sulfasalazine (BioDeep_00000275651)

Main id: BioDeep_00000002818

 

natural product


代谢物信息卡片


Sulfasalazine (Azulfidine)

化学式: C18H14N4O5S (398.06848740000004)
中文名称: 柳氮磺胺吡啶
谱图信息: 最多检出来源 Viridiplantae(plant) 33.33%

分子结构信息

SMILES: C1(NS(C2=CC=C(C=C2)/N=N/C3=CC(=C(C=C3)O)C(=O)O)(=O)=O)=CC=CC=N1
InChI: InChI=1S/C18H14N4O5S/c23-16-9-6-13(11-15(16)18(24)25)21-20-12-4-7-14(8-5-12)28(26,27)22-17-3-1-2-10-19-17/h1-11,23H,(H,19,22)(H,24,25)

描述信息

A - Alimentary tract and metabolism > A07 - Antidiarrheals, intestinal antiinflammatory/antiinfective agents > A07E - Intestinal antiinflammatory agents > A07EC - Aminosalicylic acid and similar agents
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
D000893 - Anti-Inflammatory Agents
D005765 - Gastrointestinal Agents
D000890 - Anti-Infective Agents
D018501 - Antirheumatic Agents
CONFIDENCE standard compound; INTERNAL_ID 1047; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4230; ORIGINAL_PRECURSOR_SCAN_NO 4229
CONFIDENCE standard compound; INTERNAL_ID 1047; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4221; ORIGINAL_PRECURSOR_SCAN_NO 4220
CONFIDENCE standard compound; INTERNAL_ID 1047; DATASET 20200303_ENTACT_RP_MIX499; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4107; ORIGINAL_PRECURSOR_SCAN_NO 4106
CONFIDENCE standard compound; INTERNAL_ID 1047; DATASET 20200303_ENTACT_RP_MIX499; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4144; ORIGINAL_PRECURSOR_SCAN_NO 4143
CONFIDENCE standard compound; INTERNAL_ID 1047; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4237; ORIGINAL_PRECURSOR_SCAN_NO 4236
CONFIDENCE standard compound; INTERNAL_ID 1047; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4245; ORIGINAL_PRECURSOR_SCAN_NO 4244
CONFIDENCE standard compound; INTERNAL_ID 1047; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8819; ORIGINAL_PRECURSOR_SCAN_NO 8816
CONFIDENCE standard compound; INTERNAL_ID 1047; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8829; ORIGINAL_PRECURSOR_SCAN_NO 8824
CONFIDENCE standard compound; INTERNAL_ID 1047; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8833; ORIGINAL_PRECURSOR_SCAN_NO 8830
CONFIDENCE standard compound; INTERNAL_ID 1047; DATASET 20200303_ENTACT_RP_MIX499; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8842; ORIGINAL_PRECURSOR_SCAN_NO 8838
CONFIDENCE standard compound; INTERNAL_ID 1047; DATASET 20200303_ENTACT_RP_MIX499; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8867; ORIGINAL_PRECURSOR_SCAN_NO 8863
CONFIDENCE standard compound; INTERNAL_ID 1047; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8846; ORIGINAL_PRECURSOR_SCAN_NO 8844

同义名列表

2 个代谢物同义名

sulfasalazine; Sulfasalazine (Azulfidine)



