Verbascoside (BioDeep_00000230508)

 

Secondary id: BioDeep_00000003701, BioDeep_00000297382, BioDeep_00000862201

natural product PANOMIX_OTCML-2023


代谢物信息卡片


[(2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-tetrahydropyran-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate

化学式: C29H36O15 (624.2054106)
中文名称: 类叶升麻苷, 毛蕊花甙, 麦角甾苷, 毛蕊花糖苷, 毛蕊花糖苷
谱图信息: 最多检出来源 Viridiplantae(plant) 6.01%

分子结构信息

SMILES: CC1C(C(C(C(O1)OC2C(C(OC(C2OC(=O)C=CC3=CC(=C(C=C3)O)O)CO)OCCC4=CC(=C(C=C4)O)O)O)O)O)O
InChI: InChI=1S/C29H36O15/c1-13-22(36)23(37)24(38)29(41-13)44-27-25(39)28(40-9-8-15-3-6-17(32)19(34)11-15)42-20(12-30)26(27)43-21(35)7-4-14-2-5-16(31)18(33)10-14/h2-7,10-11,13,20,22-34,36-39H,8-9,12H2,1H3/b7-4+/t13-,20+,22-,23+,24+,25+,26+,27+,28+,29-/m0/s1

描述信息

Acteoside is a glycoside that is the alpha-L-rhamnosyl-(1->3)-beta-D-glucoside of hydroxytyrosol in which the hydroxy group at position 4 of the glucopyranosyl moiety has undergone esterification by formal condensation with trans-caffeic acid. It has a role as a neuroprotective agent, an antileishmanial agent, an anti-inflammatory agent, a plant metabolite and an antibacterial agent. It is a cinnamate ester, a disaccharide derivative, a member of catechols, a polyphenol and a glycoside. It is functionally related to a hydroxytyrosol and a trans-caffeic acid.
Acteoside is under investigation in clinical trial NCT02662283 (Validity and Security of Reh-acteoside Therapy for Patients of IgA Nephropathy).
Acteoside is a natural product found in Orobanche amethystea, Barleria lupulina, and other organisms with data available.
See also: Harpagophytum zeyheri root (part of).
A glycoside that is the alpha-L-rhamnosyl-(1->3)-beta-D-glucoside of hydroxytyrosol in which the hydroxy group at position 4 of the glucopyranosyl moiety has undergone esterification by formal condensation with trans-caffeic acid.
D007155 - Immunologic Factors > D007166 - Immunosuppressive Agents
D064449 - Sequestering Agents > D002614 - Chelating Agents
D020011 - Protective Agents > D000975 - Antioxidants
D000890 - Anti-Infective Agents
D000970 - Antineoplastic Agents
Verbascoside is isolated from Acanthus mollis, acts as an ATP-competitive inhibitor of PKC, with an IC50 of 25 μM, and has antitumor, anti-inflammatory and antineuropathic pain activity.
Verbascoside is isolated from Acanthus mollis, acts as an ATP-competitive inhibitor of PKC, with an IC50 of 25 μM, and has antitumor, anti-inflammatory and antineuropathic pain activity.

