4,4-Dichlorobenzophenone (BioDeep_00000003962)

   


代谢物信息卡片


4,4?-Dichlorobenzophenone

化学式: C13H8Cl2O (249.9952)
中文名称: 4,4-二氯二苯甲酮, 4,4'-二氯二苯甲酮
谱图信息: 最多检出来源 Macaca mulatta(otcml) 43.28%

分子结构信息

SMILES: C1=CC(=CC=C1C(=O)C2=CC=C(C=C2)Cl)Cl
InChI: InChI=1S/C13H8Cl2O/c14-11-5-1-9(2-6-11)13(16)10-3-7-12(15)8-4-10/h1-8H

描述信息

CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 1068

同义名列表

5 个代谢物同义名

4,4-Dichlorobenzophenone; 4,4?-Dichlorobenzophenone; DBP; 4,4'-Dichlorobenzophenone; 4,4'-Dichlorobenzophenone



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 13 ALB, CLU, CRBN, CREBBP, CTNNB1, EP300, GRIN2B, HTT, MAPK8, PRKN, SBF1, TBP, TUBB2B
Peripheral membrane protein 2 CLU, CRBN
Endosome membrane 1 HTT
Endoplasmic reticulum membrane 2 GRIN2B, SBF1
Mitochondrion membrane 1 CLU
Nucleus 13 ALB, CLU, CRBN, CREBBP, CTNNB1, EP300, HTT, MAPK8, MYB, PRKN, SIN3A, TBP, TUBB2B
autophagosome 1 HTT
cytosol 11 ALB, CLU, CRBN, CREBBP, CTNNB1, EP300, HTT, MAPK8, MYB, PRKN, SBF1
dendrite 1 HTT
mitochondrial membrane 1 CLU
nuclear body 2 CREBBP, SBF1
centrosome 2 ALB, CTNNB1
nucleoplasm 8 CREBBP, CTNNB1, EP300, HTT, MAPK8, MYB, SIN3A, TBP
RNA polymerase II transcription regulator complex 1 MYB
Cell membrane 3 CTNNB1, GRIN2B, HTT
Cytoplasmic side 1 CLU
lamellipodium 1 CTNNB1
Multi-pass membrane protein 2 GRIN2B, HTT
Synapse 5 CLU, CTNNB1, HTT, MAPK8, TAC1
cell cortex 1 CTNNB1
cell junction 1 CTNNB1
cell surface 3 CLU, GRIN2B, SIRPA
glutamatergic synapse 1 CTNNB1
Golgi apparatus 4 ALB, CLU, HTT, PRKN
mitochondrial inner membrane 1 CLU
neuronal cell body 1 TAC1
presynaptic membrane 2 CTNNB1, HTT
Cytoplasm, cytosol 2 CLU, PRKN
Lysosome 1 GRIN2B
Presynapse 1 PRKN
plasma membrane 4 CTNNB1, GRIN2B, HTT, SIRPA
Membrane 6 CRBN, CTNNB1, GRIN2B, MYB, SBF1, SIRPA
axon 3 HTT, MAPK8, TAC1
basolateral plasma membrane 1 CTNNB1
extracellular exosome 4 ALB, CLU, CTNNB1, SIRPA
endoplasmic reticulum 4 ALB, CLU, HTT, PRKN
extracellular space 6 ALB, CLU, IL10, IL2, TAC1, TG
perinuclear region of cytoplasm 6 CLU, CRBN, CTNNB1, HTT, PRKN, SBF1
Schaffer collateral - CA1 synapse 2 CTNNB1, TUBB2B
adherens junction 1 CTNNB1
apicolateral plasma membrane 1 CTNNB1
bicellular tight junction 1 CTNNB1
mitochondrion 2 CLU, PRKN
protein-containing complex 5 ALB, CLU, CTNNB1, HTT, TBP
intracellular membrane-bounded organelle 1 CLU
postsynaptic density 2 GRIN2B, PRKN
Secreted 5 ALB, CLU, IL10, IL2, TG
extracellular region 6 ALB, CLU, IL10, IL2, TAC1, TG
Mitochondrion outer membrane 1 PRKN
mitochondrial outer membrane 1 PRKN
anchoring junction 1 ALB
transcription regulator complex 3 CREBBP, CTNNB1, EP300
Z disc 1 CTNNB1
beta-catenin destruction complex 1 CTNNB1
microtubule cytoskeleton 1 TUBB2B
nucleolus 1 SIN3A
Wnt signalosome 1 CTNNB1
Early endosome 1 HTT
apical part of cell 1 CTNNB1
cell-cell junction 1 CTNNB1
postsynaptic membrane 3 CTNNB1, GRIN2B, HTT
Cytoplasm, perinuclear region 2 CLU, SBF1
Membrane raft 1 HTT
Cell junction, focal adhesion 1 HTT
Cytoplasm, cytoskeleton 3 CTNNB1, GRIN2B, TUBB2B
focal adhesion 2 CTNNB1, HTT
microtubule 1 TUBB2B
Cell junction, adherens junction 1 CTNNB1
flotillin complex 1 CTNNB1
collagen-containing extracellular matrix 1 CLU
fascia adherens 1 CTNNB1
lateral plasma membrane 1 CTNNB1
nuclear speck 1 PRKN
Postsynaptic cell membrane 1 GRIN2B
