Indinavir (BioDeep_00000002007)

 

Secondary id: BioDeep_00000405865

human metabolite blood metabolite Chemicals and Drugs


代谢物信息卡片


(1(1S,2R),5(S))-2,3,5-Trideoxy-N-(2,3-dihydro-2-hydroxy-1H-inden-1-yl)-5-(2-(((1,1-dimethylethyl)amino)carbonyl)-4-(3-pyridinylmethyl)-1-piperazinyl)-2-(phenylmethyl)-D-erythro-pentonamide

化学式: C36H47N5O4 (613.3627862)
中文名称: 茚地那韦
谱图信息: 最多检出来源 Homo sapiens(blood) 1.61%

分子结构信息

SMILES: CC(C)(C)NC(=O)C1CN(Cc2cccnc2)CCN1CC(O)CC(Cc1ccccc1)C(=O)NC1c2ccccc2CC1O
InChI: InChI=1S/C36H47N5O4/c1-36(2,3)39-35(45)31-24-40(22-26-12-9-15-37-21-26)16-17-41(31)23-29(42)19-28(18-25-10-5-4-6-11-25)34(44)38-33-30-14-8-7-13-27(30)20-32(33)43/h4-15,21,28-29,31-33,42-43H,16-20,22-24H2,1-3H3,(H,38,44)(H,39,45)/t28-,29+,31+,32-,33+/m1/s1

描述信息

Indinavir is only found in individuals that have used or taken this drug. It is a potent and specific HIV protease inhibitor that appears to have good oral bioavailability. [PubChem]Indinavir inhibits the HIV viral protease enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.
CONFIDENCE standard compound; INTERNAL_ID 178; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3668; ORIGINAL_PRECURSOR_SCAN_NO 3666
CONFIDENCE standard compound; INTERNAL_ID 178; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7953; ORIGINAL_PRECURSOR_SCAN_NO 7951
CONFIDENCE standard compound; INTERNAL_ID 178; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7922; ORIGINAL_PRECURSOR_SCAN_NO 7919
CONFIDENCE standard compound; INTERNAL_ID 178; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3684; ORIGINAL_PRECURSOR_SCAN_NO 3682
CONFIDENCE standard compound; INTERNAL_ID 178; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7948; ORIGINAL_PRECURSOR_SCAN_NO 7944
INTERNAL_ID 178; CONFIDENCE standard compound; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3703; ORIGINAL_PRECURSOR_SCAN_NO 3700
CONFIDENCE standard compound; INTERNAL_ID 178; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7958; ORIGINAL_PRECURSOR_SCAN_NO 7956
CONFIDENCE standard compound; INTERNAL_ID 178; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7938; ORIGINAL_PRECURSOR_SCAN_NO 7936
CONFIDENCE standard compound; INTERNAL_ID 178; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3664; ORIGINAL_PRECURSOR_SCAN_NO 3662
CONFIDENCE standard compound; INTERNAL_ID 178; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7884; ORIGINAL_PRECURSOR_SCAN_NO 7882
CONFIDENCE standard compound; INTERNAL_ID 178; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3703; ORIGINAL_PRECURSOR_SCAN_NO 3700
CONFIDENCE standard compound; INTERNAL_ID 178; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3663; ORIGINAL_PRECURSOR_SCAN_NO 3661
CONFIDENCE standard compound; INTERNAL_ID 178; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3661; ORIGINAL_PRECURSOR_SCAN_NO 3659
J - Antiinfectives for systemic use > J05 - Antivirals for systemic use > J05A - Direct acting antivirals > J05AE - Protease inhibitors
D000890 - Anti-Infective Agents > D000998 - Antiviral Agents > D000084762 - Viral Protease Inhibitors
D000890 - Anti-Infective Agents > D000998 - Antiviral Agents > D044966 - Anti-Retroviral Agents
C471 - Enzyme Inhibitor > C783 - Protease Inhibitor > C97366 - HIV Protease Inhibitor
C254 - Anti-Infective Agent > C281 - Antiviral Agent > C1660 - Anti-HIV Agent
D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors

同义名列表

10 个代谢物同义名

(1(1S,2R),5(S))-2,3,5-Trideoxy-N-(2,3-dihydro-2-hydroxy-1H-inden-1-yl)-5-(2-(((1,1-dimethylethyl)amino)carbonyl)-4-(3-pyridinylmethyl)-1-piperazinyl)-2-(phenylmethyl)-D-erythro-pentonamide; (2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-4-{[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]carbamoyl}butyl]-N-tert-butyl-4-(pyridin-3-ylmethyl)piperazine-2-carboxamide; Indinavir, sulfate (1:1); Indinavir sulphate; Sulfate, indinavir; Indinavir Sulfate; Indinavir-d6; Compound J; Indinavir; Crixivan