同义名列表

36 个代谢物同义名

[(2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-tetrahydropyran-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate; (2R,3R,4R,5R,6R)-6-(3,4-Dihydroxyphenethoxy)-5-hydroxy-2-(hydroxymethyl)-4-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl (E)-3-(3,4-dihydroxyphenyl)acrylate; ((2R,3R,4R,5R,6R)-6-(3,4-dihydroxyphenethoxy)-5-hydroxy-2-(hydroxymethyl)-4-((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)tetrahydro-2H-pyran-3-yl) 3-(3,4-dihydroxyphenyl)acrylate; ((2R,3R,4R,5R,6R)-6-(3,4-dihydroxyphenethoxy)-5-hydroxy-2-(hydroxymethyl)-4-((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)tetrahydro-2H-pyran-3-yl)3-(3,4-dihydroxyphenyl)acrylate; (2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-3-yl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate; [(2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate; .beta.-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 3-O-(6-deoxy-.alpha.-L-mannopyranosyl)-, 4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate]; .BETA.-D-GLUCOPYRANOSIDE, 2-(3,4-DIHYDROXYPHENYL)ETHYL 3-O-(6-DEOXY-.ALPHA.-L-MANNOPYRANOSYL)-, 4-((2E)-3-(3,4-DIHYDROXYPHENYL)-2-PROPENOATE); .beta.-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl3-O-(6-deoxy-.alpha.-L-mannopyranosyl)-, 4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate]; glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 3-O-(6-deoxy-alpha-L-mannopyranosyl)-, 4-(3-(3,4-dihydroxyphenyl)-2-propenoate), (E)-beta-D-; beta-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 3-O-(6-deoxy-alpha-L-mannopyranosyl)-, 4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate]; 2-(3,4-dihydroxyphenyl)ethyl 3-O-(6-deoxy-alpha-L-mannopyranosyl)-4-O-((2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl)-beta-D-glucopyranoside; 2-(3,4-dihydroxyphenyl)ethyl 3-O-(6-deoxy-alpha-L-mannopyranosyl)-4-O-[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]-beta-D-glucopyranoside; 2-(3,4-dihydroxyphenyl)ethyl 3-O-(alpha-L-rhamnopyranosyl)-4-O-((2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl)-beta-D-glucopyranoside; 2-(3,4-dihydroxyphenyl)ethyl 3-O-(alpha-L-rhamnopyranosyl)-4-O-[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]-beta-D-glucopyranoside; (3,4-Dihydroxyphenyl)ethyl O-.alpha.-rhamnopyranosyl(1->3)-4-O-caffeoyl-.beta.-D glucopyranoside; Verbascoside, United States Pharmacopeia (USP) Reference Standard; Verbascoside, primary pharmaceutical reference standard; Verbascoside, >=99\\% (HPLC); FBSKJMQYURKNSU-ZLSOWSIRSA-N; Acetoside (Verbascoside); Acteoside; Verbascoside; VERBASCOSIDE (USP-RS); VERBASCOSIDE [USP-RS]; VERBASCOSIDE [INCI]; UNII-3TGX09BD5B; STEREOSPERMIN; Reh-acteoside; Verbascoside; Verbacoside; 3TGX09BD5B; RUSSETINOL; kusaginin; acteoside; acetoside; TJC160



