Vincristine (BioDeep_00000000390)
Secondary id: BioDeep_00000398852
human metabolite PANOMIX_OTCML-2023 blood metabolite Chemicals and Drugs natural product
代谢物信息卡片
methyl (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-(methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.0^{4,12}.0^{5,10}]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraene-10-carboxylate
化学式: C46H56N4O10 (824.3996)
中文名称: 长春新碱
谱图信息:
最多检出来源 Viridiplantae(plant) 13.02%
分子结构信息
SMILES: CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O
InChI: InChI=1S/C46H56N4O10/c1-7-42(55)22-28-23-45(40(53)58-5,36-30(14-18-48(24-28)25-42)29-12-9-10-13-33(29)47-36)32-20-31-34(21-35(32)57-4)50(26-51)38-44(31)16-19-49-17-11-15-43(8-2,37(44)49)39(60-27(3)52)46(38,56)41(54)59-6/h9-13,15,20-21,26,28,37-39,47,55-56H,7-8,14,16-19,22-25H2,1-6H3
描述信息
Vincristine appears as a white crystalline solid. Melting point 218 °C. Used as an antineoplastic.
Vincristine is a vinca alkaloid with formula C46H56N4O10 found in the Madagascar periwinkle, Catharanthus roseus. It is used (commonly as the corresponding sulfate salt)as a chemotherapy drug for the treatment of leukaemia, lymphoma, myeloma, breast cancer and head and neck cancer. It has a role as a tubulin modulator, a microtubule-destabilising agent, a plant metabolite, an antineoplastic agent and a drug. It is a methyl ester, an acetate ester, a tertiary alcohol, a member of formamides, an organic heteropentacyclic compound, an organic heterotetracyclic compound, a tertiary amino compound and a vinca alkaloid. It is a conjugate base of a vincristine(2+). It derives from a hydride of a vincaleukoblastine.
Vincristine is a natural product found in Ophioparma ventosa, Cunila, and other organisms with data available.
Vincristine is a natural alkaloid isolated from the plant Vinca rosea Linn. Vincristine binds irreversibly to microtubules and spindle proteins in S phase of the cell cycle and interferes with the formation of the mitotic spindle, thereby arresting tumor cells in metaphase. This agent also depolymerizes microtubules and may also interfere with amino acid, cyclic AMP, and glutathione metabolism; calmodulin-dependent Ca++ -transport ATPase activity; cellular respiration; and nucleic acid and lipid biosynthesis. (NCI04)
Vincristine is only found in individuals that have used or taken this drug. It is an antitumor alkaloid isolated from Vinca Rosea. (Merck, 11th ed.) The antitumor activity of Vincristine is thought to be due primarily to inhibition of mitosis at metaphase through its interaction with tubulin. Like other vinca alkaloids, Vincristine may also interfere with: 1) amino acid, cyclic AMP, and glutathione metabolism, 2) calmodulin-dependent Ca2+-transport ATPase activity, 3) cellular respiration, and 4) nucleic acid and lipid biosynthesis. Vincristine is indicated for the treatment of acute leukaemia, malignant lymphoma, Hodgkins disease, acute erythraemia, and acute panmyelosis. Vincristine sulfate is often chosen as part of polychemotherapy because of lack of significant bone marrow suppression (at recommended doses) and of unique clinical toxicity (neuropathy).
An antitumor alkaloid isolated from VINCA ROSEA. (Merck, 11th ed.)
See also: Vincristine Sulfate (active moiety of).
Vincristine is only found in individuals that have used or taken this drug. It is an antitumor alkaloid isolated from Vinca Rosea. (Merck, 11th ed.)The antitumor activity of Vincristine is thought to be due primarily to inhibition of mitosis at metaphase through its interaction with tubulin. Like other vinca alkaloids, Vincristine may also interfere with: 1) amino acid, cyclic AMP, and glutathione metabolism, 2) calmodulin-dependent Ca2+-transport ATPase activity, 3) cellular respiration, and 4) nucleic acid and lipid biosynthesis.
A vinca alkaloid with formula C46H56N4O10 found in the Madagascar periwinkle, Catharanthus roseus. It is used (commonly as the corresponding sulfate salt)as a chemotherapy drug for the treatment of leukaemia, lymphoma, myeloma, breast cancer and head and neck cancer.
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01C - Plant alkaloids and other natural products > L01CA - Vinca alkaloids and analogues
C274 - Antineoplastic Agent > C1931 - Antineoplastic Plant Product > C932 - Vinca Alkaloid Compound
C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C273 - Antimitotic Agent
D050258 - Mitosis Modulators > D050256 - Antimitotic Agents > D050257 - Tubulin Modulators
D000970 - Antineoplastic Agents > D050256 - Antimitotic Agents
D000970 - Antineoplastic Agents > D014748 - Vinca Alkaloids
C1907 - Drug, Natural Product
同义名列表
61 个代谢物同义名
methyl (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-(methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.0^{4,12}.0^{5,10}]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraene-10-carboxylate; methyl (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-(methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.0⁴,¹².0⁵,¹⁰]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.0¹,⁹.0²,⁷.0¹⁶,¹⁹]nonadeca-2,4,6,13-tetraene-10-carboxylate; methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate; Vincaleukoblastine, 22-oxo- 22-Oxovincaleukoblastine; Vincasar (1:1 sulfate salt); OGWKCGZFUXNPDA-XQKSVPLYSA-N; Vincaleukoblastine, 22-oxo-; Vincristine (Leurocristine); Vincrex (1:1 sulfate salt); Oncovin (1:1 sulfate salt); 22-oxo-vincaleukoblastine; Vincristinum (INN-Latin); Vincristinum [INN-Latin]; 22-Oxovincaleukoblastine; 22-Oxovincaleukoblastin; oncovin (brand name); Sulfate, Vincristine; Vincristine Sulfate; Vincristina [DCIT]; Vincristin Bristol; Z-D-Val-lys(Z)-OH; Vincristine (INN); Vincristin medac; (+)-Vincristine; rel-Vincristine; Indole alkaloid; UNII-5J49Q6B70F; Tox21_112067_1; Tecnocris (TN); PFS, Vincasar; Leurocristine; Vincasar PFS; Tox21_112067; Vincristinum; NCI60_026703; Kyocristine; leucristine; cellcristin; Onkocristin; CAS-57-22-7; Vincristina; Vincristine; Vincrystine; vincristin; Vinkristin; Vincrstine; Farmistin; Tecnocris; Vincrisul; Vincasar; Oncovine; Oncovin; L01CA02; Citomid; Oncotcs; Vintec; LCR; VIN; VCR; Vincristine (free base); Vincristine
