ofloxacin (BioDeep_00000270840)
Main id: BioDeep_00000001367
natural product
代谢物信息卡片
ofloxacin
化学式: C18H20FN3O4 (361.1438)
中文名称: 阿莫西林杂质I, 氧氟沙星
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1COC2=C(N3CCN(C)CC3)C(F)=CC4=C2N1C=C(C(O)=O)C4=O
InChI: InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)
描述信息
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01M - Quinolone antibacterials > J01MA - Fluoroquinolones
D004791 - Enzyme Inhibitors > D065607 - Cytochrome P-450 Enzyme Inhibitors > D065609 - Cytochrome P-450 CYP1A2 Inhibitors
D000970 - Antineoplastic Agents > D059003 - Topoisomerase Inhibitors > D059005 - Topoisomerase II Inhibitors
S - Sensory organs > S01 - Ophthalmologicals > S01A - Antiinfectives > S01AE - Fluoroquinolones
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D024841 - Fluoroquinolones
S - Sensory organs > S02 - Otologicals > S02A - Antiinfectives > S02AA - Antiinfectives
C254 - Anti-Infective Agent > C258 - Antibiotic > C795 - Quinolone Antibiotic
CASMI2013 Challenge_16 MS2 data, retention time = 3.7 min
CASMI2013 Challenge_16 MS1 data, retention time = 3.7 min
同义名列表
数据库引用编号
23 个数据库交叉引用编号
- ChEBI: CHEBI:194135
- ChEBI: CHEBI:7731
- KEGG: C07321
- KEGGdrug: D00453
- PubChem: 4583
- DrugBank: DB01165
- ChEMBL: CHEMBL4
- MeSH: Ofloxacin
- CAS: 1261398-33-7
- CAS: 82419-36-1
- CAS: 83380-47-6
- MoNA: CCMSLIB00000081724
- MoNA: MSJ00034
- MoNA: MSJ00033
- MoNA: MSJ00032
- MoNA: MSJ00031
- MoNA: MSJ00030
- PMhub: MS000000401
- PubChem: 9529
- NIKKAJI: J244.886F
- RefMet: Ofloxacin
- KNApSAcK: 7731
- LOTUS: LTS0061799
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
5 个相关的物种来源信息
- 2 - Bacteria: LTS0061799
- 1883 - Streptomyces: LTS0061799
- 1912 - Streptomyces hygroscopicus: 10.1021/NP400145U
- 1912 - Streptomyces hygroscopicus: LTS0061799
- 2062 - Streptomycetaceae: LTS0061799
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Xiaoying Mu, Songhe Zhang, Jianhui Lu, Yangrui Huang, Jianghao Ji. Fate and removal of fluoroquinolone antibiotics in mesocosmic wetlands: Impact on wetland performance, resistance genes and microbial communities.
Journal of hazardous materials.
2024 May; 470(?):133740. doi:
10.1016/j.jhazmat.2024.133740. [PMID: 38569335] - Elizabeth Holton, Carla Louw, Edward Archer, Tobias Louw, Gideon Wolfaardt, Barbara Kasprzyk-Hordern. Quantifying community-wide antibiotic usage via urban water fingerprinting: Focus on contrasting resource settings in South Africa.
Water research.
2023 May; 240(?):120110. doi:
10.1016/j.watres.2023.120110. [PMID: 37247434] - Lei Zhao, Zhenzhen Han, Mengying Zhou, Cong Lyu, Yu Li. Field measures of strengthen plant-microbial remediation of PAHs-FQs compound pollution.
Environmental science and pollution research international.
2023 May; ?(?):. doi:
10.1007/s11356-023-27618-6. [PMID: 37202637] - Youshuai Fang, Ying Liu, Jian Zhang. Mechanisms for the increase in lipid production in cyanobacteria during the degradation of antibiotics.
Environmental pollution (Barking, Essex : 1987).
2023 Apr; 322(?):121171. doi:
10.1016/j.envpol.2023.121171. [PMID: 36736559] - Xiaopeng Hu, Sanqi An, Jiemei Chu, Bingyu Liang, Yanyan Liao, Junjun Jiang, Yao Lin, Li Ye, Hao Liang. Potential Inhibitors of Monkeypox Virus Revealed by Molecular Modeling Approach to Viral DNA Topoisomerase I.
Molecules (Basel, Switzerland).
2023 Feb; 28(3):. doi:
10.3390/molecules28031444. [PMID: 36771105] - Fengjiao Zhang, Xufeng Mao, Xiuhua Song, Hongyan Yu, Jinlu Yan, Dongsheng Kong, Yinlong Liu, Naixin Yao, Shilin Yang, Shunbang Xie, Haichuan Ji, Huakun Zhou. Ecological Risks of Antibiotics in Urban Wetlands on the Qinghai-Tibet Plateau, China.
International journal of environmental research and public health.
2023 01; 20(3):. doi:
10.3390/ijerph20031735. [PMID: 36767103] - Zhihuan Zhang, Xuena Liu, Na Li, Bili Cao, Tingting Huang, Ping Li, Shuqin Liu, Yongzhi Zhang, Kun Xu. Effect of ofloxacin levels on growth, photosynthesis and chlorophyll fluorescence kinetics in tomato.
Plant physiology and biochemistry : PPB.
