N-Methylephedrine (BioDeep_00001874472)

   

natural product


代谢物信息卡片


N-Methylephedrine

化学式: C11H17NO (179.1310072)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C(C1=CC=CC=C1)O)N(C)C
InChI: InChI=1S/C11H17NO/c1-9(12(2)3)11(13)10-7-5-4-6-8-10/h4-9,11,13H,1-3H3

描述信息

同义名列表

1 个代谢物同义名

N-Methylephedrine



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

21 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Hsin-Yi Hung, Shih-Min Lin, Chia-Ying Li, Sio-Hong Lam, Yu-Yi Chan, Meei-Jen Liou, Po-Chuen Shieh, Fu-An Chen, Ping-Chung Kuo, Tian-Shung Wu. A Rapid and Feasible 1H-NMR Quantification Method of Ephedrine Alkaloids in Ephedra Herbal Preparations. Molecules (Basel, Switzerland). 2021 Mar; 26(6):. doi: 10.3390/molecules26061599. [PMID: 33805790]
  • Nayoung Yun, Hye Jin Kim, Sang Cheol Park, Geonha Park, Min Kyung Kim, Young Hae Choi, Young Pyo Jang. Localization of Major Ephedra Alkaloids in Whole Aerial Parts of Ephedrae Herba Using Direct Analysis in Real Time-Time of Flight-Mass Spectrometry. Molecules (Basel, Switzerland). 2021 Jan; 26(3):. doi: 10.3390/molecules26030580. [PMID: 33499348]
  • Pengcheng Huang, Yinghong Tang, Chang Li, Huifen Zhou, Li Yu, Haitong Wan, Yu He. Correlation study between the pharmacokinetics of seven main active ingredients of Mahuang decoction and its pharmacodynamics in asthmatic rats. Journal of pharmaceutical and biomedical analysis. 2020 May; 183(?):113144. doi: 10.1016/j.jpba.2020.113144. [PMID: 32070931]
  • Albert Pérez-Alcaraz, Francesc Borrull, Carme Aguilar, Marta Calull. Enantioselective determination of cathinones in urine by high pressure in-line SPE-CE. Electrophoresis. 2019 07; 40(14):1762-1770. doi: 10.1002/elps.201900072. [PMID: 31093983]
  • Takashi Matsumoto, Hirotaka Kushida, Shoko Matsushita, Yoshiyuki Oyama, Takafumi Suda, Junko Watanabe, Yoshio Kase, Mitsutoshi Setou. Distribution Analysis via Mass Spectrometry Imaging of Ephedrine in the Lungs of Rats Orally Administered the Japanese Kampo Medicine Maoto. Scientific reports. 2017 03; 7(?):44098. doi: 10.1038/srep44098. [PMID: 28272490]
  • Eun Sook Jeong, Ki Hun Kim, Eunju Cha, Oh-Seung Kwon, Sangwon Cha, Jaeick Lee. Direct and rapid quantitation of ephedrines in human urine by paper spray ionization/high resolution mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2016 Aug; 1028(?):237-241. doi: 10.1016/j.jchromb.2016.06.040. [PMID: 27393909]
  • Asami Kojima, Yasunori Nishitani, Mitsuhiko Sato, Shinji Kageyama, Michiko Dohi, Masato Okano. Comparison of urine analysis and dried blood spot analysis for the detection of ephedrine and methylephedrine in doping control. Drug testing and analysis. 2016 Feb; 8(2):189-98. doi: 10.1002/dta.1803. [PMID: 25869885]
  • Tianhua Yan, Qiang Fu, Jing Wang, Shiping Ma. UPLC-MS/MS determination of ephedrine, methylephedrine, amygdalin and glycyrrhizic acid in Beagle plasma and its application to a pharmacokinetic study after oral administration of Ma Huang Tang. Drug testing and analysis. 2015 Feb; 7(2):158-63. doi: 10.1002/dta.1635. [PMID: 24824649]