数据库引用编号

41 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yuwen Tian, Tunyu Jian, Jin Li, Lushi Huang, Shen Li, Hao Lu, Guanting Niu, Xiuhua Meng, Bingru Ren, Huarong Liao, Xiaoqin Ding, Jian Chen. Phenolic acids from Chicory roots ameliorate dextran sulfate sodium-induced colitis in mice by targeting TRP signaling pathways and the gut microbiota. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jun; 128(?):155378. doi: 10.1016/j.phymed.2024.155378. [PMID: 38507851]
  • Wei Wu, Wenhao Bu, Yongxing Tan, Yongwang Wang. Effect of sulfasalazine on ferroptosis during intestinal injury in rats after liver transplantation. Scientific reports. 2024 03; 14(1):7349. doi: 10.1038/s41598-024-58057-z. [PMID: 38538748]
  • Begümhan Ömeroğlu Gülada, Muhammet Emin Cam, Meral Yüksel, Dilek Akakın, Turgut Taşkın, Gizem Emre, Göksel Şener, Berna Karakoyun. Gilaburu (Viburnum opulus L.) fruit extract has potential therapeutic and prophylactic role in a rat model of acetic acid-induced oxidant colonic damage. Journal of ethnopharmacology. 2024 Mar; 322(?):117624. doi: 10.1016/j.jep.2023.117624. [PMID: 38128893]
  • Dai Xiaoling, Zhang Anming, Lin Hui, Shi Bei, Ren Yi, Wen Hongzhu, Fei Xiaoyan, Lin Jiang. Qingchang suppositry induced remission in patients with mild-to-moderate ulcerative proctitis: a multicenter, prospective, randomized, parallel-controlled clinical trial. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. 2024 Feb; 44(1):156-162. doi: 10.19852/j.cnki.jtcm.20231121.004. [PMID: 38213250]
  • Alan Cunningham, Lieve Oudejans, Marjan Geugien, Diego A Pereira-Martins, Albertus Tj Wierenga, Ayşegül Erdem, Dominique Sternadt, Gerwin A Huls, Jan Jacob Schuringa. The 'non-essential' amino acid cysteine is required to prevent ferroptosis in acute myeloid leukemia. Blood advances. 2023 Oct; ?(?):. doi: 10.1182/bloodadvances.2023010786. [PMID: 37906522]
  • Narandulam Usukhbayar, Shota Uesugi, Ken-Ichi Kimura. 3,6-Epidioxy-1,10-bisaboladiene and sulfasalazine synergistically induce ferroptosis-like cell death in human breast cancer cell lines. Bioscience, biotechnology, and biochemistry. 2023 Aug; ?(?):. doi: 10.1093/bbb/zbad117. [PMID: 37604790]
  • Urara Idei, Tsuyoshi Ohta, Hizuru Yamatani, Manabu Seino, Satoru Nagase. Mechanism of Cell Death by Combined Treatment with an xCT Inhibitor and Paclitaxel: An Alternative Therapeutic Strategy for Patients with Ovarian Clear Cell Carcinoma. International journal of molecular sciences. 2023 Jul; 24(14):. doi: 10.3390/ijms241411781. [PMID: 37511540]
  • Hikaru Murakami, Masami Hayashi, Shinichi Terada, Masahide Ohmichi. Medroxyprogesterone acetate-resistant endometrial cancer cells are susceptible to ferroptosis inducers. Life sciences. 2023 Jul; 325(?):121753. doi: 10.1016/j.lfs.2023.121753. [PMID: 37160245]
  • Medhat Taha, Sara T Elazab, Omer Abdelbagi, Abdullah A Saati, Omar Babateen, Tourki A S Baokbah, Naeem F Qusty, Mohamed Ezzat Mahmoud, Mohie Mahmoud Ibrahim, Alaa M Badawy. Phytochemical analysis of Origanum majorana L. extract and investigation of its antioxidant, anti-inflammatory and immunomodulatory effects against experimentally induced colitis downregulating Th17 cells. Journal of ethnopharmacology. 2023 Jun; 317(?):116826. doi: 10.1016/j.jep.2023.116826. [PMID: 37348796]
  • Lai-Bo Yin, Zhi-Wei Li, Jing-Ling Wang, Lei Wang, Liang Hou, Si-Yuan Hu, Huan Chen, Pan Luo, Xiao-Bin Cui, Jia-Long Zhu. Sulfasalazine inhibits esophageal cancer cell proliferation by mediating ferroptosis. Chemical biology & drug design. 2023 Jun; ?(?):. doi: 10.1111/cbdd.14281. [PMID: 37291716]
  • Mustafa Cellat, İbrahim Ozan Tekeli, Erdinç Türk, Tuba Aydin, Ahmet Uyar, Cafer Tayer İşler, İshak Gökçek, Muhammed Etyemez, Mehmet Güvenç. Inula viscosa ameliorates acetic acid induced ulcerative colitis in rats. Biotechnic & histochemistry : official publication of the Biological Stain Commission. 2023 May; 98(4):255-266. doi: 10.1080/10520295.2023.2176923. [PMID: 37165766]
  • Abozar Nasiri-Jahrodi, Fatemeh-Maryam Sheikholeslami, Mehdi Barati. Cladosporium tenuissimum-induced sinusitis in a woman with immune-deficiency disorder. Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]. 2023 Apr; ?(?):. doi: 10.1007/s42770-023-00978-4. [PMID: 37101101]
  • Marta Szandruk-Bender, Beata Nowak, Anna Merwid-Ląd, Alicja Z Kucharska, Małgorzata Krzystek-Korpacka, Iwona Bednarz-Misa, Benita Wiatrak, Adam Szeląg, Narcyz Piórecki, Tomasz Sozański. Cornus mas L. Extract Targets the Specific Molecules of the Th17/Treg Developmental Pathway in TNBS-Induced Experimental Colitis in Rats. Molecules (Basel, Switzerland). 2023 Mar; 28(7):. doi: 10.3390/molecules28073034. [PMID: 37049797]
  • Linzhou Yin, Pengyu Liu, Yue Jin, Zunxi Ning, Yiren Yang, Huiyuan Gao. Ferroptosis-related small-molecule compounds in cancer therapy: Strategies and applications. European journal of medicinal chemistry. 2022 Dec; 244(?):114861. doi: 10.1016/j.ejmech.2022.114861. [PMID: 36332549]
