Ethynyl estradiol (BioDeep_00000397810)

Main id: BioDeep_00000002826

 

PANOMIX_OTCML-2023


代谢物信息卡片


17a-Ethynylestradiol

化学式: C20H24O2 (296.1776)
中文名称: 炔雌醇
谱图信息: 最多检出来源 Homo sapiens(blood) 31.12%

分子结构信息

SMILES: C#C[C@]1(O)CC[C@H]2[C@@H]3CCc4cc(O)ccc4[C@H]3CC[C@@]21C
InChI: InChI=1S/C20H24O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,5,7,12,16-18,21-22H,4,6,8-11H2,2H3

描述信息

G - Genito urinary system and sex hormones > G03 - Sex hormones and modulators of the genital system > G03C - Estrogens > G03CA - Natural and semisynthetic estrogens, plain
L - Antineoplastic and immunomodulating agents > L02 - Endocrine therapy > L02A - Hormones and related agents > L02AA - Estrogens
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D004967 - Estrogens
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C483 - Therapeutic Estrogen
D012102 - Reproductive Control Agents > D003270 - Contraceptive Agents
COVID info from COVID-19 Disease Map
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
Disclaimer: While authors make an effort to ensure that the content of this record is accurate, the authors make no representations or warranties in relation to the accuracy or completeness of the record. This record do not reflect any viewpoints of the affiliation and organization to which the authors belong.
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3065
EAWAG_UCHEM_ID 3065; CONFIDENCE standard compound
Ethinylestradiol (Ethynyl estradiol) is a biologically active estrogen. Ethinylestradiol is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Ethinylestradiol (Ethynyl estradiol) is a biologically active estrogen. Ethinylestradiol is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

同义名列表

6 个代谢物同义名

Ethynyl estradiol; Ethinyl estradiol; 17a-Ethynylestradiol; 17α-Ethynylestradiol; Ethinylestradiol; Ethynyl estradiol



