3-Hydroxybenzo(a)pyrene (BioDeep_00000003650)
Secondary id: BioDeep_00001875297
human metabolite blood metabolite
代谢物信息卡片
pentacyclo[10.6.2.0²,⁷.0⁹,¹⁹.0¹⁶,²⁰]icosa-1(18),2,4,6,8,10,12,14,16,19-decaen-13-ol
化学式: C20H12O (268.0888)
中文名称: 3-羟基苯并[a]芘
谱图信息:
最多检出来源 Homo sapiens(blood) 9.2%
分子结构信息
SMILES: C1=CC=C2C3=C4C(=CC2=C1)C=CC5=C(C=CC(=C54)C=C3)O
InChI: InChI=1S/C20H12O/c21-18-10-7-12-5-8-16-15-4-2-1-3-13(15)11-14-6-9-17(18)19(12)20(14)16/h1-11,21H
描述信息
CONFIDENCE standard compound; INTERNAL_ID 45
同义名列表
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:34337
- KEGG: C14461
- PubChem: 25890
- HMDB: HMDB0248998
- Metlin: METLIN70079
- ChEMBL: CHEMBL8020
- CAS: 13345-21-6
- MoNA: UA004502
- MoNA: UA004501
- MoNA: UA004504
- MoNA: UA004503
- PMhub: MS000010713
- PubChem: 17395461
- PDB-CCD: 8SK
- NIKKAJI: J2.737E
- KNApSAcK: 34337
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Linjing Deng, Hui Liu, Qihong Deng. Physiologically-based pharmacokinetic modeling of benzo(a)pyrene and the metabolite in humans of different ages.
International journal of environmental health research.
2021 Mar; 31(2):202-214. doi:
10.1080/09603123.2019.1640355. [PMID: 31296039] - Kai Luo, Qun Gao, Jianying Hu. Determination of 3-Hydroxybenzo[a]pyrene Glucuronide/Sulfate Conjugates in Human Urine and Their Association with 8-Hydroxydeoxyguanosine.
Chemical research in toxicology.
2019 07; 32(7):1367-1373. doi:
10.1021/acs.chemrestox.9b00025. [PMID: 31204473] - Ayman Alhamdow, Håkan Tinnerberg, Christian Lindh, Maria Albin, Karin Broberg. Cancer-related proteins in serum are altered in workers occupationally exposed to polycyclic aromatic hydrocarbons: a cross-sectional study.
Carcinogenesis.
2019 07; 40(6):771-781. doi:
10.1093/carcin/bgz022. [PMID: 30753342] - Ayman Alhamdow, Christian Lindh, Maria Albin, Per Gustavsson, Håkan Tinnerberg, Karin Broberg. Cardiovascular disease-related serum proteins in workers occupationally exposed to polycyclic aromatic hydrocarbons.
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2019 Jun; ?(?):. doi:
10.1093/toxsci/kfz142. [PMID: 31228248] - Sigrid Richter-Brockmann, Gerhard Dettbarn, Soenke Jessel, Andrea John, Albrecht Seidel, Christine Achten. Ultra-high sensitive analysis of 3-hydroxybenzo[a]pyrene in human urine using GC-APLI-MS.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2019 Jun; 1118-1119(?):187-193. doi:
10.1016/j.jchromb.2019.04.007. [PMID: 31055084] - Flavio Raponi, Lisa Bauleo, Carla Ancona, Francesco Forastiere, Enrico Paci, Daniela Pigini, Giovanna Tranfo. Quantification of 1-hydroxypyrene, 1- and 2-hydroxynaphthalene, 3-hydroxybenzo[a]pyrene and 6-hydroxynitropyrene by HPLC-MS/MS in human urine as exposure biomarkers for environmental and occupational surveys.
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2016 09; 28(11):520-35. doi:
10.1080/08958378.2016.1214768. [PMID: 27569524] - Huan Hu, Baizhan Liu, Jun Yang, Zuomin Lin, Wuer Gan. Sensitive determination of trace urinary 3-hydroxybenzo[a]pyrene using ionic liquids-based dispersive liquid-liquid microextraction followed by chemical derivatization and high performance liquid chromatography-high resolution tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2016 Aug; 1027(?):200-6. doi:
10.1016/j.jchromb.2016.05.041. [PMID: 27294533] - Simon Lutier, Anne Maître, Vincent Bonneterre, Dominique J Bicout, Marie Marques, Renaud Persoons, Damien Barbeau. Urinary elimination kinetics of 3-hydroxybenzo(a)pyrene and 1-hydroxypyrene of workers in a prebake aluminum electrode production plant: Evaluation of diuresis correction methods for routine biological monitoring.
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