  • Ritu Mishra, Neha Jain, Shreya Kaul, Upendra Nagaich. Central composite design-based optimization, fabrication, and pharmacodynamic assessment of sulfasalazine-loaded lipoidal nanoparticle-based hydrogel for the management of rheumatoid arthritis. Drug delivery and translational research. 2022 Dec; ?(?):. doi: 10.1007/s13346-022-01260-0. [PMID: 36515863]
  • Lixia Li, Yingjie Wang, Ling Zhao, Gang Ye, Fei Shi, Yinglun Li, Yuanfeng Zou, Xu Song, Xinghong Zhao, Zhongqiong Yin, Xueyuan Wu, Wen Li, Huaqiao Tang. Sanhuang xiexin decoction ameliorates secondary liver injury in DSS-induced colitis involve regulating inflammation and bile acid metabolism. Journal of ethnopharmacology. 2022 Dec; 299(?):115682. doi: 10.1016/j.jep.2022.115682. [PMID: 36058478]
  • Hussam Murad, Osama Ahmed, Thamer Alqurashi, Mostafa Hussien. Olmesartan medoxomil self-microemulsifying drug delivery system reverses apoptosis and improves cell adhesion in trinitrobenzene sulfonic acid-induced colitis in rats. Drug delivery. 2022 Dec; 29(1):2017-2028. doi: 10.1080/10717544.2022.2086939. [PMID: 35766160]
  • Shaowei Huang, Jinrong He, Yanping Chen, Xiaojing Wang, Yanyang Li, Yulin Su, Ruyan Wen, Xiuling Li, Guanghua Yang, Shuang Luo, Lian Zhou, Xia Luo. Effect of Huangqin decoction on regulating intestinal flora in colitis mice characterized as inhibition of the NOD2-dependent pathway. Pharmaceutical biology. 2022 Dec; 60(1):108-118. doi: 10.1080/13880209.2021.2017981. [PMID: 34967696]
  • Qianwen Zhou, Xiaoqi Wang, Yingxue Zhang, Lie Wang, Zhijun Chen. Inhibition of AEBP1 predisposes cisplatin-resistant oral cancer cells to ferroptosis. BMC oral health. 2022 Nov; 22(1):478. doi: 10.1186/s12903-022-02503-9. [PMID: 36352396]
  • Anil Yilmaz, Fatih Uckaya, Nihan Bayindir, Eray Metin Guler, Ali Toprak, Abdurrahim Kocyigit, Mukaddes Esrefoglu, Gulacti Topcu. Comparing healing effect against ulcerative colitis and toxicological effects of Rosmarinus officinalis: A comprehensive in vivo study of an edible plant in rats. Journal of food biochemistry. 2022 11; 46(11):e14299. doi: 10.1111/jfbc.14299. [PMID: 35778816]
  • Saba Ahmed, Justin Konig, Lora J Kasselman, Heather A Renna, Joshua De Leon, Steven E Carsons, Allison B Reiss. Hydroxychloroquine Effects on THP-1 Macrophage Cholesterol Handling: Cell Culture Studies Corresponding to the TARGET Cardiovascular Trial. Medicina (Kaunas, Lithuania). 2022 Sep; 58(9):. doi: 10.3390/medicina58091287. [PMID: 36143964]
  • Rania M Salama, Samar F Darwish, Ismail El Shaffei, Noura F Elmongy, Nouran M Fahmy, Manal S Afifi, Ghada A Abdel-Latif. Morus macroura Miq. Fruit extract protects against acetic acid-induced ulcerative colitis in rats: Novel mechanistic insights on its impact on miRNA-223 and on the TNFα/NFκB/NLRP3 inflammatory axis. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2022 Jul; 165(?):113146. doi: 10.1016/j.fct.2022.113146. [PMID: 35595039]
  • Junyu Liu, Chenge Lou, Chenxiao Zhen, Yijia Wang, Peng Shang, Huanhuan Lv. Iron plays a role in sulfasalazine-induced ferroptosis with autophagic flux blockage in K7M2 osteosarcoma cells. Metallomics : integrated biometal science. 2022 05; 14(5):. doi: 10.1093/mtomcs/mfac027. [PMID: 35441682]
  • Vasileios Tsamis, Eleni Tsanaktsidou, Christina Karavasili, Constantinos K Zacharis, Nikolaos Bouropoulos, Dimitrios G Fatouros, Catherine K Markopoulou. Development and validation of HPLC-DAD and LC-(ESI)/MS methods for the determination of sulfasalazine, mesalazine and hydrocortisone 21-acetate in tablets and rectal suppositories: In vitro and ex vivo permeability studies. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2022 May; 1198(?):123246. doi: 10.1016/j.jchromb.2022.123246. [PMID: 35405570]
  • Bassem Refaat, Mohamed El-Boshy. Protective antioxidative and anti-inflammatory actions of β-caryophyllene against sulfasalazine-induced nephrotoxicity in rat. Experimental biology and medicine (Maywood, N.J.). 2022 04; 247(8):691-699. doi: 10.1177/15353702211073804. [PMID: 35068213]
  • Simone Forcato, Ana Beatriz de Oliveira Aquino, Nathaly de Moura Camparoto, Hannah Hamada Mendonça Lens, Flávia Alessandra Guarnier, Ana Carolina Inhasz Kiss, Daniela Cristina Ceccatto Gerardin. Sulfasalazine exposure during pregnancy and lactation induces alterations in reproductive behavior in adult female rat offspring. Life sciences. 2022 Mar; 293(?):120303. doi: 10.1016/j.lfs.2022.120303. [PMID: 35051419]
  • Stephen Tong, Tu'uhevaha J Kaitu'u-Lino, Roxanne Hastie, Fiona Brownfoot, Catherine Cluver, Natalie Hannan. Pravastatin, proton-pump inhibitors, metformin, micronutrients, and biologics: new horizons for the prevention or treatment of preeclampsia. American journal of obstetrics and gynecology. 2022 02; 226(2S):S1157-S1170. doi: 10.1016/j.ajog.2020.09.014. [PMID: 32946849]