数据库引用编号

30 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

3 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Julien Allard, Simon Bucher, Julie Massart, Pierre-Jean Ferron, Dounia Le Guillou, Roxane Loyant, Yoann Daniel, Youenn Launay, Nelly Buron, Karima Begriche, Annie Borgne-Sanchez, Bernard Fromenty. Drug-induced hepatic steatosis in absence of severe mitochondrial dysfunction in HepaRG cells: proof of multiple mechanism-based toxicity. Cell biology and toxicology. 2021 04; 37(2):151-175. doi: 10.1007/s10565-020-09537-1. [PMID: 32535746]
  • Wen-Shan Liu, Han-Gao Li, Chuan-Hua Ding, Hai-Xia Zhang, Rui-Rui Wang, Jia-Qiu Li. Screening potential FDA-approved inhibitors of the SARS-CoV-2 major protease 3CLpro through high-throughput virtual screening and molecular dynamics simulation. Aging. 2021 03; 13(5):6258-6272. doi: 10.18632/aging.202703. [PMID: 33678621]
  • Ana P Costa, Michael H Court, Nicolas F Villarino, Neal S Burke, Katrina L Mealey. Canine orosomucoid (alpha-1 acid glycoprotein) variants and their influence on drug plasma protein binding. Journal of veterinary pharmacology and therapeutics. 2021 Jan; 44(1):116-125. doi: 10.1111/jvp.12899. [PMID: 32744755]
  • Mohammad M Ghahremanpour, Julian Tirado-Rives, Maya Deshmukh, Joseph A Ippolito, Chun-Hui Zhang, Israel Cabeza de Vaca, Maria-Elena Liosi, Karen S Anderson, William L Jorgensen. Identification of 14 Known Drugs as Inhibitors of the Main Protease of SARS-CoV-2. ACS medicinal chemistry letters. 2020 Dec; 11(12):2526-2533. doi: 10.1021/acsmedchemlett.0c00521. [PMID: 33324471]
  • Purushothaman Indu, Marimuthu Ragavan Rameshkumar, Narasingam Arunagirinathan, Naif Abdullah Al-Dhabi, Mariadhas Valan Arasu, Savarimuthu Ignacimuthu. Raltegravir, Indinavir, Tipranavir, Dolutegravir, and Etravirine against main protease and RNA-dependent RNA polymerase of SARS-CoV-2: A molecular docking and drug repurposing approach. Journal of infection and public health. 2020 Dec; 13(12):1856-1861. doi: 10.1016/j.jiph.2020.10.015. [PMID: 33168456]
  • Teruhisa S Komatsu, Noriaki Okimoto, Yohei M Koyama, Yoshinori Hirano, Gentaro Morimoto, Yousuke Ohno, Makoto Taiji. Drug binding dynamics of the dimeric SARS-CoV-2 main protease, determined by molecular dynamics simulation. Scientific reports. 2020 10; 10(1):16986. doi: 10.1038/s41598-020-74099-5. [PMID: 33046764]
  • Donald C Hall, Hai-Feng Ji. A search for medications to treat COVID-19 via in silico molecular docking models of the SARS-CoV-2 spike glycoprotein and 3CL protease. Travel medicine and infectious disease. 2020 May; 35(?):101646. doi: 10.1016/j.tmaid.2020.101646. [PMID: 32294562]
  • Usisipho Feleni, Unathi Sidwaba, Hlamulo Makelane, Emmanuel Iwuoha. Core-Shell Palladium Telluride Quantum Dot-Hemethiolate Cytochrome Based Biosensor for Detecting Indinavir Drug. Journal of nanoscience and nanotechnology. 2019 12; 19(12):7974-7981. doi: 10.1166/jnn.2019.16866. [PMID: 31196318]
  • Masoumeh Kurd, Soroor Sadegh Malvajerd, Saeed Rezaee, Mehrdad Hamidi, Katayoun Derakhshandeh. Oral delivery of indinavir using mPEG-PCL nanoparticles: preparation, optimization, cellular uptake, transport and pharmacokinetic evaluation. Artificial cells, nanomedicine, and biotechnology. 2019 Dec; 47(1):2123-2133. doi: 10.1080/21691401.2019.1616553. [PMID: 31155961]
  • Fatma Kalleli, Iness Bettaieb Rebey, Wissem Aidi Wannes, Faycel Boughalleb, Majdi Hammami, Moufida Saidani Tounsi, Mahmoud M'hamdi. Chemical composition and antioxidant potential of essential oil and methanol extract from Tunisian and French fennel (Foeniculum vulgare Mill.) seeds. Journal of food biochemistry. 2019 08; 43(8):e12935. doi: 10.1111/jfbc.12935. [PMID: 31368565]
  • Dan-Dan Tian, Cathrine Leonowens, Emily J Cox, Vanessa González-Pérez, Kosea S Frederick, Yolanda V Scarlett, Michael B Fisher, Mary F Paine. Indinavir Increases Midazolam N-Glucuronidation in Humans: Identification of an Alternate CYP3A Inhibitor Using an In Vitro to In Vivo Approach. Drug metabolism and disposition: the biological fate of chemicals. 2019 07; 47(7):724-731. doi: 10.1124/dmd.119.087007. [PMID: 31028057]
  • Bartłomiej Matłosz, Ewa Pietraszkiewicz, Ewa Firląg-Burkacka, Ewa Grycner, Andrzej Horban, Justyna D Kowalska. Risk factors for kidney disease among HIV-1 positive persons in the methadone program. Clinical and experimental nephrology. 2019 Mar; 23(3):342-348. doi: 10.1007/s10157-018-1644-5. [PMID: 30218298]
  • Mohammad Nasiri, Amir Azadi, Mohammad Reza Saghatchi Zanjani, Mehrdad Hamidi. Indinavir-Loaded Nanostructured Lipid Carriers to Brain Drug Delivery: Optimization, Characterization and Neuropharmacokinetic Evaluation. Current drug delivery. 2019; 16(4):341-354. doi: 10.2174/1567201816666190123124429. [PMID: 30674257]
