Ticarcillin (BioDeep_00000001974)
Secondary id: BioDeep_00001868066
human metabolite blood metabolite Chemicals and Drugs
代谢物信息卡片
(2S,5R,6R)-6-{[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
化学式: C15H16N2O6S2 (384.0449756)
中文名称: 替卡西林
谱图信息:
最多检出来源 Homo sapiens(blood) 98.96%
分子结构信息
SMILES: CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CSC=C3)C(=O)O)C(=O)O)C
InChI: InChI=1S/C15H16N2O6S2/c1-15(2)9(14(22)23)17-11(19)8(12(17)25-15)16-10(18)7(13(20)21)6-3-4-24-5-6/h3-5,7-9,12H,1-2H3,(H,16,18)(H,20,21)(H,22,23)/t7-,8-,9+,12-/m1/s1
描述信息
Ticarcillin is only found in individuals that have used or taken this drug. It is an antibiotic derived from penicillin similar to carbenicillin in action.Ticarcillins antibiotic properties arise from its ability to prevent cross-linking of peptidoglycan during cell wall synthesis when the bacteria tries to divide, causing death.
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01C - Beta-lactam antibacterials, penicillins > J01CA - Penicillins with extended spectrum
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D010406 - Penicillins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic
同义名列表
24 个代谢物同义名
(2S,5R,6R)-6-{[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; (2S,5R,6R)-6-[(2R)-2-carboxy-2-(thiophen-3-yl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; (2S,5R,6R)-6-{[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; SmithKline beecham brand OF ticarcillin disodium salt; GlaxoSmithKline brand OF ticarcillin disodium salt; SmithKline beecham brand OF ticarcillin disodium; GlaxoSmithKline brand OF ticarcillin disodium; alpha-Carboxy-3-thienylmethylpenicillin; Α-carboxy-3-thienylmethylpenicillin; a-Carboxy-3-thienylmethylpenicillin; CSL Brand OF ticarcillin disodium; Ticarcillin supplement; Disodium, ticarcillin; Ticarcillin disodium; SCHEMBL5047437; Ticarcillinum; Ticarcilline; Ticarcillin; Ticarcilina; Ticillin; Ticarpen; Tarcil; Ticar; TIPC
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:9587
- KEGG: C07139
- KEGGdrug: D08593
- PubChem: 36921
- PubChem: 5471
- HMDB: HMDB0015545
- Metlin: METLIN2851
- DrugBank: DB01607
- ChEMBL: CHEMBL1449
- Wikipedia: Ticarcillin
- MeSH: Ticarcillin
- chemspider: 33876
- CAS: 34787-01-4
- PMhub: MS000001577
- PubChem: 9348
- NIKKAJI: J17.850K
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
3 个相关的物种来源信息
- 7461 - Apis cerana: 10.1371/JOURNAL.PONE.0175573
- 3708 - Brassica napus: 10.3389/FNUT.2022.822033
- 9606 - Homo sapiens: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Moli Wang, Yanxia Gao, Xueli Liu, Jing Zhang, Qiang Wang, Junshan Chang, Lantong Zhang. Determination and pharmacokinetic analysis of ticarcillin disodium-clavulanate potassium for injection in rat plasma by UPLC-ESI-MS/MS.
The Journal of international medical research.
2020 Dec; 48(12):300060520967822. doi:
10.1177/0300060520967822. [PMID: 33356736] - Caleb J P Economou, Jennifer Ordoñez, Steven C Wallis, Brent Richards, Brett McWhinney, Jeffrey Lipman, Jason A Roberts. Ticarcillin and piperacillin adsorption on to polyethersulfone haemodiafilter membranes in an ex-vivo circuit.
International journal of antimicrobial agents.
2020 Sep; 56(3):106058. doi:
10.1016/j.ijantimicag.2020.106058. [PMID: 32590056] - Caleb J P Economou, Jiao Xie, Gregory Comadira, Brent Richards, Mandy Tallott, Steven C Wallis, Jenny Ordoñez, Jeffrey Lipman, Jason A Roberts. Population pharmacokinetics of ticarcillin in critically ill patients receiving extended daily diafiltration.
International journal of antimicrobial agents.
2019 Sep; 54(3):351-355. doi:
10.1016/j.ijantimicag.2019.06.027. [PMID: 31279852] - Grazia Piizzi, David T Parker, Yunshan Peng, Markus Dobler, Anup Patnaik, Som Wattanasin, Eugene Liu, Francois Lenoir, Jill Nunez, John Kerrigan, David McKenney, Colin Osborne, Donghui Yu, Leanne Lanieri, Jade Bojkovic, JoAnn Dzink-Fox, Maria-Dawn Lilly, Elizabeth R Sprague, Yipin Lu, Hongming Wang, Srijan Ranjitkar, Lili Xie, Bing Wang, Meir Glick, Lawrence G Hamann, Ruben Tommasi, Xia Yang, Charles R Dean. Design, Synthesis, and Properties of a Potent Inhibitor of Pseudomonas aeruginosa Deacetylase LpxC.