  • Napapan Kangwan, Sarawut Kongkarnka, Nitsara Boonkerd, Kridsada Unban, Kalidas Shetty, Chartchai Khanongnuch. Protective Effect of Probiotics Isolated from Traditional Fermented Tea Leaves (Miang) from Northern Thailand and Role of Synbiotics in Ameliorating Experimental Ulcerative Colitis in Mice. Nutrients. 2022 Jan; 14(1):. doi: 10.3390/nu14010227. [PMID: 35011101]
  • You Kyoung Shin, Soonho Kwon, Yu Shan Hsieh, A Young Han, Geun Hee Seol. Linalyl acetate restores colon contractility and blood pressure in repeatedly stressed-ulcerative colitis rats. Environmental health and preventive medicine. 2022; 27(0):27. doi: 10.1265/ehpm.22-00041. [PMID: 35753805]
  • Shengwei Li, Guangqing Feng, Min Zhang, Xing Zhang, Jihong Lu, Chenyahui Feng, Fangshi Zhu. Oxymatrine attenuates TNBS-induced colinutis in rats through TLR9/Myd88/NF-κB signal pathway. Human & experimental toxicology. 2022 Jan; 41(?):9603271221078866. doi: 10.1177/09603271221078866. [PMID: 35290143]
  • Ryan C Ungaro, Erica J Brenner, Manasi Agrawal, Xian Zhang, Michael D Kappelman, Jean-Frederic Colombel. Impact of Medications on COVID-19 Outcomes in Inflammatory Bowel Disease: Analysis of More Than 6000 Patients From an International Registry. Gastroenterology. 2022 Jan; 162(1):316-319.e5. doi: 10.1053/j.gastro.2021.09.011. [PMID: 34529987]
  • Shicheng Sun, Changfa Guo, Taihong Gao, Dengzhen Ma, Xiangsheng Su, Qi Pang, Rui Zhang. Hypoxia Enhances Glioma Resistance to Sulfasalazine-Induced Ferroptosis by Upregulating SLC7A11 via PI3K/AKT/HIF-1α Axis. Oxidative medicine and cellular longevity. 2022; 2022(?):7862430. doi: 10.1155/2022/7862430. [PMID: 36439690]
  • Ruonan Ma, Ling Fang, Lei Chen, Xiaonan Wang, Jing Jiang, Lizeng Gao. Ferroptotic stress promotes macrophages against intracellular bacteria. Theranostics. 2022; 12(5):2266-2289. doi: 10.7150/thno.66663. [PMID: 35265210]
  • Morteza Ghasemnejad-Berenji. Can sulfasalazine as an old drug with immunomodulatory and anti-inflammatory effects be effective in COVID-19?. Journal of basic and clinical physiology and pharmacology. 2021 Dec; 33(1):113-115. doi: 10.1515/jbcpp-2021-0349. [PMID: 34855313]
  • González-Ramírez Adriana Estrella, González-Trujano María Eva, Hernandez-Leon Alberto, Valle-Dorado María Guadalupe, Carballo-Villalobos Azucena, Orozco-Suárez Sandra, Alvarado-Vásquez Noé, López-Muñoz Francisco Javier. Limonene from Agastache mexicana essential oil produces antinociceptive effects, gastrointestinal protection and improves experimental ulcerative colitis. Journal of ethnopharmacology. 2021 Nov; 280(?):114462. doi: 10.1016/j.jep.2021.114462. [PMID: 34324951]
  • M H Sanad, Syed Faheem Askari Rizvi, Ayman B Farag. Radiosynthesis and in silico bioevaluation of 131 I-Sulfasalazine as a highly selective radiotracer for imaging of ulcerative colitis. Chemical biology & drug design. 2021 11; 98(5):751-761. doi: 10.1111/cbdd.13929. [PMID: 34314572]
  • Asrin Ahmadi, Hossein Niknahad, Huifeng Li, Ali Mobasheri, Ram Kumar Manthari, Negar Azarpira, Khadijeh Mousavi, Bahman Khalvati, Yangfei Zhao, Jianyu Sun, Yuqi Zong, Mohammad Mehdi Ommati, Reza Heidari. The inhibition of NFкB signaling and inflammatory response as a strategy for blunting bile acid-induced hepatic and renal toxicity. Toxicology letters. 2021 Oct; 349(?):12-29. doi: 10.1016/j.toxlet.2021.05.012. [PMID: 34089816]
  • Ho Min Yong, Sung-Jo Park, Seong Ran Jeon, Heesu Park, Hyun Gun Kim, Tae Hee Lee, Junseok Park, Jin-Oh Kim, Joon Seong Lee, Bong Min Ko, Hyeon Jeong Goong, Suyeon Park. Endoscopy within 7 days after detecting high calprotectin levels can be useful for therapeutic decision-making in ulcerative colitis. Medicine. 2021 Aug; 100(34):e27065. doi: 10.1097/md.0000000000027065. [PMID: 34449501]
  • Satyaki Roy, Shehzad Z Sheikh, Terrence S Furey. A machine learning approach identifies 5-ASA and ulcerative colitis as being linked with higher COVID-19 mortality in patients with IBD. Scientific reports. 2021 08; 11(1):16522. doi: 10.1038/s41598-021-95919-2. [PMID: 34389789]
  • Jeon-Kyung Kim, Min Sun Choi, Jae-Young Kim, Jun Sang Yu, Jeong In Seo, Hye Hyun Yoo, Dong-Hyun Kim. Ginkgo biloba leaf extract suppresses intestinal human breast cancer resistance protein expression in mice: Correlation with gut microbiota. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2021 Aug; 140(?):111712. doi: 10.1016/j.biopha.2021.111712. [PMID: 34010745]
  • Pranavi Koppula, Li Zhuang, Boyi Gan. Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy. Protein & cell. 2021 08; 12(8):599-620. doi: 10.1007/s13238-020-00789-5. [PMID: 33000412]
  • Juan Zhang, Li Cao, Yu Sun, De-Gang Qing, Xiao-Qin Xu, Jun-Chi Wang, Jian-Yong Si, Ning Li. The Regulatory Effects of Licochalcone A on the Intestinal Epithelium and Gut Microbiota in Murine Colitis. Molecules (Basel, Switzerland). 2021 Jul; 26(14):. doi: 10.3390/molecules26144149. [PMID: 34299424]
