Imazapyr (BioDeep_00000002404)
Secondary id: BioDeep_00000410894
human metabolite blood metabolite
代谢物信息卡片
2-[5-methyl-4-oxo-5-(propan-2-yl)-4,5-dihydro-1H-imidazol-2-yl]pyridine-3-carboxylic acid
化学式: C13H15N3O3 (261.111336)
中文名称: 灭草烟
谱图信息:
最多检出来源 Homo sapiens(blood) 28.52%
分子结构信息
SMILES: CC(C)C1(C(=O)NC(=N1)C2=C(C=CC=N2)C(=O)O)C
InChI: InChI=1S/C13H15N3O3/c1-7(2)13(3)12(19)15-10(16-13)9-8(11(17)18)5-4-6-14-9/h4-7H,1-3H3,(H,17,18)(H,15,16,19)
描述信息
CONFIDENCE standard compound; INTERNAL_ID 2630
D010575 - Pesticides > D006540 - Herbicides
D016573 - Agrochemicals
同义名列表
21 个代谢物同义名
2-[5-methyl-4-oxo-5-(propan-2-yl)-4,5-dihydro-1H-imidazol-2-yl]pyridine-3-carboxylic acid; 2-(4-isopropyl-4-methyl-5-oxo-3H-imidazol-2-yl)pyridine-3-carboxylic acid; 2-(4-Isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl)nicotinic acid; Imazapyr, copper (2) salt; Imazapyr, magnesium salt; Imazapyr, potassium salt; Imazapyr, ammonium salt; Imazapyr, iron (3) salt; Imazapyr, iron (2) salt; Imazapyr, lithium salt; Imazapyr, calcium salt; Imazapyr, sodium salt; Imazapyr, (+-)-isomer; Imazapyr, barium salt; Imazapyr, (S)-isomer; Imazapyr, (+)-isomer; Imazapyr, (-)-isomer; Imazapyr, (R)-isomer; Imazapyr; Arsenal; Imazapyr
数据库引用编号
18 个数据库交叉引用编号
- ChEBI: CHEBI:133187
- ChEBI: CHEBI:82021
- KEGG: C18864
- PubChem: 54738
- HMDB: HMDB0253405
- Metlin: METLIN72626
- ChEMBL: CHEMBL1621900
- Wikipedia: Imazapyr
- CAS: 81334-34-1
- CAS: 94795-74-1
- MoNA: AU263001
- MoNA: AU263003
- MoNA: AU263006
- MoNA: AU263005
- MoNA: AU263002
- PMhub: MS000002532
- PubChem: 124489536
- KNApSAcK: 82021
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Thais Stradioto Melo, Caroline Hernke Thiel, Laryssa Barbosa Xavier da Silva, Sidnei Deuner, André Andres, Gabriele Espinel Ávila, Stefânia Nunes Pires, Germani Concenço. Cumulative potential and half-life of [imazapic + imazapyr] in lowland soils of Rio Grande Do Sul grown with clearfield® rice.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes.
2022; 57(6):450-457. doi:
10.1080/03601234.2022.2063613. [PMID: 35414314] - Rabiatuladawiyah Ruzmi, Muhammad Saiful Ahmad-Hamdani, Norida Mazlan. Ser-653-Asn substitution in the acetohydroxyacid synthase gene confers resistance in weedy rice to imidazolinone herbicides in Malaysia.
PloS one.
2020; 15(9):e0227397. doi:
10.1371/journal.pone.0227397. [PMID: 32925921] - Yen-Hung Wu, Kuan-Ting Liu, Yueh-Lun Shih, I-Jeng Yeh. Chronological serum concentration of imazapyr in a case of life threatening intoxication.
Clinical toxicology (Philadelphia, Pa.).
2019 09; 57(9):824-825. doi:
10.1080/15563650.2018.1562070. [PMID: 30729827] - Gabriela Breccia, Laura Gianotto, Emiliano Altieri, Mariano Bulos, Graciela Nestares. Effect of Ahasl1-1 and Ahasl1-4 alleles on herbicide resistance and its associated dominance in sunflower.
Pest management science.
2019 Apr; 75(4):935-941. doi:
10.1002/ps.5197. [PMID: 30187639] - Motselisi J Koetle, Dyfed Lloyd Evans, Varnika Singh, Sandy J Snyman, R Stuart Rutherford, M Paula Watt. Agronomic evaluation and molecular characterisation of the acetolactate synthase gene in imazapyr tolerant sugarcane (Saccharum hybrid) genotypes.