Late endosome 2 GRIN2B, HTT
Cell projection, neuron projection 3 HTT, PRKN, SBF1
neuron projection 4 GRIN2B, HTT, PRKN, SBF1
ciliary basal body 1 ALB
chromatin 4 CREBBP, EP300, SIN3A, TBP
cell periphery 1 CTNNB1
mitotic spindle 1 TUBB2B
Chromosome 1 EP300
cytoskeleton 1 GRIN2B
Cytoplasm, cytoskeleton, cilium basal body 1 CTNNB1
centriole 2 ALB, HTT
Nucleus, nucleolus 1 SIN3A
spindle pole 2 ALB, CTNNB1
blood microparticle 2 ALB, CLU
postsynaptic density, intracellular component 1 CTNNB1
microvillus membrane 1 CTNNB1
intercellular bridge 1 TUBB2B
Endomembrane system 2 CTNNB1, HTT
female germ cell nucleus 1 TBP
Cytoplasmic vesicle membrane 1 HTT
Cell projection, dendrite 1 GRIN2B
tertiary granule membrane 1 SIRPA
euchromatin 2 CTNNB1, TBP
ubiquitin ligase complex 1 PRKN
[Isoform 4]: Cytoplasm 1 CLU
synaptic membrane 1 GRIN2B
Microsome 1 CLU
endoplasmic reticulum lumen 1 ALB
nuclear matrix 1 MYB
transcription repressor complex 1 SIN3A
male germ cell nucleus 1 TBP
transcription factor TFIID complex 1 TBP
platelet alpha granule lumen 2 ALB, CLU
kinetochore 1 SIN3A
histone deacetylase complex 1 SIN3A
beta-catenin-TCF complex 1 CTNNB1
postsynaptic density membrane 1 GRIN2B
aggresome 1 PRKN
presynaptic active zone cytoplasmic component 1 CTNNB1
histone acetyltransferase complex 2 CREBBP, EP300
Sin3-type complex 1 SIN3A
protein-DNA complex 2 CTNNB1, EP300
ficolin-1-rich granule membrane 1 SIRPA
NMDA selective glutamate receptor complex 1 GRIN2B
apical dendrite 1 CLU
basal dendrite 1 MAPK8
female pronucleus 1 TBP
male pronucleus 1 TBP
dopaminergic synapse 1 PRKN
Lewy body 1 PRKN
Parkin-FBXW7-Cul1 ubiquitin ligase complex 1 PRKN
postsynaptic cytosol 1 HTT
catenin complex 1 CTNNB1
presynaptic cytosol 1 HTT
spherical high-density lipoprotein particle 1 CLU
[Isoform 1]: Secreted 1 CLU
inclusion body 1 HTT
neurofibrillary tangle 1 CLU
Cytoplasmic vesicle, secretory vesicle, chromaffin granule 1 CLU
chromaffin granule 1 CLU
[Isoform 6]: Cytoplasm 1 CLU
perinuclear endoplasmic reticulum lumen 1 CLU
beta-catenin-TCF7L2 complex 1 CTNNB1
RNA polymerase transcription factor SL1 complex 1 TBP
transcription factor TFIIA complex 1 TBP
serotonergic synapse 1 HTT
beta-catenin-ICAT complex 1 CTNNB1
Scrib-APC-beta-catenin complex 1 CTNNB1
[Huntingtin]: Cytoplasm 1 HTT
[Huntingtin, myristoylated N-terminal fragment]: Cytoplasmic vesicle, autophagosome 1 HTT
Cul4A-RING E3 ubiquitin ligase complex 1 CRBN
ciliary transition fiber 1 ALB


文献列表

  • Ge Yin, Ioannis Athanassiadis, Åke Bergman, Yihui Zhou, Yanling Qiu, Lillemor Asplund. A refined method for analysis of 4,4'-dicofol and 4,4'-dichlorobenzophenone. Environmental science and pollution research international. 2017 May; 24(15):13307-13314. doi: 10.1007/s11356-017-8956-y. [PMID: 28386885]
  • Anette Thiel, Sabine Guth, Sonja Böhm, Gerhard Eisenbrand. Dicofol degradation to p,p'-dichlorobenzophenone - a potential antiandrogen. Toxicology. 2011 Apr; 282(3):88-93. doi: 10.1016/j.tox.2011.01.016. [PMID: 21291947]
  • V W Burse, P C McClure, M P Korver, S L Head, L L Needham. Potential compounds for monitoring method performance in the determination of selected organochlorine pesticides and polychlorinated biphenyls in human serum. Journal of analytical toxicology. 1990 May; 14(3):143-5. doi: 10.1093/jat/14.3.143. [PMID: 2165198]