6beta-Hydroxytestosterone (BioDeep_00000002966)

Main id: BioDeep_00000016688

 

human metabolite Endogenous blood metabolite


代谢物信息卡片


(1S,2R,8R,10R,11S,14S,15S)-8,14-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-6-en-5-one

化学式: C19H28O3 (304.2038)
中文名称: 6,17-二羟基-6b,17b-雄甾-4-烯-3-酮
谱图信息: 最多检出来源 Homo sapiens(blood) 49.67%

分子结构信息

SMILES: C1[C@]2(C)[C@@]3([H])CC[C@]4(C)[C@@H](O)CC[C@@]4([H])[C@]3([H])C[C@@H](O)C2=CC(=O)C1
InChI: InChI=1S/C19H28O3/c1-18-7-5-11(20)9-15(18)16(21)10-12-13-3-4-17(22)19(13,2)8-6-14(12)18/h9,12-14,16-17,21-22H,3-8,10H2,1-2H3/t12-,13-,14-,16+,17-,18+,19-/m0/s1

描述信息

Testosterone is reported to have an acute vasodilating action in vitro, an effect that may impart a favourable haemodynamic response in patients with chronic heart failure.

同义名列表

30 个代谢物同义名

(1S,2R,8R,10R,11S,14S,15S)-8,14-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-6-en-5-one; 6 beta-Hydroxytestosterone, (6alpha,17beta)-isomer; 6,17-Dihydroxy-(6beta,17beta)-androst-4-en-3-one; (6beta,17beta)-6,17-Dihydroxyandrost-4-en-3-one; 6,17-Dihydroxyandrost-4-en-3-one (acd/name 4.0); 6 beta-Hydroxytestosterone, (17beta)-isomer; 6,17-Dihydroxy-(6b,17b)-androst-4-en-3-one; (6b,17b)-6,17-Dihydroxyandrost-4-en-3-one; (6β,17β)-6,17-dihydroxyandrost-4-en-3-one; 6beta,17beta-Dihydroxy-4-androsten-3-one; 6beta,17beta-dihydroxyandrost-4-en-3-one; 2-Octadecanoyl-1-hexadecyl-sn-glycerol; 4-Androsten-6beta,17beta-diol-3-one; 6b,17b-Dihydroxyandrost-4-en-3-one; 6b,17b-Dihydroxy-4-androsten-3-one; 6β,17β-dihydroxy-4-androsten-3-one; 6β,17β-dihydroxyandrost-4-en-3-one; 4-Androsten-6b,17b-diol-3-one; 4-Androsten-6β,17β-diol-3-one; 6 beta Hydroxy testosterone; 6β-hydroxytestosterone; 4-Androsten-6,17-diol-3-one; 6-B-HYDROXY TESTOSTERONE-D3; 6 beta-Hydroxytestosterone; 6beta-hydroxytestosterone; 6 β hydroxy testosterone; 6b-Hydroxytestosterone; 6β-hydroxytestosterone; ST 19:2;O3; 6beta-Hydroxytestosterone



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(6)

BioCyc(0)

PlantCyc(0)