Journal of medicinal chemistry.
2017 06; 60(12):5002-5014. doi:
10.1021/acs.jmedchem.7b00377. [PMID: 28549219] - P Usarek, K Dobrzaniecka, K Szymanek-Majchrzak, A Sawicka-Grzelak, A Mlynarczyk, M Durlik, M Ciszek, L Paczek, A Chmura, A Kwiatkowski, G Mlynarczyk. Drug Susceptibility Assessment in Stenotrophomonas Maltophilia Strains Isolated From the Blood of Organ Transplantation Recipients in a Warsaw Teaching Hospital During 2011 to 2014.
Transplantation proceedings.
2016 Jun; 48(5):1411-3. doi:
10.1016/j.transproceed.2016.01.072. [PMID: 27496417] - Sophia Lionaki, Konstantinos Panagiotellis, Demetrios Moris, George Daikos, Mina Psyhogiou, Spiridon Vernadakis, Georgios Zavos, John N Boletis. Clostridium difficile infection among kidney transplant recipients: frequency, clinical presentation, and outcome.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.
2015 Mar; 123(3):234-9. doi:
10.1111/apm.12348. [PMID: 25556694] - Micah E Stevens, Paula M Pijut. Agrobacterium-mediated genetic transformation and plant regeneration of the hardwood tree species Fraxinus profunda.
Plant cell reports.
2014 Jun; 33(6):861-70. doi:
10.1007/s00299-014-1562-2. [PMID: 24493252] - A B Bennett, P A Martin, S A Gottlieb, M Govendir. In vitro susceptibilities of feline and canine Escherichia coli and Pseudomonas spp. isolates to ticarcillin and ticarcillin-clavulanic acid.
Australian veterinary journal.
2013 May; 91(5):171-8. doi:
10.1111/avj.12044. [PMID: 23614511] - Aaron T Wolman, Michael R Gionfriddo, Gregory A Heindel, Paran Mukhija, Sarah Witkowski, Ajay Bommareddy, Adam L Vanwert. Organic anion transporter 3 interacts selectively with lipophilic β-lactam antibiotics.
Drug metabolism and disposition: the biological fate of chemicals.
2013 Apr; 41(4):791-800. doi:
10.1124/dmd.112.049569. [PMID: 23344796] - Rachida Kermas, Abdelaziz Touati, Lucien Brasme, Elisabeth Le Magrex-Debar, Sadjia Mehrane, François-Xavier Weill, Christophe De Champs. Characterization of extended-spectrum beta-lactamase-producing Salmonella enterica serotype Brunei and Heidelberg at the Hussein Dey hospital in Algiers (Algeria).
Foodborne pathogens and disease.
2012 Sep; 9(9):803-8. doi:
10.1089/fpd.2012.1159. [PMID: 22871227] - Ivone Vaz-Moreira, Olga C Nunes, Célia M Manaia. Diversity and antibiotic resistance in Pseudomonas spp. from drinking water.
The Science of the total environment.
2012 Jun; 426(?):366-74. doi:
10.1016/j.scitotenv.2012.03.046. [PMID: 22521167] - Xiao-ling Liu, Dai-zhi Peng, Liang Xue, Wen-ting Shu, Xin Zhou, Jing Liu. [Analysis of resistance phenotype and homology of Klebsiella pneumoniae in burn patients].
Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns.
2012 Apr; 28(2):96-100. doi:
. [PMID: 22781319] - Vânia Figueira, Elizabete A Serra, Ivone Vaz-Moreira, Teresa R S Brandão, Célia M Manaia. Comparison of ubiquitous antibiotic-resistant Enterobacteriaceae populations isolated from wastewaters, surface waters and drinking waters.
Journal of water and health.
2012 Mar; 10(1):1-10. doi:
10.2166/wh.2011.002. [PMID: 22361697] - Janak Kishore. Isolation, identification & characterization of Proteus penneri--a missed rare pathogen.
The Indian journal of medical research.
2012 Mar; 135(?):341-5. doi:
. [PMID: 22561620] - Shen Wan, Amanda M Johnson, Illimar Altosaar. Expression of nitrous oxide reductase from Pseudomonas stutzeri in transgenic tobacco roots using the root-specific rolD promoter from Agrobacterium rhizogenes.
Ecology and evolution.
2012 Feb; 2(2):286-97. doi:
10.1002/ece3.74. [PMID: 22423324] - Erdal Erol, Stephan J Locke, Judy K Donahoe, Mary A Mackin, Craig N Carter. Beta-hemolytic Streptococcus spp. from horses: a retrospective study (2000-2010).
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc.
2012 Jan; 24(1):142-7. doi:
10.1177/1040638711434138. [PMID: 22362945] - Izabela Korona-Glowniak, Ewelina Grywalska, Beata Chudzik, Agnieszka Bojarska-Junak, Anna Malm, Jacek Rolinski. Upper respiratory tract colonization by gram-negative rods in patients with chronic lymphocytic leukemia: analysis of risk factors.