2023 Jan; 194(?):374-382. doi:
10.1016/j.plaphy.2022.11.029. [PMID: 36470152] - Kathryn R Hayden, Matthew Jones, Kyle R Elkin, Michael J Shreve, William Irvin Clees, Shirley Clark, Michael L Mashtare, Tamie L Veith, Herschel A Elliott, John E Watson, Justin Silverman, Thomas L Richard, Andrew F Read, Heather E Preisendanz. Impacts of the COVID-19 pandemic on pharmaceuticals in wastewater treated for beneficial reuse: Two case studies in central Pennsylvania.
Journal of environmental quality.
2022 Sep; 51(5):1066-1082. doi:
10.1002/jeq2.20398. [PMID: 35919971] - Shasank S Swain, Sunil S Rout, Alaka Sahoo, Sunday O Oyedemi, Tahziba Hussain. Antituberculosis, antioxidant and cytotoxicity profiles of quercetin: a systematic and cost-effective in silico and in vitro approach.
Natural product research.
2022 Sep; 36(18):4763-4767. doi:
10.1080/14786419.2021.2008387. [PMID: 34854322] - Xiaocui Wu, Guangkun Tan, Jinghui Yang, Yinjuan Guo, Chengchen Huang, Wei Sha, Fangyou Yu. Prediction of Mycobacterium tuberculosis drug resistance by nucleotide MALDI-TOF-MS.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.
2022 Aug; 121(?):47-54. doi:
10.1016/j.ijid.2022.04.061. [PMID: 35523300] - Izabella Kośka, Krystian Purgat, Paweł Kubalczyk. Simple, fast and reliable CE method for simultaneous determination of ciprofloxacin and ofloxacin in human urine.
Scientific reports.
2022 05; 12(1):7729. doi:
10.1038/s41598-022-11747-y. [PMID: 35545693] - Xiaocui Wu, Guangkun Tan, Wei Sha, Haican Liu, Jinghui Yang, Yinjuan Guo, Xin Shen, Zheyuan Wu, Hongbo Shen, Fangyou Yu. Use of Whole-Genome Sequencing to Predict Mycobacterium tuberculosis Complex Drug Resistance from Early Positive Liquid Cultures.
Microbiology spectrum.
2022 04; 10(2):e0251621. doi:
10.1128/spectrum.02516-21. [PMID: 35311541] - Qingmei Tian, Jicun Qian, Yuhui Zhao, Dadong Guo, Jike Song, Hongsheng Bi. Rabbit-derived human Thelazia callipaeda infection: a case report.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.
2022 Mar; 116(?):355-357. doi:
10.1016/j.ijid.2022.01.014. [PMID: 35017111] - Chia-Ying Ho, Shy-Chyi Chin, Chih-Yu Hu, Shih-Lung Chen. The necessity and effect of prophylactic quinolone ear drops after ventilation tube insertion for otitis media with effusion.
American journal of otolaryngology.
2022 Jan; 43(1):103266. doi:
10.1016/j.amjoto.2021.103266. [PMID: 34757314] - Zhihuan Zhang, Xuena Liu, Yao Lv, Na Li, Kun Xu. Grafting resulting in alleviating tomato plant oxidative damage caused by high levels of ofloxacin.
Environmental pollution (Barking, Essex : 1987).
2021 Oct; 286(?):117331. doi:
10.1016/j.envpol.2021.117331. [PMID: 34126516] - Lingtong Li, Jiaxi He, Zhiwei Gan, Ping Yang. Occurrence and fate of antibiotics and heavy metals in sewage treatment plants and risk assessment of reclaimed water in Chengdu, China.
Chemosphere.
2021 Jun; 272(?):129730. doi:
10.1016/j.chemosphere.2021.129730. [PMID: 35534953] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - I Sartini, B Łebkowska-Wieruszewska, A Sitovs, A Lisowski, A Poapolathep, M Giorgi. Levofloxacin pharmacokinetics and tissue residue concentrations after oral administration in Bilgorajska geese.
British poultry science.
2021 Apr; 62(2):193-198. doi:
10.1080/00071668.2020.1842855. [PMID: 33121260] - Xuena Liu, Yao Lv, Song Gao, Kun Xu. Ofloxacin induces etiolation in Welsh onion leaves.
Chemosphere.
2021 Mar; 267(?):128918. doi:
10.1016/j.chemosphere.2020.128918. [PMID: 33218729] - He Guo, Zhen Li, Siying Lin, Dongsheng Li, Nan Jiang, Huijuan Wang, Jiangang Han, Jie Li. Multi-catalysis induced by pulsed discharge plasma coupled with graphene-Fe3O4 nanocomposites for efficient removal of ofloxacin in water: Mechanism, degradation pathway and potential toxicity.
Chemosphere.
2021 Feb; 265(?):129089. doi:
10.1016/j.chemosphere.2020.129089. [PMID: 33261841] - Ogechukwu Calista Dozie-Nwakile, Nwakile Calistus Dozie, Uchendu Ikenna Kingsley, Okonkwo Francis Catherine, Onyemelukwe Ngozi Felicia. Effects of Kolaviron on Pneumonia-like Infection Induced in Albino Wistar Rats.
Anti-inflammatory & anti-allergy agents in medicinal chemistry.
2021; 20(2):219-227. doi:
10.2174/1871523019666200915085729. [PMID: 32933465] - Huma Mahmood, Ikram Ullah Khan, Muhammad Asif, Rizwan Ullah Khan, Sajid Asghar, Ikrima Khalid, Syed Haroon Khalid, Muhammad Irfan, Fauzia Rehman, Yasser Shahzad, Abid Mehmood Yousaf, Adnan Younus, Zahid Rasul Niazi, Muhammad Asim. In vitro and in vivo evaluation of gellan gum hydrogel films: Assessing the co impact of therapeutic oils and ofloxacin on wound healing.
