Isoprothiolane (BioDeep_00000003512)
Secondary id: BioDeep_00000398140
human metabolite Endogenous
代谢物信息卡片
化学式: C12H18O4S2 (290.0646)
中文名称: 甲醇中稻瘟灵溶液
谱图信息:
最多检出来源 not specific(not specific) 0%
分子结构信息
SMILES: CC(C)OC(=O)C(=C1SCCS1)C(=O)OC(C)C
InChI: InChI=1S/C12H18O4S2/c1-7(2)15-10(13)9(11(14)16-8(3)4)12-17-5-6-18-12/h7-8H,5-6H2,1-4H3
描述信息
Isoprothiolane is an Agricultural fungicide for rice crop
同义名列表
20 个代谢物同义名
1,3-bis(propan-2-yl) 2-(1,3-dithiolan-2-ylidene)propanedioate; Bis(1-methylethyl) 1,3-dithiolan-2-ylidenepropanedioate, 9ci; Bis(1-methylethyl) 1,3-dithiolan-2-ylidenepropanedioic acid; Bis(1-methylethyl) 1,3-dithiolan-2-ylidenepropanedioate; Diisopropyl 2-(1,3-dithiolan-2-ylidene)malonic acid; Di-isopropyl 1,3-dithiolane-2-ylidenemalonic acid; Di(propan-2-yl) 1,3-dithiolan-2-ylidenemalonate; Diisopropyl 1,3-dithiolan-2-ylidenemalonic acid; Diisopropyl 2-(1,3-dithiolan-2-ylidene)malonate; Di-isopropyl 1,3-dithiolane-2-ylidenemalonate; Diisopropyl 1,3-dithiolan-2-ylidenemalonate; Ipt (pesticide); Isoprothiolane; Fudiolan; Fuji-one; Fudzivan; Fujione; Fuji 1; IPT; Isoprothiolane
数据库引用编号
14 个数据库交叉引用编号
- ChEBI: CHEBI:6047
- KEGG: C11111
- PubChem: 39681
- HMDB: HMDB0031779
- Metlin: METLIN68852
- ChEMBL: CHEMBL35280
- foodb: FDB008452
- chemspider: 36283
- CAS: 50512-35-1
- PMhub: MS000009853
- PubChem: 13293
- NIKKAJI: J3.513K
- RefMet: Isoprothiolane
- KNApSAcK: 6047
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ruiqing Bi, Renjian Li, Zhenyi Xu, Huanyu Cai, Juan Zhao, Yaru Zhou, Bangting Wu, Peng Sun, Wei Yang, Lu Zheng, Xiao-Lin Chen, Chao-Xi Luo, Huailong Teng, Qiang Li, Guotian Li. Melatonin targets MoIcl1 and works synergistically with fungicide isoprothiolane in rice blast control.
Journal of pineal research.
2023 Sep; 75(2):e12896. doi:
10.1111/jpi.12896. [PMID: 37458404] - Fan-Zhu Meng, Zuo-Qian Wang, Mei Luo, Wen-Kai Wei, Liang-Fen Yin, Wei-Xiao Yin, Guido Schnabel, Chao-Xi Luo. The velvet family proteins mediate low resistance to isoprothiolane in Magnaporthe oryzae.
PLoS pathogens.
2023 Jun; 19(6):e1011011. doi:
10.1371/journal.ppat.1011011. [PMID: 37276223] - W H Wu, L Wang, S Zhang, Y Q Liang, X L Zheng, K X Yi, C P He. Assessment of sensitivity and virulence fitness costs of the AvrPik alleles from Magnaporthe oryzae to isoprothiolane.
Genetics and molecular research : GMR.
2014 Nov; 13(4):9701-9. doi:
10.4238/2014.november.24.1. [PMID: 25501181] - Dasharath P Oulkar, Kaushik Banerjee, Manoj S Ghaste, Sahadeo D Ramteke, Dattatraya G Naik, Shubhangi B Patil, Manjusha R Jadhav, Pandurang G Adsule. Multiresidue analysis of multiclass plant growth regulators in grapes by liquid chromatography/tandem mass spectrometry.
Journal of AOAC International.
2011 May; 94(3):968-77. doi:
. [PMID: 21797026] - Hiroyuki Kojima, Fumihiro Sata, Shinji Takeuchi, Tatsuya Sueyoshi, Tadanori Nagai. Comparative study of human and mouse pregnane X receptor agonistic activity in 200 pesticides using in vitro reporter gene assays.
Toxicology.