数据库引用编号

22 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Qiancheng Mao, Hongxiu Zhang, Zhe Zhang, Yanting Lu, Jin Pan, Dongjing Guo, Liuxuan Huang, Haoquan Tian, Ke Ma. Co-decoction of Lilii bulbus and Radix Rehmannia Recens and its key bioactive ingredient verbascoside inhibit neuroinflammation and intestinal permeability associated with chronic stress-induced depression via the gut microbiota-brain axis. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jul; 129(?):155510. doi: 10.1016/j.phymed.2024.155510. [PMID: 38696921]
  • Zehui Li, Jiashan Li, Yuan Li, Li Guo, Panyu Xu, Hanqian Du, Na Lin, Ying Xu. The role of Cistanches Herba and its ingredients in improving reproductive outcomes: A comprehensive review. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jul; 129(?):155681. doi: 10.1016/j.phymed.2024.155681. [PMID: 38718638]
  • Mayuree Kanlayavattanakul, Mattaka Khongkow, Nattaya Lourith. Wound healing and photoprotection properties of Acanthus ebracteatus Vahl. extracts standardized in verbascoside. Scientific reports. 2024 01; 14(1):1904. doi: 10.1038/s41598-024-52511-8. [PMID: 38253627]
  • Federica Blando, Giovanni Mita, Gian Pietro Di Sansebastiano, Isabella Nicoletti, Enrica Donati. Highly Efficient Verbascoside Production from Olive (Olea europea L. var. Cellina di Nardò) In Vitro Cell Cultures. Journal of agricultural and food chemistry. 2024 Jan; 72(2):1162-1169. doi: 10.1021/acs.jafc.3c06604. [PMID: 38166105]
  • Wenya Gao, Shuangrong Gao, Yan Zhang, Mengxiao Wang, Yuyang Liu, Tao Li, Chang Gao, Yanyan Zhou, Baolin Bian, Hongjie Wang, Xiaolu Wei, Takashi Sato, Nan Si, Wei Zhao, Haiyu Zhao. Altered metabolic profiles and targets relevant to the protective effect of acteoside on diabetic nephropathy in db/db mice based on metabolomics and network pharmacology studies. Journal of ethnopharmacology. 2024 Jan; 318(Pt B):117073. doi: 10.1016/j.jep.2023.117073. [PMID: 37619856]
  • Wei Zhang, Peng Zhang, Le-Hua Xu, Kai Gao, Juan-Li Zhang, Min-Na Yao, Rui-Li Li, Chao Guo, Jing-Wen Wang, Quan-Xiang Wu. Ethanol extract of Verbena officinalis alleviates MCAO-induced ischaemic stroke by inhibiting IL17A pathway-regulated neuroinflammation. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jan; 123(?):155237. doi: 10.1016/j.phymed.2023.155237. [PMID: 38056148]
  • Taghreed A Majrashi, Mahmoud A El Hassab, Sara H Mahmoud, Ahmed Mostafa, Engy A Wahsh, Eslam B Elkaeed, Fatma E Hassan, Wagdy M Eldehna, Shimaa M Abdelgawad. In vitro biological evaluation and in silico insights into the antiviral activity of standardized olive leaves extract against SARS-CoV-2. PloS one. 2024; 19(4):e0301086. doi: 10.1371/journal.pone.0301086. [PMID: 38662719]
  • Cheng-Lu Yu, Fang Lu, Dong-Hua Yu, Xiao-Min Xu, Peng Xu, Shu-Min Liu. [Mechanism of acteoside in prevention and treatment of gouty arthritis based on liver metabolomics]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2024 Jan; 49(1):224-231. doi: 10.19540/j.cnki.cjcmm.20230808.402. [PMID: 38403355]
  • Saeed Ghasemi, Mehdi Evazalipour, Nastaran Peyghanbari, Ehsan Zamani, Peter Bellstedt, Mahan Molaee, Diba Eghbali Koohi, Fatemeh Yousefbeyk. Isolation and structure elucidation of the compounds from Teucrium hyrcanicum L. and the investigation of cytotoxicity, antioxidant activity, and protective effect on hydrogen peroxide-induced oxidative stress. BMC complementary medicine and therapies. 2023 Dec; 23(1):447. doi: 10.1186/s12906-023-04262-8. [PMID: 38087220]