International journal of biological macromolecules.
2021 Jan; 166(?):483-495. doi:
10.1016/j.ijbiomac.2020.10.206. [PMID: 33130262] - Wanling Cai, Xiulan Weng, Wei Zhang, Zuliang Chen. Green magnetic nanomaterial as antibiotic release vehicle: The release of pefloxacin and ofloxacin.
Materials science & engineering. C, Materials for biological applications.
2021 Jan; 118(?):111439. doi:
10.1016/j.msec.2020.111439. [PMID: 33255032] - Jiamin Xu, Xiaohui Liu, Yao Lv, Xiaochun Guo, Shaoyong Lu. Response of Cyperus involucratus to sulfamethoxazole and ofloxacin-contaminated environments: Growth physiology, transportation, and microbial community.
Ecotoxicology and environmental safety.
2020 Dec; 206(?):111332. doi:
10.1016/j.ecoenv.2020.111332. [PMID: 32980655] - Yu-Feng Zhou, Ping Liu, Shu-He Dai, Jian Sun, Ya-Hong Liu, Xiao-Ping Liao. In Vivo Pharmacodynamic Target Assessment of Antofloxacin against Streptococcus pneumoniae and Staphylococcus aureus in a Neutropenic Murine Pneumonia Model.
Antimicrobial agents and chemotherapy.
2020 11; 64(12):. doi:
10.1128/aac.01354-20. [PMID: 32928734] - Libin Yang, Li Ren, Xiaobo Tan, Huaqiang Chu, Jiabin Chen, Yalei Zhang, Xuefei Zhou. Removal of ofloxacin with biofuel production by oleaginous microalgae Scenedesmus obliquus.
Bioresource technology.
2020 Nov; 315(?):123738. doi:
10.1016/j.biortech.2020.123738. [PMID: 32659423] - Yayang Tian, Xiaoyu He, Hui Zhou, Xike Tian, Yulun Nie, Zhaoxin Zhou, Chao Yang, Yong Li. Efficient fenton-like degradation of ofloxacin over bimetallic Fe-Cu@Sepiolite composite.
Chemosphere.
2020 Oct; 257(?):127209. doi:
10.1016/j.chemosphere.2020.127209. [PMID: 32502736] - Li-Yu Liang, Ying-Chun He, Yun-Fei Li, Juan Yang, Feng-Yan Xu, Lu-Jin Li, Ji-Han Huang, Kun Wang, Qing-Shan Zheng. Relationship between antofloxacin concentration and QT prolongation and estimation of the possible false-positive rate.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2020 Oct; 130(?):110619. doi:
10.1016/j.biopha.2020.110619. [PMID: 32795925] - Yao Lv, Yanyan Li, Xiaohui Liu, Kun Xu. The tolerance mechanism and accumulation characteristics of Phragmites australis to sulfamethoxazole and ofloxacin.
Chemosphere.
2020 Aug; 253(?):126695. doi:
10.1016/j.chemosphere.2020.126695. [PMID: 32278902] - Xiaocui Wu, Rongliang Gao, Xin Shen, Yinjuan Guo, Jinghui Yang, Zheyuan Wu, Guangkun Tan, Hongxiu Wang, Fangyou Yu. Use of whole-genome sequencing to predict Mycobacterium tuberculosis drug resistance in Shanghai, China.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.
2020 Jul; 96(?):48-53. doi:
10.1016/j.ijid.2020.04.039. [PMID: 32339720] - Sharon Akinpelu, Abraham Ajayi, Stella I Smith, Adeyemi I Adeleye. Efflux pump activity, biofilm formation and antibiotic resistance profile of Klebsiella spp. isolated from clinical samples at Lagos University Teaching Hospital.
BMC research notes.
2020 May; 13(1):258. doi:
10.1186/s13104-020-05105-2. [PMID: 32456668] - Đorđe Tadić, Michal Gramblicka, Robert Mistrik, Cintia Flores, Benjamin Piña, Josep Maria Bayona. Elucidating biotransformation pathways of ofloxacin in lettuce (Lactuca sativa L).
Environmental pollution (Barking, Essex : 1987).
2020 May; 260(?):114002. doi:
10.1016/j.envpol.2020.114002. [PMID: 31991361] - Yushan Huang, Zuhong Zhang, Tianchun Hou, Jingfang Shi, Wenjie Huang, Zhao Bai, Danfeng Long, Xiaodan Huang, Shijuan Yan. Antibiotic burden of school children from Tibetan, Hui, and Han groups in the Qinghai-Tibetan Plateau.
PloS one.
2020; 15(2):e0229205. doi:
10.1371/journal.pone.0229205. [PMID: 32092096] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - B Rodenak-Kladniew, S Scioli Montoto, M L Sbaraglini, M Di Ianni, M E Ruiz, A Talevi, V A Alvarez, N Durán, G R Castro, G A Islan. Hybrid Ofloxacin/eugenol co-loaded solid lipid nanoparticles with enhanced and targetable antimicrobial properties.
International journal of pharmaceutics.
2019 Oct; 569(?):118575. doi:
10.1016/j.ijpharm.2019.118575. [PMID: 31356956] - M J Gallardo-Altamirano, P Maza-Márquez, N Montemurro, B Rodelas, F Osorio, C Pozo. Linking microbial diversity and population dynamics to the removal efficiency of pharmaceutically active compounds (PhACs) in an anaerobic/anoxic/aerobic (A2O) system.