TheScientificWorldJournal.
2012; 2012(?):617218. doi:
10.1100/2012/617218. [PMID: 22606052] - Consuelo Esteve, Elena Alcaide, María Dolores Blasco. Aeromonas hydrophila subsp. dhakensis isolated from feces, water and fish in Mediterranean Spain.
Microbes and environments.
2012; 27(4):367-73. doi:
10.1264/jsme2.me12009. [PMID: 22472298] - S Hammami, I Boutiba-Ben Boubaker, R Ghozzi, M Saidani, S Amine, S Ben Redjeb. Nosocomial outbreak of imipenem-resistant Pseudomonas aeruginosa producing VIM-2 metallo-β-lactamase in a kidney transplantation unit.
Diagnostic pathology.
2011 Oct; 6(?):106. doi:
10.1186/1746-1596-6-106. [PMID: 22035284] - Elpis Mantadakis, Aggelos Tsalkidis, Maria Panopoulou, Spyridon Pagkalis, Gregory Tripsianis, Mathew E Falagas, Mathew Falagas, Sophia Kartali-Ktenidou, Athanassios Chatzimichael. Antimicrobial susceptibility of pediatric uropathogens in Thrace, Greece.
International urology and nephrology.
2011 Jun; 43(2):549-55. doi:
10.1007/s11255-010-9768-x. [PMID: 20524067] - Joanna Mokracka, Ryszard Koczura, Konrad Pawłowski, Adam Kaznowski. Resistance patterns and integron cassette arrays of Enterobacter cloacae complex strains of human origin.
Journal of medical microbiology.
2011 Jun; 60(Pt 6):737-743. doi:
10.1099/jmm.0.027979-0. [PMID: 21330416] - Joanna Mokracka, Ryszard Koczura, Lucyna Jabłońska, Adam Kaznowski. Phylogenetic groups, virulence genes and quinolone resistance of integron-bearing Escherichia coli strains isolated from a wastewater treatment plant.
Antonie van Leeuwenhoek.
2011 May; 99(4):817-24. doi:
10.1007/s10482-011-9555-4. [PMID: 21293926] - James E Dombrowski, James C Baldwin, Steve C Alderman, Ruth C Martin. Transformation of Epichloë typhina by electroporation of conidia.
BMC research notes.
2011 Mar; 4(?):46. doi:
10.1186/1756-0500-4-46. [PMID: 21375770] - Iman K Behiry, Emad A Abada, Entsar A Ahmed, Rania S Labeeb. Enteropathogenic Escherichia coli associated with diarrhea in children in Cairo, Egypt.
TheScientificWorldJournal.
2011; 11(?):2613-9. doi:
10.1100/2011/485381. [PMID: 22262949] - Perlinot Herindrainy, Frédérique Randrianirina, Rila Ratovoson, Elisoa Ratsima Hariniana, Yves Buisson, Nathalie Genel, Dominique Decré, Guillaume Arlet, Antoine Talarmin, Vincent Richard. Rectal carriage of extended-spectrum beta-lactamase-producing gram-negative bacilli in community settings in Madagascar.
PloS one.
2011; 6(7):e22738. doi:
10.1371/journal.pone.0022738. [PMID: 21829498] - Eric Gomez, Martha Sanchez, Zonaira Gul, Carl Urban, Noriel Mariano, Robert H K Eng, David B Huang, Tom Chiang. Polymyxin Combination Therapy and the Use of Serum Bactericidal Titers in the Management of KPC-Producing Klebsiella pneumoniae Infections: A Report of 3 Cases.
Case reports in medicine.
2011; 2011(?):659769. doi:
10.1155/2011/659769. [PMID: 22162703] - Brett C McWhinney, Steven C Wallis, Tara Hillister, Jason A Roberts, Jeffrey Lipman, Jacobus P J Ungerer. Analysis of 12 beta-lactam antibiotics in human plasma by HPLC with ultraviolet detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2010 Jul; 878(22):2039-43. doi:
10.1016/j.jchromb.2010.05.027. [PMID: 20561826] - Todisoa Andriatahina, Frédérique Randrianirina, Eliosa Ratsima Hariniana, Antoine Talarmin, Honoré Raobijaona, Yves Buisson, Vincent Richard. High prevalence of fecal carriage of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in a pediatric unit in Madagascar.
BMC infectious diseases.
2010 Jul; 10(?):204. doi:
10.1186/1471-2334-10-204. [PMID: 20624313] - Jeffery T Zobell, Krow Ampofo, Jared Cash, Kent Korgenski, Barbara A Chatfield. High dose intermittent ticarcillin-clavulanate administration in pediatric cystic fibrosis patients.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.
2010 Jul; 9(4):280-3. doi:
10.1016/j.jcf.2010.04.003. [PMID: 20472513] - Mitesh H Patel, Grishma R Trivedi, Sachin M Patel, Mahendra M Vegad. Antibiotic susceptibility pattern in urinary isolates of gram negative bacilli with special reference to AmpC β-lactamase in a tertiary care hospital.