  • Samed Şimşek, Hüseyin Akşit, Ali Aydın, Ekrem Köksal. Ferruginoside D: A Novel Phenylethanoid from Verbascum leiocarpum. Chemistry & biodiversity. 2023 Dec; 20(12):e202301200. doi: 10.1002/cbdv.202301200. [PMID: 37909246]
  • Xiaoya Li, Zhilong Liu, Zhixiu He, Xiaocheng Wang, Rongshan Li, Junwei Wang, Guiqiao Ma, Peipei Zhang, Chanjuan Ma. Acteoside protects podocyte against apoptosis through regulating AKT/GSK-3β signaling pathway in db/db mice. BMC endocrine disorders. 2023 Oct; 23(1):230. doi: 10.1186/s12902-023-01483-3. [PMID: 37872577]
  • Francesca Sciandra, Patrizia Bottoni, Marinella De Leo, Alessandra Braca, Andrea Brancaccio, Manuela Bozzi. Verbascoside Elicits Its Beneficial Effects by Enhancing Mitochondrial Spare Respiratory Capacity and the Nrf2/HO-1 Mediated Antioxidant System in a Murine Skeletal Muscle Cell Line. International journal of molecular sciences. 2023 Oct; 24(20):. doi: 10.3390/ijms242015276. [PMID: 37894956]
  • Guo Ziliang, Qian Qingyuan, L I Xiaolin, Zhu Yuting, Ren Jun, L I Maoxing. Efficacy of verbascoside, echinacoside, crenatoside on altitude-induced fatigue in rats and possible mechanism. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. 2023 10; 43(5):934-943. doi: 10.19852/j.cnki.jtcm.20230630.001. [PMID: 37679981]
  • Jingzi Chen, Jiaming Ge, Weisan Chen, Ying Zhao, Tianbao Song, Kun Fu, Xiankuan Li, Yanchao Zheng. UPLC-Q-TOF-MS based investigation into the bioactive compounds and molecular mechanisms of Lamiophlomis Herba against hepatic fibrosis. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Sep; 121(?):155085. doi: 10.1016/j.phymed.2023.155085. [PMID: 37757709]
  • Kang Wang, Pei Liu, Si-Fan Wang, Jie-Yu Zhang, Zhi-Zhi Hu, Yu-Qi Mei, Ying-Bo Yang, Zheng-Tao Wang, Li Yang. [Quality evaluation of Compound Cheqian Tablets based on UPLC-Q-TOF-MS/MS, network pharmacology and "double external standards" QAMS]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2023 Sep; 48(17):4675-4685. doi: 10.19540/j.cnki.cjcmm.20230605.302. [PMID: 37802806]
  • Yi Zhao, Sijia Wang, Jin Pan, Ke Ma. Verbascoside: A neuroprotective phenylethanoid glycosides with anti-depressive properties. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Aug; 120(?):155027. doi: 10.1016/j.phymed.2023.155027. [PMID: 37657207]
  • Lipeng Wu, Weisu Huang, Kejie Peng, Yixuan Wang, Qi Chen, Baiyi Lu. Enhancing the stability, BBB permeability and neuroprotective activity of verbascoside in vitro using lipid nanocapsules in combination with menthol. Food chemistry. 2023 Jul; 414(?):135682. doi: 10.1016/j.foodchem.2023.135682. [PMID: 36827775]
  • Elizabeth Rubio-Rodríguez, Ileana Vera-Reyes, Aída Araceli Rodríguez-Hernández, Alma Rosa López-Laredo, Ana C Ramos-Valdivia, Gabriela Trejo-Tapia. Mixed elicitation with salicylic acid and hydrogen peroxide modulates the phenolic and iridoid pathways in Castilleja tenuiflora plants. Planta. 2023 Jun; 258(1):20. doi: 10.1007/s00425-023-04177-1. [PMID: 37326881]
  • Yushiro Fuji, Kai Uchida, Tomoyoshi Akashi, Takashi Ohtsuki, Hiroshi Matsufuji, Masami Yokota Hirai. Molecular Identification of UDP-Sugar Dependent Glycosyltransferase and Acyltransferase Involved in the Phenylethanoid Glycoside Biosynthesis Induced by Methyl Jasmonate in Sesamum indicum L. Plant & cell physiology. 2023 May; ?(?):. doi: 10.1093/pcp/pcad053. [PMID: 37233612]