Plant cell reports.
2018 Aug; 37(8):1201-1213. doi:
10.1007/s00299-018-2306-5. [PMID: 29868986] - Krystal M Isbister, Eric G Lamb, Katherine J Stewart. Herbicide Toxicity Testing with Non-Target Boreal Plants: The Sensitivity of Achillea millefolium L. and Chamerion angustifolium L. to Triclopyr and Imazapyr.
Environmental management.
2017 07; 60(1):136-156. doi:
10.1007/s00267-017-0867-7. [PMID: 28424880] - Jaqueline Ineu Golombieski, Fernando Jonas Sutili, Joseânia Salbego, Débora Seben, Luciane Tourem Gressler, Jéssyka Arruda da Cunha, Leticia Trevisan Gressler, Renato Zanella, Rodrigo de Almeida Vaucher, Enio Marchesan, Bernardo Baldisserotto. Imazapyr+imazapic herbicide determines acute toxicity in silver catfish Rhamdia quelen.
Ecotoxicology and environmental safety.
2016 Jun; 128(?):91-9. doi:
10.1016/j.ecoenv.2016.02.010. [PMID: 26896896] - Lisa Maria Dersch, Veronique Beckers, Detlev Rasch, Guido Melzer, Christoph Bolten, Katina Kiep, Horst Becker, Oliver Ernst Bläsing, Regine Fuchs, Thomas Ehrhardt, Christoph Wittmann. Novel Approach for High-Throughput Metabolic Screening of Whole Plants by Stable Isotopes.
Plant physiology.
2016 05; 171(1):25-41. doi:
10.1104/pp.15.01217. [PMID: 26966172] - Cameron H Douglass, Scott J Nissen, Andrew R Kniss. Efficacy and environmental fate of imazapyr from directed helicopter applications targeting Tamarix species infestations in Colorado.
Pest management science.
2016 Feb; 72(2):379-87. doi:
10.1002/ps.4016. [PMID: 25827499] - David F Spencer. Evaluation of stem injection for managing giant reed (Arundo donax).
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes.
2014; 49(9):633-8. doi:
10.1080/03601234.2014.922397. [PMID: 25035911] - Robert Fürst, Ilse Zündorf. Plant-derived anti-inflammatory compounds: hopes and disappointments regarding the translation of preclinical knowledge into clinical progress.
Mediators of inflammation.
2014; 2014(?):146832. doi:
10.1155/2014/146832. [PMID: 24987194] - Rosinei Aparecida Souza, Letícia Carlos Babujia, Adriana Pereira Silva, Maria de Fátima Guimarães, Carlos Arrabal Arias, Mariangela Hungria. Impact of the ahas transgene and of herbicides associated with the soybean crop on soil microbial communities.
Transgenic research.
2013 Oct; 22(5):877-92. doi:
10.1007/s11248-013-9691-x. [PMID: 23420042] - Gabriela Breccia, Tatiana Vega, Silvina A Felitti, Liliana Picardi, Graciela Nestares. Differential expression of acetohydroxyacid synthase genes in sunflower plantlets and its response to imazapyr herbicide.
Plant science : an international journal of experimental plant biology.
2013 Jul; 208(?):28-33. doi:
10.1016/j.plantsci.2013.03.008. [PMID: 23683926] - C T Citadin, A R R Cruz, F J L Aragão. Development of transgenic imazapyr-tolerant cowpea (Vigna unguiculata).
Plant cell reports.
2013 Apr; 32(4):537-43. doi:
10.1007/s00299-013-1385-6. [PMID: 23306633] - Jaimie Schnell, Hélène Labbé, Nik Kovinich, Yuzuki Manabe, Brian Miki. Comparability of imazapyr-resistant Arabidopsis created by transgenesis and mutagenesis.
Transgenic research.
2012 Dec; 21(6):1255-64. doi:
10.1007/s11248-012-9597-z. [PMID: 22430369] - T Vega, G Breccia, M Gil, R Zorzoli, L Picardi, G Nestares. Acetohydroxyacid synthase (AHAS) in vivo assay for screening imidazolinone-resistance in sunflower (Helianthus annuus L.).
Plant physiology and biochemistry : PPB.
