Trichlorfon (BioDeep_00000002324)
Secondary id: BioDeep_00000404964
human metabolite blood metabolite
代谢物信息卡片
1-Hydroxy-2,2,2-trichloroethylphosphonic acid dimethyl ester
化学式: C4H8Cl3O4P (255.9226)
中文名称: 敌百虫标准溶液, 敌百虫
谱图信息:
最多检出来源 Homo sapiens(blood) 88.97%
分子结构信息
SMILES: COP(=O)(C(C(Cl)(Cl)Cl)O)OC
InChI: InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3
描述信息
P - Antiparasitic products, insecticides and repellents > P02 - Anthelmintics > P02B - Antitrematodals > P02BB - Organophosphorous compounds
D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D002800 - Cholinesterase Inhibitors
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics
C471 - Enzyme Inhibitor > C47792 - Acetylcholinesterase Inhibitor
D010575 - Pesticides > D007306 - Insecticides
D004791 - Enzyme Inhibitors
D016573 - Agrochemicals
同义名列表
23 个代谢物同义名
1-Hydroxy-2,2,2-trichloroethylphosphonic acid dimethyl ester; 1-Hydroxy-2,2,2-trichloroethylphosphonate dimethyl ester; dimethyl (2,2,2-trichloro-1-hydroxyethyl)phosphonate; Methyl chlorophos; (+-)-Trichlorfon; Metrifonic acid; Metrifonatum; Trichlorphon; Metriphonate; Metrifonato; Metrifonate; TRICHLORFON; Chlorophos; Chlorofos; Bilarcil; Dipterex; Foschlor; Neguvon; Ricifon; briten; Dylox; Metrifonate; Trichlorfon
数据库引用编号
20 个数据库交叉引用编号
- ChEBI: CHEBI:6908
- KEGG: C07971
- KEGGdrug: D00805
- PubChem: 5853
- HMDB: HMDB0254686
- Metlin: METLIN2920
- DrugBank: DB11473
- ChEMBL: CHEMBL167150
- Wikipedia: Metrifonate
- MeSH: Trichlorfon
- CAS: 1081812-64-7
- CAS: 56042-26-3
- CAS: 56042-27-4
- CAS: 26373-97-7
- CAS: 52-68-6
- PMhub: MS000002347
- PubChem: 10172
- NIKKAJI: J2.309D
- RefMet: Trichlorfon
- KNApSAcK: 6908
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Hui-Hui Meng, Wen-Ya Liu, Wen-Long Zhao, Qi Zheng, Jun-Song Wang. Study on the acute toxicity of trichlorfon and its breakdown product dichlorvos to goldfish (Carassius auratus) based on 1H NMR metabonomics.
Environmental science and pollution research international.
2023 Dec; 30(60):125664-125676. doi:
10.1007/s11356-023-31012-7. [PMID: 38001290] - Yang Zhao, Shipo Li, Duncan James Lessing, Weihua Chu. The attenuating effects of synbiotic containing Cetobacterium somerae and Astragalus polysaccharide against trichlorfon-induced hepatotoxicity in crucian carp (Carassius carassius).
Journal of hazardous materials.
2023 Sep; 461(?):132621. doi:
10.1016/j.jhazmat.2023.132621. [PMID: 37748306] - Chao Zhang, Feng He, Lanzhou Chen. Phytoremediation of cadmium-trichlorfon co-contaminated water by Indian mustard (Brassica juncea): growth and physiological responses.
International journal of phytoremediation.
2023 Jul; ?(?):1-10. doi:
10.1080/15226514.2023.2237119. [PMID: 37463105] - Jianlu Zhang, Mingzhen Zhu, Qijun Wang, Hui Yang. The Combined Use of Copper Sulfate and Trichlorfon Exerts Stronger Toxicity on the Liver of Zebrafish.
International journal of molecular sciences.
2023 Jul; 24(13):. doi:
10.3390/ijms241311203. [PMID: 37446380] - Qiqiang Li, Peiying Wang, Caihua Zou, Fei Ge, Feng Li, Yun Liu, Dayi Zhang, Jiang Tian. Dynamics of dominant rhizospheric microbial communities responsible for trichlorfon absorption and translocation in maize seedlings.
Journal of hazardous materials.
2023 Jun; 451(?):131096. doi:
10.1016/j.jhazmat.2023.131096. [PMID: 36893602] - Cassiano Ricardo Schavinski, Maurício Beux Dos Santos, James Eduardo Lago Londero, Marcelo Carvalho da Rocha, Aline Monique Blank do Amaral, Nathalia Quintero Ruiz, Giovana da Silva Leandro, Vania Lucia Loro, André Passaglia Schuch. Effects of isolated and combined exposures of Boana curupi (Anura: Hylidae) tadpoles to environmental doses of trichlorfon and ultraviolet radiation.
Mutation research. Genetic toxicology and environmental mutagenesis.
2022 Nov; 883-884(?):503549. doi:
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Mikrochimica acta.
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Journal of fish diseases.
2022 Jan; 45(1):203-212. doi:
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