  • Mohd Sayeed, Sudeep Gautam, Devesh Pratap Verma, Tayyaba Afshan, Tripti Kumari, Arvind Kumar Srivastava, Jimut Kanti Ghosh. A collagen domain-derived short adiponectin peptide activates APPL1 and AMPK signaling pathways and improves glucose and fatty acid metabolisms. The Journal of biological chemistry. 2018 08; 293(35):13509-13523. doi: 10.1074/jbc.ra118.001801. [PMID: 29991592]
  • Kaylee Havenga, Efrem Abay, Lubbe Wiesner, Alvaro Viljoen, Dewald Steyn, Josias Hamman. The In Vitro and In Vivo Effects of Hypoxis hemerocallidea on Indinavir Pharmacokinetics: Modulation of Efflux. Planta medica. 2018 Aug; 84(12-13):895-901. doi: 10.1055/a-0607-2743. [PMID: 29672818]
  • Qing Li, Zhi Ye, Peng Zhu, Dong Guo, Hong Yang, Jin Huang, Wei Zhang, James E Polli, Yan Shu. Indinavir Alters the Pharmacokinetics of Lamivudine Partially via Inhibition of Multidrug and Toxin Extrusion Protein 1 (MATE1). Pharmaceutical research. 2018 01; 35(1):14. doi: 10.1007/s11095-017-2290-4. [PMID: 29302757]
  • K Yang, C Battista, J L Woodhead, S H Stahl, J T Mettetal, P B Watkins, S Q Siler, B A Howell. Systems pharmacology modeling of drug-induced hyperbilirubinemia: Differentiating hepatotoxicity and inhibition of enzymes/transporters. Clinical pharmacology and therapeutics. 2017 04; 101(4):501-509. doi: 10.1002/cpt.619. [PMID: 28074467]
  • Candace M Reno, Erwin C Puente, Zhenyu Sheng, Dorit Daphna-Iken, Adam J Bree, Vanessa H Routh, Barbara B Kahn, Simon J Fisher. Brain GLUT4 Knockout Mice Have Impaired Glucose Tolerance, Decreased Insulin Sensitivity, and Impaired Hypoglycemic Counterregulation. Diabetes. 2017 03; 66(3):587-597. doi: 10.2337/db16-0917. [PMID: 27797912]
  • Agnes B Fogo, Mark A Lusco, Behzad Najafian, Charles E Alpers. AJKD Atlas of Renal Pathology: Indinavir Nephrotoxicity. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2017 01; 69(1):e3. doi: 10.1053/j.ajkd.2016.11.004. [PMID: 28007196]
  • Sandra Medina-Moreno, Thomas C Dowling, Juan C Zapata, Nhut M Le, Edward Sausville, Joseph Bryant, Robert R Redfield, Alonso Heredia. Targeting of CDK9 with indirubin 3'-monoxime safely and durably reduces HIV viremia in chronically infected humanized mice. PloS one. 2017; 12(8):e0183425. doi: 10.1371/journal.pone.0183425. [PMID: 28817720]
  • Sonya VanPatten, Shan Sun, Mingzhu He, Kai Fan Cheng, Ahmad Altiti, Angelos Papatheodorou, Czeslawa Kowal, Venkatesh Jeganathan, James M Crawford, Ona Bloom, Bruce T Volpe, Christian Grant, Nathalie Meurice, Thomas R Coleman, Betty Diamond, Yousef Al-Abed. Amending HIV Drugs: A Novel Small-Molecule Approach To Target Lupus Anti-DNA Antibodies. Journal of medicinal chemistry. 2016 10; 59(19):8859-8867. doi: 10.1021/acs.jmedchem.6b00694. [PMID: 27603688]
  • Lonette Wallis, Maides Malan, Chrisna Gouws, Dewald Steyn, Suria Ellis, Efrem Abay, Lubbe Wiesner, Daniel P Otto, Josias Hamman. Evaluation of Isolated Fractions of Aloe vera Gel Materials on Indinavir Pharmacokinetics: In vitro and in vivo Studies. Current drug delivery. 2016; 13(3):471-80. doi: 10.2174/1567201813888160302163208. [PMID: 26568138]
  • Carlemi Calitz, Chrisna Gouws, Joe Viljoen, Jan Steenekamp, Lubbe Wiesner, Efrem Abay, Josias Hamman. Herb-Drug Pharmacokinetic Interactions: Transport and Metabolism of Indinavir in the Presence of Selected Herbal Products. Molecules (Basel, Switzerland). 2015 Dec; 20(12):22113-27. doi: 10.3390/molecules201219838. [PMID: 26690396]
  • Z X Lin, C T Che, S S Lee, R C Y Chan, P S P Ip, J M Yang. Sophora flavescens (Ku-Shen) as a booster for antiretroviral therapy through cytochrome P450 3A4 inhibition. Hong Kong medical journal = Xianggang yi xue za zhi. 2015 Dec; 21 Suppl 7(?):S18-21. doi: ". [PMID: 26908268]
  • Yijin Liu, Michael Jann, Chad Vandenberg, Chin B Eap, Shahab A Shamsi. Development of an enantioselective assay for simultaneous separation of venlafaxine and O-desmethylvenlafaxine by micellar electrokinetic chromatography-tandem mass spectrometry: Application to the analysis of drug-drug interaction. Journal of chromatography. A. 2015 Nov; 1420(?):119-28. doi: 10.1016/j.chroma.2015.09.088. [PMID: 26460073]
  • Jennifer P Freeling, Josefin Koehn, Cuiling Shu, Jianguo Sun, Rodney J Y Ho. Anti-HIV drug-combination nanoparticles enhance plasma drug exposure duration as well as triple-drug combination levels in cells within lymph nodes and blood in primates. AIDS research and human retroviruses. 2015 Jan; 31(1):107-14. doi: 10.1089/aid.2014.0210. [PMID: 25402233]