Chemosphere.
2019 Oct; 233(?):828-842. doi:
10.1016/j.chemosphere.2019.06.017. [PMID: 31200141] - Vineet Singh, Bhawna Pandey, Surindra Suthar. Phytotoxicity and degradation of antibiotic ofloxacin in duckweed (Spirodela polyrhiza) system.
Ecotoxicology and environmental safety.
2019 Sep; 179(?):88-95. doi:
10.1016/j.ecoenv.2019.04.018. [PMID: 31026754] - Jianmin Li, Lijuan Zhao, Chanling Wei, Zhian Sun, Shanwen Zhao, Tianpei Cai, Bolin Gong. Preparation of restricted access media molecularly imprinted polymers for efficient separation and enrichment ofloxacin in bovine serum samples.
Journal of separation science.
2019 Aug; 42(15):2491-2499. doi:
10.1002/jssc.201900103. [PMID: 31106511] - Hussein M Eid, Mohammed H Elkomy, Shahira F El Menshawe, Heba F Salem. Development, Optimization, and In Vitro/In Vivo Characterization of Enhanced Lipid Nanoparticles for Ocular Delivery of Ofloxacin: the Influence of Pegylation and Chitosan Coating.
AAPS PharmSciTech.
2019 May; 20(5):183. doi:
10.1208/s12249-019-1371-6. [PMID: 31054011] - Kaifeng Yu, Chi Sun, Bo Zhang, Muhammad Hassan, Yiliang He. Size-dependent adsorption of antibiotics onto nanoparticles in a field-scale wastewater treatment plant.
Environmental pollution (Barking, Essex : 1987).
2019 May; 248(?):1079-1087. doi:
10.1016/j.envpol.2019.02.090. [PMID: 31091640] - Christina Vakh, Marcel Alaboud, Sofya Lebedinets, Andrey Bulatov. A rotating cotton-based disk packed with a cation-exchange resin: Separation of ofloxacin from biological fluids followed by chemiluminescence determination.
Talanta.
2019 May; 196(?):117-123. doi:
10.1016/j.talanta.2018.12.024. [PMID: 30683340] - Wei Zhang, Shichun Lun, Ling-Ling Liu, Shiqi Xiao, Guanfu Duan, Hendra Gunosewoyo, Fan Yang, Jie Tang, William R Bishai, Li-Fang Yu. Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis. Part II.
Journal of medicinal chemistry.
2019 04; 62(7):3575-3589. doi:
10.1021/acs.jmedchem.9b00010. [PMID: 30875203] - Xinnan Tong, Xinze Wang, Xiaojuan He, Yanming Sui, Jian Shen, Jimeng Feng. Effects of antibiotics on nitrogen uptake of four wetland plant species grown under hydroponic culture.
Environmental science and pollution research international.
2019 Apr; 26(11):10621-10630. doi:
10.1007/s11356-019-04184-4. [PMID: 30762179] - Chaitanya Sarangapani, Dana Ziuzina, Patrice Behan, Daniela Boehm, Brendan F Gilmore, P J Cullen, Paula Bourke. Degradation kinetics of cold plasma-treated antibiotics and their antimicrobial activity.
Scientific reports.
2019 03; 9(1):3955. doi:
10.1038/s41598-019-40352-9. [PMID: 30850645] - Xue Xiao, Jia Wu, Zhenqun Li, Li Jia. Enantioseparation and sensitive analysis of ofloxacin by poly(3,4-dihydroxyphenylalanine) functionalized magnetic nanoparticles-based solid phase extraction in combination with on-line concentration capillary electrophoresis.
Journal of chromatography. A.
2019 Feb; 1587(?):14-23. doi:
10.1016/j.chroma.2018.11.026. [PMID: 30473108] - Anderson Martin Santos, Ademar Wong, Fernando Campanhã Vicentini, Orlando Fatibello-Filho. Simultaneous voltammetric sensing of levodopa, piroxicam, ofloxacin and methocarbamol using a carbon paste electrode modified with graphite oxide and β-cyclodextrin.
Mikrochimica acta.
2019 02; 186(3):174. doi:
10.1007/s00604-019-3296-x. [PMID: 30771008] - Dinesh K Patel, Sandeep Mittal, Nimisha Tiwari, Anil K Maurya, Dhirendra Singh, Alok K Pandey, Anirban Pal. Plasmodium-Salmonella Coinfection Induces Intense Inflammatory Response, Oxidative Stress, and Liver Damage: A Mice Model Study for Therapeutic Strategy.
Shock (Augusta, Ga.).
2018 12; 50(6):741-749. doi:
10.1097/shk.0000000000001111. [PMID: 29394238] - Xuedong Wang, Yuansi Zheng, Yan Ma, Liyang Du, Fangyu Chu, Haidong Gu, Randy A Dahlgren, Yanyan Li, Huili Wang. Lipid metabolism disorder induced by up-regulation of miR-125b and miR-144 following β-diketone antibiotic exposure to F0-zebrafish (Danio rerio).
Ecotoxicology and environmental safety.
2018 Nov; 164(?):243-252. doi:
10.1016/j.ecoenv.2018.08.027. [PMID: 30121499] - Dengmiao Cheng, Xinhui Liu, Jinpeng Li, Yao Feng, Juan Wang, Zhaojun Li. Effects of the natural colloidal particles from one freshwater lake on the photochemistry reaction kinetics of ofloxacin and enrofloxacin.