2011 Feb; 280(3):77-87. doi:
10.1016/j.tox.2010.11.008. [PMID: 21115097] - V Jegathambigai, M D S D Karunaratne, A Svinningen, G Mikunthan. Potential of Trichoderma species on Helminthosporium causing leaf spot on cane palm, Chrysalidocarpus lutescens.
Communications in agricultural and applied biological sciences.
2008; 73(2):207-16. doi:
". [PMID: 19226758] - Tomomi Tanaka, Tomiyuki Hori, Takashi Asada, Kikuo Oikawa, Kuniaki Kawata. Simple one-step extraction and cleanup by pressurized liquid extraction for gas chromatographic-mass spectrometric determination of pesticides in green leafy vegetables.
Journal of chromatography. A.
2007 Dec; 1175(2):181-6. doi:
10.1016/j.chroma.2007.10.060. [PMID: 17996881] - Soon-Kil Cho, A M Abd El-Aty, Young-Seok Park, Jeong-Heui Choi, Sathya Khay, Cheol-Ah Kang, Byung-Jun Park, Sun-Ju Kim, Jae-Han Shim. A multiresidue method for the analysis of pesticide residues in polished rice (Oryza sativa L.) using accelerated solvent extraction and gas chromatography and confirmation by mass spectrometry.
Biomedical chromatography : BMC.
2007 Jun; 21(6):602-9. doi:
10.1002/bmc.792. [PMID: 17385804] - Fayez A Bakry, Adel A Sakrane, Nahed M M Ismail. Molluscicidal effect of fungicide, herbicide and plant extract on some biological and physiological parameters of Biomphalaria alexandrina.
Journal of the Egyptian Society of Parasitology.
2002 Dec; 32(3):821-35. doi:
. [PMID: 12512815] - Z H Zidan, F M A Ragab, K H A Mohamed. Molluscicidal activities of certain pesticide and their mixtures against Biomphalaria alexandrina.
Journal of the Egyptian Society of Parasitology.
2002 Apr; 32(1):285-96. doi:
. [PMID: 12049263] - H Okada, Y Miyake, H Ohtsuka, Y Kiku, S Fukuda, A Watanabe, Y Yokomizo, T J Rosol, T Yoshino. Effects of isoprothiolane on cell growth of cultured bovine mammary epithelial cells.
The Journal of veterinary medical science.
1999 May; 61(5):553-6. doi:
10.1292/jvms.61.553. [PMID: 10379950] - H Jinno, N Hanioka, S Nishikawa, R Yoda, T Toyo'oka, T Nishimura, M Ando. Hepatotoxicity of diisopropyl ester of malonic acid and chloromalonic acids, disinfection by-products of the fungicide isoprothiolane.
Archives of toxicology.
1997; 71(9):550-5. doi:
10.1007/s002040050426. [PMID: 9285037] - H Katamoto, N Yoneda, Y Shimada. Effects of isoprothiolane and phytosterol on adipocyte metabolism and fatty acid composition of serum and tissue lipids in rats.
The Journal of veterinary medical science.
1991 Oct; 53(5):905-10. doi:
10.1292/jvms.53.905. [PMID: 1836380] - H Katamoto, S Kurihara, Y Shimada. Effects of isoprothiolane and phytosterol on lipogenesis and lipolysis in adipocytes from rats of dietary fat necrosis.
Nihon juigaku zasshi. The Japanese journal of veterinary science.
1990 Dec; 52(6):1189-97. doi:
10.1292/jvms1939.52.1189. [PMID: 2287126] - S Nagasawa, H Yamanaka, Y Motoi, T Ishikawa, T Takizawa. Effect of isoprothiolane on hepatic lesions of heifer caused by carbon tetrachloride.
Nihon juigaku zasshi. The Japanese journal of veterinary science.
1989 Apr; 51(2):284-93. doi:
10.1292/jvms1939.51.284. [PMID: 2739204] - A Oka, T Yamasaki, M Shibatani, T Suzuki, T Saito. Efficacy of isoprothiolane for the treatment of fat necrosis in cattle.
The British veterinary journal.
1988 Sep; 144(5):507-14. doi:
10.1016/0007-1935(88)90091-7. [PMID: 3056570] - Y Akiba, K Takahashi, T Matsumoto. Effect of diisopropyl 1,3-dithiolan-2-ylidenemalonate on experimental fatty livers in chicks.
Poultry science.
1984 Jan; 63(1):117-22. doi:
10.3382/ps.0630117. [PMID: 6701137] - S S Chou, M Eto. Effects of paddy water and some photosensitizers on the photolysis of the fungicide isoprothiolane.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes.
1980; 15(2):135-46. doi:
10.1080/03601238009372170. [PMID: 7365205]