数据库引用编号
28 个数据库交叉引用编号
- ChEBI: CHEBI:28445
- KEGG: C07204
- KEGGdrug: D08679
- PubChem: 5388993
- PubChem: 5978
- PubChem: 3717450
- HMDB: HMDB0014681
- Metlin: METLIN602
- DrugBank: DB00541
- ChEMBL: CHEMBL499458
- ChEMBL: CHEMBL90555
- ChEMBL: CHEMBL1740907
- Wikipedia: Vincristine
- MeSH: Vincristine
- MetaCyc: CPD-19894
- KNApSAcK: C00001783
- chemspider: 5758
- CAS: 1217704-92-1
- CAS: 132142-73-5
- CAS: 57-22-7
- medchemexpress: HY-N0488A
- PMhub: MS000001491
- MetaboLights: MTBLC28445
- PubChem: 9413
- 3DMET: B02110
- NIKKAJI: J10.132J
- KNApSAcK: 28445
- LOTUS: LTS0189111
分类词条
相关代谢途径
Reactome(0)
代谢反应
4 个相关的代谢反应过程信息。
Reactome(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(2)
- vindoline, vindorosine and vinblastine biosynthesis:
catharanthine + hydrogen peroxide + vindoline ⟶ α-3',4'-anhydrovinblastine radical + H2O - vindoline, vindorosine and vinblastine biosynthesis:
catharanthine + hydrogen peroxide + vindoline ⟶ α-3',4'-anhydrovinblastine radical + H2O
COVID-19 Disease Map(0)
PathBank(1)
- Vincristine Action Pathway:
Adenosine triphosphate + Vincristine + Water ⟶ Adenosine diphosphate + Phosphate + Vincristine
PharmGKB(0)
23 个相关的物种来源信息
- 4056 - Apocynaceae: LTS0189111
- 4057 - Catharanthus: LTS0189111
- 4058 - Catharanthus roseus:
- 4058 - Catharanthus roseus: 10.1002/PCA.575
- 4058 - Catharanthus roseus: 10.1016/0021-9673(94)80146-0
- 4058 - Catharanthus roseus: 10.1016/S0021-9673(96)00614-0
- 4058 - Catharanthus roseus: 10.1055/S-2006-962777
- 4058 - Catharanthus roseus: 10.1080/01483918408073937
- 4058 - Catharanthus roseus: 10.1080/10826079708010966
- 4058 - Catharanthus roseus: 10.1081/JLC-100101476
- 4058 - Catharanthus roseus: 10.1248/CPB.50.1294
- 4058 - Catharanthus roseus: LTS0189111
- 392618 - Cunila: 10.1007/S00299-018-2303-8
- 392618 - Cunila: LTS0189111
- 2759 - Eukaryota: LTS0189111
- 9606 - Homo sapiens: -
- 4136 - Lamiaceae: LTS0189111
- 3398 - Magnoliopsida: LTS0189111
- 35493 - Streptophyta: LTS0189111
- 58023 - Tracheophyta: LTS0189111
- 60093 - Vinca minor: 10.1002/PCA.852
- 33090 - Viridiplantae: LTS0189111
- 33090 - 长春花: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ian Stoppa, Chiara Dianzani, Nausicaa Clemente, Annalisa Bozza, Valentina Bordano, Sara Garelli, Luigi Cangemi, Umberto Dianzani, Luigi Battaglia. Alendronate-Grafted Nanoemulsions for Bone-Targeted Vincristine Delivery: Preliminary Studies on Cell and Animal Models.
Biomolecules.
2024 Feb; 14(2):. doi:
10.3390/biom14020238. [PMID: 38397475] - Jin-Yu Ning, Bo Ma, Jing-Yi Huang, Liang Han, Yan-Hua Shao, Feng-Yun Wang. Integrated network pharmacology and metabolomics reveal the action mechanisms of vincristine combined with celastrol against colon cancer.
Journal of pharmaceutical and biomedical analysis.
2024 Feb; 239(?):115883. doi:
10.1016/j.jpba.2023.115883. [PMID: 38044218] - Mohammad Rasoul Samandari-Bahraseman, Ahmad Ismaili, Saeed Esmaeili-Mahani, Esmaeil Ebrahimie, Evelin Loit. Bunium Persicum Seeds Extract in Combination with Vincristine Mediates Apoptosis in MCF-7 Cells through Regulation of Involved Genes and Proteins Expression.
Anti-cancer agents in medicinal chemistry.
2023 Nov; ?(?):. doi:
10.2174/0118715206277444231124051035. [PMID: 38038013] - Rahul Shukla, Ajit Singh, Kamalinder K Singh. Vincristine-based nanoformulations: a preclinical and clinical studies overview.
Drug delivery and translational research.
2023 Aug; ?(?):. doi:
10.1007/s13346-023-01389-6. [PMID: 37552393] - James M Kelvin, Madison L Chimenti, Dan Y Zhang, Evelyn K Williams, Samuel G Moore, Gabrielle M Humber, Travon A Baxter, Lacey A Birnbaum, Min Qui, Henry Zecca, Aashis Thapa, Juhi Jain, Nathan T Jui, Xiaodong Wang, Haian Fu, Yuhong Du, Melissa L Kemp, Wilbur A Lam, Douglas K Graham, Deborah DeRyckere, Erik C Dreaden. Development of constitutively synergistic nanoformulations to enhance chemosensitivity in T-cell leukemia.
Journal of controlled release : official journal of the Controlled Release Society.
2023 Aug; ?(?):. doi:
10.1016/j.jconrel.2023.07.045. [PMID: 37543290] - Katalin Nagy, Éva Darkó, Gabriella Szalai, Tibor Janda, Zsuzsa Jókai, Márta Ladányi, Mohamed Ramadan Rady, Mihály Dernovics. UPLC-ESI-QTOF-MS assisted targeted metabolomics to study the enrichment of vinca alkaloids and related metabolites in Catharanthus roseus plants grown under controlled LED environment.
Journal of pharmaceutical and biomedical analysis.
2023 Jul; 235(?):115611. doi:
10.1016/j.jpba.2023.115611. [PMID: 37542828] - Hossam S El-Beltagi, Salwa M El-Sayed, Ahmed N Abdelhamid, Karim M Hassan, Walaa A Elshalakany, Mona Ibrahim Nossier, Nadiyah M Alabdallah, Nadi Awad Al-Harbi, Salem Mesfir Al-Qahtani, Doaa Bahaa Eldin Darwish, Zahid Khorshid Abbas, Hemmat A Ibrahim. Potentiating Biosynthesis of Alkaloids and Polyphenolic Substances in Catharanthus roseus Plant Using ĸ-Carrageenan.
Molecules (Basel, Switzerland).