Urology annals.
2010 Jan; 2(1):7-11. doi:
10.4103/0974-7796.62915. [PMID: 20842250] - Tomasz Bogiel, Agnieszka Mikucka, Tomasz Skalski, Eugenia Gospodarek. [Occurrence and susceptibility to antibiotics of carbapenem-resistant Pseudomonas aeruginosa strains between 1998 and 2009].
Medycyna doswiadczalna i mikrobiologia.
2010; 62(3):221-9. doi:
. [PMID: 21114014] - Sara Romano, Fabien Aujoulat, Estelle Jumas-Bilak, Agnès Masnou, Jean-Luc Jeannot, Enevold Falsen, Hélène Marchandin, Corinne Teyssier. Multilocus sequence typing supports the hypothesis that Ochrobactrum anthropi displays a human-associated subpopulation.
BMC microbiology.
2009 Dec; 9(?):267. doi:
10.1186/1471-2180-9-267. [PMID: 20021660] - Manthena V S Varma, Bo Feng, R Scott Obach, Matthew D Troutman, Jonathan Chupka, Howard R Miller, Ayman El-Kattan. Physicochemical determinants of human renal clearance.
Journal of medicinal chemistry.
2009 Aug; 52(15):4844-52. doi:
10.1021/jm900403j. [PMID: 19445515] - Ningxia Du, Paula M Pijut. Agrobacterium-mediated transformation of Fraxinus pennsylvanica hypocotyls and plant regeneration.
Plant cell reports.
2009 Jun; 28(6):915-23. doi:
10.1007/s00299-009-0697-z. [PMID: 19343350] - Judilee Marrow, Julia K Whittington, Mark Mitchell, Lois L Hoyer, Carol Maddox. Prevalence and antibiotic-resistance characteristics of Enterococcus spp. Isolated from free-living and captive raptors in Central Illinois.
Journal of wildlife diseases.
2009 Apr; 45(2):302-13. doi:
10.7589/0090-3558-45.2.302. [PMID: 19395740] - Emilie Laroche, Barbara Pawlak, Thierry Berthe, David Skurnik, Fabienne Petit. Occurrence of antibiotic resistance and class 1, 2 and 3 integrons in Escherichia coli isolated from a densely populated estuary (Seine, France).
FEMS microbiology ecology.
2009 Apr; 68(1):118-30. doi:
10.1111/j.1574-6941.2009.00655.x. [PMID: 19243438] - Ritu Aggarwal, Uma Chaudhary, Rama Sikka. Detection of Extended Spectrum β-lactamase Production Among Uropathogens.
Journal of laboratory physicians.
2009 Jan; 1(1):7-10. doi:
10.4103/0974-2727.44423. [PMID: 21938241] - Pinar Onguru, Ayse Erbay, Hurrem Bodur, Gulseren Baran, Esragul Akinci, Neriman Balaban, Mustafa Aydin Cevik. Imipenem-resistant Pseudomonas aeruginosa: risk factors for nosocomial infections.
Journal of Korean medical science.
2008 Dec; 23(6):982-7. doi:
10.3346/jkms.2008.23.6.982. [PMID: 19119440] - Veronika Steinbauerová, Pavel Neumann, Jirí Macas. Experimental evidence for splicing of intron-containing transcripts of plant LTR retrotransposon Ogre.
Molecular genetics and genomics : MGG.
2008 Nov; 280(5):427-36. doi:
10.1007/s00438-008-0376-8. [PMID: 18762986] - Viren A Javiya, Somsuvra B Ghatak, Kamlesh R Patel, Jagruti A Patel. Antibiotic susceptibility patterns of Pseudomonas aeruginosa at a tertiary care hospital in Gujarat, India.
Indian journal of pharmacology.
2008 Oct; 40(5):230-4. doi:
10.4103/0253-7613.44156. [PMID: 20040963] - H Ben Abdallah, S Noomen, A Ben Elhadj Khélifa, O Sahnoun, A Elargoubi, M Mastouri. [Susceptibility patterns of Pseudomonas aeruginosa strains isolated in the Monastir region, Tunisia].
Medecine et maladies infectieuses.
2008 Oct; 38(10):554-6. doi:
10.1016/j.medmal.2008.05.002. [PMID: 18814981] - R Scott Obach, Franco Lombardo, Nigel J Waters. Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Drug metabolism and disposition: the biological fate of chemicals.
2008 Jul; 36(7):1385-405. doi:
10.1124/dmd.108.020479. [PMID: 18426954] - Magdalena Stoczko, Jean-Marie Frère, Gian Maria Rossolini, Jean-Denis Docquier. Functional diversity among metallo-beta-lactamases: characterization of the CAR-1 enzyme of Erwinia carotovora.
Antimicrobial agents and chemotherapy.
2008 Jul; 52(7):2473-9. doi:
10.1128/aac.01062-07. [PMID: 18443127] - Efstratios Apostolakis, Nikolaos Panagopoulos, Efstratios N Koletsis, James Crockett, Helen Stamou-Kouki, Efrosini Sourgiadaki, Kriton Filos, Dimitrios Dougenis. Influence of ultra-low dose Aprotinin on thoracic surgical operations: a prospective randomized trial.