代谢反应

72 个相关的代谢反应过程信息。

Reactome(72)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 11 ABCB1, ACE, APOE, CYP2A6, CYP2C19, CYP2C9, CYP2D6, CYP2E1, CYP3A4, EDN1, FAS
Peripheral membrane protein 1 CYP2E1
Endoplasmic reticulum membrane 8 CYP1A2, CYP2A6, CYP2C19, CYP2C9, CYP2D6, CYP2E1, CYP3A4, CYP3A7
Nucleus 2 APOE, NR1I2
cytosol 1 FAS
dendrite 1 APOE
nuclear body 2 FAS, NR1I2
nucleoplasm 1 NR1I2
Cell membrane 6 ABCB1, ACE, AGTR1, FAS, GPRC5A, GPRC6A
Multi-pass membrane protein 5 ABCB1, AGTR1, DUOX1, GPRC5A, GPRC6A
cell surface 4 ABCB1, DUOX1, FAS, GPRC6A
glutamatergic synapse 1 APOE
Golgi apparatus 2 APOE, FAS
mitochondrial inner membrane 1 CYP2E1
neuronal cell body 1 APOE
Lysosome 1 ACE
endosome 1 ACE
plasma membrane 11 ABCB1, ACE, AGTR1, APOE, CYP2C19, CYP2C9, DUOX1, FAS, GPRC5A, GPRC6A, REN
Membrane 10 ABCB1, ACE, AGTR1, APOE, CYP2A6, CYP2D6, CYP3A4, DUOX1, FAS, REN
apical plasma membrane 2 ABCB1, DUOX1
extracellular exosome 6 ABCB1, ACE, AGT, APOE, FAS, GPRC5A
endoplasmic reticulum 3 APOE, CYP2D6, DUOX1
extracellular space 5 ACE, AGT, APOE, EDN1, REN
mitochondrion 1 CYP2D6
intracellular membrane-bounded organelle 8 CYP1A2, CYP2A6, CYP2C19, CYP2C9, CYP2D6, CYP2E1, CYP3A4, GPRC5A
Microsome membrane 6 CYP1A2, CYP2C9, CYP2D6, CYP2E1, CYP3A4, CYP3A7
Single-pass type I membrane protein 2 ACE, FAS
Secreted 5 ACE, AGT, APOE, EDN1, REN
extracellular region 5 ACE, AGT, APOE, EDN1, REN
Single-pass membrane protein 1 CYP2D6
basal part of cell 1 EDN1
transcription regulator complex 1 NR1I2
external side of plasma membrane 2 ACE, FAS
Endosome, multivesicular body 1 APOE
Extracellular vesicle 1 APOE
Secreted, extracellular space, extracellular matrix 1 APOE
chylomicron 1 APOE
high-density lipoprotein particle 1 APOE
low-density lipoprotein particle 1 APOE
multivesicular body 1 APOE
very-low-density lipoprotein particle 1 APOE
nucleolus 1 GPRC5A
Early endosome 1 APOE
apical part of cell 1 REN
vesicle 1 GPRC5A
Apical cell membrane 2 ABCB1, DUOX1
Mitochondrion inner membrane 1 CYP2E1
Membrane raft 1 FAS
extracellular matrix 1 APOE
collagen-containing extracellular matrix 2 AGT, APOE
receptor complex 1 GPRC5A
chromatin 1 NR1I2
cell leading edge 1 DUOX1
Secreted, extracellular space 1 APOE
brush border membrane 1 ACE
blood microparticle 2 AGT, APOE
sperm midpiece 1 ACE
Cytoplasmic vesicle membrane 1 GPRC5A
Melanosome 2 APOE, FAS
intermediate filament cytoskeleton 1 NR1I2
basal plasma membrane 1 ACE
endoplasmic reticulum lumen 1 APOE
transport vesicle 1 EDN1
clathrin-coated endocytic vesicle membrane 1 APOE
cytoplasmic microtubule 1 CYP2A6
synaptic cleft 1 APOE
external side of apical plasma membrane 1 ABCB1
CD95 death-inducing signaling complex 1 FAS
death-inducing signaling complex 1 FAS
[Isoform 1]: Cell membrane 1 FAS
discoidal high-density lipoprotein particle 1 APOE
endocytic vesicle lumen 1 APOE
chylomicron remnant 1 APOE
intermediate-density lipoprotein particle 1 APOE
lipoprotein particle 1 APOE
multivesicular body, internal vesicle 1 APOE
rough endoplasmic reticulum lumen 1 EDN1
Weibel-Palade body 1 EDN1
NADPH oxidase complex 1 DUOX1
[Angiotensin-converting enzyme, soluble form]: Secreted 1 ACE
[Isoform Testis-specific]: Cell membrane 1 ACE
glycogen granule 1 FAS


文献列表

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