Tetramethrin (BioDeep_00000002271)
Secondary id: BioDeep_00001867697
human metabolite blood metabolite
代谢物信息卡片
化学式: C19H25NO4 (331.1783)
中文名称: 胺菊酯, 四甲硫氨酸
谱图信息:
最多检出来源 Homo sapiens(plant) 46.43%
分子结构信息
SMILES: CC(=CC1C(C1(C)C)C(=O)OCN2C(=O)C3=C(C2=O)CCCC3)C
InChI: InChI=1S/C19H25NO4/c1-11(2)9-14-15(19(14,3)4)18(23)24-10-20-16(21)12-7-5-6-8-13(12)17(20)22/h9,14-15H,5-8,10H2,1-4H3
描述信息
P - Antiparasitic products, insecticides and repellents > P03 - Ectoparasiticides, incl. scabicides, insecticides and repellents > P03B - Insecticides and repellents > P03BA - Pyrethrines
D010575 - Pesticides > D007306 - Insecticides > D011722 - Pyrethrins
D016573 - Agrochemicals
同义名列表
10 个代谢物同义名
2,2-Dimethyl-3-(2-methylpropenyl)cyclopropanecarboxylic acid, ester with N-(hydroxymethyl)-1-cyclo hexene 1,2-dicarboximide; (1,3-dioxo-2,3,4,5,6,7-hexahydro-1H-isoindol-2-yl)methyl 2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carboxylate; Tetramethrin; Phthalthrin; Neo-pynamin; Neopinamine; Neopinamin; Neopynamin; Tetramethrin; Tetramethrin
数据库引用编号
15 个数据库交叉引用编号
- ChEBI: CHEBI:39397
- KEGG: C18373
- KEGGdrug: D07368
- PubChem: 83975
- HMDB: HMDB0258915
- Metlin: METLIN72185
- DrugBank: DB13752
- ChEMBL: CHEMBL1788386
- Wikipedia: Tetramethrin
- chemspider: 75773
- CAS: 66525-27-7
- CAS: 7696-12-0
- PMhub: MS000002260
- PubChem: 124489047
- KNApSAcK: 39397
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yang Li, Mijia Li, Shiyi Duan, Sijie Zhang, Huiqiang Lu, Xinchun Guo, Keyuan Zhong. d-Tetramethrin causes zebrafish hepatotoxicity by inducing oxidative stress and inhibiting cell proliferation.
Toxicology and applied pharmacology.
2024 Jan; 483(?):116817. doi:
10.1016/j.taap.2024.116817. [PMID: 38215995] - Laura Bille, Giovanni Binato, Claudio Gabrieli, Amedeo Manfrin, Francesco Pascoli, Tobia Pretto, Anna Toffan, Manuela Dalla Pozza, Roberto Angeletti, Giuseppe Arcangeli. First report of a fish kill episode caused by pyrethroids in Italian freshwater.
Forensic science international.
2017 Dec; 281(?):176-182. doi:
10.1016/j.forsciint.2017.10.040. [PMID: 29190591] - Oguzhan Yavuz, Abdurrahman Aksoy, Yavuz Kursad Das, Mustafa Yavuz Gulbahar, Dilek Guvenc, Enes Atmaca, Fatma Gul Yarim, Metin Cenesiz. Subacute oral toxicity of combinations of selected synthetic pyrethroids, piperonyl butoxide, and tetramethrin in rats.
Toxicology and industrial health.
2015 Apr; 31(4):289-97. doi:
10.1177/0748233712469651. [PMID: 23299193] - Ivana Klopčič, Katra Kolšek, Marija Sollner Dolenc. Glucocorticoid-like activity of propylparaben, butylparaben, diethylhexyl phthalate and tetramethrin mixtures studied in the MDA-kb2 cell line.
Toxicology letters.
2015 Jan; 232(2):376-83. doi:
10.1016/j.toxlet.2014.11.019. [PMID: 25448277] - John E Casida. The greening of pesticide-environment interactions: some personal observations.
Environmental health perspectives.
2012 Apr; 120(4):487-93. doi:
10.1289/ehp.1104405. [PMID: 22472325] - Marianna Marangi, Vincenzo Morelli, Sandra Pati, Antonio Camarda, Maria Assunta Cafiero, Annunziata Giangaspero. Acaricide residues in laying hens naturally infested by red mite Dermanyssus gallinae.
PloS one.
2012; 7(2):e31795. doi:
10.1371/journal.pone.0031795. [PMID: 22363736] - Yangyang Liu, Hanying Zhang, Chuanling Qiao, Xiping Lu, Feng Cui. Correlation between carboxylesterase alleles and insecticide resistance in Culex pipiens complex from China.
Parasites & vectors.
2011 Dec; 4(?):236. doi:
10.1186/1756-3305-4-236. [PMID: 22177233] - Yoshie Hata, Stefanie Zimmermann, Melanie Quitschau, Marcel Kaiser, Matthias Hamburger, Michael Adams. Antiplasmodial and antitrypanosomal activity of pyrethrins and pyrethroids.