2023 Apr; 28(8):. doi:
10.3390/molecules28083642. [PMID: 37110876] - Suneel Kumar, Nitin Swamy, Hardeep Singh Tuli, Seema Rani, Abhijeet Garg, Deepa Mishra, Hadi Sajid Abdulabbas, Sardul Singh Sandhu. Myricetin: a potential plant-derived anticancer bioactive compound-an updated overview.
Naunyn-Schmiedeberg's archives of pharmacology.
2023 Apr; ?(?):. doi:
10.1007/s00210-023-02479-5. [PMID: 37083713] - Manish L Raorane, Christina Manz, Sarah Hildebrandt, Marion Mielke, Marc Thieme, Judith Keller, Mirko Bunzel, Peter Nick. Cell type matters: competence for alkaloid metabolism differs in two seed-derived cell strains of Catharanthus roseus.
Protoplasma.
2023 Mar; 260(2):349-369. doi:
10.1007/s00709-022-01781-y. [PMID: 35697946] - Yuanjian Yang, Liuyu Ding, Ying Zhou, Zizheng Guo, Rongmin Yu, Jianhua Zhu. Establishment of recombinant Catharanthus roseus stem cells stably overexpressing ORCA4 for terpenoid indole alkaloids biosynthesis.
Plant physiology and biochemistry : PPB.
2023 Feb; 196(?):783-792. doi:
10.1016/j.plaphy.2023.02.039. [PMID: 36848864] - Fei Wang, Luo Lu, HuiJuan Chen, Yanhua Yue, Yanting Sun, Feng Yan, Bai He, Rongrong Lin, Weiying Gu. Altered serum lipid levels are associated with prognosis of diffuse large B cell lymphoma and influenced by utility of rituximab.
Annals of hematology.
2023 Feb; 102(2):393-402. doi:
10.1007/s00277-023-05092-x. [PMID: 36670246] - Purin Candra Purnama, Leonardo Castellanos Hernandez, Robert Verpoorte. Do Fungicides Affect Alkaloid Production in Catharanthus roseus (L.) G. Don. Seedlings?.
Molecules (Basel, Switzerland).
2023 Feb; 28(3):. doi:
10.3390/molecules28031405. [PMID: 36771067] - Tomasz Kostrzewa, Izabela Nowak, Agnieszka Feliczak-Guzik, Joanna Drzeżdżon, Dagmara Jacewicz, Magdalena Górska-Ponikowska, Alicja Kuban-Jankowska. Encapsulated Oxovanadium(IV) and Dioxovanadium(V) Complexes into Solid Lipid Nanoparticles Increase Cytotoxicity Against MDA-MB-231 Cell Line.
International journal of nanomedicine.
2023; 18(?):2507-2523. doi:
10.2147/ijn.s403689. [PMID: 37197025] - Mengwei Xu, Rui Peng, Qing Min, Siwen Hui, Xin Chen, Guang Yang, Shuanglin Qin. Bisindole natural products: A vital source for the development of new anticancer drugs.
European journal of medicinal chemistry.
2022 Dec; 243(?):114748. doi:
10.1016/j.ejmech.2022.114748. [PMID: 36170798] - Fei Fei, Mingfeng Zhang, Somayeh S Tarighat, Eun Ji Joo, Lu Yang, Nora Heisterkamp. Galectin-1 and Galectin-3 in B-Cell Precursor Acute Lymphoblastic Leukemia.
International journal of molecular sciences.
2022 Nov; 23(22):. doi:
10.3390/ijms232214359. [PMID: 36430839] - Jawad Khan, Gowhar Ali, Asma Khurshid, Aamer Saeed, Sajjad Ahmad, Najeeb Ullah, Ashrafullah Khan, Robert D Sewell, Muhammad Zakria. Mechanistic efficacy assessment of selected novel methanimine derivatives against vincristine induced Neuropathy: In-vivo, Ex-vivo and In-silico correlates.
International immunopharmacology.
2022 Nov; 112(?):109246. doi:
10.1016/j.intimp.2022.109246. [PMID: 36116153] - Fanfan Li, Stephen Bordeleau, Kyung Hee Kim, Jonathan Turcotte, Benjamin Davis, Lan Liu, Stéphane Bayen, Vincenzo De Luca, Mehran Dastmalchi. A lesion-mimic mutant of Catharanthus roseus accumulates the opioid agonist, akuammicine.
Phytochemistry.
2022 Nov; 203(?):113422. doi:
10.1016/j.phytochem.2022.113422. [PMID: 36055422] - Adedoyin O Adefisan, Solomon E Owumi, Kehinde O Soetan, Oluwatosin A Adaramoye. Chloroform extract of Calliandra portoricensis inhibits tumourigenic effect of N-methyl-N-nitrosourea and benzo(a)pyrene in breast experimental cancer.
Drug and chemical toxicology.
2022 Nov; 45(6):2424-2438. doi:
10.1080/01480545.2021.1957556. [PMID: 34325589] - M Ahmadzadeh, A H Keshtkar, K Moslemkhany, M Ahmadzadeh. Effect of the plant probiotic bacteria on terpenoid indole alkaloid biosynthesis pathway gene expression profiling, vinblastine and vincristine content in the root of Catharanthus roseus.
Molecular biology reports.
2022 Nov; 49(11):10357-10365. doi:
10.1007/s11033-022-07841-z. [PMID: 36097118] - Narges Soltani, Farhad Nazarian Firouzabadi, Alireza Shafeinia, Masoud Shirali, Ayeh Sadat Sadr. De Novo transcriptome assembly and differential expression analysis of catharanthus roseus in response to salicylic acid.
Scientific reports.
2022 10; 12(1):17803. doi:
10.1038/s41598-022-20314-4. [PMID: 36280677] - A Mujib, Samar Fatima, Moien Qadir Malik. Cryo-derived plants through embryogenesis showed same levels of vinblastine and vincristine (anticancer) in Catharanthus roseus and had normal genome size.
Scientific reports.
2022 10; 12(1):16635. doi:
10.1038/s41598-022-20993-z. [PMID: 36198853] - Vivek Jain, Ashutosh Pareek, Yashumati Ratan Bhardwaj, Saurabh Kumar Sinha, Madan Mohan Gupta, Nirmal Singh. Punicalagin and ellagic acid containing Punica granatum L. fruit rind extract prevents vincristine-induced neuropathic pain in rats: an in silico and in vivo evidence of GABAergic action and cytokine inhibition.
Nutritional neuroscience.
2022 Oct; 25(10):2149-2166. doi:
10.1080/1028415x.2021.1954293. [PMID: 34369317] - A Mujib, Samar Fatima, Moien Qadir Malik. Gamma ray-induced tissue responses and improved secondary metabolites accumulation in Catharanthus roseus.
Applied microbiology and biotechnology.
