Cannabinol (BioDeep_00000001922)
Secondary id: BioDeep_00000408305
human metabolite PANOMIX_OTCML-2023 blood metabolite
代谢物信息卡片
化学式: C21H26O2 (310.1932696)
中文名称: 大麻酚
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 2.29%
分子结构信息
SMILES: CCCCCC1=CC(=C2C(=C1)OC(C3=C2C=C(C=C3)C)(C)C)O
InChI: InChI=1S/C21H26O2/c1-5-6-7-8-15-12-18(22)20-16-11-14(2)9-10-17(16)21(3,4)23-19(20)13-15/h9-13,22H,5-8H2,1-4H3
描述信息
C308 - Immunotherapeutic Agent > C574 - Immunosuppressant
同义名列表
数据库引用编号
17 个数据库交叉引用编号
- ChEBI: CHEBI:3360
- KEGG: C07580
- PubChem: 2543
- HMDB: HMDB0249590
- Metlin: METLIN41033
- DrugBank: DB14737
- ChEMBL: CHEMBL74415
- Wikipedia: Cannabinol
- MeSH: Cannabinol
- KNApSAcK: C00002675
- chemspider: 2447
- CAS: 521-35-7
- PMhub: MS000001452
- PubChem: 9782
- LipidMAPS: LMPK13120002
- 3DMET: B02128
- NIKKAJI: J6.613C
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
3 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Ning Wang, Boyu Liu, Donghua Wang, Kaiwen Xing, Wen Wang, Tong Wang, Dianyu Yu. Oil-in-water and oleogel-in-water emulsion encapsulate with hemp seed oil containing Δ9-tetrahydrocannabinol and cannabinol: Stability, degradation and in vitro simulation characteristics.
Food chemistry.
2024 Jun; 444(?):138633. doi:
10.1016/j.foodchem.2024.138633
. [PMID: 38330607] - Jenny L Wiley, Julie A Marusich, Bruce E Blough, Ojas Namjoshi, Marcus Brackeen, Luli R Akinfiresoye, Teneille D Walker, Cassandra Prioleau, Daniel G Barrus, Thomas F Gamage. Evaluation of cannabimimetic effects of selected minor cannabinoids and Terpenoids in mice.
Progress in neuro-psychopharmacology & biological psychiatry.
2024 Jun; 132(?):110984. doi:
10.1016/j.pnpbp.2024.110984
. [PMID: 38417478] - Oleh Durydivka, Petr Palivec, Matej Gazdarica, Ken Mackie, Jaroslav Blahos, Martin Kuchar. Hexahydrocannabinol (HHC) and Δ9-tetrahydrocannabinol (Δ9-THC) driven activation of cannabinoid receptor 1 results in biased intracellular signaling.
Scientific reports.
2024 04; 14(1):9181. doi:
10.1038/s41598-024-58845-7
. [PMID: 38649680] - Dylan T Marsh, Ayato Sugiyama, Yuta Imai, Ryuji Kato, Scott D Smid. The structurally diverse phytocannabinoids cannabichromene, cannabigerol and cannabinol significantly inhibit amyloid β-evoked neurotoxicity and changes in cell morphology in PC12 cells.
Basic & clinical pharmacology & toxicology.
2023 Sep; ?(?):. doi:
10.1111/bcpt.13943
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Journal of chromatography. A.
2023 Aug; 1705(?):464191. doi:
10.1016/j.chroma.2023.464191
. [PMID: 37454455] - Fresia Melina Silva Sofrás, Rosario Alonso, Daiana Sabrina Retta, Paola Di Leo Lira, Martin Federico Desimone, Catalina María van Baren. Development and Validation of a Simple, Fast, and Accessible HPLC-UV Method for Cannabinoids Determination in Cannabis sativa L. Extracts and Medicinal Oils.
Current pharmaceutical design.
2023 Aug; ?(?):. doi:
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Se pu = Chinese journal of chromatography.
2023 May; 41(5):426-433. doi:
10.3724/sp.j.1123.2022.08010
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2023 Mar; 1218(?):123629. doi:
10.1016/j.jchromb.2023.123629
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Frontiers in immunology.
2023; 14(?):1240800. doi:
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Protoplasma.
2023 Jan; 260(1):159-170. doi:
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Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
2023; 143(4):411-418. doi:
10.1248/yakushi.22-00198
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Analytical chemistry.
2022 Oct; 94(40):13710-13718. doi:
10.1021/acs.analchem.2c01627
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Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.
2022 Oct; 39(10):1705-1717. doi:
10.1080/19440049.2022.2107711
. [PMID: 35939416] - Maíra Ribeiro de Souza, Mariana Koetz, Renata Pereira Limberger, Amélia Teresinha Henriques. DoE-assisted development and validation of a stability-indicating HPLC-DAD method for simultaneous determination of five cannabinoids in Cannabis sativa L. based on analytical quality by design (AQbD) concept.