Journal of agricultural and food chemistry.
2011 Sep; 59(17):9172-6. doi:
10.1021/jf201776z. [PMID: 21786822] - Chiu-Hwa Lin, Cheing-Tong Yan, Ponnusamy Vinoth Kumar, Hong-Ping Li, Jen-Fon Jen. Determination of pyrethroid metabolites in human urine using liquid phase microextraction coupled in-syringe derivatization followed by gas chromatography/electron capture detection.
Analytical and bioanalytical chemistry.
2011 Aug; 401(3):927-37. doi:
10.1007/s00216-011-5122-0. [PMID: 21667061] - Edith Berger-Preiss, Wolfgang Koch, Susanne Gerling, Heiko Kock, Klaus E Appel. Use of biocidal products (insect sprays and electro-vaporizer) in indoor areas--exposure scenarios and exposure modeling.
International journal of hygiene and environmental health.
2009 Sep; 212(5):505-18. doi:
10.1016/j.ijheh.2009.02.001. [PMID: 19345645] - Marlene Martin, Kristina Rodriguez, Miguel Sánchez-Sauco, Gerardo Zambudio-Carmona, Juan Antonio Ortega-García. Household exposure to pesticides and bladder exstrophy in a newborn baby boy: a case report and review of the literature.
Journal of medical case reports.
2009 Mar; 3(?):6626. doi:
10.1186/1752-1947-3-6626. [PMID: 19830118] - Gabriele Leng, Wolfgang Gries, Sami Selim. Biomarker of pyrethrum exposure.
Toxicology letters.
2006 Apr; 162(2-3):195-201. doi:
10.1016/j.toxlet.2005.09.030. [PMID: 16257148] - Gabriele Leng, Wolfgang Gries. Simultaneous determination of pyrethroid and pyrethrin metabolites in human urine by gas chromatography-high resolution mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2005 Jan; 814(2):285-94. doi:
10.1016/j.jchromb.2004.10.044. [PMID: 15639450] - Bobby L Loper, Kim A Anderson. Determination of pyrethrin and pyrethroid pesticides in urine and water matrixes by liquid chromatography with diode array detection.
Journal of AOAC International.
2003 Nov; 86(6):1236-40. doi:
. [PMID: 14979708] - I V Tabarean, T Narahashi. Potent modulation of tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels by the type II pyrethroid deltamethrin.
The Journal of pharmacology and experimental therapeutics.
1998 Mar; 284(3):958-65. doi:
. [PMID: 9495855] - Y Tomigahara, M Onogi, K Saito, H Kaneko, I Nakatsuka, S Yamane. Metabolism of tetramethrin isomers in rat: IV. Tissues responsible for formation of reduced and hydrated metabolites.
Xenobiotica; the fate of foreign compounds in biological systems.
1997 Sep; 27(9):961-71. doi:
10.1080/004982597240127. [PMID: 9381736] - Y Tomigahara, M Mori, K Shiba, N Isobe, H Kaneko, I Nakatsuka, H Yamada. Metabolism of tetramethrin isomers in rat: II. Identification and quantitation of metabolites.
Xenobiotica; the fate of foreign compounds in biological systems.
1994 Dec; 24(12):1205-14. doi:
10.3109/00498259409038676. [PMID: 7771107] - Y Tomigahara, M Mori, K Shiba, N Isobe, H Kaneko, I Nakatsuka, H Yamada. Metabolism of tetramethrin isomers in rat. I. Identification of a sulphonic acid type of conjugate and reduced metabolites.
Xenobiotica; the fate of foreign compounds in biological systems.
1994 May; 24(5):473-84. doi:
10.3109/00498259409043250. [PMID: 8079506] - S Harada, I Nishimoto. Possible requirement of serum progression factors for transformation of BALB/c 3T3 fibroblasts by v-ras p21.
FEBS letters.
1991 Dec; 295(1-3):59-62. doi:
10.1016/0014-5793(91)81384-k. [PMID: 1765169] - I Kojima, M Kitaoka, E Ogata. Insulin-like growth factor-I stimulates diacylglycerol production via multiple pathways in Balb/c 3T3 cells.
The Journal of biological chemistry.
1990 Oct; 265(28):16846-50. doi:
10.1016/s0021-9258(17)44838-1. [PMID: 2120207] - I S Silver, W C Dauterman. The toxicokinetics of (1R, cis)- and (1R, trans)- tetramethrin in the isolated perfused rat liver.
Xenobiotica; the fate of foreign compounds in biological systems.
1989 May; 19(5):509-19. doi:
10.3109/00498258909042290. [PMID: 2750207] - I S Silver, W C Dauterman. The pharmacokinetics and metabolism of (1R, cis)- and (1R, trans)-tetramethrin in rats.
Xenobiotica; the fate of foreign compounds in biological systems.
1989 Mar; 19(3):301-14. doi:
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