2022 Sep; 106(18):6109-6123. doi:
10.1007/s00253-022-12122-7. [PMID: 35962802] - Irene Canales Ruiz, Maurizio Martelli, Laurie H Sehn, Umberto Vitolo, Tina G Nielsen, Gila Sellam, Alessia Bottos, Dirk Klingbiel, Lale Kostakoglu. Baseline Total Metabolic Tumor Volume is Prognostic for Refractoriness to Immunochemotherapy in DLBCL: Results From GOYA.
Clinical lymphoma, myeloma & leukemia.
2022 Aug; 22(8):e804-e814. doi:
10.1016/j.clml.2022.04.010. [PMID: 35595618] - Naomi Shimizu, Daiji Ngayama, Yasuhiro Watanabe, Takashi Yamaguchi, Shoko Nakamura, Masahiro Ohira, Atsuhito Saiki, Hiroki Onda, Shuhei Yamaoka, Kazuki Abe, Chiaki Nakaseko, Ichiro Tatsuno. Rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone (R-CHOP) therapy increases carotid intima-media thickness and plaque score with von Willebrand factor activity elevation in patients with malignant lymphoma.
Journal of chemotherapy (Florence, Italy).
2022 Jul; 34(4):258-263. doi:
10.1080/1120009x.2021.1988202. [PMID: 34661507] - Shaghufta Perveen, Naila Safdar, Azra Yasmin, Yamin Bibi. DAT and PRX1 gene expression modulates vincristine production in Catharanthus roseus L. propagates using Cu, Fe and Zn nano structures.
Plant science : an international journal of experimental plant biology.
2022 Jul; 320(?):111264. doi:
10.1016/j.plantsci.2022.111264. [PMID: 35643614] - Murali M Chintagumpala, Elizabeth J Perlman, Brett Tornwall, Yueh-Yun Chi, Yeonil Kim, Fredric A Hoffer, John A Kalapurakal, Anne B Warwick, Robert C Shamberger, Geetika Khanna, Thomas E Hamilton, Kenneth W Gow, Arnold C Paulino, Eric J Gratias, Elizabeth A Mullen, James I Geller, Conrad V Fernandez, Michael L Ritchey, Paul E Grundy, Jeffrey S Dome, Peter F Ehrlich. Outcomes based on histopathologic response to preoperative chemotherapy in children with bilateral Wilms tumor: A prospective study (COG AREN0534).
Cancer.
2022 07; 128(13):2493-2503. doi:
10.1002/cncr.34219. [PMID: 35383900] - Hasan Nassereldine, Razan Mohty, Hussein Awada, Iman Abou Dalle, Jean El-Cheikh, Ali Bazarbachi. Mantle cell lymphoma negative for t(11,14) involving the kidneys: a case report.
Journal of medical case reports.
2022 Jun; 16(1):254. doi:
10.1186/s13256-022-03470-z. [PMID: 35768844] - Yuta Shinohara, Mohamed Elbadawy, Megumi Yamanaka, Haru Yamamoto, Amira Abugomaa, Tatsuya Usui, Kazuaki Sasaki. Effect of the liquid form of traditional Chinese medicine, Hozen-S, on gastric motility in dogs.
The Journal of veterinary medical science.
2022 Jun; 84(6):841-846. doi:
10.1292/jvms.21-0644. [PMID: 35473800] - L T van der Heijden, A Gebretensae, B Thijssen, L van Andel, A L Nijstad, Y Wang, H Rosing, A D R Huitema, J H Beijnen. A highly sensitive bioanalytical method for the quantification of vinblastine, vincristine, vinorelbine and 4-O-deacetylvinorelbine in human plasma using LC-MS/MS.
Journal of pharmaceutical and biomedical analysis.
2022 Jun; 215(?):114772. doi:
10.1016/j.jpba.2022.114772. [PMID: 35462284] - Hong-Li Zhang, Adina Uticul, Xiao-Wei Xu, Yu-Wei Shi. [Correlation between Serum miR-34a Level and Thrombocytopenia after Chemotherapy in Patients with Diffuse Large B-Cell Lymphoma].
Zhongguo shi yan xue ye xue za zhi.
2022 Jun; 30(3):784-789. doi:
10.19746/j.cnki.issn.1009-2137.2022.03.020. [PMID: 35680806] - Marius Mbiantcha, Raymond Guy Feuya Tchouya, William Nana Yousseu, Donatien Albert Atsamo, Hibrahim Foundikou, Jacques Lebibi, Franklin Gamo Zemo. Scyphocephalione A isolated from the stem bark of Scyphocephalium ochocoa (Myristicaceae) attenuate acute and chronic pain through the antiinflammatory activity.
Inflammopharmacology.
2022 Jun; 30(3):991-1003. doi:
10.1007/s10787-022-00966-4. [PMID: 35347522] - William Mifsud, Rhoikos Furtwängler, Christian Vokuhl, Ellen D'Hooghe, Kathy Pritchard-Jones, Norbert Graf, Gordan M Vujanić. Treatment of patients with stage I focal anaplastic and diffuse anaplastic Wilms tumour: A report from the SIOP-WT-2001 GPOH and UK-CCLG studies.
European journal of cancer (Oxford, England : 1990).
2022 05; 166(?):1-7. doi:
10.1016/j.ejca.2022.01.036. [PMID: 35255331] - Mohammed Sedeeq, Ahmed Maklad, Taush Dutta, Zikai Feng, Richard Wilson, Nuri Gueven, Iman Azimi. T-Type Calcium Channel Inhibitors Induce Apoptosis in Medulloblastoma Cells Associated with Altered Metabolic Activity.
Molecular neurobiology.
2022 May; 59(5):2932-2945. doi:
10.1007/s12035-022-02771-0. [PMID: 35243582] - Mohamed Osman Azzazi, Hany Mohamed Hegab, Amro Mohamed Sedky El-Ghammaz, Heba Mohamed Saber, Youssef Adel Afifi. Impact of serum soluble CD155 level at diagnosis on interim response to CHOP with or without rituximab in diffuse large B cell lymphoma.
Clinical and experimental medicine.
2022 May; 22(2):173-181. doi:
10.1007/s10238-021-00741-9. [PMID: 34216302] - Kanchan Birat, Tariq Omar Siddiqi, Showkat Rasool Mir, Junaid Aslan, Rakhi Bansal, Washim Khan, Rikeshwer Prasad Dewangan, Bibhu Prasad Panda. Enhancement of vincristine under in vitro culture of Catharanthus roseus supplemented with Alternaria sesami endophytic fungal extract as a biotic elicitor.
International microbiology : the official journal of the Spanish Society for Microbiology.
2022 May; 25(2):275-284. doi:
10.1007/s10123-021-00213-w. [PMID: 34622356] - Kei Saito, Satoshi Ichikawa, Shunsuke Hatta, Yuna Katsuoka, Hideo Harigae, Tohru Izumi. Vincristine therapy for severe and refractory immune thrombocytopenia following COVID-19 vaccination.
