1,2-Didecanoylglycerol (BioDeep_00001883255)
代谢物信息卡片
1,2-Didecanoylglycerol
化学式: C23H44O5 (400.3189)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCCCCC(=O)OCC(CO)OC(=O)CCCCCCCCC
InChI: InChI=1S/C23H44O5/c1-3-5-7-9-11-13-15-17-22(25)27-20-21(19-24)28-23(26)18-16-14-12-10-8-6-4-2/h21,24H,3-20H2,1-2H3
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:11152
- PubChem: 1321
- ChEMBL: CHEMBL1871790
- CAS: 82950-64-9
- CAS: 17863-69-3
- MetaboLights: MTBLC11152
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Adriano L Souza, Felippe J Pavinatto, Luciano Caseli, Diogo Volpati, Paulo B Miranda, Osvaldo N Oliveira. Chitosan does not inhibit enzymatic action of human pancreatic lipase in Langmuir monolayers of 1,2-didecanoyl-glycerol (DDG).
Colloids and surfaces. B, Biointerfaces.
2014 Nov; 123(?):870-7. doi:
10.1016/j.colsurfb.2014.10.040. [PMID: 25466463] - Anaïs Bénarouche, Vanessa Point, Frédéric Carrière, Jean-François Cavalier. Using the reversible inhibition of gastric lipase by Orlistat for investigating simultaneously lipase adsorption and substrate hydrolysis at the lipid-water interface.
Biochimie.
2014 Jun; 101(?):221-31. doi:
10.1016/j.biochi.2014.01.019. [PMID: 24508576] - Philip Shushkov, Stanislav Tzvetanov, Maria Velinova, Anela Ivanova, Alia Tadjer. Structural aspects of lipid monolayers: computer simulation analyses.
Langmuir : the ACS journal of surfaces and colloids.
2010 Jun; 26(11):8081-92. doi:
10.1021/la904734b. [PMID: 20337413] - Stanislav Tzvetanov, Philip Shushkov, Maria Velinova, Anela Ivanova, Alia Tadjer. Molecular dynamics study of the electric and dielectric properties of model DPPC and dicaprin insoluble monolayers: size effect.
Langmuir : the ACS journal of surfaces and colloids.
2010 Jun; 26(11):8093-105. doi:
10.1021/la9047352. [PMID: 20337416] - Ikram Jemel, Ahmed Fendri, Youssef Gargouri, Sofiane Bezzine. Kinetic properties of dromedary pancreatic lipase: a comparative study on emulsified and monomolecular substrate.
Colloids and surfaces. B, Biointerfaces.
2009 May; 70(2):238-42. doi:
10.1016/j.colsurfb.2008.12.035. [PMID: 19195852] - Angela Bourbon Freie, Francine Ferrato, Frédéric Carrière, Mark E Lowe. Val-407 and Ile-408 in the beta5'-loop of pancreatic lipase mediate lipase-colipase interactions in the presence of bile salt micelles.
The Journal of biological chemistry.
2006 Mar; 281(12):7793-800. doi:
10.1074/jbc.m512984200. [PMID: 16431912] - S Lombard, M E Helmy, G Piéroni. Lipolytic activity of ricin from Ricinus sanguineus and Ricinus communis on neutral lipids.
The Biochemical journal.
2001 Sep; 358(Pt 3):773-81. doi:
10.1042/0264-6021:3580773. [PMID: 11535138] - E M Raeder, P J Mansfield, V Hinkovska-Galcheva, L Kjeldsen, J A Shayman, L A Boxer. Sphingosine blocks human polymorphonuclear leukocyte phagocytosis through inhibition of mitogen-activated protein kinase activation.
Blood.
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The Journal of investigative dermatology.
1996 Apr; 106(4):647-54. doi:
10.1111/1523-1747.ep12345463. [PMID: 8617999] - M Aoubala, M Ivanova, I Douchet, A De Caro, R Verger. Interfacial binding of human gastric lipase to lipid monolayers, measured with an ELISA.
Biochemistry.
1995 Aug; 34(34):10786-93. doi:
10.1021/bi00034a011. [PMID: 7545008] - K J Mills, S H Reynolds, R C Smart. Diacylglycerol is an effector of the clonal expansion of cells containing activated Ha-ras genes.
Carcinogenesis.
1993 Dec; 14(12):2645-8. doi:
10.1093/carcin/14.12.2645. [PMID: 8269640] - S Ransac, Y Gargouri, H Moreau, R Verger. Inactivation of pancreatic and gastric lipases by tetrahydrolipstatin and alkyl-dithio-5-(2-nitrobenzoic acid). A kinetic study with 1,2-didecanoyl-sn-glycerol monolayers.
European journal of biochemistry.
1991 Dec; 202(2):395-400. doi:
10.1111/j.1432-1033.1991.tb16387.x. [PMID: 1761041] - C Dahlgren, P Follin. Degranulation in human neutrophils primes the cells for subsequent responsiveness to the chemoattractant N-formylmethionylleucylphenylalanine but does not increase the sensitivity of the NADPH-oxidase to an intracellular calcium rise.
Biochimica et biophysica acta.
1990 Apr; 1052(1):42-6. doi:
10.1016/0167-4889(90)90055-i. [PMID: 2157502] - R C Smart, K J Mills, L A Hansen, A H Conney. Synthetic lipid second messenger sn-1,2-didecanoylglycerol: a complete tumor promoter in mouse skin.
Cancer research.
1989 Aug; 49(16):4455-8. doi:
. [PMID: 2743335] - Y Gargouri, G Pieroni, F Ferrato, R Verger. Human gastric lipase. A kinetic study with dicaprin monolayers.
European journal of biochemistry.
1987 Nov; 169(1):125-9. doi:
10.1111/j.1432-1033.1987.tb13588.x. [PMID: 3678230] - Y Gargouri, G Pieroni, C Rivière, A Sugihara, L Sarda, R Verger. Inhibition of lipases by proteins. A kinetic study with dicaprin monolayers.
The Journal of biological chemistry.
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