Palmitoylcarnitine (BioDeep_00000003254)

Main id: BioDeep_00000641215

Secondary id: BioDeep_00000405221, BioDeep_00001891269

human metabolite blood metabolite LipidSearch natural product


代谢物信息卡片


O-hexadecanoyl-R-carnitine

化学式: C23H45NO4 (399.3348)
中文名称: 棕榈酰左旋肉碱, 棕榈酰-L-肉碱
谱图信息: 最多检出来源 Homo sapiens(lipidomics) 18.94%

分子结构信息

SMILES: CCCCCCCCCCCCCCCC(=O)OC(CC(=O)[O-])C[N+](C)(C)C
InChI: InChI=1S/C23H45NO4/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(27)28-21(19-22(25)26)20-24(2,3)4/h21H,5-20H2,1-4H3

描述信息

D018977 - Micronutrients > D014815 - Vitamins
CONFIDENCE standard compound; INTERNAL_ID 250

同义名列表

8 个代谢物同义名

O-hexadecanoyl-R-carnitine; Palmitoyl-L-carnitine; L-Palmitoylcarnitine; PALMITOYLCARNITINE; CAR 16:0; Palmitoylcarnitine; L-Palmitoylcarnitine; Palmitoyl-L-carnitine



数据库引用编号

22 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(7)

BioCyc(0)

PlantCyc(0)

代谢反应

120 个相关的代谢反应过程信息。

Reactome(84)

BioCyc(2)

WikiPathways(1)

Plant Reactome(0)

INOH(0)

PlantCyc(1)

COVID-19 Disease Map(0)

PathBank(32)

PharmGKB(0)

21 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 ACADL, ALB, GAP43, HADH, ODC1, PLA2G12A, PRKX
Peripheral membrane protein 3 CPT2, CRAT, GAP43
Mitochondrion membrane 1 SLC25A20
Nucleus 3 ALB, CS, PRKX
cytosol 6 ALB, CRAT, MB, ODC1, PRKCQ, SLC25A20
dendrite 1 GAP43
mitochondrial membrane 1 ACADL
centrosome 1 ALB
nucleoplasm 4 ATP2B1, CPT2, HADH, PRKX
Cell membrane 2 ATP2B1, GAP43
Cytoplasmic side 1 GAP43
Cell projection, axon 1 GAP43
Multi-pass membrane protein 5 ATP2B1, CACNA1I, SLC25A20, UCP2, UCP3
Synapse 2 ATP2B1, GAP43
glutamatergic synapse 1 ATP2B1
Golgi apparatus 1 ALB
Golgi membrane 1 INS
mitochondrial inner membrane 6 CPT2, CRAT, HADH, SLC25A20, UCP2, UCP3
presynaptic membrane 1 ATP2B1
Presynapse 1 GAP43
plasma membrane 5 ATP2B1, CACNA1I, GAP43, KNG1, PRKCQ
synaptic vesicle membrane 1 ATP2B1
Membrane 4 ATP2B1, CACNA1I, CS, SLC25A20
basolateral plasma membrane 1 ATP2B1
extracellular exosome 5 ALB, ATP2B1, CS, KNG1, MB
endoplasmic reticulum 2 ALB, CRAT
extracellular space 4 ALB, IL6, INS, KNG1
mitochondrion 8 ACADL, CPT2, CRAT, CS, HADH, SLC25A20, UCP2, UCP3
protein-containing complex 1 ALB
intracellular membrane-bounded organelle 1 ATP2B1
postsynaptic density 1 GAP43
Secreted 4 ALB, IL6, INS, PLA2G12A
extracellular region 5 ALB, IL6, INS, KNG1, PLA2G12A
Mitochondrion matrix 3 ACADL, CS, HADH
mitochondrial matrix 3 ACADL, CS, HADH
anchoring junction 1 ALB
centriolar satellite 1 PRKCQ
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
perikaryon 1 GAP43
nucleolus 1 CPT2
sarcoplasm 1 MB
Mitochondrion inner membrane 5 CPT2, CRAT, HADH, UCP2, UCP3
Matrix side 2 CPT2, CRAT
GABA-ergic synapse 1 GAP43
mitochondrial nucleoid 1 HADH
Peroxisome 1 CRAT
peroxisomal matrix 1 CRAT
collagen-containing extracellular matrix 1 KNG1
lateral plasma membrane 1 ATP2B1
ciliary basal body 1 ALB
cell projection 1 ATP2B1
centriole 1 ALB
Secreted, extracellular space 1 KNG1
[Isoform 1]: Mitochondrion 1 CRAT
spindle pole 1 ALB
blood microparticle 2 ALB, KNG1
Basolateral cell membrane 1 ATP2B1
endosome lumen 1 INS
Cell projection, dendrite 1 GAP43
Presynaptic cell membrane 1 ATP2B1
filopodium membrane 1 GAP43
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 4 ALB, IL6, INS, KNG1
platelet alpha granule lumen 2 ALB, KNG1
voltage-gated calcium channel complex 1 CACNA1I
transport vesicle 1 INS
mitochondrial fatty acid beta-oxidation multienzyme complex 1 HADH
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
mitochondrial envelope 1 SLC25A20
immunological synapse 2 ATP2B1, PRKCQ
aggresome 1 PRKCQ
Cell projection, filopodium membrane 1 GAP43
Cytoplasm, sarcoplasm 1 MB
interleukin-6 receptor complex 1 IL6
photoreceptor ribbon synapse 1 ATP2B1
Cell projection, growth cone membrane 1 GAP43
growth cone membrane 1 GAP43
[Isoform 2]: Peroxisome 1 CRAT
ciliary transition fiber 1 ALB


文献列表

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  • YueTao Liu, XinQi Li, AiPing Li, Ke Li, XueMei Qin. UHPLC Q-Exactive MS-based spleen metabolomics and lipidomics to explore the effect mechanisms of Danggui Buxue Decoction in anemia mice. Journal of pharmaceutical and biomedical analysis. 2020 Jun; 185(?):113234. doi: 10.1016/j.jpba.2020.113234. [PMID: 32171146]
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  • Larissa Menezes Dos Reis, Douglas Adamoski, Rodolpho Ornitz Oliveira Souza, Carolline Fernanda Rodrigues Ascenção, Krishina Ratna Sousa de Oliveira, Felipe Corrêa-da-Silva, Fábio Malta de Sá Patroni, Marília Meira Dias, Sílvio Roberto Consonni, Pedro Manoel Mendes de Moraes-Vieira, Ariel Mariano Silber, Sandra Martha Gomes Dias. Dual inhibition of glutaminase and carnitine palmitoyltransferase decreases growth and migration of glutaminase inhibition-resistant triple-negative breast cancer cells. The Journal of biological chemistry. 2019 06; 294(24):9342-9357. doi: 10.1074/jbc.ra119.008180. [PMID: 31040181]
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  • Sree V Chintapalli, Andriy Anishkin, Sean H Adams. Exploring the entry route of palmitic acid and palmitoylcarnitine into myoglobin. Archives of biochemistry and biophysics. 2018 10; 655(?):56-66. doi: 10.1016/j.abb.2018.07.024. [PMID: 30092229]
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