2012 Dec; 61(?):103-7. doi:
10.1016/j.plaphy.2012.09.013. [PMID: 23123550] - Heping Han, Qin Yu, Edison Purba, Mei Li, Michael Walsh, Shane Friesen, Stephen B Powles. A novel amino acid substitution Ala-122-Tyr in ALS confers high-level and broad resistance across ALS-inhibiting herbicides.
Pest management science.
2012 Aug; 68(8):1164-70. doi:
10.1002/ps.3278. [PMID: 22431132] - John D Stark, Xue Dong Chen, Catherine S Johnson. Effects of herbicides on Behr's metalmark butterfly, a surrogate species for the endangered butterfly, Lange's metalmark.
Environmental pollution (Barking, Essex : 1987).
2012 May; 164(?):24-7. doi:
10.1016/j.envpol.2012.01.011. [PMID: 22310058] - Carlos A Sala, Mariano Bulos, Emiliano Altieri, Brigitte Weston. Response to imazapyr and dominance relationships of two imidazolinone-tolerant alleles at the Ahasl1 locus of sunflower.
TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik.
2012 Feb; 124(2):385-96. doi:
10.1007/s00122-011-1713-6. [PMID: 21964993] - G R Vianna, F J L Aragão, E L Rech. A minimal DNA cassette as a vector for genetic transformation of soybean (Glycine max).
Genetics and molecular research : GMR.
2011 Mar; 10(1):382-90. doi:
10.4238/vol10-1gmr1058. [PMID: 21365554] - Qin Yu, Heping Han, Martin M Vila-Aiub, Stephen B Powles. AHAS herbicide resistance endowing mutations: effect on AHAS functionality and plant growth.
Journal of experimental botany.
2010 Sep; 61(14):3925-34. doi:
10.1093/jxb/erq205. [PMID: 20627897] - Malay Das, Jay R Reichman, Georg Haberer, Gerhard Welzl, Felipe F Aceituno, Michael T Mader, Lidia S Watrud, Thomas G Pfleeger, Rodrigo A Gutiérrez, Anton R Schäffner, David M Olszyk. A composite transcriptional signature differentiates responses towards closely related herbicides in Arabidopsis thaliana and Brassica napus.
Plant molecular biology.
2010 Mar; 72(4-5):545-56. doi:
10.1007/s11103-009-9590-y. [PMID: 20043233] - David Olszyk, Thomas Pfleeger, E Henry Lee, Milton Plocher. Potato (Solanum tuberosum) greenhouse tuber production as an assay for asexual reproduction effects from herbicides.
Environmental toxicology and chemistry.
2010 Jan; 29(1):111-21. doi:
10.1002/etc.12. [PMID: 20821425] - Christy W Rose, Reginald J Millwood, Hong S Moon, Murali R Rao, Matthew D Halfhill, Paul L Raymer, Suzanne I Warwick, Hani Al-Ahmad, Jonathan Gressel, C Neal Stewart. Genetic load and transgenic mitigating genes in transgenic Brassica rapa (field mustard) x Brassica napus (oilseed rape) hybrid populations.
BMC biotechnology.
2009 Oct; 9(?):93. doi:
10.1186/1472-6750-9-93. [PMID: 19878583] - Jonathan Gressel. Crops with target-site herbicide resistance for Orobanche and Striga control.
Pest management science.
2009 May; 65(5):560-5. doi:
10.1002/ps.1738. [PMID: 19280593] - Maria Anete S Valente, Jerusa A Q A Faria, Juliana R L Soares-Ramos, Pedro A B Reis, Guilherme L Pinheiro, Newton D Piovesan, Angélica T Morais, Carlos C Menezes, Marco A O Cano, Luciano G Fietto, Marcelo E Loureiro, Francisco J L Aragão, Elizabeth P B Fontes. The ER luminal binding protein (BiP) mediates an increase in drought tolerance in soybean and delays drought-induced leaf senescence in soybean and tobacco.
Journal of experimental botany.
2009; 60(2):533-46. doi:
10.1093/jxb/ern296. [PMID: 19052255] - Qin Yu, Heping Han, Stephen B Powles. Mutations of the ALS gene endowing resistance to ALS-inhibiting herbicides in Lolium rigidum populations.
Pest management science.
2008 Dec; 64(12):1229-36. doi:
10.1002/ps.1624. [PMID: 18636424] - Carlos A Sala, Mariano Bulos, Mariel Echarte, Sherry R Whitt, Robert Ascenzi. Molecular and biochemical characterization of an induced mutation conferring imidazolinone resistance in sunflower.
TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik.
2008 Dec; 118(1):105-12. doi:
10.1007/s00122-008-0880-6. [PMID: 18784913] - Thomas Pfleeger, David Olszyk, Milton Plocher, Solomon Yilma. Effects of low concentrations of herbicides on full-season, field-grown potatoes.
Journal of environmental quality.
2008 Nov; 37(6):2070-82. doi:
10.2134/jeq2007.0376. [PMID: 18948460] - Nayche L Ivo, Cristina P Nascimento, Lívia S Vieira, Francisco A P Campos, Francisco J L Aragão. Biolistic-mediated genetic transformation of cowpea (Vigna unguiculata) and stable Mendelian inheritance of transgenes.
Plant cell reports.
2008 Sep; 27(9):1475-83. doi:
10.1007/s00299-008-0573-2. [PMID: 18587583] - Edson José Fragiorge, Alexandre Azenha Alves de Rezende, Ulrich Graf, Mário Antônio Spanó. Comparative genotoxicity evaluation of imidazolinone herbicides in somatic cells of Drosophila melanogaster.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2008 Jan; 46(1):393-401. doi:
10.1016/j.fct.2007.08.022. [PMID: 17910989] - Yuzuki Manabe, Nicholas Tinker, Adam Colville, Brian Miki. CSR1, the sole target of imidazolinone herbicide in Arabidopsis thaliana.
Plant & cell physiology.
2007 Sep; 48(9):1340-58. doi:
10.1093/pcp/pcm105. [PMID: 17693453] - Masaki Endo, Keishi Osakabe, Hiroaki Ichikawa, Seiichi Toki. Molecular characterization of true and ectopic gene targeting events at the acetolactate synthase gene in Arabidopsis.
Plant & cell physiology.
2006 Mar; 47(3):372-9. doi:
10.1093/pcp/pcj003. [PMID: 16418231] - Hani Al-Ahmad, Shmuel Galili, Jonathan Gressel. Poor competitive fitness of transgenically mitigated tobacco in competition with the wild type in a replacement series.
Planta.
2005 Oct; 222(2):372-85. doi:
10.1007/s00425-005-1540-6. [PMID: 15931502] - Maria Nivea P Dias, Marcus R D B Pereira, Ramiro F López-Ovejero, Pedro J Christoffoleti, Juliano F Barela, Valdemar L Tornisielo. Population dynamics of Digitaria spp submitted to selection pressure by herbicides in sugarcane crop.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes.
2005; 40(1):21-8. doi:
10.1081/pfc-200034200. [PMID: 15656158] - Cesar Koppe Grisolia, Marina Rolim Bilich, Lia Menezes Formigli. A comparative toxicologic and genotoxic study of the herbicide arsenal, its active ingredient imazapyr, and the surfactant nonylphenol ethoxylate.
Ecotoxicology and environmental safety.
2004 Sep; 59(1):123-6. doi:
10.1016/j.ecoenv.2004.01.014. [PMID: 15261733] - Maria D Osuna, Albert J Fischer, Rafael De Prado. Herbicide resistance in Aster squamatus conferred by a less sensitive form of acetolactate synthase.
Pest management science.
2003 Nov; 59(11):1210-6. doi:
10.1002/ps.757. [PMID: 14620047] - Yong In Kuk, Ha Il Jung, Oh Do Kwon, Do Jin Lee, Nilda R Burgos, Ja Ock Guh. Sulfonylurea herbicide-resistant Monochoria vaginalis in Korean rice culture.
Pest management science.
2003 Sep; 59(9):949-61. doi:
10.1002/ps.722. [PMID: 12974347] - Romina P Barbagallo, Kevin Oxborough, Kenneth E Pallett, Neil R Baker. Rapid, noninvasive screening for perturbations of metabolism and plant growth using chlorophyll fluorescence imaging.
Plant physiology.
2003 Jun; 132(2):485-93. doi:
10.1104/pp.102.018093. [PMID: 12805581] - C Casado, M D Osuna, R De Prado. Evaluation of resistance in Amaranthus quitensis Kunth populations to imazethapyr and other imidazolinones.
Communications in agricultural and applied biological sciences.
2003; 68(4 Pt A):323-9. doi:
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Molecular & general genetics : MGG.
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