  • Mohammad Shahidi-Dadras, Shaghayegh Shahrigharahkoshan, Esmat Yazdi, Alireza Fatemi, Zahra Mahboubi-Fooladi, Sahar Dadkhahfar. Sulfasalazine-Induced Toxic Epidermal Necrolysis: A Challenging Case During the COVID-19 Pandemic. Advanced emergency nursing journal. 2021 Jul; 43(3):194-197. doi: 10.1097/tme.0000000000000361. [PMID: 34397495]
  • Hong Shen, Shengsheng Zhang, Wenxia Zhao, Shunping Ren, Xiao Ke, Qinghua Gu, Zhipeng Tang, Jingri Xie, Suning Chen, Yan Chen, Jiandong Zou, Lu Zhang, Zhaofeng Shen, Kai Zheng, Yajun Liu, Peiqing Gu, Jiafei Cheng, Jingyi Hu, Lei Zhu. Randomised clinical trial: Efficacy and safety of Qing-Chang-Hua-Shi granules in a multicenter, randomized, and double-blind clinical trial of patients with moderately active ulcerative colitis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2021 Jul; 139(?):111580. doi: 10.1016/j.biopha.2021.111580. [PMID: 33857914]
  • Namshik Han, Woochang Hwang, Konstantinos Tzelepis, Patrick Schmerer, Eliza Yankova, Méabh MacMahon, Winnie Lei, Nicholas M Katritsis, Anika Liu, Ulrike Felgenhauer, Alison Schuldt, Rebecca Harris, Kathryn Chapman, Frank McCaughan, Friedemann Weber, Tony Kouzarides. Identification of SARS-CoV-2-induced pathways reveals drug repurposing strategies. Science advances. 2021 06; 7(27):. doi: 10.1126/sciadv.abh3032. [PMID: 34193418]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Yuhua Li, Yang Sun, Fanrong Diao, Yiming Ruan, Gui'e Chen, Tianle Tang, Yongsheng Liu, Huiping Zhou, Wenming Lin, Mingzhi Dong, Tieming Liu, Qibing Mei, De Cai. Jiaolong capsule protects SD rats against 2,4,6-trinitrobenzene sulfonic acid induced colitis. Journal of ethnopharmacology. 2021 Apr; 269(?):113716. doi: 10.1016/j.jep.2020.113716. [PMID: 33352238]
  • Fernando Rizzello, Carlo Calabrese, Marco Salice, Lucia Calandrini, Hana Privitera, Laura Melotti, Giulia Peruzzi, Nikolas Dussias, Andrea Belluzzi, Eleonora Scaioli, Anastasio Decorato, Antonio Siniscalchi, Eleonora Filippone, Silvio Laureti, Matteo Rottoli, Gilberto Poggioli, Paolo Gionchetti. COVID-19 in IBD: The experience of a single tertiary IBD center. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver. 2021 03; 53(3):271-276. doi: 10.1016/j.dld.2020.12.012. [PMID: 33451910]
  • Jangmi Choi, Min-Ho Park, Seok-Ho Shin, Jin-Ju Byeon, Byeong Ill Lee, Yuri Park, Young G Shin. Quantification and Metabolite Identification of Sulfasalazine in Mouse Brain and Plasma Using Quadrupole-Time-of-Flight Mass Spectrometry. Molecules (Basel, Switzerland). 2021 Feb; 26(4):. doi: 10.3390/molecules26041179. [PMID: 33671835]
  • Hilda Amekyeh, Nashiru Billa. Lyophilized Drug-Loaded Solid Lipid Nanoparticles Formulated with Beeswax and Theobroma Oil. Molecules (Basel, Switzerland). 2021 Feb; 26(4):. doi: 10.3390/molecules26040908. [PMID: 33572168]
  • Erica J Brenner, Bénédicte Pigneur, Gili Focht, Xian Zhang, Ryan C Ungaro, Jean-Frederic Colombel, Dan Turner, Michael D Kappelman, Frank M Ruemmele. Benign Evolution of SARS-Cov2 Infections in Children With Inflammatory Bowel Disease: Results From Two International Databases. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2021 02; 19(2):394-396.e5. doi: 10.1016/j.cgh.2020.10.010. [PMID: 33059040]
  • Sindy N Balconi, Natane T Lopes, Laura Luzzatto, Renan R Bonamigo. Detection of SARS-CoV-2 in a case of DRESS by sulfasalazine: could there be a relationship with clinical importance?. International journal of dermatology. 2021 Jan; 60(1):125-126. doi: 10.1111/ijd.15316. [PMID: 33231286]
  • J Novo de Matos, A Redondo Sendino, A Pozo Teruel, J I Redondo Sendino. [DRESS syndrome simulating coronavirus 2019-NcoV disease]. Semergen. 2021 Jan; 47(1):56-58. doi: 10.1016/j.semerg.2020.05.012. [PMID: 32507709]
  • Yasin Orooji, Sobhan Mortazavi-Derazkola, Seyedeh Masoumeh Ghoreishi, Mahnaz Amiri, Masoud Salavati-Niasari. Mesopourous Fe3O4@SiO2-hydroxyapatite nanocomposite: Green sonochemical synthesis using strawberry fruit extract as a capping agent, characterization and their application in sulfasalazine delivery and cytotoxicity. Journal of hazardous materials. 2020 12; 400(?):123140. doi: 10.1016/j.jhazmat.2020.123140. [PMID: 32563904]
  • Yves-Marie Pers, Guillaume Padern. Revisiting the cardiovascular risk of hydroxychloroquine in RA. Nature reviews. Rheumatology. 2020 12; 16(12):671-672. doi: 10.1038/s41584-020-00521-x. [PMID: 32999492]
  • Narjes Saheb Sharif-Askari, Fatemeh Saheb Sharif-Askari, Bushra Mdkhana, Saba Al Heialy, Elaref Ratemi, Malak Alghamdi, Salah Abusnana, Tarek Kashour, Qutayba Hamid, Rabih Halwani. Effect of common medications on the expression of SARS-CoV-2 entry receptors in liver tissue. Archives of toxicology. 2020 12; 94(12):4037-4041. doi: 10.1007/s00204-020-02869-1. [PMID: 32808185]