数据库引用编号

35 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

69 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 AHR, ALB, AR, BGLAP, CYP3A4, DSG1, PGR, PRL
Endoplasmic reticulum membrane 1 CYP3A4
Nucleus 7 AHR, ALB, AR, DSG1, ESR2, PGR, PRL
cytosol 6 AHR, ALB, AR, DSG1, GPT, PGR
dendrite 1 BGLAP
centrosome 1 ALB
nucleoplasm 6 AHR, AR, ATP2B1, ESR2, PGR, PRL
RNA polymerase II transcription regulator complex 1 PRL
Cell membrane 3 ATP2B1, DSG1, TNF
Multi-pass membrane protein 1 ATP2B1
Synapse 1 ATP2B1
cell surface 2 PLG, TNF
glutamatergic synapse 2 ATP2B1, PLG
Golgi apparatus 1 ALB
Golgi membrane 1 INS
neuronal cell body 1 TNF
presynaptic membrane 1 ATP2B1
plasma membrane 9 AR, ATP2B1, DSG1, F2, GCG, PGR, PLG, REN, TNF
synaptic vesicle membrane 1 ATP2B1
Membrane 4 AR, ATP2B1, CYP3A4, REN
apical plasma membrane 1 DSG1
basolateral plasma membrane 1 ATP2B1
extracellular exosome 6 ALB, ATP2B1, F2, GPT, PLG, SERPINA6
endoplasmic reticulum 1 ALB
extracellular space 12 ALB, BGLAP, CRP, F2, GCG, GNRH1, INS, PLG, PRL, REN, SERPINA6, TNF
Schaffer collateral - CA1 synapse 1 PLG
mitochondrion 1 ESR2
protein-containing complex 3 AHR, ALB, AR
intracellular membrane-bounded organelle 3 ATP2B1, CYP3A4, ESR2
Microsome membrane 1 CYP3A4
Single-pass type I membrane protein 1 DSG1
Secreted 9 ALB, BGLAP, CRP, F2, GCG, INS, PLG, PRL, REN
extracellular region 12 ALB, BGLAP, CRP, F2, GCG, GNRH1, INS, PLG, PRL, REN, SERPINA6, TNF
cytoplasmic side of plasma membrane 1 DSG1
mitochondrial outer membrane 1 PGR
anchoring junction 1 ALB
transcription regulator complex 1 AHR
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
external side of plasma membrane 2 PLG, TNF
perikaryon 1 BGLAP
apical part of cell 1 REN
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 BGLAP
Membrane raft 1 TNF
collagen-containing extracellular matrix 2 F2, PLG
lateral plasma membrane 2 ATP2B1, DSG1
nuclear speck 1 AR
ciliary basal body 1 ALB
chromatin 5 AHR, AR, ESR2, PGR, PRL
cell projection 1 ATP2B1
phagocytic cup 1 TNF
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 3 ALB, F2, PLG
Basolateral cell membrane 1 ATP2B1
endosome lumen 2 INS, PRL
Cornified envelope 1 DSG1
aryl hydrocarbon receptor complex 1 AHR
Presynaptic cell membrane 1 ATP2B1
secretory granule lumen 2 GCG, INS
Golgi lumen 3 BGLAP, F2, INS
endoplasmic reticulum lumen 5 ALB, BGLAP, F2, GCG, INS
platelet alpha granule lumen 2 ALB, PLG
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
immunological synapse 1 ATP2B1
ficolin-1-rich granule membrane 1 DSG1
Cell junction, desmosome 1 DSG1
desmosome 1 DSG1
[Glucagon-like peptide 1]: Secreted 1 GCG
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
[Isoform 4]: Mitochondrion outer membrane 1 PGR
photoreceptor ribbon synapse 1 ATP2B1
nuclear aryl hydrocarbon receptor complex 1 AHR
cytosolic aryl hydrocarbon receptor complex 1 AHR
ciliary transition fiber 1 ALB
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Franca Fruzzetti, Tiziana Fidecicchi, Marco Gambacciani. Oestrogens in oral contraception: considerations for tailoring prescription to women's needs. The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception. 2024 Jun; 29(3):93-102. doi: 10.1080/13625187.2024.2334350. [PMID: 38683756]
  • Linshuang Wang, Fengxue Qu, Xueyun Yu, Sixia Yang, Binbin Zhao, Yaojing Chen, Pengbo Li, Zhanjun Zhang, Junying Zhang, Xuejie Han, Dongfeng Wei. Cortical lipid metabolic pathway alteration of early Alzheimer's disease and candidate drugs screen. European journal of medical research. 2024 Mar; 29(1):199. doi: 10.1186/s40001-024-01730-w. [PMID: 38528586]
