Cyclohexanecarboxylic acid (BioDeep_00000002200)

 

Secondary id: BioDeep_00001867813

human metabolite PANOMIX_OTCML-2023 Endogenous natural product


代谢物信息卡片


Cyclohexanecarboxylic acid, sodium salt, 11C-labeled

化学式: C7H12O2 (128.0837)
中文名称: 环已羧酸, 环己甲酸, 环己烷羧酸
谱图信息: 最多检出来源 Homo sapiens(feces) 32.28%

分子结构信息

SMILES: C1CCC(CC1)C(=O)O
InChI: InChI=1S/C7H12O2/c8-7(9)6-4-2-1-3-5-6/h6H,1-5H2,(H,8,9)



数据库引用编号

26 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 MTRNR2L5, NFE2L2, PPP2CA, PRL, RP2
Peripheral membrane protein 2 CTSK, SLC27A2
Endoplasmic reticulum membrane 2 DGAT1, SLC27A2
Nucleus 4 JUND, NFE2L2, PPP2CA, PRL
cytosol 6 ACP5, LEP, NFE2L2, PPP2CA, SLC27A2, TNFRSF11A
dendrite 1 GRM7
nuclear body 1 RP2
centrosome 1 NFE2L2
nucleoplasm 6 ACSF3, CTSK, JUND, NFE2L2, PRL, RP2
RNA polymerase II transcription regulator complex 3 JUND, NFE2L2, PRL
Cell membrane 7 CALCR, CTSK, GRM4, GRM7, RP2, SLC27A2, TACR2
Lipid-anchor 1 RP2
Cytoplasmic side 1 RP2
Multi-pass membrane protein 6 CALCR, DGAT1, GRM4, GRM7, SLC27A2, TACR2
Synapse 1 PPP2CA
cell cortex 1 GRM7
dendritic shaft 1 GRM7
Golgi apparatus 2 NFE2L2, RP2
Golgi membrane 1 INS
Cytoplasm, cytosol 1 NFE2L2
Lysosome 2 ACP5, CTSK
Presynapse 1 GRM4
acrosomal vesicle 1 CALCR
plasma membrane 11 CALCR, CTSK, DGAT1, GRM4, GRM7, NFE2L2, PPP2CA, RP2, SLC27A2, TACR2, TNFRSF11A
presynaptic active zone 1 GRM7
Membrane 7 ACP5, CALCR, DGAT1, GRM4, GRM7, PPP2CA, SLC27A2
apical plasma membrane 1 CTSK
axon 2 CALCR, GRM7
extracellular exosome 4 MMP9, PPP2CA, RP2, SLC27A2
extracellular space 5 CTSK, INS, LEP, MMP9, PRL
lysosomal lumen 1 CTSK
mitochondrion 3 ACSF3, MTRNR2L5, PPP2CA
intracellular membrane-bounded organelle 1 CTSK
Single-pass type I membrane protein 1 TNFRSF11A
Secreted 5 CTSK, INS, LEP, MTRNR2L5, PRL
extracellular region 6 CTSK, INS, LEP, MMP9, MTRNR2L5, PRL
mitochondrial matrix 1 ACSF3
Extracellular side 1 CTSK
transcription regulator complex 1 JUND
Cell projection, cilium 1 RP2
external side of plasma membrane 2 CTSK, TNFRSF11A
Secreted, extracellular space, extracellular matrix 1 MMP9
actin cytoskeleton 1 CNN1
cytoplasmic vesicle 2 GRM4, RP2
microtubule cytoskeleton 1 PPP2CA
postsynaptic membrane 1 GRM7
Apical cell membrane 1 CTSK
Membrane raft 2 PPP2CA, TNFRSF11A
focal adhesion 1 CNN1
peroxisomal membrane 1 SLC27A2
collagen-containing extracellular matrix 1 MMP9
receptor complex 1 GRM7
ciliary basal body 1 RP2
cilium 2 CALCR, RP2
chromatin 3 JUND, NFE2L2, PRL
mediator complex 1 NFE2L2
cytoskeleton 1 CNN1
centriole 1 RP2
spindle pole 1 PPP2CA
sperm midpiece 1 TACR2
Cytoplasm, cytoskeleton, spindle pole 1 PPP2CA
sperm flagellum 1 TACR2
endosome lumen 2 INS, PRL
Chromosome, centromere 1 PPP2CA
specific granule membrane 2 DGAT1, SLC27A2
Peroxisome membrane 1 SLC27A2
Microsome 1 SLC27A2
ficolin-1-rich granule lumen 1 MMP9
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 INS, SLC27A2
transcription repressor complex 1 JUND
tertiary granule lumen 1 MMP9
transport vesicle 1 INS
FAR/SIN/STRIPAK complex 1 PPP2CA
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
chromosome, centromeric region 1 PPP2CA
protein-DNA complex 1 NFE2L2
[Isoform 1]: Cell membrane 1 TNFRSF11A
amylin receptor complex 3 1 CALCR
periciliary membrane compartment 1 RP2
transcription factor AP-1 complex 1 JUND
sperm head 1 TACR2
endolysosome lumen 1 CTSK
asymmetric synapse 1 GRM7
protein serine/threonine phosphatase complex 1 PPP2CA
protein phosphatase type 2A complex 1 PPP2CA
amylin receptor complex 1 1 CALCR
amylin receptor complex 2 1 CALCR
[Isoform RANK-e5a]: Cell membrane 1 TNFRSF11A