  • Andrew D Foers, Alexandra L Garnham, Gordon K Smyth, Susanna M Proudman, Lesley Cheng, Andrew F Hill, Ken C Pang, Ian P Wicks. Circulating Small Noncoding RNA Biomarkers of Response to Triple Disease-modifying Antirheumatic Drug Therapy in White Women With Early Rheumatoid Arthritis. The Journal of rheumatology. 2020 12; 47(12):1746-1751. doi: 10.3899/jrheum.191012. [PMID: 32541082]
  • Mario-Livio Jeličić, Edvin Brusač, Daniela Amidžić Klarić, Biljana Nigović, Nikša Turk, Ana Mornar. A chromatographic approach to development of 5-aminosalicylate/folic acid fixed-dose combinations for treatment of Crohn's disease and ulcerative colitis. Scientific reports. 2020 11; 10(1):20838. doi: 10.1038/s41598-020-77654-2. [PMID: 33257796]
  • Zheng Wang, Yanni Liang, Jingao Yu, Dongbo Zhang, Langlang Ren, Zhen Zhang, Yanru Liu, Xue Wu, Li Liu, Zhishu Tang. Guchang Zhixie Wan protects mice against dextran sulfate sodium-induced colitis through modulating the gut microbiota in colon. Journal of ethnopharmacology. 2020 Oct; 260(?):112991. doi: 10.1016/j.jep.2020.112991. [PMID: 32442592]
  • Michael R Duff, Scott A Gabel, Lars C Pedersen, Eugene F DeRose, Juno M Krahn, Elizabeth E Howell, Robert E London. The Structural Basis for Nonsteroidal Anti-Inflammatory Drug Inhibition of Human Dihydrofolate Reductase. Journal of medicinal chemistry. 2020 08; 63(15):8314-8324. doi: 10.1021/acs.jmedchem.0c00546. [PMID: 32658475]
  • Erica J Brenner, Ryan C Ungaro, Richard B Gearry, Gilaad G Kaplan, Michele Kissous-Hunt, James D Lewis, Siew C Ng, Jean-Francois Rahier, Walter Reinisch, Frank M Ruemmele, Flavio Steinwurz, Fox E Underwood, Xian Zhang, Jean-Frederic Colombel, Michael D Kappelman. Corticosteroids, But Not TNF Antagonists, Are Associated With Adverse COVID-19 Outcomes in Patients With Inflammatory Bowel Diseases: Results From an International Registry. Gastroenterology. 2020 08; 159(2):481-491.e3. doi: 10.1053/j.gastro.2020.05.032. [PMID: 32425234]
  • Martina Maria Capelletti, Hana Manceau, Hervé Puy, Katell Peoc'h. Ferroptosis in Liver Diseases: An Overview. International journal of molecular sciences. 2020 Jul; 21(14):. doi: 10.3390/ijms21144908. [PMID: 32664576]
  • Caroline M Joyce, Audrey Melvin, Paula M O'Shea, Seán J Costelloe, Domhnall J O'Halloran. Case report of a phantom pheochromocytoma. Biochemia medica. 2020 Jun; 30(2):021003. doi: 10.11613/bm.2020.021003. [PMID: 32550819]
  • Rasool Pelalak, Reza Alizadeh, Eslam Ghareshabani. Enhanced heterogeneous catalytic ozonation of pharmaceutical pollutants using a novel nanostructure of iron-based mineral prepared via plasma technology: A comparative study. Journal of hazardous materials. 2020 06; 392(?):122269. doi: 10.1016/j.jhazmat.2020.122269. [PMID: 32078970]
  • Bo Dou, Wenji Hu, Minkai Song, Robert J Lee, Xiaoyu Zhang, Di Wang. Anti-inflammation of Erianin in dextran sulphate sodium-induced ulcerative colitis mice model via collaborative regulation of TLR4 and STAT3. Chemico-biological interactions. 2020 Jun; 324(?):109089. doi: 10.1016/j.cbi.2020.109089. [PMID: 32272095]
  • Wen-Jun Liao, Feng-Jun Song, Hai-Fei Liu. Effects of sulfasalazine combined with moxibustion methods on patients with cold-dampness obstruction type ankylosing spondylitis. Pakistan journal of pharmaceutical sciences. 2020 May; 33(3(Special)):1367-1371. doi: . [PMID: 33361024]
  • Maha M Abdelrahman, Neven M Habib, Aml A Emam, Hamada M Mahmoud, Nada S Abdelwhab. Chromatographic determination of sulfasalazine and its active metabolites: greenness assessment and application to spiked human plasma. Biomedical chromatography : BMC. 2020 Apr; 34(4):e4804. doi: 10.1002/bmc.4804. [PMID: 32012304]
  • Frauke Antoni, Manuel Bause, Matthias Scholler, Stefanie Bauer, Simone A Stark, Scott M Jackson, Ioannis Manolaridis, Kaspar P Locher, Burkhard König, Armin Buschauer, Günther Bernhardt. Tariquidar-related triazoles as potent, selective and stable inhibitors of ABCG2 (BCRP). European journal of medicinal chemistry. 2020 Apr; 191(?):112133. doi: 10.1016/j.ejmech.2020.112133. [PMID: 32105979]
  • Xiaoguang Liu, Kellen Olszewski, Yilei Zhang, Esther W Lim, Jiejun Shi, Xiaoshan Zhang, Jie Zhang, Hyemin Lee, Pranavi Koppula, Guang Lei, Li Zhuang, M James You, Bingliang Fang, Wei Li, Christian M Metallo, Masha V Poyurovsky, Boyi Gan. Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer. Nature cell biology. 2020 04; 22(4):476-486. doi: 10.1038/s41556-020-0496-x. [PMID: 32231310]
  • Im-Sook Song, Hyeon-Uk Jeong, Min-Koo Choi, Mihwa Kwon, Yongho Shin, Jeong Han Kim, Hye-Suk Lee. Interactions between cyazofamid and human drug transporters. Journal of biochemical and molecular toxicology. 2020 Apr; 34(4):e22459. doi: 10.1002/jbt.22459. [PMID: 32003934]
  • Daiha Shin, Jaewang Lee, Ji Hyeon You, Doyeon Kim, Jong-Lyel Roh. Dihydrolipoamide dehydrogenase regulates cystine deprivation-induced ferroptosis in head and neck cancer. Redox biology. 2020 02; 30(?):101418. doi: 10.1016/j.redox.2019.101418. [PMID: 31931284]