  • Eduardo Milton Ramos-Sanchez, Hiro Goto, Dolores Helena Rodriguez Ferreira Rivero, Thais Mauad, Fernando Nogueira de Souza, Andrea Moreira Monteiro, Magnus Gidlund. In vivo assessment of antiretroviral therapy-associated side effects. Memorias do Instituto Oswaldo Cruz. 2014 Jul; 109(4):484-7. doi: 10.1590/0074-0276130559. [PMID: 25075786]
  • André Mateus, Pär Matsson, Per Artursson. A high-throughput cell-based method to predict the unbound drug fraction in the brain. Journal of medicinal chemistry. 2014 Apr; 57(7):3005-10. doi: 10.1021/jm401963n. [PMID: 24601604]
  • Leslie O Ofori, Thomas A Hilimire, Ryan P Bennett, Nathaniel W Brown, Harold C Smith, Benjamin L Miller. High-affinity recognition of HIV-1 frameshift-stimulating RNA alters frameshifting in vitro and interferes with HIV-1 infectivity. Journal of medicinal chemistry. 2014 Feb; 57(3):723-32. doi: 10.1021/jm401438g. [PMID: 24387306]
  • Igbe Ighodaro, Omogbai Kelly Eric, Oyekan Adebayo. Interactions of PPAR α and GLUT4 in DOCA/salt-induced renal injury in mice. Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria. 2013 Dec; 28(2):127-33. doi: . [PMID: 24937386]
  • Jae H Chang, Emile Plise, Jonathan Cheong, Quynh Ho, Molly Lin. Evaluating the in vitro inhibition of UGT1A1, OATP1B1, OATP1B3, MRP2, and BSEP in predicting drug-induced hyperbilirubinemia. Molecular pharmaceutics. 2013 Aug; 10(8):3067-75. doi: 10.1021/mp4001348. [PMID: 23750830]
  • Aaron N Endsley, Rodney J Y Ho. Enhanced anti-HIV efficacy of indinavir after inclusion in CD4-targeted lipid nanoparticles. Journal of acquired immune deficiency syndromes (1999). 2012 Dec; 61(4):417-24. doi: 10.1097/qai.0b013e3182653c1f. [PMID: 22743598]
  • Haitao Liu, Shuchun Liu, Liangdong Guo, Yonggang Zhang, Langjun Cui, Gang Ding. New furanones from the plant endophytic fungus Pestalotiopsis besseyi. Molecules (Basel, Switzerland). 2012 Nov; 17(12):14015-21. doi: 10.3390/molecules171214015. [PMID: 23187285]
  • Edward P Acosta, Kay L Limoli, Lan Trinh, Neil T Parkin, Jennifer R King, Jodi M Weidler, Ighovwerha Ofotokun, Christos J Petropoulos. Novel method to assess antiretroviral target trough concentrations using in vitro susceptibility data. Antimicrobial agents and chemotherapy. 2012 Nov; 56(11):5938-45. doi: 10.1128/aac.00691-12. [PMID: 22964257]
  • Lisiane Turatti, Eduardo Sprinz, Rosmeri K Lazzaretti, Regina Kuhmmer, Grasiela Agnes, Jussara M Silveira, Rossana P Basso, Cezar A T Pinheiro, Mariângela F Silveira, Silvana de Almeida, Jorge P Ribeiro, Vanessa S Mattevi. Short communication: UGT1A1*28 variant allele is a predictor of severe hyperbilirubinemia in HIV-infected patients on HAART in southern Brazil. AIDS research and human retroviruses. 2012 Sep; 28(9):1015-8. doi: 10.1089/aid.2011.0261. [PMID: 22050734]
  • Magnus G Rasch, Frederik N Engsig, Bo Feldt-Rasmussen, Ole Kirk, Gitte Kronborg, Court Pedersen, Jan Gerstoft, Niels Obel. Renal function and incidence of chronic kidney disease in HIV patients: a Danish cohort study. Scandinavian journal of infectious diseases. 2012 Sep; 44(9):689-96. doi: 10.3109/00365548.2012.673730. [PMID: 22680981]
  • Tulsi Das Mishra, Hemal Kurani, Puran Singhal, Pranav S Shrivastav. Simultaneous quantitation of HIV-protease inhibitors ritonavir, lopinavir and indinavir in human plasma by UPLC-ESI-MS-MS. Journal of chromatographic science. 2012 Aug; 50(7):625-35. doi: 10.1093/chromsci/bms048. [PMID: 22562821]
  • Fawzia H Toulah, Amal A El-Shafei, Hyat S Al-Rashidi. Evaluation of garlic plant and indinavir drug efficacy in the treatment of cryptosporidiosis in experimentally immumosuppressed rats. Journal of the Egyptian Society of Parasitology. 2012 Aug; 42(2):321-8. doi: 10.12816/0006320. [PMID: 23214211]
  • Omer A Raheem, Hossein S Mirheydar, Kerrin Palazzi, Marianne Chenoweth, Charles Lakin, Roger L Sur. Prevalence of nephrolithiasis in human immunodeficiency virus infected patients on the highly active antiretroviral therapy. Journal of endourology. 2012 Aug; 26(8):1095-8. doi: 10.1089/end.2011.0639. [PMID: 22429050]
  • Lene Ryom, Amanda Mocroft, Jens Lundgren. HIV therapies and the kidney: some good, some not so good?. Current HIV/AIDS reports. 2012 Jun; 9(2):111-20. doi: 10.1007/s11904-012-0110-3. [PMID: 22370968]
  • Xiao-Wu Chen, Kevin B Sneed, Si-Yuan Pan, Chuanhai Cao, Jagat R Kanwar, Helen Chew, Shu-Feng Zhou. Herb-drug interactions and mechanistic and clinical considerations. Current drug metabolism. 2012 Jun; 13(5):640-51. doi: 10.2174/1389200211209050640. [PMID: 22292789]
  • Michael W Jann, Vicky Spratlin, Kathryn Momary, Hailing Zhang, David Turner, Scott R Penzak, Alan Wright, Chad VanDenBerg. Lack of a pharmacokinetic drug-drug interaction with venlafaxine extended-release/indinavir and desvenlafaxine extended-release/indinavir. European journal of clinical pharmacology. 2012 May; 68(5):715-21. doi: 10.1007/s00228-011-1180-7. [PMID: 22173281]