Journal of cardiothoracic surgery.
2008 Mar; 3(?):14. doi:
10.1186/1749-8090-3-14. [PMID: 18361800] - Gregory Kaler, David M Truong, Akash Khandelwal, Megha Nagle, Satish A Eraly, Peter W Swaan, Sanjay K Nigam. Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members.
The Journal of biological chemistry.
2007 Aug; 282(33):23841-53. doi:
10.1074/jbc.m703467200. [PMID: 17553798] - S Alfandari, C Bonenfant, L Depretere, G Beaucaire. Use of 27 parenteral antimicrobial agents in north of France hospitals.
Medecine et maladies infectieuses.
2007 Feb; 37(2):103-7. doi:
10.1016/j.medmal.2006.10.010. [PMID: 17303361] - E Rodríguez, M M Gamboa, C Rodríguez, P Vargas. [Bacteroides fragilis group in non-diarrheal human feces and its antimicrobial susceptibility].
Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia.
2006 Dec; 19(4):357-62. doi:
. [PMID: 17235405] - Sándor Tóth, Csaba Kiss, Peter Scott, Gabriella Kovács, Seppo Sorvari, Ottó Toldi. Agrobacterium-mediated genetic transformation of the desiccation tolerant resurrection plant Ramonda myconi (L.) Rchb.
Plant cell reports.
2006 May; 25(5):442-9. doi:
10.1007/s00299-005-0083-4. [PMID: 16362301] - Deborah A Samac, Sandra Austin-Phillips. Alfalfa (Medicago sativa L.).
Methods in molecular biology (Clifton, N.J.).
2006; 343(?):301-11. doi:
10.1385/1-59745-130-4:301. [PMID: 16988354] - Rong-Dih Lin, Yi-Ping Chin, Mei-Hsien Lee. Antimicrobial activity of antibiotics in combination with natural flavonoids against clinical extended-spectrum beta-lactamase (ESBL)-producing Klebsiella pneumoniae.
Phytotherapy research : PTR.
2005 Jul; 19(7):612-7. doi:
10.1002/ptr.1695. [PMID: 16161024] - Wendy J Munckhof, John Carney, Gail Neilson, John Neilson, Julia Carroll, Brett McWhinney, Michael Whitby. Continuous infusion of ticarcillin-clavulanate for home treatment of serious infections: clinical efficacy, safety, pharmacokinetics and pharmacodynamics.
International journal of antimicrobial agents.
2005 Jun; 25(6):514-22. doi:
10.1016/j.ijantimicag.2005.02.008. [PMID: 15878264] - G Boulesteix, P Le Dantec, B Chevalier, M Dieng, B Niang, B Diatta. [Role of Musca domestica in the transmission of multiresistant bacteria in the centres of intensive care setting in sub-Saharan Africa].
Annales francaises d'anesthesie et de reanimation.
2005 Apr; 24(4):361-5. doi:
10.1016/j.annfar.2005.01.016. [PMID: 15826786] - Charles A Manire, Robert P Hunter, David E Koch, Lynne Byrd, Howard L Rhinehart. Pharmacokinetics of ticarcillin in the loggerhead sea turtle (Caretta caretta) after single intravenous and intramuscular injections.
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians.
2005 Mar; 36(1):44-53. doi:
10.1638/04-024. [PMID: 17315456] - C Moubareck, F Gavini, L Vaugien, M J Butel, F Doucet-Populaire. Antimicrobial susceptibility of bifidobacteria.
The Journal of antimicrobial chemotherapy.
2005 Jan; 55(1):38-44. doi:
10.1093/jac/dkh495. [PMID: 15574479] - Souad Kalai, Wafa Jouaihia, Faouzia Mahjoubi, Rafiaa Ghozzi, Lamia Thabet, Saida Ben Rejeb, Adnène Hammami, Amel Kechrid, Assia Ben Hassen. [Pseudomonas aeruginosa: a multicentric study of antibiotic resistance (1999-2000)].
La Tunisie medicale.
2004 Dec; 82(12):1070-4. doi:
. [PMID: 15822507] - Maria José Saavedra, Sandra Guedes-Novais, Anabela Alves, Paulo Rema, Marta Tacão, António Correia, Antonio Martínez-Murcia. Resistance to beta-lactam antibiotics in Aeromonas hydrophila isolated from rainbow trout (Oncorhynchus mykiss).
International microbiology : the official journal of the Spanish Society for Microbiology.
2004 Sep; 7(3):207-11. doi:
NULL. [PMID: 15492935] - C Quentin, C Arpin, V Dubois, C André, I Lagrange, I Fischer, J-P Brochet, F Grobost, J Jullin, B Dutilh, G Larribet, P Noury. Antibiotic resistance rates and phenotypes among isolates of Enterobacteriaceae in French extra-hospital practice.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology.