Annals of hematology.
2022 04; 101(4):885-887. doi:
10.1007/s00277-021-04666-x. [PMID: 34599382] - Vyoma Mistry, Siddhi Darji, Pragya Tiwari, Abhishek Sharma. Engineering Catharanthus roseus monoterpenoid indole alkaloid pathway in yeast.
Applied microbiology and biotechnology.
2022 Apr; 106(7):2337-2347. doi:
10.1007/s00253-022-11883-5. [PMID: 35333954] - Judith Trotman, Andrew R Pettitt. Is it time for PET-guided therapy in follicular lymphoma?.
Blood.
2022 03; 139(11):1631-1641. doi:
10.1182/blood.2020008243. [PMID: 34260714] - Amira M Elshamy, Ola M Salem, Mohamed A E Safa, Ramez A E Barhoma, Eman F Eltabaa, Amany M Shalaby, Mohamed A Alabiad, Heba M Arakeeb, Hoda A Mohamed. Possible protective effects of CO Q10 against vincristine-induced peripheral neuropathy: Targeting oxidative stress, inflammation, and sarmoptosis.
Journal of biochemical and molecular toxicology.
2022 Mar; 36(3):e22976. doi:
10.1002/jbt.22976. [PMID: 34939713] - Alissa Groenendijk, Harm van Tinteren, Yilin Jiang, Ronald R de Krijger, Gordan M Vujanic, Jan Godzinski, Christian Rübe, Jens-Peter Schenk, Carlo Morosi, Kathy Pritchard-Jones, Reem Al-Saadi, Sucheta J Vaidya, Arnauld C Verschuur, Gema L Ramírez-Villar, Norbert Graf, Beatriz de Camargo, Jarno Drost, Daniela Perotti, Marry M van den Heuvel-Eibrink, Jesper Brok, Filippo Spreafico, Annelies M C Mavinkurve-Groothuis. Outcome of SIOP patients with low- or intermediate-risk Wilms tumour relapsing after initial vincristine and actinomycin-D therapy only - the SIOP 93-01 and 2001 protocols.
European journal of cancer (Oxford, England : 1990).
2022 03; 163(?):88-97. doi:
10.1016/j.ejca.2021.12.014. [PMID: 35042071] - Ivan Dlouhy, Kennosuke Karube, Anna Enjuanes, Itziar Salaverria, Ferran Nadeu, Juan Enric Ramis-Zaldivar, Juan G Valero, Alfredo Rivas-Delgado, Laura Magnano, David Martin-García, Patricia Pérez-Galán, Guillem Clot, Jordina Rovira, Pedro Jares, Olga Balagué, Eva Giné, Pablo Mozas, Javier Briones, Juan-Manuel Sancho, Antonio Salar, Santiago Mercadal, Miguel Alcoceba, Alexandra Valera, Elías Campo, Armando López-Guillermo. Revised International Prognostic Index and genetic alterations are associated with early failure to R-CHOP in patients with diffuse large B-cell lymphoma.
British journal of haematology.
2022 02; 196(3):589-598. doi:
10.1111/bjh.17858. [PMID: 34632572] - Megan Fleming, Ying Huang, Emily Dotson, David A Bond, John Reneau, Narendranath Epperla, Lapo Alinari, Jonathan Brammer, Beth A Christian, Robert A Baiocchi, Kami Maddocks, Yazeed Sawalha. Feasibility of high-dose methotrexate administered on day 1 of (R)CHOP in aggressive non-Hodgkin lymphomas.
Blood advances.
2022 01; 6(2):460-472. doi:
10.1182/bloodadvances.2021005999. [PMID: 34788387] - Prakriti Roy, Sophie E van Peer, Martin M de Witte, Godelieve A M Tytgat, Henrike E Karim-Kos, Martine van Grotel, Cees P van de Ven, Annelies M C Mavinkurve-Groothuis, Johannes H M Merks, Roland P Kuiper, Janna A Hol, Geert O R Janssens, Ronald R de Krijger, Marjolijn C J Jongmans, Jarno Drost, Alida F W van der Steeg, Annemieke S Littooij, Marc H W A Wijnen, Harm van Tinteren, Marry M van den Heuvel-Eibrink. Characteristics and outcome of children with renal tumors in the Netherlands: The first five-year's experience of national centralization.
PloS one.
2022; 17(1):e0261729. doi:
10.1371/journal.pone.0261729. [PMID: 35025887] - Oksana Kachur, Liudmyla Fira, Petro Lykhatskyі, Dmytro Fira, Nataliya Garlitska. Evaluation of membrane-destructive processes in rats with induced carcinogenesis of the colon using the cytostatic vincristine.
Roczniki Panstwowego Zakladu Higieny.
2022; 73(2):215-220. doi:
10.32394/rpzh.2022.0212. [PMID: 35748566] - Will Harris, Edward J Bataillard, Yoonha Choi, Tarec C El-Galaly, Vaikunth Cuchelkar, Carsten Henneges, Antonia Kwan, Daniel J Schneider, Joseph N Paulson, Tina G Nielsen. TRAIL Score: A Simple Model to Predict Immunochemotherapy Tolerability in Patients With Diffuse Large B-Cell Lymphoma.
JCO clinical cancer informatics.
2022 01; 6(?):e2100121. doi:
10.1200/cci.21.00121. [PMID: 35044836] - Mohammad Rasoul Samandari Bahraseman, Babak Khorsand, Keyvan Esmaeilzadeh-Salestani, Solmaz Sarhadi, Nima Hatami, Banafsheh Khaleghdoust, Evelin Loit. The use of integrated text mining and protein-protein interaction approach to evaluate the effects of combined chemotherapeutic and chemopreventive agents in cancer therapy.
PloS one.
2022; 17(11):e0276458. doi:
10.1371/journal.pone.0276458. [PMID: 36367850] - Yohei Funakoshi, Kimikazu Yakushijin, Goh Ohji, Wataru Hojo, Hironori Sakai, Marika Watanabe, Miki Saeki, Yuri Hirakawa, Rina Sakai, Sakuya Matsumoto, Yu Mizutani, Akihito Kitao, Yoshiharu Miyata, Yasuyuki Saito, Shinichiro Kawamoto, Katsuya Yamamoto, Mitsuhiro Ito, Meiko Nishimura, Yoshinori Imamura, Naomi Kiyota, Hiroshi Matsuoka, Yasuko Mori, Hironobu Minami. Limited increase in antibody titers following mRNA SARS-CoV-2 vaccination for more than 3 years after final dose of anti-CD20 antibody.
International journal of hematology.