  • Yuji Otsuki, Juntaro Yamasaki, Kentaro Suina, Shogo Okazaki, Naoyoshi Koike, Hideyuki Saya, Osamu Nagano. Vasodilator oxyfedrine inhibits aldehyde metabolism and thereby sensitizes cancer cells to xCT-targeted therapy. Cancer science. 2020 Jan; 111(1):127-136. doi: 10.1111/cas.14224. [PMID: 31692172]
  • Dan Huang, Jian Liu, Rui-Kai Zong, Lei Wan. [Huangqin Qingre Chubi Capsules in improving oxidative stress of patients with ankylosing spondylitis via activating PPARγ mediated AMPK/FOXO3a pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2020 Jan; 45(2):451-456. doi: 10.19540/j.cnki.cjcmm.20190619.501. [PMID: 32237331]
  • Jaewang Lee, Ji Hyeon You, Daiha Shin, Jong-Lyel Roh. Inhibition of Glutaredoxin 5 predisposes Cisplatin-resistant Head and Neck Cancer Cells to Ferroptosis. Theranostics. 2020; 10(17):7775-7786. doi: 10.7150/thno.46903. [PMID: 32685019]
  • Masahide Fujita, Débora da Luz Scheffer, Bruna Lenfers Turnes, Shane J F Cronin, Alban Latrémolière, Michael Costigan, Clifford J Woolf, Alexandra Latini, Nick A Andrews. Sepiapterin Reductase Inhibition Leading to Selective Reduction of Inflammatory Joint Pain in Mice and Increased Urinary Sepiapterin Levels in Humans and Mice. Arthritis & rheumatology (Hoboken, N.J.). 2020 01; 72(1):57-66. doi: 10.1002/art.41060. [PMID: 31350812]
  • Guosheng Lin, Minyao Li, Nan Xu, Xiaoli Wu, Jingjing Liu, Yulin Wu, Qian Zhang, Jian Cai, Changjun Gao, Ziren Su. Anti-Inflammatory Effects of Heritiera littoralis Fruits on Dextran Sulfate Sodium- (DSS-) Induced Ulcerative Colitis in Mice by Regulating Gut Microbiota and Suppressing NF-κB Pathway. BioMed research international. 2020; 2020(?):8893621. doi: 10.1155/2020/8893621. [PMID: 33354574]
  • Nageh Ahmed El-Mahdy, Dina Ali Saleh, Magdy Salah Amer, Sally El-Sayed Abu-Risha. Role of allopurinol and febuxostat in the amelioration of dextran-induced colitis in rats. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2020 Jan; 141(?):105116. doi: 10.1016/j.ejps.2019.105116. [PMID: 31654756]
  • Xueting Lang, Michael D Green, Weimin Wang, Jiali Yu, Jae Eun Choi, Long Jiang, Peng Liao, Jiajia Zhou, Qiang Zhang, Ania Dow, Anjali L Saripalli, Ilona Kryczek, Shuang Wei, Wojciech Szeliga, Linda Vatan, Everett M Stone, George Georgiou, Marcin Cieslik, Daniel R Wahl, Meredith A Morgan, Arul M Chinnaiyan, Theodore S Lawrence, Weiping Zou. Radiotherapy and Immunotherapy Promote Tumoral Lipid Oxidation and Ferroptosis via Synergistic Repression of SLC7A11. Cancer discovery. 2019 12; 9(12):1673-1685. doi: 10.1158/2159-8290.cd-19-0338. [PMID: 31554642]
  • João Paulo Bizarro Lopes, Luana Silva, Marco Antonio Ceschi, Diogo Seibert Lüdtke, Aline Rigon Zimmer, Thais Carine Ruaro, Rafael Ferreira Dantas, Cristiane Martins Cardoso de Salles, Floriano Paes Silva-Jr, Mario Roberto Senger, Gisele Barbosa, Lídia Moreira Lima, Isabella Alvim Guedes, Laurent Emmanuel Dardenne. Synthesis of new lophine-carbohydrate hybrids as cholinesterase inhibitors: cytotoxicity evaluation and molecular modeling. MedChemComm. 2019 Dec; 10(12):2089-2101. doi: 10.1039/c9md00358d. [PMID: 32904099]
  • Xian Cheng, Jian-Liang Zhou, Zi-Qi Shi, Ying-Hao Yin, Jian-Qun Liu, Han-Xiang Chen, Ping Li, Li-Fang Liu, Gui-Zhong Xin. Ammonium fluoride-induced stabilization for anion attachment mass spectrometry: Facilitating the pseudotargeted profiling of bile acids submetabolome. Analytica chimica acta. 2019 Nov; 1081(?):120-130. doi: 10.1016/j.aca.2019.07.006. [PMID: 31446949]
  • Paloma Oliveira Antonino de Assis, Gerlane Coelho Bernardo Guerra, Daline Fernandes de Souza Araújo, Leylliane de Fátima Leal Interaminense de Andrade, Aurigena Antunes de Araújo, Raimundo Fernandes de Araújo, Thaís Gomes de Carvalho, Maria de Fátima Vanderlei de Souza, Graciele da Silva Campelo Borges, Marcos Dos Santos Lima, Fernanda Rodrigues Leite Rolim, Raphaela Araújo Veloso Rodrigues, Rita de Cássia Ramos do Egypto Queiroga. Intestinal anti-inflammatory activity of xique-xique (Pilosocereus gounellei A. Weber ex K. Schum. Bly. Ex Rowl) juice on acetic acid-induced colitis in rats. Food & function. 2019 Nov; 10(11):7275-7290. doi: 10.1039/c9fo00920e. [PMID: 31621721]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Mohamed A Morsy, Sumeet Gupta, Anroop B Nair, Katharigatta N Venugopala, Khaled Greish, Mahmoud El-Daly. Protective Effect of Spirulina platensis Extract against Dextran-Sulfate-Sodium-Induced Ulcerative Colitis in Rats. Nutrients. 2019 Sep; 11(10):. doi: 10.3390/nu11102309. [PMID: 31569451]
  • Wesam M El-Koussi, Noha N Atia, Gamal A Saleh, Nevin Hammam. Innovative HPTLC method for simultaneous determination of ternary mixture of certain DMARDs in real samples of rheumatoid arthritis patients: an application of quality by design approach. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2019 Aug; 1124(?):135-145. doi: 10.1016/j.jchromb.2019.05.038. [PMID: 31200245]