2004 Mar; 23(3):185-93. doi:
10.1007/s10096-003-1081-5. [PMID: 14986156] - Ozay Arikan Akan. [Antibiotic resistance of Acinetobacter baumannii isolates: data from Ibni Sina Hospital for the year 2002].
Mikrobiyoloji bulteni.
2003 Oct; 37(4):241-6. doi:
NULL. [PMID: 14748260] - Chonghua Li, Qiuming Geng, David P Nicolau, Charles H Nightingale. Simultaneous determination of ticarcillin and clavulanate in rabbit serum and tissue cage fluid by liquid chromatography.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2003 Sep; 794(2):227-36. doi:
10.1016/s1570-0232(03)00456-2. [PMID: 12954375] - I M Gonzalez Padilla, K Webb, R Scorza. Early antibiotic selection and efficient rooting and acclimatization improve the production of transgenic plum plants (Prunus domestica L.).
Plant cell reports.
2003 Aug; 22(1):38-45. doi:
10.1007/s00299-003-0648-z. [PMID: 12827433] - D Casassus-Builhé, P Le Bougeant, T Carmois, F Terrier, E Chauveau, J P Armand, B Oddes. [Hepatic inflammatory pseudotumor regressing with antibiotic therapy].
Presse medicale (Paris, France : 1983).
2002 May; 31(18):838-40. doi:
NULL. [PMID: 12148453] - Abdullah Sakarcan, Roxanne Marcille, James Stallworth. Antibiotic-induced recurring interstitial nephritis.
Pediatric nephrology (Berlin, Germany).
2002 Jan; 17(1):50-1. doi:
10.1007/s004670200009. [PMID: 11793135] - E Grafanakis, L Leontides, C Genigeorgis. Seroprevalence and antibiotic sensitivity of serotypes of Salmonella enterica in Greek pig herds.
The Veterinary record.
2001 Mar; 148(13):407-11. doi:
10.1136/vr.148.13.407. [PMID: 11327648] - S D Van Camp, M G Papich, M D Whitacre. Administration of ticarcillin in combination with clavulanic acid intravenously and intrauterinely to clinically normal oestrous mares.
Journal of veterinary pharmacology and therapeutics.
2000 Dec; 23(6):373-8. doi:
10.1046/j.1365-2885.2000.00297.x. [PMID: 11168915] - C J Donskey, J A Hanrahan, R A Hutton, L B Rice. Effect of parenteral antibiotic administration on the establishment of colonization with vancomycin-resistant Enterococcus faecium in the mouse gastrointestinal tract.
The Journal of infectious diseases.
2000 May; 181(5):1830-3. doi:
10.1086/315428. [PMID: 10823795] - P D Lister, V M Gardner, C C Sanders. Clavulanate induces expression of the Pseudomonas aeruginosa AmpC cephalosporinase at physiologically relevant concentrations and antagonizes the antibacterial activity of ticarcillin.
Antimicrobial agents and chemotherapy.
1999 Apr; 43(4):882-9. doi:
10.1128/aac.43.4.882. [PMID: 10103195] - W H Traub, B Leonhard, D Bauer. Stenotrophomonas (Xanthomonas) maltophilia: in vitro susceptibility to selected antimicrobial drugs, single and combined, with and without defibrinated human blood.
Chemotherapy.
1998 Sep; 44(5):293-304. doi:
10.1159/000007126. [PMID: 9732143] - D N Gilbert, B L Lee, R J Dworkin, J L Leggett, H F Chambers, G Modin, M G Täuber, M A Sande. A randomized comparison of the safety and efficacy of once-daily gentamicin or thrice-daily gentamicin in combination with ticarcillin-clavulanate.
The American journal of medicine.
1998 Sep; 105(3):182-91. doi:
10.1016/s0002-9343(98)00244-7. [PMID: 9753020] - S Corvaisier, P H Maire, M Y Bouvier d'Yvoire, X Barbaut, N Bleyzac, R W Jelliffe. Comparisons between antimicrobial pharmacodynamic indices and bacterial killing as described by using the Zhi model.
Antimicrobial agents and chemotherapy.
1998 Jul; 42(7):1731-7. doi:
10.1128/aac.42.7.1731. [PMID: 9661013] - E J Giamarellos-Bourboulis, P Grecka, A Dionyssiou-Asteriou, H Giamarellou. In vitro activity of polyunsaturated fatty acids on Pseudomonas aeruginosa: relationship to lipid peroxidation.
Prostaglandins, leukotrienes, and essential fatty acids.
1998 Apr; 58(4):283-7. doi:
10.1016/s0952-3278(98)90037-0. [PMID: 9654401] - S Maraki, D Bafaloukos, I Chatzinikolaou, G Datseris, G Samonis. Gut colonization of mice by yeast: effects of methylprednisolone and antibiotics.
Hepato-gastroenterology.
1998 Jan; 45(19):119-22. doi:
. [PMID: 9496499] - E Cheftel, A Spiegel, G Bornert, E Morell, A Michel, Y Buisson. [Toxic food infection caused by Shigella flexneri in a military unit].