  • Shuai Song, Qingfa Tang, Huiling Huo, Hancheng Li, Xuefeng Xing, Jiabo Luo. Simultaneous quantification and pharmacokinetics of alkaloids in Herba Ephedrae-Radix Aconiti Lateralis extracts. Journal of analytical toxicology. 2015 Jan; 39(1):58-68. doi: 10.1093/jat/bku113. [PMID: 25324527]
  • Jing Jia, Lili Xu, Shuai Wang, Licheng Wang, Xia Liu. Sol-gel approach for fabrication of coated anodized titanium wire for solid-phase microextraction: highly efficient adsorbents for enrichment of trace polar analytes. Analytical and bioanalytical chemistry. 2014 May; 406(13):3209-17. doi: 10.1007/s00216-014-7727-6. [PMID: 24682230]
  • Lin Zhang, Fucheng Zhang, Zhaohong Wang, Ye Jiang, Meng Xu, Hong Li. [Simultaneous determination of ephedrine and N-methylephedrine in urine by solid phase extraction-ultra performance liquid chromatography-electrospray ionization tandem mass spectrometry]. Se pu = Chinese journal of chromatography. 2013 Sep; 31(9):898-902. doi: 10.3724/sp.j.1123.2013.02028. [PMID: 24392629]
  • Li-ping Yu, Xiao-ke Wang, Jia-bo Luo. [Determination of ephedrine hydrochloride, pseudoephedrine hydrochloride and methylephedrine hydrochloride in maxingshigan decoction by CE]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2011 Apr; 34(4):620-3. doi: ". [PMID: 21809550]
  • Joaudimir Castro, M V Balarama Krishna, R Kenneth Marcus. Liquid chromatography-particle beam electron ionization mass spectrometry method for analysis of botanical extracts: evaluation of ephedrine alkaloids in standard reference materials. Journal of AOAC International. 2010 Nov; 93(6):1788-97. doi: . [PMID: 21313804]
  • Lihui Zheng, Lan Zhang, Ping Tong, Xinyu Zheng, Yuwu Chi, Guonan Chen. Highly sensitive transient isotachophoresis sample stacking coupling with capillary electrophoresis-amperometric detection for analysis of doping substances. Talanta. 2010 Jun; 81(4-5):1288-94. doi: 10.1016/j.talanta.2010.02.023. [PMID: 20441897]
  • Raz Krizevski, Einat Bar, Or Shalit, Yaron Sitrit, Shimon Ben-Shabat, Efraim Lewinsohn. Composition and stereochemistry of ephedrine alkaloids accumulation in Ephedra sinica Stapf. Phytochemistry. 2010 Jun; 71(8-9):895-903. doi: 10.1016/j.phytochem.2010.03.019. [PMID: 20417943]
  • Yan-Ming Liu, Wei Tian, Yu-Xiu Jia, Hai-Yan Yue. Simultaneous determination of methylephedrine and pseudoephedrine in human urine by CE with electrochemiluminescence detection and its application to pharmacokeinetics. Biomedical chromatography : BMC. 2009 Nov; 23(11):1138-44. doi: 10.1002/bmc.1235. [PMID: 19492345]
  • Sabina Strano-Rossi, Daniele Leone, Xavier de la Torre, Francesco Botrè. The relevance of the urinary concentration of ephedrines in anti-doping analysis: determination of pseudoephedrine, cathine, and ephedrine after administration of over-the-counter medicaments. Therapeutic drug monitoring. 2009 Aug; 31(4):520-6. doi: 10.1097/ftd.0b013e3181ac6006. [PMID: 19571776]
  • Yan-Ming Liu, Wei Tian, Yu-Xiu Jia, Hai-Yan Yue. The use of CE ECL with ionic liquid for the determination of drug alkaloids and applications in human urine. Electrophoresis. 2009 Apr; 30(8):1406-11. doi: 10.1002/elps.200800561. [PMID: 19294691]