  • Maha B Salem, Dina Mostafa Mohammed, Olfat A Hammam, Mohamed Elzallat. Mitigation of intrahepatic cholestasis induced by 17α-ethinylestradiol via nanoformulation of Silybum marianum L. BMC complementary medicine and therapies. 2024 Jan; 24(1):51. doi: 10.1186/s12906-024-04351-2. [PMID: 38263002]
  • Chandra Prakash, Vivek Kumar, Venkatesh Chaturvedi. Efficient removal of endocrine disrupting compounds 17 α-ethynyl estradiol and 17 β-estradiol by Enterobacter sp. strain BHUBP7 and elucidation of the degradation pathway by HRAMS analysis. World journal of microbiology & biotechnology. 2023 Jun; 39(8):218. doi: 10.1007/s11274-023-03662-9. [PMID: 37269502]
  • Nagihan E Korkmaz, Nuray Balkis Caglar, Abdullah Aksu, Tuba Unsal, Esra Billur Balcıoglu, Hande Cavus Arslan, Nazli Demirel. Occurrence, bioconcentration, and human health risks of pharmaceuticals in biota in the Sea of Marmara, Türkiye. Chemosphere. 2023 Jun; 325(?):138296. doi: 10.1016/j.chemosphere.2023.138296. [PMID: 36898445]
  • João A Rodrigues, Mónica Silva, Rita Araújo, Leonor Madureira, Amadeu M V M Soares, Rosa Freitas, Ana M Gil. The influence of temperature rise on the metabolic response of Ruditapes philippinarum clams to 17-α-ethinylestradiol. The Science of the total environment. 2023 Mar; 877(?):162898. doi: 10.1016/j.scitotenv.2023.162898. [PMID: 36934939]
  • Carlo Pretti, Paolo Aretini, Francesca Lessi, Rosa Freitas, Carlos Barata, Lucia De Marchi, Alessia Cuccaro, Matteo Oliva, Valentina Meucci, Mariella Baratti. Gene expression and biochemical patterns in the digestive gland of the mussel Mytilus galloprovincialis (Lamarck, 1819) exposed to 17α-ethinylestradiol. Aquatic toxicology (Amsterdam, Netherlands). 2023 Jan; 254(?):106376. doi: 10.1016/j.aquatox.2022.106376. [PMID: 36566548]
  • Wagner Antonio Tamagno, Carla Alves, Ana Paula Vanin, Denise Bilibio, Amanda Carolina Cole Varela, Mateus Timbola Mozzato, Leonardo José Gil Barcellos. Dietary transference of 17α-ethinylestradiol changes the biochemical and behavioral biomarkers in adult zebrafish (Danio rerio). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2022 Dec; 262(?):109472. doi: 10.1016/j.cbpc.2022.109472. [PMID: 36167257]
  • Emmanuel Stephen Odinga, Xian Zhou, Evance Omondi Mbao, Qurban Ali, Michael Gatheru Waigi, Margaret L Shiraku, Wanting Ling. Distribution, ecological fate, and risks of steroid estrogens in environmental matrices. Chemosphere. 2022 Dec; 308(Pt 2):136370. doi: 10.1016/j.chemosphere.2022.136370. [PMID: 36113656]
  • Noura Al-Jandal, Abdulaziz AlKhubaizi, Talat Saeed, Mariam Hajeyah. Potential Adsorption Affinity of Estrogens on LDPE and PET Microplastics Exposed to Wastewater Treatment Plant Effluents. International journal of environmental research and public health. 2022 Nov; 19(23):. doi: 10.3390/ijerph192316027. [PMID: 36498100]
  • Kristina Gemzell-Danielsson, Angelo Cagnacci, Nathalie Chabbert-Buffet, Jonathan Douxfils, Jean-Michel Foidart, Ali Kubba, Luis Ignacio Lete Lasa, Diana Mansour, Joseph Neulen, Jaoquim Neves, Fátima Palma, Thomas Römer, Robert Spaczyński, Vera Tóth. A novel estetrol-containing combined oral contraceptive: European expert panel review. The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception. 2022 Oct; 27(5):373-383. doi: 10.1080/13625187.2022.2093850. [PMID: 35862627]
  • Ganesh Cherala, Cara Nelson, Ying Guo, Anubhav Mathur, Thomas Tarnowski, Ahmed A Othman. Evaluation of the potential for pharmacokinetic interaction between tirabrutinib and levonorgestrel/ethinyl estradiol in healthy female volunteers. Clinical and translational science. 2022 06; 15(6):1492-1499. doi: 10.1111/cts.13265. [PMID: 35266297]