Sante (Montrouge, France).
1997 Sep; 7(5):295-9. doi:
NULL. [PMID: 9480034] - Y H Li, T Itoh, Y Tsuda, M Ishida, N Watanabe, H Shimada, H Yamada. Determination of ticarcillin epimers in plasma and urine with high-performance liquid chromatography.
Journal of chromatography. B, Biomedical sciences and applications.
1997 Jun; 694(1):145-52. doi:
10.1016/s0378-4347(97)00123-0. [PMID: 9234857] - D E Nix, J K Thomas, W T Symonds, J M Spivey, J H Wilton, N C Gagliardi, J J Schentag. Assessment of the enzymuria resulting from gentamicin alone and combinations of gentamicin with various beta-lactam antibiotics.
The Annals of pharmacotherapy.
1997 Jun; 31(6):696-703. doi:
10.1177/106002809703100605. [PMID: 9184707] - M A Pfaller, R N Jones. In vitro evaluation of contemporary beta-lactam drugs tested against viridans group and beta-haemolytic streptococci.
Diagnostic microbiology and infectious disease.
1997 Apr; 27(4):151-4. doi:
10.1016/s0732-8893(97)00032-1. [PMID: 9154412] - M E Klepser, M N Marangos, Z Zhu, D P Nicolau, R Quintiliani, C H Nightingale. Comparison of the bactericidal activities of piperacillin-tazobactam, ticarcillin-clavulanate, and ampicillin-sulbactam against clinical isolates of Bacteroides fragilis, Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa.
Antimicrobial agents and chemotherapy.
1997 Feb; 41(2):435-9. doi:
10.1128/aac.41.2.435. [PMID: 9021203] - Z Zhu, D W Xuan, C H Nightingale. Modification of an ion-paired high pressure liquid chromatography for ticarcillin in human serum.
Zhongguo yao li xue bao = Acta pharmacologica Sinica.
1996 Sep; 17(5):395-8. doi:
NULL. [PMID: 9863157] - P J Larkin, J M Gibson, U Mathesius, J J Weinman, E Gartner, E Hall, G J Tanner, B G Rolfe, M A Djordjevic. Transgenic white clover. Studies with the auxin-responsive promoter, GH3, in root gravitropism and lateral root development.
Transgenic research.
1996 Sep; 5(5):325-35. doi:
10.1007/bf01968942. [PMID: 11539555] - C A Lindsay, R Bawdon, R Quigley. Clearance of ticarcillin-clavulanic acid by continuous venovenous hemofiltration in three critically ill children, two with and one without concomitant extracorporeal membrane oxygenation.
Pharmacotherapy.
1996 May; 16(3):458-62. doi:
NULL. [PMID: 8726606] - M D Reed, T S Yamashita, J L Blumer. Pharmacokinetic-based ticarcillin/clavulanic acid dose recommendations for infants and children.
Journal of clinical pharmacology.
1995 Jul; 35(7):658-65. doi:
10.1002/j.1552-4604.1995.tb04105.x. [PMID: 7560245] - G La Follette, A L Jayewardene, A K Seneviratne, E T Lin, J G Gambertoglio. Determination of ticarcillin in human plasma and in urine by reversed-phase LC.
Journal of pharmaceutical and biomedical analysis.
1995 Feb; 13(2):159-64. doi:
10.1016/0731-7085(94)00137-q. [PMID: 7766723] - K Huh, J H Wilton, D E Nix, J J Schentag. Structures and biological activities of tobramycin-ticarcillin adducts.
Journal of pharmaceutical sciences.
1994 Jun; 83(6):763-7. doi:
10.1002/jps.2600830602. [PMID: 9120803] - T C Hardin, S C Butler, S Ross, J H Wakeford, J H Jorgensen. Comparison of ampicillin-sulbactam and ticarcillin-clavulanic acid in patients with chronic renal failure: effects of differential pharmacokinetics on serum bactericidal activity.
Pharmacotherapy.
1994 Mar; 14(2):147-52. doi:
NULL. [PMID: 8197032] - M Cazzola, M G Matera, G Santangelo, M Angrisani, A Loffreda, F de Prisco, G Paizis, F Rossi. Serum digoxin levels after concomitant ticarcillin and clavulanic acid administration.
Therapeutic drug monitoring.
1994 Feb; 16(1):46-8. doi:
10.1097/00007691-199402000-00007. [PMID: 8160254] - H Nakagawa, M Yamada, K Tokiyoshi, Y Miyawaki, T Kanayama. [Penetration of potassium clavulanate/ticarcillin sodium into cerebrospinal fluid in neurosurgical patients].
The Japanese journal of antibiotics.
1994 Jan; 47(1):93-101. doi:
NULL. [PMID: 8114276] - G W Roberts, R L Nation, A O Jarvinen, A J Martin. An in vivo assessment of the tobramycin/ticarcillin interaction in cystic fibrosis patients.
British journal of clinical pharmacology.