2022 Jan; 115(1):7-10. doi:
10.1007/s12185-021-03247-y. [PMID: 34981433] - Osama M Alshehri, Saleh Alshamrani, Mater H Mahnashi, Mohammed Merae Alshahrani, Jalwa Ali Khan, Muhammad Shah, Mohammed Ali Alshehri, Rehman Zafar, Muhammad Zahoor, Muhammad Saeed Jan, Syed Shams Ul Hassan, Abdul Sadiq. Phytochemical Analysis, Total Phenolic, Flavonoid Contents, and Anticancer Evaluations of Solvent Extracts and Saponins of H. digitata.
BioMed research international.
2022; 2022(?):9051678. doi:
10.1155/2022/9051678. [PMID: 36246962] - Min Yu, Qian Zhang, Shan Xu, Ting Yin, Fei Li. Successful treatment of refractory retroperitoneal Epstein-Barr virus-positive diffuse large B-cell lymphoma with secondary hemophagocytic syndrome by sequential combination regimen of PD-1 blockade and chimeric antigen receptor T cells: a case report.
Anti-cancer drugs.
2022 01; 33(1):e769-e775. doi:
10.1097/cad.0000000000001187. [PMID: 34387604] - Yun Jung Bae, Hyojin Kim, Wonjae Cha, Byung Se Choi. Primary pharyngeal synovial sarcoma in a pediatric patient: A case report.
Medicine.
2021 Dec; 100(52):e28411. doi:
10.1097/md.0000000000028411. [PMID: 34967377] - Yoshifuru Tamura, Ritsu Sumiyoshi, Tadashi Yamamoto, Yuto Hayama, Yoshihide Fujigaki, Shigeru Shibata, Yuko Sasajima, Haruko Tashiro. Bilateral nephromegaly due to direct leukemic cell invasion in the initial and relapse phases of T-cell acute lymphoblastic leukaemia: A case report.
Medicine.
2021 Dec; 100(51):e28391. doi:
10.1097/md.0000000000028391. [PMID: 34941173] - Chiara Camerini, Emanuela Sant'Antonio, Alessandro Ginori, Marco Pellegri, Cataldo De Gaudio, Elena Banti, Vincenzo Ciliberti, Manuela Parrini, Laura Bozzoli, Federico Simonetti, Enrico Capochiani. Unusual presentation of extranodal diffuse large B-cell lymphoma in a solid-organ recipient during long-term immunosuppressive treatment.
Tumori.
2021 Dec; 107(6):NP127-NP130. doi:
10.1177/03008916211040862. [PMID: 34423702] - Mohammed M Nooh, Sherine M Rizk, Nashwa M Saied, Sally M Abdelazim. Carnosine Remedial Effect on Fertility of Male Rats Receiving Cyclophosphamide, Hydroxydaunomycin, Oncovin and Prednisone (CHOP).
Andrologia.
2021 Dec; 53(11):e14233. doi:
10.1111/and.14233. [PMID: 34535909] - Xue Tang, Ju Gao, Zhi-Gui Ma, Xia Guo, Qiang Li, Zhi Wan, Jing-Jing Sun. Clinical and prognostic characteristics of 95 cases of Langerhans cell histiocytosis in children: a single-institute experience from 2013 to 2020.
Annals of medicine.
2021 12; 53(1):1537-1546. doi:
10.1080/07853890.2021.1966085. [PMID: 34459688] - Sananda Pati, Mrinal Kanti Das, Akshay Rana, Emilee Das, Soumyadeep Sarkar, Norbu Sherpa, Supratim Datta. Kaposiform Hemangioendothelioma with Kasabach-Merritt Phenomenon.
Indian journal of pediatrics.
2021 Nov; 88(11):1142-1144. doi:
10.1007/s12098-021-03817-2. [PMID: 34106442] - Huiqin Ding, Shoujun Yuan, Jiangang Wang, Huan Qin, Yantao Han. IL-12 inhibits postoperative residual tumor growth in murine models of sarcoma and renal carcinoma.
Anti-cancer drugs.
2021 11; 32(10):1003-1010. doi:
10.1097/cad.0000000000001114. [PMID: 34145179] - Federica Rinaldi, Francesco Marchesi, Francesca Palombi, Andrea Pelosi, Anna Laura Di Pace, Andrea Sacconi, Irene Terrenato, Ombretta Annibali, Valeria Tomarchio, Mirella Marino, Maria Cantonetti, Sara Vaccarini, Elena Papa, Lorenzo Moretta, Francesco Bertoni, Andrea Mengarelli, Giulia Regazzo, Maria G Rizzo. MiR-22, a serum predictor of poor outcome and therapy response in diffuse large B-cell lymphoma patients.
British journal of haematology.
2021 11; 195(3):399-404. doi:
10.1111/bjh.17734. [PMID: 34318932] - Yongxiang Zhao, Haiyan Cheng, Hongcheng Song, Ruimin Zhang, Xiangming Wu, Haowei Li, Jun Wang, Huanmin Wang, Chunmei Jia. Duplex kidney complicated with preoperative inferior nephroblastoma rupture in children: a case report and literature review.
BMC pediatrics.
2021 10; 21(1):441. doi:
10.1186/s12887-021-02919-2. [PMID: 34625044] - Kazuyuki Shimada, Hitoshi Kiyoi. Current progress and future perspectives of research on intravascular large B-cell lymphoma.
Cancer science.
2021 Oct; 112(10):3953-3961. doi:
10.1111/cas.15091. [PMID: 34327781] - Hassan Mohammadlou, Maryam Hamzeloo-Moghadam, Mohammad Hossein Mohammadi, Amir Yami, Ahmad Gharehbaghian. Britannin, a sesquiterpene lactone induces ROS-dependent apoptosis in NALM-6, REH, and JURKAT cell lines and produces a synergistic effect with vincristine.
Molecular biology reports.
2021 Sep; 48(9):6249-6258. doi:
10.1007/s11033-021-06572-x. [PMID: 34478011] - Chih-Wei Chien, Cheng-Kai Lee, Po-Nan Wang, Pei-Chun Chien, Yu-Ying Hsu, Ling-Hong Tseng. Urethral large B-cell urethral lymphoma: A case report and literature review.
Taiwanese journal of obstetrics & gynecology.
2021 Sep; 60(5):920-923. doi:
10.1016/j.tjog.2021.07.025. [PMID: 34507675] - Venkatesh Pilla Reddy, Adrian J Fretland, Diansong Zhou, Shringi Sharma, Buyun Chen, Karthick Vishwanathan, Dermot F McGinnity, Yan Xu, Joseph A Ware. Mechanistic physiology-based pharmacokinetic modeling to elucidate vincristine-induced peripheral neuropathy following treatment with novel kinase inhibitors.
Cancer chemotherapy and pharmacology.