Environmental pollution (Barking, Essex : 1987).
2018 Oct; 241(?):692-700. doi:
10.1016/j.envpol.2018.06.017. [PMID: 29902752] - Liyun Zhao, Hongxin Liu, Luqiong Huo, Miaomiao Wang, Bao Yang, Weimin Zhang, Zhifang Xu, Haibo Tan, Sheng-Xiang Qiu. Structural optimization and antibacterial evaluation of rhodomyrtosone B analogues against MRSA strains.
MedChemComm.
2018 Oct; 9(10):1698-1707. doi:
10.1039/c8md00257f. [PMID: 30429974] - Chikere A Anusiem, Sinyeofori A Brown, Ndidi A Ezejiofor, Ebenezer Barikpoar, Orish E Orisakwe. Isoniazid Pharmacokinetics in the Presence of Ofloxacin and Norfloxacin Antibiotics.
American journal of therapeutics.
2018 Jul; 25(4):e397-e404. doi:
10.1097/mjt.0000000000000032. [PMID: 24451295] - Li Lei, Mujeeb Ur Rehman, Shucheng Huang, Lihong Zhang, Lei Wang, Khalid Mehmood, Hui Zhang, Xiaole Tong, Meng Wang, Jiakui Li. Antimicrobial resistance and prevalence of diarrheagenic Escherichia coli (DEC), in diarrheic yaks of Tibetan Plateau, China.
Acta tropica.
2018 Jun; 182(?):111-114. doi:
10.1016/j.actatropica.2018.02.022. [PMID: 29470944] - Jorge Ignacio González Borroto, Malaika Sharon Awori, Luc Chouinard, Susan Y Smith, Cristina Tarragó, Teresa Blazquez, Domingo Gargallo-Viola, Ilonka Zsolt. Studies on articular and general toxicity of orally administered ozenoxacin in juvenile rats and dogs.
Future microbiology.
2018 05; 13(?):31-40. doi:
10.2217/fmb-2017-0291. [PMID: 29745239] - Tahirah Khaliq, Malik Abdul Waseem, Ali Mohd Lone, Qazi Parvaiz Hassan. Oscimum sanctum extract inhibits growth of Gram positive and Gram negative bacterial strains.
Microbial pathogenesis.
2018 May; 118(?):211-213. doi:
10.1016/j.micpath.2018.03.040. [PMID: 29578064] - Manal Mohamed Elhassan Taha, Hisham Elraih Homeida, Omer Mohammed Elhassan Dafalla, Siddig Ibrahim Abdelwahab. Multidrug resistance, prevalence and phylogenetic analysis of genes encoding class II and III integrons in clinically isolated Escherichia coli.
Cellular and molecular biology (Noisy-le-Grand, France).
2018 Apr; 64(5):122-126. doi:
10.14715/cmb/2018.64.5.21. [PMID: 29729705] - Yan-Rong Ma, Yan Zhou, Jing Huang, Hong-Yan Qin, Pei Wang, Xin-An Wu. The urinary excretion of metformin, ceftizoxime and ofloxacin in high serum creatinine rats: Can creatinine predict renal tubular elimination?.
Life sciences.
2018 Mar; 196(?):110-117. doi:
10.1016/j.lfs.2018.01.017. [PMID: 29355545] - Neng Jiang, Qichun Huang, Jing Liu, Ningsheng Liang, Qing Li, Qinghua Li, Sai-Sai Xie. Design, synthesis and biological evaluation of new coumarin-dithiocarbamate hybrids as multifunctional agents for the treatment of Alzheimer's disease.
European journal of medicinal chemistry.
2018 Feb; 146(?):287-298. doi:
10.1016/j.ejmech.2018.01.055. [PMID: 29407958] - Roya Mirzajani, Nahid Pourreza, Jafar Burromandpiroze. Fabrication of magnetic Fe3O4@nSiO2@mSiO2-NH2 core-shell mesoporous nanocomposite and its application for highly efficient ultrasound assisted dispersive µSPE-spectrofluorimetric detection of ofloxacin in urine and plasma samples.
Ultrasonics sonochemistry.
2018 Jan; 40(Pt A):101-112. doi:
10.1016/j.ultsonch.2017.06.027. [PMID: 28946397] - Elina Karhu, Janne Isojärvi, Pia Vuorela, Leena Hanski, Adyary Fallarero. Identification of Privileged Antichlamydial Natural Products by a Ligand-Based Strategy.
Journal of natural products.
2017 10; 80(10):2602-2608. doi:
10.1021/acs.jnatprod.6b01052. [PMID: 29043803] - Jin-Shuai Lan, Yue Ding, Yun Liu, Ping Kang, Jian-Wei Hou, Xin-Yu Zhang, Sai-Sai Xie, Tong Zhang. Design, synthesis and biological evaluation of novel coumarin-N-benzyl pyridinium hybrids as multi-target agents for the treatment of Alzheimer's disease.
European journal of medicinal chemistry.
2017 Oct; 139(?):48-59. doi:
10.1016/j.ejmech.2017.07.055. [PMID: 28797883] - Muhammad Atif, Arslan Bashir, Nafees Ahmad, Razia Kaneez Fatima, Sehar Saba, Shane Scahill. Predictors of unsuccessful interim treatment outcomes of multidrug resistant tuberculosis patients.
BMC infectious diseases.