Phytochemical analysis : PCA.
2022 Oct; 33(7):999-1017. doi:
10.1002/pca.3154
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Cannabis and cannabinoid research.
2022 08; 7(4):537-547. doi:
10.1089/can.2021.0004
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Drug testing and analysis.
2022 Jul; 14(7):1223-1233. doi:
10.1002/dta.3241
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Forensic science international.
2022 Jun; 335(?):111309. doi:
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Journal of chromatography. A.
2022 May; 1671(?):463020. doi:
10.1016/j.chroma.2022.463020
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Molecules (Basel, Switzerland).
2022 May; 27(9):. doi:
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Molecules (Basel, Switzerland).
2022 Apr; 27(9):. doi:
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Drug metabolism and disposition: the biological fate of chemicals.
2021 12; 49(12):1070-1080. doi:
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Drug metabolism and disposition: the biological fate of chemicals.
2021 12; 49(12):1081-1089. doi:
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Journal of analytical toxicology.
2021 Sep; 45(8):807-812. doi:
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Journal of natural products.
2021 01; 84(1):142-160. doi:
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Journal of analytical toxicology.
2020 Oct; 44(7):651-660. doi:
10.1093/jat/bkaa046
. [PMID: 32369162] - Ieremias Chousidis, Theodoros Chatzimitakos, Dimitrios Leonardos, Michaela D Filiou, Constantine D Stalikas, Ioannis D Leonardos. Cannabinol in the spotlight: Toxicometabolomic study and behavioral analysis of zebrafish embryos exposed to the unknown cannabinoid.
Chemosphere.
2020 Aug; 252(?):126417. doi:
10.1016/j.chemosphere.2020.126417
. [PMID: 32200177] - Anubhav Pratap Singh, Farahnaz Fathordoobady, Yigong Guo, Anika Singh, David D Kitts. Antioxidants help favorably regulate the kinetics of lipid peroxidation, polyunsaturated fatty acids degradation and acidic cannabinoids decarboxylation in hempseed oil.
Scientific reports.
2020 06; 10(1):10567. doi:
10.1038/s41598-020-67267-0
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The Journal of pharmacology and experimental therapeutics.
2020 06; 373(3):416-428. doi:
10.1124/jpet.119.263319
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The journal of applied laboratory medicine.
2020 05; 5(3):569-574. doi:
10.1093/jalm/jfaa020
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Analytical and bioanalytical chemistry.
2020 Apr; 412(11):2633-2644. doi:
10.1007/s00216-020-02492-0
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Molecules (Basel, Switzerland).
2020 Mar; 25(6):. doi:
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Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964
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Journal of analytical toxicology.
2019 Oct; 43(9):746-752. doi:
10.1093/jat/bkz072
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Forensic science international.
2019 Jun; 299(?):142-150. doi:
10.1016/j.forsciint.2019.03.046
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Drug metabolism and disposition: the biological fate of chemicals.
2019 05; 47(5):465-472. doi:
10.1124/dmd.118.086074
. [PMID: 30833288] - Yedukondalu Nalli, Mohd Saleem Dar, Nasima Bano, Javeed Ur Rasool, Aminur R Sarkar, Junaid Banday, Aadil Qadir Bhat, Basit Rafia, Ram A Vishwakarma, Mohd Jamal Dar, Asif Ali. Analyzing the role of cannabinoids as modulators of Wnt/β-catenin signaling pathway for their use in the management of neuropathic pain.
Bioorganic & medicinal chemistry letters.
2019 05; 29(9):1043-1046. doi:
10.1016/j.bmcl.2019.03.013
. [PMID: 30871771] - Christopher W Cunningham. Plant-Based Modulators of Endocannabinoid Signaling.
Journal of natural products.
2019 03; 82(3):636-646. doi:
10.1021/acs.jnatprod.8b00874
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Gaceta medica de Mexico.
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Clinical pharmacology and therapeutics.
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Molecules (Basel, Switzerland).
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Therapeutic drug monitoring.
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The Journal of pharmacology and experimental therapeutics.
2016 08; 358(2):334-41. doi:
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Forensic science international.
2014 May; 238(?):113-9. doi:
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2013 Mar; 41(3):568-74. doi:
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The Journal of pharmacology and experimental therapeutics.
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Forensic science international.
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Drug metabolism and pharmacokinetics.
2012; 27(3):294-300. doi:
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Clinical chemistry.
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"
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European journal of pharmacology.
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Journal of natural products.
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
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Planta medica.
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BMC clinical pharmacology.
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Journal of analytical toxicology.
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Toxicology.
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