1993 Oct; 36(4):372-5. doi:
10.1111/j.1365-2125.1993.tb00380.x. [PMID: 12959319] - J P Wang, J D Unadkat, S M al-Habet, T A O'Sullivan, J Williams-Warren, A L Smith, B Ramsey. Disposition of drugs in cystic fibrosis. IV. Mechanisms for enhanced renal clearance of ticarcillin.
Clinical pharmacology and therapeutics.
1993 Sep; 54(3):293-302. doi:
10.1038/clpt.1993.150. [PMID: 8375124] - P Van der Auwera, V Duchateau, C Lambert, M Husson, M Kinzig, F Sörgel. Ex vivo pharmacodynamic study of piperacillin alone and in combination with tazobactam, compared with ticarcillin plus clavulanic acid.
Antimicrobial agents and chemotherapy.
1993 Sep; 37(9):1860-8. doi:
10.1128/aac.37.9.1860. [PMID: 8239597] - M G Matera, M Cazzola, E Lampa, G Santangelo, G Paizis, A Vinciguerra, F Rossi. Clinical pharmacokinetics of theophylline during co-treatment with ticarcillin plus clavulanic acid in patients suffering from acute exacerbation of chronic bronchitis.
Journal of chemotherapy (Florence, Italy).
1993 Aug; 5(4):233-6. doi:
10.1080/1120009x.1993.11739238. [PMID: 8229151] - A U Gerber, U Greter, C Segessenmann, S Kozak. The impact of the pre-treatment interval on antimicrobial efficacy in a biological model.
The Journal of antimicrobial chemotherapy.
1993 May; 31 Suppl D(?):29-39. doi:
10.1093/jac/31.suppl_d.29. [PMID: 8335522] - R Migliari, M Melis, G Palmieri, G Muscas, R Zuhair, M A Urru, M L Schivo, E Usai. [Treatment of urinary infections with ticarcillin and clavulanic acid (Clavucar) by the intramuscular route].
Minerva urologica e nefrologica = The Italian journal of urology and nephrology.
1992 Oct; 44(4):245-8. doi:
NULL. [PMID: 1299003] - A Kamoun, A Ben Hassen, C Fendri, S Ben Redjeb. [Pseudomonas aeruginosa and beta-lactam resistance phenotypes (Tunisia 1989-1990)].
Archives de l'Institut Pasteur de Tunis.
1992 Jul; 69(3-4):263-71. doi:
NULL. [PMID: 1341136] - R D Ing, J Saxe, S Hendrick, J Bailey, L N Diebel, S A Dulchavsky, W Brown. Antibiotic-primed fibrin gel improves outcome in contaminated splenic injury.
The Journal of trauma.
1992 Jul; 33(1):118-20. doi:
10.1097/00005373-199207000-00021. [PMID: 1635095] - K Adams, L Couch, G Cierny, J Calhoun, J T Mader. In vitro and in vivo evaluation of antibiotic diffusion from antibiotic-impregnated polymethylmethacrylate beads.
Clinical orthopaedics and related research.
1992 May; ?(278):244-52. doi:
10.1097/00003086-199205000-00037. [PMID: 1563160] - E J Catherall, V Gillon, S Hurn, R Irwin, L Mizen. Efficacy of ticarcillin-clavulanic acid for treatment of experimental Staphylococcus aureus endocarditis in rats.
Antimicrobial agents and chemotherapy.
1992 Feb; 36(2):458-62. doi:
10.1128/aac.36.2.458. [PMID: 1605610] - T Shimizu, S Souma, N Nagakura, T Masuzawa, Y Iwamoto, Y Yanagihara. Epitope analysis of aztreonam by antiaztreonam monoclonal antibodies and possible consequences in beta-lactams hypersensitivity.
International archives of allergy and immunology.
1992; 98(4):392-7. doi:
10.1159/000236216. [PMID: 1384868] - J O Errecalde, C E Lanusse, O N Mestorino, M F Landoni, A L Soraci. Pharmacokinetics of ticarcillin and ticarcillin-probenecid in sheep.
Zentralblatt fur Veterinarmedizin. Reihe A.
1991 May; 38(4):255-60. doi:
10.1111/j.1439-0442.1991.tb01010.x. [PMID: 1907783] - R B Moss, E McClelland, R R Williams, B C Hilman, T Rubio, N F Adkinson. Evaluation of the immunologic cross-reactivity of aztreonam in patients with cystic fibrosis who are allergic to penicillin and/or cephalosporin antibiotics.
Reviews of infectious diseases.
1991 May; 13 Suppl 7(?):S598-607. doi:
10.1093/clinids/13.supplement_7.s598. [PMID: 2068466] - A S Beale, J Gisby. Comparative efficacies of ticarcillin, ticarcillin/clavulanic acid, piperacillin and cefoxitin against polymicrobial infections in mice caused by Escherichia coli and Bacteroides fragilis.
Infection.
1991 Mar; 19(2):101-5. doi:
10.1007/bf01645577. [PMID: 2050417]