2017 09; 17(1):655. doi:
10.1186/s12879-017-2746-5. [PMID: 28962599] - Yunsu Ma, Qianru Wang, Hongwen Zhang, Lijun Xie, Juan Chen, Mao Huang, Yun Liu, Yuanyuan Wang, Libin Wang, Luning Sun, Ning Ou. Simultaneous quantification of antofloxacin and its major metabolite in human urine by HPLC-MS/MS, and its application to a pharmacokinetic study.
Biomedical chromatography : BMC.
2017 Sep; 31(9):. doi:
10.1002/bmc.3962. [PMID: 28205258] - Jin-Shuai Lan, Tong Zhang, Yun Liu, Jing Yang, Sai-Sai Xie, Jing Liu, Ze-Yang Miao, Yue Ding. Design, synthesis and biological activity of novel donepezil derivatives bearing N-benzyl pyridinium moiety as potent and dual binding site acetylcholinesterase inhibitors.
European journal of medicinal chemistry.
2017 Jun; 133(?):184-196. doi:
10.1016/j.ejmech.2017.02.045. [PMID: 28388521] - Aida Lahmar, Ahmed Bedoui, Imen Mokdad-Bzeouich, Zaineb Dhaouifi, Zahar Kalboussi, Imed Cheraif, Kamel Ghedira, Leila Chekir-Ghedira. Reversal of resistance in bacteria underlies synergistic effect of essential oils with conventional antibiotics.
Microbial pathogenesis.
2017 May; 106(?):50-59. doi:
10.1016/j.micpath.2016.10.018. [PMID: 27815129] - Yu-Feng Zhou, Meng-Ting Tao, Wei Huo, Xiao-Ping Liao, Jian Sun, Ya-Hong Liu. In Vivo Pharmacokinetic and Pharmacodynamic Profiles of Antofloxacin against Klebsiella pneumoniae in a Neutropenic Murine Lung Infection Model.
Antimicrobial agents and chemotherapy.
2017 05; 61(5):. doi:
10.1128/aac.02691-16. [PMID: 28264844] - N Hashimoto, K Togami, K Endou, H Onodera, H Tanimoto, S Itagaki, S Chono. Storage stability of serum formulations containing ofloxacin for autologous serum eardrop therapy.
Die Pharmazie.
2017 Mar; 72(3):139-142. doi:
10.1691/ph.2017.6832. [PMID: 29442048] - Aashima Hooda, M Sradhanjali, Popsy. Formulation and Evaluation of Novel Solid Lipid Microparticles for the Sustained Release of Ofloxacin.
Pharmaceutical nanotechnology.
2017; 5(4):329-341. doi:
10.2174/2211738506666171226121720. [PMID: 29278216] - Lydia Kwast, Daniëlle Fiechter, Laura Kruijssen, Rob Bleumink, Irene Ludwig, Marianne Bol-Schoenmakers, Joost Smit, Raymond Pieters. Oral exposure to immunostimulating drugs results in early changes in innate immune parameters in the spleen.
Journal of immunotoxicology.
2016 07; 13(4):535-47. doi:
10.3109/1547691x.2016.1139643. [PMID: 27043250] - Camilla Montesano, Roberta Curini, Manuel Sergi, Dario Compagnone, Gianluca Celani, Vincenzo Varasano, Lucio Petrizzi, Michele Amorena. Determination of marbofloxacin in plasma and synovial fluid by ultrafiltration followed by HPLC-MS/MS.
Journal of pharmaceutical and biomedical analysis.
2016 May; 123(?):31-6. doi:
10.1016/j.jpba.2016.01.061. [PMID: 26859613] - Alexandre Malmartel, Christian Ghasarossian. Bacterial resistance in urinary tract infections in patients with diabetes matched with patients without diabetes.
Journal of diabetes and its complications.
2016 May; 30(4):705-9. doi:
10.1016/j.jdiacomp.2016.01.005. [PMID: 26851821] - Chungang Zhang, Jingya Tang, Dechun Liu, Xuetao Li, Lan Cheng, Xing Tang. Design and evaluation of an innovative floating and bioadhesive multiparticulate drug delivery system based on hollow structure.
International journal of pharmaceutics.
2016 Apr; 503(1-2):41-55. doi:
10.1016/j.ijpharm.2016.02.045. [PMID: 26943975] - Xiao-hu Dai, Yong-gang Xue, Hua-jie Liu, Ling-ling Dai, Han Yan, Ning Li. [Development of Determination Method of Fluoroquinolone Antibiotics in Sludge Based on Solid Phase Extraction and HPLC-Fluorescence Detection Analysis].
Huan jing ke xue= Huanjing kexue.
2016 Apr; 37(4):1553-61. doi:
". [PMID: 27548982] - Fahim Ullah Khan, Fazli Nasir, Zafar Iqbal, Ismail Khan, Naila Shahbaz, Muhammad Hassan, Farhad Ullah. Simultaneous determination of moxifloxacin and ofloxacin in physiological fluids using high performance liquid chromatography with ultraviolet detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2016 Apr; 1017-1018(?):120-128. doi:
10.1016/j.jchromb.2016.03.002. [PMID: 26970846] - Jing Nie, Yang-Guang Wang, Xiao-Feng Gao, Xiao-Kun OuYang, Li-Ye Yang, Di Yu, Wei-Jian Wu, Hong-Ping Xu. Pharmacokinetic study of ofloxacin enantiomers in Pagrosomus major by chiral HPLC.
Biomedical chromatography : BMC.