  • Shiyang Zhu, Xiao Ma, Xuesong Ding, Jingwen Gan, Yan Deng, Yanfang Wang, Aijun Sun. Comparative evaluation of low-level light therapy and ethinyl estradiol and desogestrel combined oral contraceptive for clinical efficacy and regulation of serum biochemical parameters in primary dysmenorrhoea: a prospective randomised multicentre trial. Lasers in medical science. 2022 Jun; 37(4):2239-2248. doi: 10.1007/s10103-021-03490-z. [PMID: 35028764]
  • S N Bliss, K Berger, J Thieme, M Maldonado Cobos, M Nyman. Removal of 17α-ethynylestradiol and β-estradiol using bench-scale constructed wetlands. Water science and technology : a journal of the International Association on Water Pollution Research. 2022 Jun; 85(12):3408-3418. doi: 10.2166/wst.2022.177. [PMID: 35771054]
  • Iago Santos Mesquita, Cristiano Piacsek Borges, Fabiana Valéria da Fonseca. Membrane biorreactor, reverse osmosis and UV/H2O2 process integration for ethinylestradiol removal: A cost-benefit analysis. Journal of environmental management. 2022 May; 310(?):114760. doi: 10.1016/j.jenvman.2022.114760. [PMID: 35219206]
  • Anne-Sophie Voisin, Victoria Suarez Ulloa, Peter Stockwell, Aniruddha Chatterjee, Frédéric Silvestre. Genome-wide DNA methylation of the liver reveals delayed effects of early-life exposure to 17-α-ethinylestradiol in the self-fertilizing mangrove rivulus. Epigenetics. 2022 05; 17(5):473-497. doi: 10.1080/15592294.2021.1921337. [PMID: 33892617]
  • Zainab Syed, Monika Sogani, Anu Kumar, Jayana Rajvanshi, Gopesh Sharma, Kumar Sonu. Biodegradation of synthetic estrogen using bioelectrochemical system and degradation pathway analysis through Quadrupole-time-of-flight-mass spectrometry. Bioresource technology. 2022 Apr; 349(?):126857. doi: 10.1016/j.biortech.2022.126857. [PMID: 35183727]
  • Edina Nemesházi, Gábor Sramkó, Levente Laczkó, Emese Balogh, Lajos Szatmári, Nóra Vili, Nikolett Ujhegyi, Bálint Üveges, Veronika Bókony. Novel genetic sex markers reveal unexpected lack of, and similar susceptibility to, sex reversal in free-living common toads in both natural and anthropogenic habitats. Molecular ecology. 2022 04; 31(7):2032-2043. doi: 10.1111/mec.16388. [PMID: 35146823]
  • Rebecca L Thompson, Jack Hu, Philip Custodio, Clint Dart, Jeffrey T Jensen. The use of serum segesterone acetate levels to assess adherence of trial participants with a contraceptive vaginal ring. Contraception. 2022 04; 108(?):61-64. doi: 10.1016/j.contraception.2021.12.004. [PMID: 34971614]
  • Leilei Bai, Xin Liu, Ke Hua, Linqi Tian, Changhui Wang, Helong Jiang. Microbial processing of autochthonous organic matter controls the biodegradation of 17α-ethinylestradiol in lake sediments under anoxic conditions. Environmental pollution (Barking, Essex : 1987). 2022 Mar; 296(?):118760. doi: 10.1016/j.envpol.2021.118760. [PMID: 34971738]
  • Teodora Pene Dumitrescu, Thomas J Greene, Samit R Joshi, Jianfeng Xu, Mark Johnson, Fiona Halliday, Laurie Butcher, Eric Zimmerman, Lindsey Webster, Theresa T Pham, Max Lataillade, Sherene Min. Lack of pharmacokinetic interaction between the HIV-1 maturation inhibitor GSK3640254 and combination oral contraceptives in healthy women. British journal of clinical pharmacology. 2022 02; 88(4):1704-1712. doi: 10.1111/bcp.15051. [PMID: 34427938]
  • Takafumi Shimada, Kouji Izumi, Hiroshi Kano, Suguru Kadomoto, Tomoyuki Makino, Renato Naito, Hiroaki Iwamoto, Hiroshi Yaegashi, Yoshifumi Kadono, Atsushi Mizokami. Ra-223 and Ethinylestradiol Combination Therapy in Castration-resistant Prostate Cancer. Anticancer research. 2022 Feb; 42(2):1065-1071. doi: 10.21873/anticanres.15568. [PMID: 35093908]