  • Shanmugam Saravanan, Madhavan Vidya, Pachamuthu Balakrishnan, Rami Kantor, Sunil S Solomon, David Katzenstein, Nagalingeswaran Kumarasamy, Tokugha Yeptomi, Sathasivam Sivamalar, Samara Rifkin, Kenneth H Mayer, Suniti Solomon. Viremia and HIV-1 drug resistance mutations among patients receiving second-line highly active antiretroviral therapy in Chennai, Southern India. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2012 Apr; 54(7):995-1000. doi: 10.1093/cid/cir967. [PMID: 22323567]
  • Raveen Parboosing, Glenn E M Maguire, Patrick Govender, Hendrik G Kruger. Nanotechnology and the treatment of HIV infection. Viruses. 2012 04; 4(4):488-520. doi: 10.3390/v4040488. [PMID: 22590683]
  • Manish Yadav, Vikas Trivedi, Vivek Upadhyay, Gaurang Shah, Girin A Baxi, Sailendra Goswami, Pranav S Shrivastav. Comparison of extraction procedures for assessment of matrix effect for selective and reliable determination of atazanavir in human plasma by LC-ESI-MS/MS. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2012 Feb; 885-886(?):138-49. doi: 10.1016/j.jchromb.2011.12.031. [PMID: 22265353]
  • Maude Loignon, Hélène Brodeur, Sonia Deschênes, Denis Phaneuf, Pangala V Bhat, Emil Toma. Combination antiretroviral therapy and chronic HIV infection affect serum retinoid concentrations: longitudinal and cross-sectional assessments. AIDS research and therapy. 2012 Feb; 9(?):3. doi: 10.1186/1742-6405-9-3. [PMID: 22296672]
  • Xiaoyan Chu, Zuo Zhang, Jocelyn Yabut, Sarah Horwitz, John Levorse, Xiang-qing Li, Lei Zhu, Harmony Lederman, Rachel Ortiga, John Strauss, Xiaofang Li, Karen A Owens, Jasminka Dragovic, Thomas Vogt, Raymond Evers, Myung K Shin. Characterization of multidrug resistance 1a/P-glycoprotein knockout rats generated by zinc finger nucleases. Molecular pharmacology. 2012 Feb; 81(2):220-7. doi: 10.1124/mol.111.074179. [PMID: 22049154]
  • Evan D Kharasch, Pamela Sheffels Bedynek, Christine Hoffer, Alysa Walker, Dale Whittington. Lack of indinavir effects on methadone disposition despite inhibition of hepatic and intestinal cytochrome P4503A (CYP3A). Anesthesiology. 2012 Feb; 116(2):432-47. doi: 10.1097/aln.0b013e3182423478. [PMID: 22273859]
  • Jia-Ming Yang, Siu-Po Ip, Yanfang Xian, Ming Zhao, Zhi-Xiu Lin, John Hok Keung Yeung, Raphael Chiu Yeung Chan, Shui-Shan Lee, Chun-Tao Che. Impact of the herbal medicine Sophora flavescens on the oral pharmacokinetics of indinavir in rats: the involvement of CYP3A and P-glycoprotein. PloS one. 2012; 7(2):e31312. doi: 10.1371/journal.pone.0031312. [PMID: 22359586]
  • David E Stec, Peter A Hosick, Joey P Granger. Bilirubin, renal hemodynamics, and blood pressure. Frontiers in pharmacology. 2012; 3(?):18. doi: 10.3389/fphar.2012.00018. [PMID: 22347861]
  • Marilia Rita Pinzone, Michelino Di Rosa, Bruno Cacopardo, Giuseppe Nunnari. HIV RNA suppression and immune restoration: can we do better?. Clinical & developmental immunology. 2012; 2012(?):515962. doi: 10.1155/2012/515962. [PMID: 22489250]
  • Pius S Fasinu, Patrick J Bouic, Bernd Rosenkranz. An overview of the evidence and mechanisms of herb-drug interactions. Frontiers in pharmacology. 2012; 3(?):69. doi: 10.3389/fphar.2012.00069. [PMID: 22557968]
  • Kate Buchacz, Rose Baker, Douglas J Ward, Frank J Palella, Joan S Chmiel, Benjamin Young, Bienvenido G Yangco, Richard M Novak, John T Brooks. Trends in Decline of Antiretroviral Resistance among ARV-Experienced Patients in the HIV Outpatient Study: 1999-2008. AIDS research and treatment. 2012; 2012(?):230290. doi: 10.1155/2012/230290. [PMID: 22611484]
  • Chiara Cioni, Elisa Turlizzi, Ugo Zanelli, Giuseppe Oliveri, Pasquale Annunziata. Expression of Tight Junction and Drug Efflux Transporter Proteins in an in vitro Model of Human Blood-Brain Barrier. Frontiers in psychiatry. 2012; 3(?):47. doi: 10.3389/fpsyt.2012.00047. [PMID: 22593745]
  • Antonella Esposito, Marco Floridia, Gabriella d'Ettorre, Daniele Pastori, Alessandra Fantauzzi, Paola Massetti, Giancarlo Ceccarelli, Camilla Ajassa, Vincenzo Vullo, Ivano Mezzaroma. Rate and determinants of treatment response to different antiretroviral combination strategies in subjects presenting at HIV-1 diagnosis with advanced disease. BMC infectious diseases. 2011 Dec; 11(?):341. doi: 10.1186/1471-2334-11-341. [PMID: 22166160]
  • W Todd Cade, Dominic N Reeds, E Turner Overton, Pilar Herrero, Alan D Waggoner, Victor G Davila-Roman, Sherry Lassa-Claxton, Robert J Gropler, Pablo F Soto, Melissa J Krauss, Kevin E Yarasheski, Linda R Peterson. Effects of human immunodeficiency virus and metabolic complications on myocardial nutrient metabolism, blood flow, and oxygen consumption: a cross-sectional analysis. Cardiovascular diabetology. 2011 Dec; 10(?):111. doi: 10.1186/1475-2840-10-111. [PMID: 22151886]