2016 Mar; 30(3):426-31. doi:
10.1002/bmc.3565. [PMID: 26179954] - Mitra Amoli-Diva, Kamyar Pourghazi, Somayeh Hajjaran. Dispersive micro-solid phase extraction using magnetic nanoparticle modified multi-walled carbon nanotubes coupled with surfactant-enhanced spectrofluorimetry for sensitive determination of lomefloxacin and ofloxacin from biological samples.
Materials science & engineering. C, Materials for biological applications.
2016 Mar; 60(?):30-36. doi:
10.1016/j.msec.2015.11.013. [PMID: 26706503] - Christina Vakh, Aleksei Pochivalov, Vasil Andruch, Leonid Moskvin, Andrey Bulatov. A fully automated effervescence-assisted switchable solvent-based liquid phase microextraction procedure: Liquid chromatographic determination of ofloxacin in human urine samples.
Analytica chimica acta.
2016 Feb; 907(?):54-9. doi:
10.1016/j.aca.2015.12.004. [PMID: 26803002] - Qing Yan, Guozhong Feng, Xu Gao, Chengxiao Sun, Jin-song Guo, Zhiwei Zhu. Removal of pharmaceutically active compounds (PhACs) and toxicological response of Cyperus alternifolius exposed to PhACs in microcosm constructed wetlands.
Journal of hazardous materials.
2016 Jan; 301(?):566-75. doi:
10.1016/j.jhazmat.2015.08.057. [PMID: 26465971] - Elisabeth Poehler, Christin Herzog, Carsten Lotter, Simon A Pfeiffer, Daniel Aigner, Torsten Mayr, Stefan Nagl. Label-free microfluidic free-flow isoelectric focusing, pH gradient sensing and near real-time isoelectric point determination of biomolecules and blood plasma fractions.
The Analyst.
2015 Nov; 140(22):7496-502. doi:
10.1039/c5an01345c. [PMID: 26501586] - Robert Skov, Erika Matuschek, Maria Sjölund-Karlsson, Jenny Åhman, Andreas Petersen, Marc Stegger, Mia Torpdahl, Gunnar Kahlmeter. Development of a Pefloxacin Disk Diffusion Method for Detection of Fluoroquinolone-Resistant Salmonella enterica.
Journal of clinical microbiology.
2015 Nov; 53(11):3411-7. doi:
10.1128/jcm.01287-15. [PMID: 26292292] - Marina Denadai, Quezia Bezerra Cass. Simultaneous determination of fluoroquinolones in environmental water by liquid chromatography-tandem mass spectrometry with direct injection: A green approach.
Journal of chromatography. A.
2015 Oct; 1418(?):177-184. doi:
10.1016/j.chroma.2015.09.066. [PMID: 26427326] - Anthony J Garcia-Prats, Heather R Draper, Stephanie Thee, Kelly E Dooley, Helen M McIlleron, James A Seddon, Lubbe Wiesner, Sandra Castel, H Simon Schaaf, Anneke C Hesseling. Pharmacokinetics and Safety of Ofloxacin in Children with Drug-Resistant Tuberculosis.
Antimicrobial agents and chemotherapy.
2015 Oct; 59(10):6073-9. doi:
10.1128/aac.01404-15. [PMID: 26195507] - Peter John, Waqar Azeem, Muhammad Ashfaq, Islam Ullah Khan, Syed Naeem Razzaq. Stability indicating RP-HPLC method for simultaneous determination of piroxicam and ofloxacin in binary combination.
Pakistan journal of pharmaceutical sciences.
2015 Sep; 28(5):1713-21. doi:
NULL. [PMID: 26408892] - Ahmad Manbohi, Seyyed Hamid Ahmadi. In-tube magnetic solid phase microextraction of some fluoroquinolones based on the use of sodium dodecyl sulfate coated Fe3O4 nanoparticles packed tube.
Analytica chimica acta.
2015 Jul; 885(?):114-21. doi:
10.1016/j.aca.2015.05.030. [PMID: 26231896] - Jose B Carbajo, Alice L Petre, Roberto Rosal, Sonia Herrera, Pedro Letón, Eloy García-Calvo, Amadeo R Fernández-Alba, Jose A Perdigón-Melón. Continuous ozonation treatment of ofloxacin: transformation products, water matrix effect and aquatic toxicity.
Journal of hazardous materials.
2015 Jul; 292(?):34-43. doi:
10.1016/j.jhazmat.2015.02.075. [PMID: 25796038] - Maryam Vosough, Masoumeh Rashvand, Hadi M Esfahani, Kazem Kargosha, Amir Salemi. Direct analysis of six antibiotics in wastewater samples using rapid high-performance liquid chromatography coupled with diode array detector: a chemometric study towards green analytical chemistry.
Talanta.
2015 Apr; 135(?):7-17. doi:
10.1016/j.talanta.2014.12.036. [PMID: 25640119] - Katrijn De Brucker, Yulong Tan, Katlijn Vints, Kaat De Cremer, Annabel Braem, Natalie Verstraeten, Jan Michiels, Jef Vleugels, Bruno P A Cammue, Karin Thevissen. Fungal β-1,3-glucan increases ofloxacin tolerance of Escherichia coli in a polymicrobial E. coli/Candida albicans biofilm.
Antimicrobial agents and chemotherapy.