文献列表

  • Ludovico Pontoni, Giuseppe d'Antonio, Giovanni Esposito, Massimiliano Fabbricino, Luigi Frunzo, Francesco Pirozzi. Thermal pretreatment of olive mill wastewater for efficient methane production: control of aromatic substances degradation by monitoring cyclohexane carboxylic acid. Environmental technology. 2015 Jul; 36(13-16):1785-94. doi: 10.1080/09593330.2015.1012179. [PMID: 25624137]
  • Masaki Setoguchi, Shin Iimura, Yuuichi Sugimoto, Yoshiyuki Yoneda, Jun Chiba, Toshiyuki Watanabe, Fumihito Muro, Yutaka Iigo, Gensuke Takayama, Mika Yokoyama, Tomoe Taira, Misato Aonuma, Tohru Takashi, Atsushi Nakayama, Nobuo Machinaga. A novel, potent, and orally active VLA-4 antagonist with good aqueous solubility: trans-4-[1-[[2-(5-Fluoro-2-methylphenylamino)-7-fluoro-6-benzoxazolyl]acetyl]-(5S)-[methoxy(methyl)amino]methyl-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylic acid. Bioorganic & medicinal chemistry. 2013 Jan; 21(1):42-61. doi: 10.1016/j.bmc.2012.11.003. [PMID: 23218775]
  • Ch V Ramana, Ch Sasikala, K Arunasri, P Anil Kumar, T N R Srinivas, S Shivaji, P Gupta, J Süling, J F Imhoff. Rubrivivax benzoatilyticus sp. nov., an aromatic, hydrocarbon-degrading purple betaproteobacterium. International journal of systematic and evolutionary microbiology. 2006 Sep; 56(Pt 9):2157-2164. doi: 10.1099/ijs.0.64209-0. [PMID: 16957114]
  • Bengt Andrée, Christer Halldin, Victor W Pike, Roger N Gunn, Hans Olsson, Lars Farde. The PET radioligand [carbonyl-(11)C]desmethyl-WAY-100635 binds to 5-HT(1A) receptors and provides a higher radioactive signal than [carbonyl-(11)C]WAY-100635 in the human brain. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2002 Mar; 43(3):292-303. doi: . [PMID: 11884487]
  • Yasuo Dobashi, Tomofumi Santa, Kazuya Nakagomi, Kazuhiro Imai. An automated analyzer for methylated arginines in rat plasma by high-performance liquid chromatography with post-column fluorescence reaction. The Analyst. 2002 Jan; 127(1):54-9. doi: 10.1039/b106828h. [PMID: 11827396]
  • M Yamada, Y Marui, C Hayashi, Y Miki, S Takemura. New thiocholine ester substrates for the assay of human serum cholinesterase. Clinical chemistry. 2001 Nov; 47(11):1962-6. doi: . [PMID: 11673363]
  • D A Vessey. Isolation and preliminary characterization of the medium-chain fatty acid:CoA ligase responsible for activation of short- and medium-chain fatty acids in colonic mucosa from swine. Digestive diseases and sciences. 2001 Feb; 46(2):438-42. doi: 10.1023/a:1005677521373. [PMID: 11281196]
  • M J Liu, G M Pollack. Pharmacokinetics and pharmacodynamics of valproate analogs in rats. II. Pharmacokinetics of octanoic acid, cyclohexanecarboxylic acid, and 1-methyl-1-cyclohexanecarboxylic acid. Biopharmaceutics & drug disposition. 1993 May; 14(4):325-39. doi: 10.1002/bdd.2510140406. [PMID: 8499583]
  • M J Liu, K L Brouwer, G M Pollack. Pharmacokinetics and pharmacodynamics of valproate analogs in rats. III. Pharmacokinetics of valproic acid, cyclohexanecarboxylic acid, and 1-methyl-1-cyclohexanecarboxylic acid in the bile-exteriorized rat. Drug metabolism and disposition: the biological fate of chemicals. 1992 Nov; 20(6):810-5. doi: . [PMID: 1362931]