  • Maria Salgado, S Alireza Rabi, Karen A O'Connell, Robert W Buckheit, Justin R Bailey, Amina A Chaudhry, Autumn R Breaud, Mark A Marzinke, William Clarke, Joseph B Margolick, Robert F Siliciano, Joel N Blankson. Prolonged control of replication-competent dual- tropic human immunodeficiency virus-1 following cessation of highly active antiretroviral therapy. Retrovirology. 2011 Dec; 8(?):97. doi: 10.1186/1742-4690-8-97. [PMID: 22141397]
  • L Ene, D Duiculescu, S M Ruta. How much do antiretroviral drugs penetrate into the central nervous system?. Journal of medicine and life. 2011 Nov; 4(4):432-9. doi: NULL. [PMID: 22514580]
  • Yasuo Uchida, Sumio Ohtsuki, Junichi Kamiie, Tetsuya Terasaki. Blood-brain barrier (BBB) pharmacoproteomics: reconstruction of in vivo brain distribution of 11 P-glycoprotein substrates based on the BBB transporter protein concentration, in vitro intrinsic transport activity, and unbound fraction in plasma and brain in mice. The Journal of pharmacology and experimental therapeutics. 2011 Nov; 339(2):579-88. doi: 10.1124/jpet.111.184200. [PMID: 21828264]
  • Dong Hee Na, Hye Young Ji, Eun Ji Park, Myung Sun Kim, Kwang-Hyeon Liu, Hye Suk Lee. Evaluation of metabolism-mediated herb-drug interactions. Archives of pharmacal research. 2011 Nov; 34(11):1829-42. doi: 10.1007/s12272-011-1105-0. [PMID: 22139684]
  • Charlotte Huet, Abdoulaye Ouedraogo, Issouf Konaté, Isidore Traore, François Rouet, Antoinette Kaboré, Anselme Sanon, Philippe Mayaud, Philippe Van de Perre, Nicolas Nagot. Long-term virological, immunological and mortality outcomes in a cohort of HIV-infected female sex workers treated with highly active antiretroviral therapy in Africa. BMC public health. 2011 Sep; 11(?):700. doi: 10.1186/1471-2458-11-700. [PMID: 21917177]
  • Alejandra Borjabad, Susan Morgello, Wei Chao, Seon-Young Kim, Andrew I Brooks, Jacinta Murray, Mary Jane Potash, David J Volsky. Significant effects of antiretroviral therapy on global gene expression in brain tissues of patients with HIV-1-associated neurocognitive disorders. PLoS pathogens. 2011 Sep; 7(9):e1002213. doi: 10.1371/journal.ppat.1002213. [PMID: 21909266]
  • Kandadi Prabhakar, Syed Muzammil Afzal, Putcha Uday Kumar, Ajumeera Rajanna, Veerabrahma Kishan. Brain delivery of transferrin coupled indinavir submicron lipid emulsions--pharmacokinetics and tissue distribution. Colloids and surfaces. B, Biointerfaces. 2011 Sep; 86(2):305-13. doi: 10.1016/j.colsurfb.2011.04.013. [PMID: 21565469]
  • Johann Cailhol, Béatrice Nkurunziza, Hassan Izzedine, Emmanuel Nindagiye, Laurence Munyana, Evelyne Baramperanye, Janvière Nzorijana, Désiré Sakubu, Théodore Niyongabo, Olivier Bouchaud. Prevalence of chronic kidney disease among people living with HIV/AIDS in Burundi: a cross-sectional study. BMC nephrology. 2011 Aug; 12(?):40. doi: 10.1186/1471-2369-12-40. [PMID: 21864389]
  • Humberto H Lara, Elsa N Garza-Treviño, Liliana Ixtepan-Turrent, Dinesh K Singh. Silver nanoparticles are broad-spectrum bactericidal and virucidal compounds. Journal of nanobiotechnology. 2011 Aug; 9(?):30. doi: 10.1186/1477-3155-9-30. [PMID: 21812950]
  • Jiangeng Huang, Nagsen Gautam, Sai Praneeth R Bathena, Upal Roy, JoEllyn McMillan, Howard E Gendelman, Yazen Alnouti. UPLC-MS/MS quantification of nanoformulated ritonavir, indinavir, atazanavir, and efavirenz in mouse serum and tissues. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2011 Aug; 879(23):2332-8. doi: 10.1016/j.jchromb.2011.06.032. [PMID: 21752731]
  • Mark D Lindsley, Nanthawan Mekha, Henry C Baggett, Yupha Surinthong, Rinrapas Autthateinchai, Pongpun Sawatwong, Julie R Harris, Benjamin J Park, Tom Chiller, S Arunmozhi Balajee, Natteewan Poonwan. Evaluation of a newly developed lateral flow immunoassay for the diagnosis of cryptococcosis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2011 Aug; 53(4):321-5. doi: 10.1093/cid/cir379. [PMID: 21810743]
  • Hetal Thakkar, Jitesh Nangesh, Mayur Parmar, Divyakant Patel. Formulation and characterization of lipid-based drug delivery system of raloxifene-microemulsion and self-microemulsifying drug delivery system. Journal of pharmacy & bioallied sciences. 2011 Jul; 3(3):442-8. doi: 10.4103/0975-7406.84463. [PMID: 21966167]
  • Philippe Flandre, Pascal Pugliese, Lise Cuzin, Corinne Isnard Bagnis, Ivan Tack, André Cabié, Isabelle Poizot-Martin, Christine Katlama, Cécile Brunet-François, Yazdan Yazdanpanah, Pierre Dellamonica. Risk factors of chronic kidney disease in HIV-infected patients. Clinical journal of the American Society of Nephrology : CJASN. 2011 Jul; 6(7):1700-7. doi: 10.2215/cjn.09191010. [PMID: 21566114]