2021 09; 88(3):451-464. doi:
10.1007/s00280-021-04302-5. [PMID: 34080039] - Ben Sprangers, Leonardo V Riella, Daan Dierickx. Posttransplant Lymphoproliferative Disorder Following Kidney Transplantation: A Review.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2021 08; 78(2):272-281. doi:
10.1053/j.ajkd.2021.01.015. [PMID: 33774079] - Gaurav Dhingra, Manideepa Maji, Saikat Mandal, Sudeep Vaniyath, Gita Negi, Uttam Kumar Nath. COVID 19 infection associated with thrombotic thrombocytopenic purpura.
Journal of thrombosis and thrombolysis.
2021 Aug; 52(2):504-507. doi:
10.1007/s11239-021-02452-0. [PMID: 33904053] - Feride Yilmaz, Serkan Yasar, Meltem Caglar Tuncali, Serkan Akin. Complete response in a frail patient with high-grade B-cell lymphoma to only one cycle of R-CHOP or to prolonged COVID-19?.
Seminars in oncology.
2021 Aug; 48(4-6):279-282. doi:
10.1053/j.seminoncol.2021.11.001. [PMID: 34895738] - Stephen Kimani, Matthew S Painschab, Bongani Kaimila, Edwards Kasonkanji, Takondwa Zuze, Tamiwe Tomoka, Maurice Mulenga, Richard Nyasosela, Maria Chikasema, Asekanadziwa Mtangwanika, Mena Chawinga, Wilberforce Mhango, Simon Nicholas, Fred Chimzimu, Coxcilly Kampani, Robert Krysiak, Amy Lilly, Cara Randall, Ryan Seguin, Katherine D Westmoreland, Nathan D Montgomery, Yuri Fedoriw, Satish Gopal. Safety and efficacy of rituximab in patients with diffuse large B-cell lymphoma in Malawi: a prospective, single-arm, non-randomised phase 1/2 clinical trial.
The Lancet. Global health.
2021 07; 9(7):e1008-e1016. doi:
10.1016/s2214-109x(21)00181-9. [PMID: 34022150] - Hajime Yasuda, Mutsuko Yasuda, Norio Komatsu. Chemotherapy for non-Hodgkin lymphoma in the hemodialysis patient: A comprehensive review.
Cancer science.
2021 Jul; 112(7):2607-2624. doi:
10.1111/cas.14933. [PMID: 33938097] - Chun-Hoe Tan, Joanne Soon-Yee Yeap, Siew-Huah Lim, Yun-Yee Low, Kae-Shin Sim, Toh-Seok Kam. The Bisindole Alkaloids Angustilongines M and A from Alstonia penangiana Induce Mitochondrial Apoptosis and G0/G1 Cell Cycle Arrest in HT-29 Cells through Promotion of Tubulin Polymerization.
Journal of natural products.
2021 05; 84(5):1524-1533. doi:
10.1021/acs.jnatprod.1c00013. [PMID: 33872002] - Tianjiao Tang, Jing Wang, Lidan Zhang, Ying Cheng, Laura Saleh, Yanni Gu, Hongbin Zhang. IQGAP2 acts as an independent prognostic factor and is related to immunosuppression in DLBCL.
BMC cancer.
2021 May; 21(1):603. doi:
10.1186/s12885-021-08086-y. [PMID: 34034707] - Satya Prakash Yadav, Teena Wadhwa, Dhwanee Thakkar, Rohit Kapoor, Neha Rastogi, Smita Sarma. COVID-19 reinfection in two children with cancer.
Pediatric hematology and oncology.
2021 05; 38(4):403-405. doi:
10.1080/08880018.2020.1855276. [PMID: 33625290] - Nobuhiko Yamauchi, Dai Maruyama, Ilseung Choi, Yoshiko Atsuta, Rika Sakai, Kazuho Miyashita, Yukiyoshi Moriuchi, Hideki Tsujimura, Nobuko Kubota, Go Yamamoto, Tadahiko Igarashi, Koji Izutsu, Shinichiro Yoshida, Kensuke Kojima, Toshiki Uchida, Yoshiko Inoue, Norifumi Tsukamoto, Eiichi Ohtsuka, Sachiko Suzuki, Yoko Inaguma, Satoshi Ichikawa, Hiroshi Gomyo, Yoko Ushijima, Kisato Nosaka, Mio Kurata, Yasuhito Tanaka, Ryuzo Ueda, Masashi Mizokami, Shigeru Kusumoto. Prophylactic antiviral therapy for hepatitis B virus surface antigen-positive patients with diffuse large B-cell lymphoma treated with rituximab-containing chemotherapy.
Cancer science.
2021 May; 112(5):1943-1954. doi:
10.1111/cas.14846. [PMID: 33576088] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Mrinmoy Gautam, Muthiah Ramanathan. Ameliorative potential of flavonoids of Aegle marmelos in vincristine-induced neuropathic pain and associated excitotoxicity.
Nutritional neuroscience.
2021 Apr; 24(4):296-306. doi:
10.1080/1028415x.2019.1627768. [PMID: 31221045] - Pablo Mozas, Andrea Rivero, Alfredo Rivas-Delgado, Aleix Fabregat, Juan A Piñeyroa, Juan G Correa, Ferran Nadeu, Aina Oliver, Alex Bataller, Eva Giné, Julio Delgado, Neus Villamor, Maria T Cibeira, Carlos Fernández de Larrea, Laura Rosiñol, Elías Campo, Juan I Aróstegui, Joan Bladé, Laura Magnano, Armando López-Guillermo. Baseline correlations and prognostic impact of serum monoclonal proteins in follicular lymphoma.
British journal of haematology.
2021 04; 193(2):299-306. doi:
10.1111/bjh.17138. [PMID: 33200406] - Yan Jin, Yang Li, Muhammad Erfan Uddin, Alex Sparreboom, Shuiying Hu. Rapid quantification of vincristine in mouse plasma using ESI-LC-MS/MS: Application to pharmacokinetic studies.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2021 Apr; 1168(?):122591. doi:
10.1016/j.jchromb.2021.122591. [PMID: 33684722] - Toshiaki Igarashi, Shinji Kishi, Naoko Hosono, Takashi Higashi, Takahiro Iwao, Ryoichi Yano, Hitoshi Tsukamoto, Nobuyuki Goto, Takahiro Yamauchi, Takanori Ueda. Population pharmacokinetic model development and exposure-response analysis of vincristine in patients with malignant lymphoma.
Cancer chemotherapy and pharmacology.
2021 04; 87(4):501-511. doi:
10.1007/s00280-020-04220-y. [PMID: 33416909] - S Bernard, L Hachon, J F Diasonama, C Madaoui, L Aguinaga, E Miekoutima, H Moatti, Emeline Perrial, I Madelaine, P Brice, Catherine Thieblemont. Ambulatory high-dose methotrexate administration as central nervous system prophylaxis in patients with aggressive lymphoma.