  • Yuti Yin, Lei Ye, Zhongbao Niu, Wenhui Fang. Anti-inflammatory effects of Vicenin-2 on dextran sulfate sodium-induced colitis in mice. Drug development research. 2019 08; 80(5):546-555. doi: 10.1002/ddr.21529. [PMID: 30972795]
  • Mahima Sharma, Dharmendra Arya, Kiran Bhagour, Radhey S Gupta. Modulatory effects of methanolic fruit fraction of Pedalium murex on sulphasalazine-induced male reproductive disruption. Andrologia. 2019 Mar; 51(2):e13190. doi: 10.1111/and.13190. [PMID: 30430603]
  • Hamidreza Ahmadpour, Seyed Mohamadreza Milani Hosseini. A solid-phase luminescence sensor based on molecularly imprinted polymer-CdSeS/ZnS quantum dots for selective extraction and detection of sulfasalazine in biological samples. Talanta. 2019 Mar; 194(?):534-541. doi: 10.1016/j.talanta.2018.10.053. [PMID: 30609569]
  • Xiaohua Jiang, Dongmiao Qin, Guichun Mo, Jinsu Feng, Chunhe Yu, Weiming Mo, Biyang Deng. Ginkgo leaf-based synthesis of nitrogen-doped carbon quantum dots for highly sensitive detection of salazosulfapyridine in mouse plasma. Journal of pharmaceutical and biomedical analysis. 2019 Feb; 164(?):514-519. doi: 10.1016/j.jpba.2018.11.025. [PMID: 30453158]
  • N A Soliman, W A Keshk, F H Rizk, M A Ibrahim. The possible ameliorative effect of simvastatin versus sulfasalazine on acetic acid induced ulcerative colitis in adult rats. Chemico-biological interactions. 2019 Jan; 298(?):57-65. doi: 10.1016/j.cbi.2018.11.002. [PMID: 30408459]
  • Zhong-Hua Tian, Xin-Yi Wang, Yu-Fei Zhang, Yuan-Sheng Tian. [Efficacy of herb-separated moxibustion combined with sulfasalazine enteric-coated tablets for ankylosing spondylitis with cold-dampness obstruction type]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. 2019 Jan; 39(1):44-8. doi: 10.13703/j.0255-2930.2019.01.010. [PMID: 30672255]
  • Xiaojun Xia, Xiaoping Fan, Mingyi Zhao, Ping Zhu. The Relationship between Ferroptosis and Tumors: A Novel Landscape for Therapeutic Approach. Current gene therapy. 2019; 19(2):117-124. doi: 10.2174/1566523219666190628152137. [PMID: 31264548]
  • Yusuke Morinaga, Ichiro Abe, Tomohiro Minamikawa, Yusuke Ueda, Kouhei Nii, Kimiya Sakamoto, Ritsurou Inoue, Takafumi Mitsutake, Hayatsura Hanada, Jun Tsugawa, Kanako Kurihara, Toshio Higashi. A case of drug-induced hypersensitivity syndrome induced by salazosulfapyridine combined with SIADH caused by interstitial pneumonia. Drug discoveries & therapeutics. 2019; 13(4):232-238. doi: 10.5582/ddt.2019.01045. [PMID: 31534076]
  • Kentaro Suina, Kenji Tsuchihashi, Juntaro Yamasaki, Shohei Kamenori, Subaru Shintani, Yuki Hirata, Shogo Okazaki, Oltea Sampetrean, Eishi Baba, Koichi Akashi, Yoichiro Mitsuishi, Fumiyuki Takahashi, Kazuhisa Takahashi, Hideyuki Saya, Osamu Nagano. Epidermal growth factor receptor promotes glioma progression by regulating xCT and GluN2B-containing N-methyl-d-aspartate-sensitive glutamate receptor signaling. Cancer science. 2018 Dec; 109(12):3874-3882. doi: 10.1111/cas.13826. [PMID: 30298963]
  • Rohan Moniruzzaman, Mati Ur Rehman, Qing-Li Zhao, Paras Jawaid, Yohei Mitsuhashi, Shuichi Imaue, Kumiko Fujiwara, Ryohei Ogawa, Kei Tomihara, Jun-Ichi Saitoh, Kyo Noguchi, Takashi Kondo, Makoto Noguchi. Roles of intracellular and extracellular ROS formation in apoptosis induced by cold atmospheric helium plasma and X-irradiation in the presence of sulfasalazine. Free radical biology & medicine. 2018 12; 129(?):537-547. doi: 10.1016/j.freeradbiomed.2018.10.434. [PMID: 30355525]
  • Xiaofei Liu, Xiuting Yu, Xiaofei Xu, Xiaojun Zhang, Xuewu Zhang. The protective effects of Poria cocos-derived polysaccharide CMP33 against IBD in mice and its molecular mechanism. Food & function. 2018 Nov; 9(11):5936-5949. doi: 10.1039/c8fo01604f. [PMID: 30378628]
  • Kasirawat Sawangrat, Masaki Morishita, Kosuke Kusamori, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamoto. Effects of Various Pharmaceutical Excipients on the Intestinal Transport and Absorption of Sulfasalazine, a Typical Substrate of Breast Cancer Resistance Protein Transporter. Journal of pharmaceutical sciences. 2018 11; 107(11):2946-2956. doi: 10.1016/j.xphs.2018.07.011. [PMID: 30053556]
  • B O Ajayi, I A Adedara, E O Farombi. Protective mechanisms of 6-gingerol in dextran sulfate sodium-induced chronic ulcerative colitis in mice. Human & experimental toxicology. 2018 Oct; 37(10):1054-1068. doi: 10.1177/0960327117751235. [PMID: 29350052]
  • Eun Hye Kim, Daiha Shin, Jaewang Lee, Ah Ra Jung, Jong-Lyel Roh. CISD2 inhibition overcomes resistance to sulfasalazine-induced ferroptotic cell death in head and neck cancer. Cancer letters. 2018 09; 432(?):180-190. doi: 10.1016/j.canlet.2018.06.018. [PMID: 29928961]
  • Lea Wagmann, Hans H Maurer, Markus R Meyer. Inhibition and stimulation of the human breast cancer resistance protein as in vitro predictor of drug-drug interactions of drugs of abuse. Archives of toxicology. 2018 09; 92(9):2875-2884. doi: 10.1007/s00204-018-2276-y. [PMID: 30083819]