  • B Prabhakar, Asima Banu, H B Pavithra, P Chandrashekhara, Suresh Sasthri. Immunological failure despite virological suppression in HIV seropositive individuals on antiretroviral therapy. Indian journal of sexually transmitted diseases and AIDS. 2011 Jul; 32(2):94-8. doi: 10.4103/0253-7184.85412. [PMID: 22021970]
  • Mayank Mohan Agarwal, Shwaran K Singh, Ravimohan Mavuduru, Arup K Mandal. Preventive fluid and dietary therapy for urolithiasis: An appraisal of strength, controversies and lacunae of current literature. Indian journal of urology : IJU : journal of the Urological Society of India. 2011 Jul; 27(3):310-9. doi: 10.4103/0970-1591.85423. [PMID: 22022052]
  • S Halde, A Mungantiwar, M Chintamaneni. Simple, precise and accurate HPLC method of analysis for nevirapine suspension from human plasma. Indian journal of pharmaceutical sciences. 2011 Jul; 73(4):416-21. doi: 10.4103/0250-474x.95626. [PMID: 22707826]
  • Chiara Tommasi, Rita Bellagamba, Massimo Tempestilli, Antonio D'Avolio, Anna L Gallo, Jelena Ivanovic, Emanuele Nicastri, Leopoldo P Pucillo, Pasquale Narciso. Marked increase in etravirine and saquinavir plasma concentrations during atovaquone/proguanil prophylaxis. Malaria journal. 2011 May; 10(?):141. doi: 10.1186/1475-2875-10-141. [PMID: 21600016]
  • Aurélie Barrail-Tran, Anne-Marie Taburet, Jean-Marie Poirier. [Evidence-based therapeutic drug monitoring for indinavir]. Therapie. 2011 May; 66(3):239-46. doi: 10.2515/therapie/2011035. [PMID: 21819808]
  • Vaibhav Dubey, Manoj Nahar, Dinesh Mishra, Pradyumna Mishra, N K Jain. Surface structured liposomes for site specific delivery of an antiviral agent-indinavir. Journal of drug targeting. 2011 May; 19(4):258-69. doi: 10.3109/1061186x.2010.499460. [PMID: 20604740]
  • Michael Kovochich, Matthew D Marsden, Jerome A Zack. Activation of latent HIV using drug-loaded nanoparticles. PloS one. 2011 Apr; 6(4):e18270. doi: 10.1371/journal.pone.0018270. [PMID: 21483687]
  • David Burger, Marga Teulen, Jaco Eerland, Anneke Harteveld, Rob Aarnoutse, Daan Touw. The International Interlaboratory Quality Control Program for Measurement of Antiretroviral Drugs in Plasma: a global proficiency testing program. Therapeutic drug monitoring. 2011 Apr; 33(2):239-43. doi: 10.1097/ftd.0b013e31820fa528. [PMID: 21383652]
  • Christina M Wyatt, Qiuhu Shi, James E Novak, Donald R Hoover, Lynda Szczech, Jules Semahore Mugabo, Agnes Binagwaho, Mardge Cohen, Eugene Mutimura, Kathryn Anastos. Prevalence of kidney disease in HIV-infected and uninfected Rwandan women. PloS one. 2011 Mar; 6(3):e18352. doi: 10.1371/journal.pone.0018352. [PMID: 21464937]
  • H Knechten, C Stephan, F A Mosthaf, H Jaeger, A Carganico, T Lutz, K Schewe, C Mayr, E Wolf, E Wellmann, A Tappe. The rainbow cohort: 96 week follow-up of saquinavir-containing regimens in previously antiretroviral therapy (ART)-naive and pre-treated but protease inhibitor (PI)-naive HIV-infected patients. European journal of medical research. 2011 Mar; 16(3):93-100. doi: 10.1186/2047-783x-16-3-93. [PMID: 21486721]
  • Prabhakar Kandadi, Muzammil Afzal Syed, Surendar Goparaboina, Kishan Veerabrahma. Brain specific delivery of pegylated indinavir submicron lipid emulsions. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2011 Mar; 42(4):423-32. doi: 10.1016/j.ejps.2011.01.008. [PMID: 21292000]
  • Simona Verdesca, Giovanni B Fogazzi, Giuseppe Garigali, Piergiorgio Messa, Michel Daudon. Crystalluria: prevalence, different types of crystals and the role of infrared spectroscopy. Clinical chemistry and laboratory medicine. 2011 Mar; 49(3):515-20. doi: 10.1515/cclm.2011.078. [PMID: 21143023]
  • Swetha Bollam, Prabhakar Kandadi, Shashank Sridhar Apte, Kishan Veerabrahma. Development of indinavir submicron lipid emulsions loaded with lipoamino acids-in vivo pharmacokinetics and brain-specific delivery. AAPS PharmSciTech. 2011 Mar; 12(1):422-30. doi: 10.1208/s12249-011-9604-3. [PMID: 21360313]
  • Luke C Swenson, Graham Pollock, Brian Wynhoven, Theresa Mo, Winnie Dong, Robert S Hogg, Julio S G Montaner, P Richard Harrigan. 'Dynamic range' of inferred phenotypic HIV drug resistance values in clinical practice. PloS one. 2011 Feb; 6(2):e17402. doi: 10.1371/journal.pone.0017402. [PMID: 21390218]
  • Tim R Cressey, Saik Urien, Deborah Hirt, Guttiga Halue, Malee Techapornroong, Chureeratana Bowonwatanuwong, Prattana Leenasirimakul, Jean-Marc Treluyer, Gonzague Jourdain, Marc Lallemant. Influence of body weight on achieving indinavir concentrations within its therapeutic window in HIV-infected Thai patients receiving indinavir boosted with ritonavir. Therapeutic drug monitoring. 2011 Feb; 33(1):25-31. doi: 10.1097/ftd.0b013e3182057f6f. [PMID: 21233689]