Annals of hematology.
2021 Apr; 100(4):979-986. doi:
10.1007/s00277-020-04341-7. [PMID: 33608849] - Nan Jiang, Lingzhi Wang, Xiaoqiang Xiang, Zhenhua Li, Edwynn Kean Hui Chiew, Yok Moi Koo, How Sung Lee, Hai Peng Lin, Ah Moy Tan, Thuan Chong Quah, Shirley Kow Yin Kham, Boon Cher Goh, Hany Ariffin, Allen Eng-Juh Yeoh. Intracellular vincristine levels in lymphoblasts affect treatment outcome in childhood B-lymphoblastic leukaemia: Ma-Spore ALL 2010 study.
British journal of clinical pharmacology.
2021 04; 87(4):1990-1999. doi:
10.1111/bcp.14596. [PMID: 33037681] - Shu Liu, He Huang, Rong-Xin Chen, Zhao Wang, Yan-Ping Guan, Chen Peng, Xiao-Jie Fang, Zhuo-Jia Chen, Shao-Xing Guan, Xia Zhu, Quan-Guang Ren, Yu-Yi Yao, Hong-Bing Huang, Min Huang, Xue-Ding Wang, Tong-Yu Lin. Low initial trough concentration of rituximab is associated with unsatisfactory response of first-line R-CHOP treatment in patients with follicular lymphoma with grade 1/2.
Acta pharmacologica Sinica.
2021 Apr; 42(4):641-647. doi:
10.1038/s41401-020-0479-2. [PMID: 32737470] - Arlley Cleverson Belo da Silva, Jurandir Piassi Passos, Roney Cesar Signorini Filho, Antonio Braga, Rosiane Mattar, Sue Yazaki Sun. Uterine Rescue in High-Risk Gestational Trophoblastic Neoplasia Treated with EMA-CO by Uterine Arteries Embolization due to Arteriovenous Malformations.
Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia.
2021 Apr; 43(4):323-328. doi:
10.1055/s-0041-1725054. [PMID: 33979893] - Masaki Mitobe, Keisuke Kawamoto, Takaharu Suzuki, Tatsuya Suwabe, Yasuhiko Shibasaki, Masayoshi Masuko, Kanako Inoue, Hiroaki Miyoshi, Koichi Ohshima, Hirohito Sone, Jun Takizawa. DA-EPOCH-R therapy for high-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements in a patient with renal dysfunction.
Journal of clinical and experimental hematopathology : JCEH.
2021 Mar; 61(1):42-47. doi:
10.3960/jslrt.20043. [PMID: 33551436] - Woo Hyuk Lee, Sun Kyoung You, Yeon-Hee Lee. Bilateral optic neuropathy following vincristine chemotherapy: A case report with description of multimodal imaging findings.
Medicine.
2021 Mar; 100(9):e24706. doi:
10.1097/md.0000000000024706. [PMID: 33655935] - Margaret E Duckett, Kaitlin M Curran, Haley J Leeper, Carl E Ruby, Shay Bracha. Fasting reduces the incidence of vincristine-associated adverse events in dogs.
Veterinary and comparative oncology.
2021 Mar; 19(1):61-68. doi:
10.1111/vco.12638. [PMID: 33448618] - Ali Zahit Bolaman, Cem Selim, Can Karaman, İrfan Yavaşoğlu. Masquerading of COVID-19 Infection as Primary Mediastinal Large B-Cell Lymphoma.
Turkish journal of haematology : official journal of Turkish Society of Haematology.
2021 02; 38(1):77-78. doi:
10.4274/tjh.galenos.2020.2020.0340. [PMID: 33491812] - Hang-Yu Chen, Wei-Long Zhang, Lei Zhang, Ping Yang, Fang Li, Ze-Ruo Yang, Jing Wang, Meng Pang, Yun Hong, Changjian Yan, Wei Li, Jia Liu, Nuo Xu, Long Chen, Xiu-Bing Xiao, Yan Qin, Xiao-Hui He, Hui Liu, Hai-Chuan Zhu, Chuan He, Jian Lin, Hong-Mei Jing. 5-Hydroxymethylcytosine profiles of cfDNA are highly predictive of R-CHOP treatment response in diffuse large B cell lymphoma patients.
Clinical epigenetics.
2021 02; 13(1):33. doi:
10.1186/s13148-020-00973-8. [PMID: 33573703] - Bilel Mhedhbi, Soumaya Chargui, Amel Harzallah, Rim Goucha. Proliferative glomerulonephritis and mantle cell lymphoma: a rare association.
BMJ case reports.
2021 Feb; 14(2):. doi:
10.1136/bcr-2020-238153. [PMID: 33547121] - Ana Tadijan, Ivana Samaržija, Jonathan D Humphries, Martin J Humphries, Andreja Ambriović-Ristov. KANK family proteins in cancer.
The international journal of biochemistry & cell biology.
2021 02; 131(?):105903. doi:
10.1016/j.biocel.2020.105903. [PMID: 33309958] - Ziyuan Wang, Xiaoting Sun, Yuanyuan Feng, Yang Wang, Lu Zhang, Yan Wang, Zhen Fang, Nisma Lena Bahaji Azami, Mingyu Sun, Qi Li. Dihydromyricetin reverses MRP2-induced multidrug resistance by preventing NF-κB-Nrf2 signaling in colorectal cancer cell.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2021 Feb; 82(?):153414. doi:
10.1016/j.phymed.2020.153414. [PMID: 33461143] - Rina Oba, Kentaro Koike, Masahiro Okabe, Kei Matsumoto, Nobuo Tsuboi, Takashi Yokoo. A case of intravascular large B-cell lymphoma with renal involvement presenting with elevated serum ANCA titers.
CEN case reports.
2021 02; 10(1):59-63. doi:
10.1007/s13730-020-00515-4. [PMID: 32776181] - Mahmoud A Senousy, Aya M El-Abd, Raafat R Abdel-Malek, Sherine M Rizk. Circulating long non-coding RNAs HOTAIR, Linc-p21, GAS5 and XIST expression profiles in diffuse large B-cell lymphoma: association with R-CHOP responsiveness.
Scientific reports.
2021 01; 11(1):2095. doi:
10.1038/s41598-021-81715-5. [PMID: 33483590] - Junichi Nakagawa, Takenori Takahata, Rui Hyodo, Yu Chen, Kengo Hasui, Kota Sasaki, Kensuke Saito, Kayo Ueno, Kazuhiro Hosoi, Kazufumi Terui, Atsushi Sato, Takenori Niioka. Evaluation for pharmacokinetic exposure of cytotoxic anticancer drugs in elderly patients receiving (R-)CHOP therapy.
Scientific reports.
2021 01; 11(1):785. doi:
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