmann, E Cierpka, Z Szwed. Biochemical evaluation of the liver function in workers employed at the production of chlorfenvinphos.
Przeglad lekarski.
1997; 54(10):712-5. doi:
. [PMID: 9478091]
- L Sedrowicz, D Witkowska, R Oledzka. Effect of chlorfenvinphos, cypermethrin and their mixture on the intestinal transport of leucine and methionine.
Journal of applied toxicology : JAT.
1996 Nov; 16(6):483-9. doi:
10.1002/(sici)1099-1263(199611)16:6<483::aid-jat380>3.0.co;2-d
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The Veterinary record.
1995 Mar; 136(9):217-20. doi:
10.1136/vr.136.9.217
. [PMID: 7771071] - K I Zaleska-Freljan, J T Wolewicz. Influence of bromfenvinphos alone, and in mixture with methoxychlor, on levels of gamma-glutamyl transpeptidase, ceruloplasmin and cholesterol in the blood plasma of laboratory mice.
Polish journal of pharmacology.
1993 May; 45(3):309-16. doi:
NULL
. [PMID: 8106090] - J Dudka, S Szczepaniak. [Investigation of chlorfenvinphos influence on levels of free tryptophan in blood plasma of the rat].
Roczniki Panstwowego Zakladu Higieny.
1993; 44(2-3):199-203. doi:
NULL
. [PMID: 8016542] - J Błasiak. Changes in the fluidity of model lipid membranes evoked by the organophosphorus insecticide methylbromfenvinfos.
Acta biochimica Polonica.
1993; 40(1):39-41. doi:
"
. [PMID: 8372562] - M A Chishti, T Rotkiewicz. Hepatic and renal ultrastructural changes in cockerels exposed to cadmium chloride and subsequent interaction with organophosphate insecticide.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer.
1993 Jan; 12(1):35-45. doi:
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Archives of environmental contamination and toxicology.
1992 May; 22(4):445-51. doi:
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. [PMID: 1586206] - T Ikeda, S Tsuda, Y Shirasu. Pharmacokinetic analysis of protection by an organophosphorus insecticide, chlorfenvinphos, against the toxicity of its succeeding dosage in rats.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1992 Feb; 18(2):299-306. doi:
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. [PMID: 1601231] - J Rouchaud, F Gustin, F Benoit, N Ceustermans, J Gillet, F Van de Steene, C Pelerents. Influence of cow manure and composts on the effects of chlorfenvinphos on field crops.
Archives of environmental contamination and toxicology.
1992 Jan; 22(1):122-9. doi:
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Roczniki Panstwowego Zakladu Higieny.
1992; 43(1):67-73. doi:
NULL
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Fundamental and applied toxicology : official journal of the Society of Toxicology.
1991 Aug; 17(2):361-7. doi:
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Polish journal of occupational medicine and environmental health.
1991; 4(2):183-96. doi:
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Polish journal of occupational medicine and environmental health.
1991; 4(4):359-75. doi:
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Fundamental and applied toxicology : official journal of the Society of Toxicology.
1990 Apr; 14(3):560-7. doi:
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Roczniki Akademii Medycznej w Bialymstoku = Annales Academiae Medicae Bialostocensis.
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. [PMID: 2136543] - S Gralewicz, W Kowalczyk, R Górny, R Soćko. Brain electrical activity (EEG) after repetitive exposure to chlorphenvinphos an organophosphate anticholinesterase: I. Rabbit.
Polish journal of occupational medicine.
1990; 3(1):51-67. doi:
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Bulletin of environmental contamination and toxicology.
1989 Dec; 43(6):920-8. doi:
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. [PMID: 2597799] - S Gralewicz, T Tomas, R Górny, W Kowalczyk, R Soćko. Changes in physiological and electrophysiological parameters in rabbits after single exposure to chlorphenvinphos.
Polish journal of occupational medicine.
1989; 2(1):3-14. doi:
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Polish journal of occupational medicine.
1989; 2(3):294-308. doi:
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Polish journal of pharmacology and pharmacy.
1987 Jul; 39(4):361-70. doi:
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Acta microbiologica Bulgarica.
1987; 20(?):81-7. doi:
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1985 Jun; 20(3):321-40. doi:
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Journal of applied toxicology : JAT.
1984 Oct; 4(5):261-4. doi:
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. [PMID: 6512163] - A Osicka-Koprowska, M Lipska, B Wysocka-Paruszewska. Effects of chlorfenvinphos on plasma corticosterone and aldosterone levels in rats.
Archives of toxicology.
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Die Nahrung.
1984; 28(5):473-82. doi:
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