  • Tiziana Fidecicchi, Franca Fruzzetti, Luis Ignacio Lete Lasa, Joaquim Calaf. COVID-19, gender and estroprogestins, what do we know?. The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception. 2022 Feb; 27(1):67-74. doi: 10.1080/13625187.2021.2000959. [PMID: 34842025]
  • Karthik Lingineni, Ayyappa Chaturvedula, Brian Cicali, Rodrigo Cristofoletti, Thomas Wendl, Joachim Hoechel, Joshua D Brown, Valvanera Vozmediano, Stephan Schmidt. Determining the Exposure Threshold for Levonorgestrel Efficacy Using an Integrated Model Based Meta-Analysis Approach. Clinical pharmacology and therapeutics. 2022 02; 111(2):509-518. doi: 10.1002/cpt.2457. [PMID: 34674227]
  • Jun Wang, Xuan Li, Ming Gao, Xuefu Li, Lingchao Zhao, Shaoguo Ru. Polystyrene microplastics increase estrogenic effects of 17α-ethynylestradiol on male marine medaka (Oryzias melastigma). Chemosphere. 2022 Jan; 287(Pt 3):132312. doi: 10.1016/j.chemosphere.2021.132312. [PMID: 34563785]
  • María Del Carmen Ramírez-Montero, Leobardo Manuel Gómez-Oliván, Verónica Margarita Gutiérrez-Noya, José Manuel Orozco-Hernández, Hariz Islas-Flores, Gustavo Axel Elizalde-Velázquez, Nely SanJuan-Reyes, Marcela Galar-Martínez. Acute exposure to 17-α-ethinylestradiol disrupt the embryonic development and oxidative status of Danio rerio. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2022 Jan; 251(?):109199. doi: 10.1016/j.cbpc.2021.109199. [PMID: 34607023]
  • Madelon C Vonk, Alfredo Guillén-Del-Castillo, Michael Kreuter, Mandy Avis, Kristell Marzin, Salome R Mack, Sven Wind, Martina Gahlemann. A Drug-Drug Interaction Study to Investigate the Effect of Nintedanib on the Pharmacokinetics of Microgynon (Ethinylestradiol and Levonorgestrel) in Female Patients with Systemic Sclerosis-Associated Interstitial Lung Disease. European journal of drug metabolism and pharmacokinetics. 2022 Jan; 47(1):81-89. doi: 10.1007/s13318-021-00728-7. [PMID: 34664183]
  • Kristina Gemzell-Danielsson, Angelo Cagnacci, Nathalie Chabbert-Buffet, Jonathan Douxfils, Jean-Michel Foidart, Ali Kubba, Luis Ignacio Lete Lasa, Diana Mansour, Joseph Neulen, Jaoquim Neves, Fátima Palma, Thomas Römer, Robert Spaczy Ski, Vera Tóth. A novel estetrol-containing combined oral contraceptive: European expert panel review. Ceska gynekologie. 2022; 87(6):440-452. doi: 10.1080/ 13625187.2022.2093850. [PMID: 36543594]
  • Madhu Sanga, Subusola Vaughan, Julius Nangosyah, Veronika Scholz, Sergio Fonseca. Randomized, double-blind, two-way crossover bioequivalence and adhesion study, in healthy women, of a transdermal contraceptive patch with a newly sourced adhesive component at the end of shelf life vs. the EVRA patch at the beginning of shelf life. International journal of clinical pharmacology and therapeutics. 2022 Jan; 60(1):67-78. doi: 10.5414/cp204034. [PMID: 34779392]
  • Santiago Palacios, Enrico Colli, Pedro A Regidor. Metabolic and laboratory effects of a progestin-only pill containing drospirenone 4 mg in comparison to desogestrel 75 µg: a double-blind, double-dummy, prospective, randomised study. The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception. 2021 Dec; 26(6):454-461. doi: 10.1080/13625187.2021.1957094. [PMID: 34348526]
  • Wendy Ankrom, Deanne Jackson Rudd, Saijuan Zhang, Kerry L Fillgrove, Kezia N Gravesande, Randolph P Matthews, Darin Brimhall, S Aubrey Stoch, Marian N Iwamoto. A phase 1, open-label study to evaluate the drug interaction between islatravir (MK-8591) and the oral contraceptive levonorgestrel/ethinyl estradiol in healthy adult females. Journal of the International AIDS Society. 2021 12; 24(12):e25858. doi: 10.1002/jia2.25858. [PMID: 34935295]
