Nandrolone decanoate (BioDeep_00000002085)
Secondary id: BioDeep_00001867905
human metabolite blood metabolite Chemicals and Drugs
代谢物信息卡片
(1S,2R,10R,11S,14S,15S)-15-methyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-6-en-14-yl decanoate
化学式: C28H44O3 (428.3290274)
中文名称: 癸酸诺龙
谱图信息:
最多检出来源 Homo sapiens(blood) 4.17%
分子结构信息
SMILES: CCCCCCCCCC(=O)OC1CCC2C1(CCC3C2CCC4=CC(=O)CCC34)C
InChI: InChI=1S/C28H44O3/c1-3-4-5-6-7-8-9-10-27(30)31-26-16-15-25-24-13-11-20-19-21(29)12-14-22(20)23(24)17-18-28(25,26)2/h19,22-26H,3-18H2,1-2H3/t22-,23+,24+,25-,26-,28-/m0/s1
描述信息
Nandrolone decanoate is only found in individuals that have used or taken this drug. It is a C18 steroid with androgenic and anabolic properties. It is generally prepared from alkyl ethers of estradiol to resemble testosterone but less one carbon at the 19 position. It is a schedule III drug in the U.S. Nandrolone is an androgen receptor agonist. The drug bound to the receptor complexes which allows it to enter the nucleus and bind directly to specific nucleotide sequences of the chromosomal DNA. The areas of binding are called hormone response elements (HREs), and influence transcriptional activity of certain genes, producing the androgen effects.
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D045930 - Anabolic Agents
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
D050071 - Bone Density Conservation Agents
同义名列表
13 个代谢物同义名
(1S,2R,10R,11S,14S,15S)-15-methyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-6-en-14-yl decanoate; 19-Nor-4-androstene-17 beta-ol-3-one 17-decanoate; 17 beta-Hydroxyestr-4-en-3-one 17-decanoate; 19-Nortestosterone decanoate; Norandrostenolone decanoate; Nortestosterone decanoate; Nandrolone decanoic acid; Nandrolone decanoate; Deca-Durabolin; Decadurobolin; Decadurabolin; Retabolyl; Retabolil
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:7467
- KEGG: C08154
- KEGGdrug: D00955
- PubChem: 9677
- HMDB: HMDB0015694
- Metlin: METLIN1433
- DrugBank: DB08804
- ChEMBL: CHEMBL1200946
- Wikipedia: Nandrolone decanoate
- MeSH: Nandrolone Decanoate
- chemspider: 9296
- CAS: 360-70-3
- PMhub: MS000001806
- PubChem: 10354
- NIKKAJI: J5.698G
- RefMet: Nandrolone decanoate
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Sofia Zelleroth, Erik Nylander, Ellinor Kjellgren, Alfhild Grönbladh, Mathias Hallberg. Nandrolone decanoate and testosterone undecanoate differently affect stress hormones, neurotransmitter systems, and general activity in the male rat.
Behavioural brain research.
2022 08; 432(?):113971. doi:
10.1016/j.bbr.2022.113971. [PMID: 35738337] - Renan Pozzi, Leandro Fernandes, Vanessa Cavalcante da Silva, Vânia D'Almeida. Nandrolone decanoate and resistance exercise affect body composition and energy metabolism.
Steroids.
2021 10; 174(?):108899. doi:
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Reproductive toxicology (Elmsford, N.Y.).
2021 06; 102(?):98-108. doi:
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Cell reports.
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Steroids.
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