2015; 59(6):3052-8. doi:
10.1128/aac.04650-14. [PMID: 25753645] - Ndidi A Ezejiofor, Sinyeofori Brown, Ebenezer Barikpoar, Orish E Orisakwe. Effect of ofloxacin and norfloxacin on rifampicin pharmacokinetics in man.
American journal of therapeutics.
2015 Jan; 22(1):29-36. doi:
10.1097/mjt.0b013e31826fc1ba. [PMID: 23817346] - Neslihan Üstündağ-Okur, Evren Homan Gökçe, Duygu İnci Bozbıyık, Sait Eğrilmez, Gökhan Ertan, Özgen Özer. Novel nanostructured lipid carrier-based inserts for controlled ocular drug delivery: evaluation of corneal bioavailability and treatment efficacy in bacterial keratitis.
Expert opinion on drug delivery.
2015; 12(11):1791-807. doi:
10.1517/17425247.2015.1059419. [PMID: 26159181] - Isoken Henrietta Igbinosa. Prevalence and detection of antibiotic-resistant determinant in Salmonella isolated from food-producing animals.
Tropical animal health and production.
2015 Jan; 47(1):37-43. doi:
10.1007/s11250-014-0680-8. [PMID: 25348646] - Dean G Brown, Tricia L May-Dracka, Moriah M Gagnon, Ruben Tommasi. Trends and exceptions of physical properties on antibacterial activity for Gram-positive and Gram-negative pathogens.
Journal of medicinal chemistry.
2014 Dec; 57(23):10144-61. doi:
10.1021/jm501552x. [PMID: 25402200] - Neslihan Ustündağ-Okur, Evren Homan Gökçe, Duygu İnci Bozbıyık, Sait Eğrilmez, Ozgen Ozer, Gökhan Ertan. Preparation and in vitro-in vivo evaluation of ofloxacin loaded ophthalmic nano structured lipid carriers modified with chitosan oligosaccharide lactate for the treatment of bacterial keratitis.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2014 Oct; 63(?):204-15. doi:
10.1016/j.ejps.2014.07.013. [PMID: 25111119] - Gracia Márquez, Eva M Rodríguez, Fernando J Beltrán, Pedro M Álvarez. Solar photocatalytic ozonation of a mixture of pharmaceutical compounds in water.
Chemosphere.
2014 Oct; 113(?):71-8. doi:
10.1016/j.chemosphere.2014.03.093. [PMID: 25065792] - Takashi Koyanagi, Yoshiyuki Yamaura, Koji Yano, Soonih Kim, Hiroshi Yamazaki. Age-related pharmacokinetic changes of acetaminophen, antipyrine, diazepam, diphenhydramine, and ofloxacin in male cynomolgus monkeys and beagle dogs.
Xenobiotica; the fate of foreign compounds in biological systems.
2014 Oct; 44(10):893-901. doi:
10.3109/00498254.2014.903532. [PMID: 24650193] - Milena Marsoni, Fabrizio De Mattia, Massimo Labra, Antonia Bruno, Marcella Bracale, Candida Vannini. Uptake and effects of a mixture of widely used therapeutic drugs in Eruca sativa L. and Zea mays L. plants.
Ecotoxicology and environmental safety.
2014 10; 108(?):52-7. doi:
10.1016/j.ecoenv.2014.05.029. [PMID: 25042244] - Khan Behlol Ayaz Ahmed, Swetha Subramanian, Aravind Sivasubramanian, Ganapathy Veerappan, Anbazhagan Veerappan. Preparation of gold nanoparticles using Salicornia brachiata plant extract and evaluation of catalytic and antibacterial activity.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2014 Sep; 130(?):54-8. doi:
10.1016/j.saa.2014.03.070. [PMID: 24762573] - Hongmin Wang, Ruonan Ning, Yu Shen, Zhenhua Chen, Jinlong Li, Rujun Zhang, Ying Leng, Weimin Zhao. Lithocarpic Acids A-N, 3,4-seco-Cycloartane Derivatives from the Cupules of Lithocarpus polystachyus.
Journal of natural products.
2014 Aug; 77(8):1910-20. doi:
10.1021/np500379f. [PMID: 25098388] - Predrag Djurdjevic, Ivan Jakovljevic, Ljubinka Joksovic, Nevena Ivanovic, Milena Jelikic-Stankov. The effect of some fluoroquinolone family members on biospeciation of copper(II), nickel(II) and zinc(II) ions in human plasma.
Molecules (Basel, Switzerland).
2014 Aug; 19(8):12194-223. doi:
10.3390/molecules190812194. [PMID: 25123186] - Elin Näsström, Nga Tran Vu Thieu, Sabina Dongol, Abhilasha Karkey, Phat Voong Vinh, Tuyen Ha Thanh, Anders Johansson, Amit Arjyal, Guy Thwaites, Christiane Dolecek, Buddha Basnyat, Stephen Baker, Henrik Antti. Salmonella Typhi and Salmonella Paratyphi A elaborate distinct systemic metabolite signatures during enteric fever.
eLife.
2014 Jun; 3(?):. doi:
10.7554/elife.03100. [PMID: 24902583] - Laure Pasquini, Jean-François Munoz, Marie-Noëlle Pons, Jacques Yvon, Xavier Dauchy, Xavier France, Nang Dinh Le, Christian France-Lanord, Tatiana Görner. Occurrence of eight household micropollutants in urban wastewater and their fate in a wastewater treatment plant. Statistical evaluation.
The Science of the total environment.
2014 May; 481(?):459-68. doi:
10.1016/j.scitotenv.2014.02.075. [PMID: 24631609]