  • Sang R Lee, Su Hee Jeong, Jun H Heo, Seong Lae Jo, Je-Won Ko, Hyo-Jung Kwun, Eui-Ju Hong. Dietary Intake of 17α-Ethinylestradiol Promotes HCC Progression in Humanized Male Mice Expressing Sex Hormone-Binding Globulin. International journal of molecular sciences. 2021 Nov; 22(22):. doi: 10.3390/ijms222212557. [PMID: 34830439]
  • Mingxiang Liao, Krzysztof G Jeziorski, Monika Tomaszewska-Kiecana, István Láng, Marek Jasiówka, Viera Skarbová, Piotr Centkowski, Rodryg Ramlau, Maria Górnaś, John Lee, Sarah Edwards, Jenn Habeck, Eileen Nash, Nikolay Grechko, Jim J Xiao. A phase 1, open-label, drug-drug interaction study of rucaparib with rosuvastatin and oral contraceptives in patients with advanced solid tumors. Cancer chemotherapy and pharmacology. 2021 11; 88(5):887-897. doi: 10.1007/s00280-021-04338-7. [PMID: 34370076]
  • Gerda Venter, Carien L van der Berg, Francois H van der Westhuizen, Elardus Erasmus. Health Status Is Affected, and Phase I/II Biotransformation Activity Altered in Young Women Using Oral Contraceptives Containing Drospirenone/Ethinyl Estradiol. International journal of environmental research and public health. 2021 10; 18(20):. doi: 10.3390/ijerph182010607. [PMID: 34682353]
  • Fernanda G Fleury, Luísa R F Guimarães, Elisa B Rezende, Tracy M M Martins, Cássia R S Caires, Fernanda C A Dos Santos, Sebastião R Taboga, Ana P da S Perez. Prenatal and pubertal exposure to 17α-ethinylestradiol cause morphological changes in the prostate of old gerbils. Cell biology international. 2021 Oct; 45(10):2074-2085. doi: 10.1002/cbin.11656. [PMID: 34189808]
  • Zsanett Mikó, Edina Nemesházi, Nikolett Ujhegyi, Viktória Verebélyi, János Ujszegi, Andrea Kásler, Réka Bertalan, Nóra Vili, Zoltán Gál, Orsolya I Hoffmann, Attila Hettyey, Veronika Bókony. Sex reversal and ontogeny under climate change and chemical pollution: are there interactions between the effects of elevated temperature and a xenoestrogen on early development in agile frogs?. Environmental pollution (Barking, Essex : 1987). 2021 Sep; 285(?):117464. doi: 10.1016/j.envpol.2021.117464. [PMID: 34380212]
  • James H Liu, Marlena Plagianos, David F Archer, James A Simon, Andrew M Kaunitz, Shelli Graham, Brian Bernick, Sebastian Mirkin. Segesterone acetate serum levels with a regression model of continuous use of the segesterone acetate/ethinyl estradiol contraceptive vaginal system. Contraception. 2021 09; 104(3):229-234. doi: 10.1016/j.contraception.2021.03.024. [PMID: 33785318]
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  • Fatemeh Alaei Faradonbeh, Ivone Igreja Sa, Hana Lastuvkova, Jolana Cermanova, Milos Hroch, Hana Faistova, Jaroslav Mokry, Zuzana Nova, Martin Uher, Petr Nachtigal, Petr Pavek, Stanislav Micuda. Metformin impairs bile acid homeostasis in ethinylestradiol-induced cholestasis in mice. Chemico-biological interactions. 2021 Aug; 345(?):109525. doi: 10.1016/j.cbi.2021.109525. [PMID: 34058177]
  • Albe Swanepoel, Janette Bester, Yolanda Kruger, Elmarie Davoren, Ilse du Preez. The effect of combined oral contraceptives containing drospirenone and ethinylestradiol on serum levels of amino acids and acylcarnitines. Metabolomics : Official journal of the Metabolomic Society. 2021 08; 17(9):75. doi: 10.1007/s11306-021-01825-z. [PMID: 34409503]
  • Zhao Tang, Ze-Hua Liu, Hao Wang, Zhi Dang, Yu Liu. A review of 17α-ethynylestradiol (EE2) in surface water across 32 countries: Sources, concentrations, and potential estrogenic effects. Journal of environmental management. 2021 Aug; 292(?):112804. doi: 10.1016/j.jenvman.2021.112804. [PMID: 34023789]
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