N-NITROSODIPHENYLAMINE (BioDeep_00000002473)

   

human metabolite blood metabolite Volatile Flavor Compounds


代谢物信息卡片


N-Nitrosodiphenylamine, 14C-labeled

化学式: C12H10N2O (198.079309)
中文名称: N-亚硝基二苯胺
谱图信息: 最多检出来源 Homo sapiens(blood) 66.67%

分子结构信息

SMILES: C1=CC=C(C=C1)N(C2=CC=CC=C2)N=O
InChI: InChI=1S/C12H10N2O/c15-13-14(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H

描述信息

CONFIDENCE standard compound; EAWAG_UCHEM_ID 3355
D009676 - Noxae > D002273 - Carcinogens

同义名列表

8 个代谢物同义名

N-Nitrosodiphenylamine, 14C-labeled; N-nitroso-N-phenylaniline; N-NITROSO-DIPHENYLAMINE; N-NITROSODIPHENYLAMINE; nitrosodiphenylamine; Diphenylnitrosamine; N-Nitrosodiphenylamine; N-Nitrosodiphenylamine



数据库引用编号

17 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Chao Zhao, Qiang Lu, Yun Gu, Enchun Pan, Zhongming Sun, Hu Zhang, Jingjing Zhou, Ying Du, Ying Zhang, Yuanmei Feng, Ran Liu, Yuepu Pu, Lihong Yin. Distribution of N-nitrosamines in drinking water and human urinary excretions in high incidence area of esophageal cancer in Huai'an, China. Chemosphere. 2019 Nov; 235(?):288-296. doi: 10.1016/j.chemosphere.2019.06.124. [PMID: 31260869]
  • Youngmin Hong, Kyung Hwan Kim, Byoung-In Sang, Hyunook Kim. Simple quantification method for N-nitrosamines in atmospheric particulates based on facile pretreatment and GC-MS/MS. Environmental pollution (Barking, Essex : 1987). 2017 Jul; 226(?):324-334. doi: 10.1016/j.envpol.2017.04.017. [PMID: 28412030]
  • Minju Lee, Yunho Lee, Fabian Soltermann, Urs von Gunten. Analysis of N-nitrosamines and other nitro(so) compounds in water by high-performance liquid chromatography with post-column UV photolysis/Griess reaction. Water research. 2013 Sep; 47(14):4893-903. doi: 10.1016/j.watres.2013.05.031. [PMID: 23891540]
  • Yuan-Yuan Zhao, Jessica Boyd, Steve E Hrudey, Xing-Fang Li. Characterization of new nitrosamines in drinking water using liquid chromatography tandem mass spectrometry. Environmental science & technology. 2006 Dec; 40(24):7636-41. doi: 10.1021/es061332s. [PMID: 17256506]
  • Masayoshi Sawamura, Yingxia Wu, Chikako Fujiwara, Masato Urushibata. Inhibitory effect of yuzu essential oil on the formation of N-nitrosodimethylamine in vegetables. Journal of agricultural and food chemistry. 2005 May; 53(10):4281-7. doi: 10.1021/jf047816u. [PMID: 15884872]
  • A el-Yazigi, A Yusuf. Expedient liquid chromatographic assay for paclitaxel in plasma after its administration to cancer patients. Therapeutic drug monitoring. 1995 Oct; 17(5):511-5. doi: 10.1097/00007691-199510000-00012. [PMID: 8585115]
  • K E Appel, M Schoepke, T Scheper, S Görsdorf, M Bauszus, C S Rühl, R Kramer, H H Ruf, B Spiegelhalder, M Wiessler. Some aspects of cytochrome P450-dependent denitrosation of N-nitrosamines. IARC scientific publications. 1987; ?(84):117-23. doi: . [PMID: 3679347]
  • K E Appel, C S Rühl, B Spiegelhalder, A G Hildebrandt. Denitrosation of diphenylnitrosamine in vivo. Toxicology letters. 1984 Dec; 23(3):353-8. doi: 10.1016/0378-4274(84)90033-x. [PMID: 6523527]
  • K E Appel, C S Rühl, A G Hildebrandt. Metabolic inactivation of N-nitrosamines by cytochrome P-450 in vitro and in vivo. IARC scientific publications. 1984; ?(57):443-51. doi: . [PMID: 6533036]
  • K Tatsumi, H Yamada, S Kitamura. Reductive metabolism of N-nitrosodiphenylamine to the corresponding hydrazine derivative. Archives of biochemistry and biophysics. 1983 Oct; 226(1):174-81. doi: 10.1016/0003-9861(83)90282-5. [PMID: 6639050]
  • H Ohshima, J C Bereziat, H Bartsch. Measurement of endogenous n-nitrosation in rats and humans by monitoring urinary and faecal excretion of N-nitrosamino acids. IARC scientific publications. 1982; ?(41):397-411. doi: . [PMID: 7141546]