  • Mario Thevis, Gerd Sigmund, Andreas Thomas, Vassilios Gougoulidis, Grigory Rodchenkov, Wilhelm Schänzer. Doping control analysis of metamfepramone and two major metabolites using liquid chromatography-tandem mass spectrometry. European journal of mass spectrometry (Chichester, England). 2009; 15(4):507-15. doi: 10.1255/ejms.1010. [PMID: 19661559]
  • Wei Zhao, An-Jun Deng, Guan-Hua Du, Jin-Lan Zhang, Zhi-Hong Li, Hai-Lin Qin. Chemical constituents of the stems of Ephedra sinica. Journal of Asian natural products research. 2009; 11(2):168-71. doi: 10.1080/10286020802573552. [PMID: 19219730]
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  • Min Wang, Philip J Marriott, Wing-Hong Chan, Albert W M Lee, Carmen W Huie. Enantiomeric separation and quantification of ephedrine-type alkaloids in herbal materials by comprehensive two-dimensional gas chromatography. Journal of chromatography. A. 2006 Apr; 1112(1-2):361-8. doi: 10.1016/j.chroma.2005.12.043. [PMID: 16387317]
  • Ying Lung Tseng, Min-Hua Shieh, Fan-Hsin Kuo. Metabolites of ephedrines in human urine after administration of a single therapeutic dose. Forensic science international. 2006 Mar; 157(2-3):149-55. doi: 10.1016/j.forsciint.2005.04.008. [PMID: 15885945]
  • Hafid Belhadj-Tahar, Nouredine Sadeg. Methcathinone: a new postindustrial drug. Forensic science international. 2005 Oct; 153(1):99-101. doi: 10.1016/j.forsciint.2005.04.023. [PMID: 15919169]
  • Li-Bin Liu, Zhi-Xia Zheng, Jin-Ming Lin. Application of dimethyl-beta-cyclodextrin as a chiral selector in capillary electrophoresis for enantiomer separation of ephedrine and related compounds in some drugs. Biomedical chromatography : BMC. 2005 Jul; 19(6):447-53. doi: 10.1002/bmc.504. [PMID: 16037931]
  • Lin Zhu, Xiaoyan Chen, Yifan Zhang, Hualing Yu, Dafang Zhong. Simultaneous determination of methylephedrine and noscapine in human plasma by liquid chromatography-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2005 Jun; 820(2):175-82. doi: 10.1016/j.jchromb.2005.03.010. [PMID: 15899371]
  • Kuei Hui Chan, Ryh-Nan Pan, Mei-Chich Hsu. Simultaneous quantification of six ephedrines in a Mahwang preparation and in urine by high-performance liquid chromatography. Biomedical chromatography : BMC. 2005 Jun; 19(5):337-42. doi: 10.1002/bmc.452. [PMID: 15931652]
  • William A Trujillo, Wendy R Sorenson. Determination of ephedrine alkaloids in human urine and plasma by liquid chromatography/tandem mass spectrometry: collaborative study. Journal of AOAC International. 2003 Jul; 86(4):643-56. doi: . [PMID: 14509420]
  • R Herráez-Hernández, P Campíns-Falcó. Derivatization of tertiary amphetamines with 9-fluorenylmethyl chloroformate for liquid chromatography: determination of N-methylephedrine. The Analyst. 2000 Jun; 125(6):1071-6. doi: 10.1039/b002138p. [PMID: 10932852]
  • N Okamura, H Miki, T Harada, S Yamashita, Y Masaoka, Y Nakamoto, M Tsuguma, H Yoshitomi, A Yagi. Simultaneous determination of ephedrine, pseudoephedrine, norephedrine and methylephedrine in Kampo medicines by high-performance liquid chromatography. Journal of pharmaceutical and biomedical analysis. 1999 Jun; 20(1-2):363-72. doi: 10.1016/s0731-7085(99)00065-5. [PMID: 10704044]
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