TRIPHENYLETHYLENE (BioDeep_00001874217)
Main id: BioDeep_00000009714
Volatile Flavor Compounds
代谢物信息卡片
TRIPHENYLETHYLENE
化学式: C20H16 (256.1251936)
中文名称: 三苯乙烯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C(C=C1)C=C(C2=CC=CC=C2)C3=CC=CC=C3
InChI: InChI=1S/C20H16/c1-4-10-17(11-5-1)16-20(18-12-6-2-7-13-18)19-14-8-3-9-15-19/h1-16H
描述信息
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D004965 - Estrogen Antagonists
同义名列表
2 个代谢物同义名
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:35034
- KEGG: C14134
- PubChem: 6025
- ChEMBL: CHEMBL3115201
- CAS: 58-72-0
- PubChem: 7846948
- NIKKAJI: J1.389G
- KNApSAcK: 35034
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Sudesh Rani, Vijay Luxami, Kamaldeep Paul. Synthesis of Triphenylethylene-Naphthalimide Conjugates as topoisomerase-IIα inhibitor and HSA binder.
ChemMedChem.
2021 06; 16(11):1821-1831. doi:
10.1002/cmdc.202100034. [PMID: 33725393] - Samy A F Morad, Su-Fern Tan, David J Feith, Mark Kester, David F Claxton, Thomas P Loughran, Brian M Barth, Todd E Fox, Myles C Cabot. Modification of sphingolipid metabolism by tamoxifen and N-desmethyltamoxifen in acute myelogenous leukemia--Impact on enzyme activity and response to cytotoxics.
Biochimica et biophysica acta.
2015 Jul; 1851(7):919-28. doi:
10.1016/j.bbalip.2015.03.001. [PMID: 25769964] - Huixiao Hong, William S Branham, Hui Wen Ng, Carrie L Moland, Stacey L Dial, Hong Fang, Roger Perkins, Daniel Sheehan, Weida Tong. Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and α-fetoprotein.
Toxicological sciences : an official journal of the Society of Toxicology.
2015 Feb; 143(2):333-48. doi:
10.1093/toxsci/kfu231. [PMID: 25349334] - Diana C Rueda, Angela Schöffmann, Maria De Mieri, Melanie Raith, Evelyn A Jähne, Steffen Hering, Matthias Hamburger. Identification of dihydrostilbenes in Pholidota chinensis as a new scaffold for GABAA receptor modulators.
Bioorganic & medicinal chemistry.
2014 Feb; 22(4):1276-84. doi:
10.1016/j.bmc.2014.01.008. [PMID: 24462176] - Luigi Gennari, Daniela Merlotti, Konstantinos Stolakis, Ranuccio Nuti. Pharmacokinetic evaluation of toremifene and its clinical implications for the treatment of osteoporosis.
Expert opinion on drug metabolism & toxicology.
2012 Apr; 8(4):505-13. doi:
10.1517/17425255.2012.665873. [PMID: 22356442] - Chinenye J Ugwah-Oguejiofor, Shaibu O Bello, Raymond U Okolo, Emmanuel U Etuk, Michael O Ugwah, Vincent U Igbokwe. Ficus platyphylla promotes fertility in female Rattus norvegicus Wistar strain: a preliminary study.
Reproductive biology and endocrinology : RB&E.
2011 Nov; 9(?):145. doi:
10.1186/1477-7827-9-145. [PMID: 22046966] - Luigi Gennari, Daniela Merlotti, Vincenzo De Paola, Giuseppe Martini, Ranuccio Nuti. Bazedoxifene for the prevention of postmenopausal osteoporosis.
Therapeutics and clinical risk management.
2008 Dec; 4(6):1229-42. doi:
10.2147/tcrm.s3476. [PMID: 19337430] - Yu-Bing Zhu, Qian Zhang, Jian-Jun Zou, Cui-Xia Yu, Da-Wei Xiao. Optimizing high-performance liquid chromatography method with fluorescence detection for quantification of tamoxifen and two metabolites in human plasma: application to a clinical study.
Journal of pharmaceutical and biomedical analysis.