  • Zheng Ran, Bowei Ju, Lin Cao, Qiang Hou, Limei Wen, Ruoyu Geng, Yucheng Liao, Junping Hu, Jianhua Yang. Microbiome-metabolomics analysis reveals the potential effect of verbascoside in alleviating cognitive impairment in db/db mice. Food & function. 2023 Apr; 14(8):3488-3508. doi: 10.1039/d2fo03110h. [PMID: 37000613]
  • Xinliang Wang, Chanjuan Yang, Yi Ru, Liangqi Xie, Baoguo Xiao, Xiaoming Jin, Cungen Ma, Zhi Chai, Huijie Fan. An optimal combination of five main monomer components in Wuzi Yanzong Pill that prevents neural tube defects and reduces apoptosis and oxidative stress. Journal of ethnopharmacology. 2023 Apr; 313(?):116540. doi: 10.1016/j.jep.2023.116540. [PMID: 37088238]
  • Yihan Yang, Daoyi Xi, Yanan Wu, Tao Liu. Complete Biosynthesis of Phenylethanoid Glycoside Verbascoside. Plant communications. 2023 Mar; ?(?):100592. doi: 10.1016/j.xplc.2023.100592. [PMID: 36935606]
  • Tugce Demiroz Akbulut, Fadime Aydin Kose, Betul Demirci, Sura Baykan. Chemical Profile and Cytotoxicity Evaluation of Aerial Parts of Marrubium vulgare L. From Different Locations in Turkey. Chemistry & biodiversity. 2023 Mar; ?(?):e202201188. doi: 10.1002/cbdv.202201188. [PMID: 36929733]
  • Inga Kwiecień, Aleksandra Łukaszyk, Natalizia Miceli, Maria Fernanda Taviano, Federica Davì, Elżbieta Kędzia, Halina Ekiert. In Vitro Cultures of Scutellaria brevibracteata subsp. subvelutina as a Source of Bioactive Phenolic Metabolites. Molecules (Basel, Switzerland). 2023 Feb; 28(4):. doi: 10.3390/molecules28041785. [PMID: 36838774]
  • Wenya Gao, Yanyan Zhou, Chunying Li, Ting Liu, Haiyu Zhao, Mengxiao Wang, Xiaolu Wei, Hongjie Wang, Jian Yang, Nan Si, Aihua Liang, Baolin Bian, Takashi Sato. Studies on the metabolism and mechanism of acteoside in treating chronic glomerulonephritis. Journal of ethnopharmacology. 2023 Feb; 302(Pt A):115866. doi: 10.1016/j.jep.2022.115866. [PMID: 36332760]
  • Camila Carla Guimarães, Camila Mira Sandy, Rebeca Figueira, Mirani da Rocha Gonçalves, Eduardo José Crevelin, Pedro Henrique Cardoso, Alexandre Todorovic Fabro, Fabio Carmona, Marcos de Carvalho Borges, Ana Maria Soares Pereira. Anti-asthmatic activity of standardized hydro-ethanolic and aqueous extracts of Stachytarpheta cayennensis (Rich.) Vahl in a murine model. Journal of ethnopharmacology. 2023 Feb; 302(Pt A):115877. doi: 10.1016/j.jep.2022.115877. [PMID: 36336223]
  • Serpil Demirci, Cemalettin Alp, Hüseyin Akşit, Yakup Ulutaş, Ahmet Altay, Esma Yeniçeri, Ekrem Köksal, Nurettin Yaylı. Isolation, characterization and anticancer activity of secondary metabolites from Verbascum speciosum. Chemical biology & drug design. 2023 Feb; ?(?):. doi: 10.1111/cbdd.14211. [PMID: 36756721]
  • Natalia Ritter Ruas, Aline Carvalho Pereira, Luciana Lopes Silva Pereira, Carolina Mesquita Germano, Elaine Fontes Ferreira da Cunha, Alexandre Alves de Carvalho, Osmar Alves Lameira, José Eduardo Brasil Pereira Pinto, Suzan Kelly Vilela Bertolucci. Inhibition of α-Glycosidase by Lippia dulcis Trevir. (Verbenaceae) Preparations, Quantification of Verbascoside, and Study of Its Molecular Docking. Chemistry & biodiversity. 2023 Feb; 20(2):e202200760. doi: 10.1002/cbdv.202200760. [PMID: 36693786]
  • Tongtong Zhu, Wanning Chen, Chunyue Han, Zhijie Gao, Erwei Liu, Xiumei Gao, Zhifei Fu, Lifeng Han. A comprehensive study on the chemical constituents and pharmacokinetics of Erzhi Formula and Jiawei Erzhi Formula based on targeted and untargeted LC-MS analysis. Current drug metabolism. 2023 Jan; ?(?):. doi: 10.2174/1389200224666230130093412. [PMID: 36718973]