  • Pedro Cahn, Julio Montaner, Patrice Junod, Patricia Patterson, Alejandro Krolewiecki, Jaime Andrade-Villanueva, Isabel Cassetti, Juan Sierra-Madero, Arnaldo David Casiró, Raul Bortolozzi, Sergio Horacio Lupo, Nadia Longo, Emmanouil Rampakakis, Nabil Ackad, John S Sampalis. Pilot, randomized study assessing safety, tolerability and efficacy of simplified LPV/r maintenance therapy in HIV patients on the 1 PI-based regimen. PloS one. 2011; 6(8):e23726. doi: 10.1371/journal.pone.0023726. [PMID: 21886816]
  • Ryan D Cooper, Marcello Tonelli. Renal disease associated with antiretroviral therapy in the treatment of HIV. Nephron. Clinical practice. 2011; 118(3):c262-8. doi: 10.1159/000321646. [PMID: 21212689]
  • Prema Menezes, William C Miller, David A Wohl, Adaora A Adimora, Peter A Leone, William C Miller, Joseph J Eron. Does HAART efficacy translate to effectiveness? Evidence for a trial effect. PloS one. 2011; 6(7):e21824. doi: 10.1371/journal.pone.0021824. [PMID: 21765918]
  • Monica M Davis, Francisco J Alvarez, Kicki Ryman, Åsa A Holm, Per O Ljungdahl, Ylva Engström. Wild-type Drosophila melanogaster as a model host to analyze nitrogen source dependent virulence of Candida albicans. PloS one. 2011; 6(11):e27434. doi: 10.1371/journal.pone.0027434. [PMID: 22110651]
  • Md Sarfaraj Hussain. Patient counseling about herbal-drug interactions. African journal of traditional, complementary, and alternative medicines : AJTCAM. 2011; 8(5 Suppl):152-63. doi: 10.4314/ajtcam.v8i5s.8. [PMID: 22754069]
  • Offie P Soldin, Sarah H Chung, Donald R Mattison. Sex differences in drug disposition. Journal of biomedicine & biotechnology. 2011; 2011(?):187103. doi: 10.1155/2011/187103. [PMID: 21403873]
  • Takeshi Nishijima, Hirokazu Komatsu, Hiroyuki Gatanaga, Takahiro Aoki, Koji Watanabe, Ei Kinai, Haruhito Honda, Junko Tanuma, Hirohisa Yazaki, Kunihisa Tsukada, Miwako Honda, Katsuji Teruya, Yoshimi Kikuchi, Shinichi Oka. Impact of small body weight on tenofovir-associated renal dysfunction in HIV-infected patients: a retrospective cohort study of Japanese patients. PloS one. 2011; 6(7):e22661. doi: 10.1371/journal.pone.0022661. [PMID: 21799928]
  • Richard C Hresko, Paul W Hruz. HIV protease inhibitors act as competitive inhibitors of the cytoplasmic glucose binding site of GLUTs with differing affinities for GLUT1 and GLUT4. PloS one. 2011; 6(9):e25237. doi: 10.1371/journal.pone.0025237. [PMID: 21966466]
  • Jacques Gasnault, Dominique Costagliola, Houria Hendel-Chavez, Anne Dulioust, Sophie Pakianather, Anne-Aurélie Mazet, Marie-Ghislaine de Goer de Herve, Rémi Lancar, Anne-Sophie Lascaux, Lydie Porte, Jean-François Delfraissy, Yassine Taoufik. Improved survival of HIV-1-infected patients with progressive multifocal leukoencephalopathy receiving early 5-drug combination antiretroviral therapy. PloS one. 2011; 6(6):e20967. doi: 10.1371/journal.pone.0020967. [PMID: 21738597]
  • X-W Chen, E S Serag, K B Sneed, J Liang, H Chew, S-Y Pan, S-F Zhou. Clinical herbal interactions with conventional drugs: from molecules to maladies. Current medicinal chemistry. 2011; 18(31):4836-50. doi: 10.2174/092986711797535317. [PMID: 21919844]
  • Laura J Else, Stephen Taylor, David J Back, Saye H Khoo. Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: the male and female genital tract. Antiviral therapy. 2011; 16(8):1149-67. doi: 10.3851/imp1919. [PMID: 22155899]
  • Peter S Kim, Christian Woods, Lauren Dutcher, Patrick Georgoff, Alice Rosenberg, Jo Ann M Mican, Jeffrey B Kopp, Margo A Smith, Colleen Hadigan. Increased prevalence of albuminuria in HIV-infected adults with diabetes. PloS one. 2011; 6(9):e24610. doi: 10.1371/journal.pone.0024610. [PMID: 21931772]
  • Pierre Delobel, Adrien Saliou, Florence Nicot, Martine Dubois, Stéphanie Trancart, Philippe Tangre, Jean-Pierre Aboulker, Anne-Marie Taburet, Jean-Michel Molina, Patrice Massip, Bruno Marchou, Jacques Izopet. Minor HIV-1 variants with the K103N resistance mutation during intermittent efavirenz-containing antiretroviral therapy and virological failure. PloS one. 2011; 6(6):e21655. doi: 10.1371/journal.pone.0021655. [PMID: 21738752]
  • Robert Kalyesubula, Mark A Perazella. Nephrotoxicity of HAART. AIDS research and treatment. 2011; 2011(?):562790. doi: 10.1155/2011/562790. [PMID: 21860787]
  • Andréia M Menezes, Jorge Torelly, Lúcia Real, Mônica Bay, Julia Poeta, Eduardo Sprinz. Prevalence and risk factors associated to chronic kidney disease in HIV-infected patients on HAART and undetectable viral load in Brazil. PloS one. 2011; 6(10):e26042. doi: 10.1371/journal.pone.0026042. [PMID: 22022501]