2008 Jan; 46(2):349-55. doi:
10.1016/j.jpba.2007.10.012. [PMID: 18037598] - Monica Mazzarino, Ilaria Fiacco, Xavier de la Torre, Francesco Botrè. A mass spectrometric approach for the study of the metabolism of clomiphene, tamoxifen and toremifene by liquid chromatography time-of-flight spectroscopy.
European journal of mass spectrometry (Chichester, England).
2008; 14(3):171-80. doi:
10.1255/ejms.921. [PMID: 18708697] - Noel N Kim, Miljan Stankovic, Abdullah Armagan, Tulay T Cushman, Irwin Goldstein, Abdulmaged M Traish. Effects of tamoxifen on vaginal blood flow and epithelial morphology in the rat.
BMC women's health.
2006 Sep; 6(?):14. doi:
10.1186/1472-6874-6-14. [PMID: 16970814] - Jorge Marrero-Alonso, Benito García Marrero, Tomás Gómez, Mario Díaz. Functional inhibition of intestinal and uterine muscles by non-permeant triphenylethylene derivatives.
European journal of pharmacology.
2006 Feb; 532(1-2):115-27. doi:
10.1016/j.ejphar.2005.11.031. [PMID: 16466652] - Hong Fang, Weida Tong, William S Branham, Carrie L Moland, Stacy L Dial, Huixiao Hong, Qian Xie, Roger Perkins, William Owens, Daniel M Sheehan. Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor.
Chemical research in toxicology.
2003 Oct; 16(10):1338-58. doi:
10.1021/tx030011g. [PMID: 14565775] - Tamás Nagykálnai. [Selective estrogen receptor modulators (SERMs) in the practice].
Magyar onkologia.
2002; 46(2):165-75. doi:
huon.2002.46.2.0165. [PMID: 12202896] - G Grenier, G Bérubé, C Gicquaud. Effects of new triphenylethylene platinum(II) complexes on the interaction with phosphatidylcholine liposomes.
Chemical & pharmaceutical bulletin.
1998 Sep; 46(9):1480-3. doi:
10.1248/cpb.46.1480. [PMID: 9775443] - H Wiseman, C Smith, H R Arnstein, B Halliwell, M Cannon. The antioxidant action of ketoconazole and related azoles: comparison with tamoxifen and cholesterol.
Chemico-biological interactions.
1991; 79(2):229-43. doi:
10.1016/0009-2797(91)90085-l. [PMID: 1884432] - Y M Huet-Hudson, S K Dey. Differential effects of ovarian steroids and triphenylethylene compounds on macromolecular uptake and thymidine incorporation in the mouse uterus.
Journal of steroid biochemistry.
1990 Jan; 35(1):23-7. doi:
10.1016/0022-4731(90)90140-n. [PMID: 2407900] - C A O'Brian, N E Ward, B W Anderson. Role of specific interactions between protein kinase C and triphenylethylenes in inhibition of the enzyme.
Journal of the National Cancer Institute.
1988 Dec; 80(20):1628-33. doi:
10.1093/jnci/80.20.1628. [PMID: 3264029] - A Gulino, A Vacca, A Modesti, I Screpanti, A Farina, L Frati. Subcellular and extracellular localization of specific binding sites for triphenylethylene antiestrogens in human breast cancer.
Biochemical pharmacology.
1986 Nov; 35(21):3863-70. doi:
10.1016/0006-2952(86)90677-5. [PMID: 3778510] - C A O'Brian, R M Liskamp, D H Solomon, I B Weinstein. Triphenylethylenes: a new class of protein kinase C inhibitors.
Journal of the National Cancer Institute.
1986 Jun; 76(6):1243-6. doi:
. [PMID: 3458960] - C Sonnenschein, J T Papendorp, A M Soto. Estrogenic effect of tamoxifen and its derivatives on the proliferation of MCF7 human breast tumor cells.
Life sciences.
1985 Jul; 37(4):387-94. doi:
10.1016/0024-3205(85)90510-7. [PMID: 4010480] - R C Winneker, S C Guthrie, J H Clark. Characterization of a triphenylethylene-antiestrogen-binding site on rat serum low density lipoprotein.
Endocrinology.
1983 May; 112(5):1823-7. doi:
10.1210/endo-112-5-1823. [PMID: 6832070]