  • Shota Takumi, Kairi Hashimoto, Masaru Tomioka, Mina Sato, Weijie He, Yumiko Komatsu, Shunji Aoki, Ryuji Ikeda, Kazuhiro Shiozaki, Tatsuhiko Furukawa, Masaharu Komatsu. Acteoside from Conandron ramondioides Reduces Microcystin-LR Cytotoxicity by Inhibiting Intracellular Uptake Mediated by OATP1B3. Planta medica. 2023 Jan; ?(?):. doi: 10.1055/a-1978-8768. [PMID: 36626925]
  • Dinesh Kumar, Rajeev Kumar Singla, Pooja Sharma, Lutesh Kumar, Navdeep Kaur, Ravi Kumar Dhawan, Shailesh Sharma, Kamal Dua, Rohit Sharma. Phytochemistry and Polypharmacological Potential of Colebrookea oppositifolia Smith. Current topics in medicinal chemistry. 2023; 23(5):334-348. doi: 10.2174/1568026623666221202112414. [PMID: 36476430]
  • Bianca R Silva, José R V Silva. Mechanisms of action of non-enzymatic antioxidants to control oxidative stress during in vitro follicle growth, oocyte maturation, and embryo development. Animal reproduction science. 2022 Dec; 249(?):107186. doi: 10.1016/j.anireprosci.2022.107186. [PMID: 36638648]
  • Vajira Asela Agampodi, Peter Katavic, Christopher Collet, Trudi Collet. Antibacterial and Anti-inflammatory Activity of Extracts and Major Constituents Derived from Stachytarpheta indica Linn. Leaves and Their Potential Implications for Wound Healing. Applied biochemistry and biotechnology. 2022 Dec; 194(12):6213-6254. doi: 10.1007/s12010-021-03635-4. [PMID: 35904675]
  • Yan-Jie Qu, Min-Rui Ding, Chao Gu, Li-Min Zhang, Rong-Rong Zhen, Jin-Fang Chen, Bing Hu, Hong-Mei An. Acteoside and ursolic acid synergistically protects H2O2-induced neurotrosis by regulation of AKT/mTOR signalling: from network pharmacology to experimental validation. Pharmaceutical biology. 2022 Dec; 60(1):1751-1761. doi: 10.1080/13880209.2022.2098344. [PMID: 36102631]
  • Patrícia Matos, António Paranhos, Maria Teresa Batista, Artur Figueirinha. Synergistic Effect of DIBOA and Verbascoside from Acanthus mollis Leaf on Tyrosinase Inhibition. International journal of molecular sciences. 2022 Nov; 23(21):. doi: 10.3390/ijms232113536. [PMID: 36362321]
  • Sibashish Kityania, Rajat Nath, Deepa Nath, Jayanta Kumar Patra, Anupam Das Talukdar. Acteoside (Verbascoside): A prospective therapeutic alternative against Hepatocellular Carcinoma by inhibiting the expression of AXL, FGFR, BRAF, TIE2 and RAF1 targets. Combinatorial chemistry & high throughput screening. 2022 Oct; ?(?):. doi: 10.2174/1386207326666221031121426. [PMID: 36321230]
  • Prashanta Kumar Deb, Biswatrish Sarkar. Seasonal variation of verbascoside as a principal phenolic compound linked with antioxidant potentials of Clerodendrum glandulosum Lindl. leaves. Natural product research. 2022 Sep; 36(17):4421-4425. doi: 10.1080/14786419.2021.1979542. [PMID: 34541973]
  • Junjie Zhu, Gang Li, Jing Zhou, Zhiyong Xu, Jing Xu. Cytoprotective effects and antioxidant activities of acteoside and various extracts of Clerodendrum cyrtophyllum Turcz leaves against t-BHP induced oxidative damage. Scientific reports. 2022 07; 12(1):12630. doi: 10.1038/s41598-022-17038-w. [PMID: 35879416]
  • Shanshan Chen, Honghan Liu, Shimiao Wang, Hongbo Jiang, Le Gao, Lu Wang, Lesheng Teng, Chunyue Wang, Di Wang. The Neuroprotection of Verbascoside in Alzheimer's Disease Mediated through Mitigation of Neuroinflammation via Blocking NF-κB-p65 Signaling. Nutrients. 2022 Mar; 14(7):. doi: 10.3390/nu14071417. [PMID: 35406030]
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