EPN (BioDeep_00001873679)
Main id: BioDeep_00000009897
代谢物信息卡片
化学式: C14H14NO4PS (323.0381)
中文名称: 苯硫磷酯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCOP(=S)(C1=CC=CC=C1)OC2=CC=C(C=C2)[N+](=O)[O-]
InChI: InChI=1S/C14H14NO4PS/c1-2-18-20(21,14-6-4-3-5-7-14)19-13-10-8-12(9-11-13)15(16)17/h3-11H,2H2,1H3
描述信息
D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D002800 - Cholinesterase Inhibitors
D010575 - Pesticides > D007306 - Insecticides
D004791 - Enzyme Inhibitors
D016573 - Agrochemicals
同义名列表
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:34733
- KEGG: C14434
- PubChem: 16421
- ChEMBL: CHEMBL3184641
- MeSH: Phenylphosphonothioic Acid, 2-Ethyl 2-(4-Nitrophenyl) Ester
- CAS: 2104-64-5
- PubChem: 17395434
- NIKKAJI: J2.140G
- RefMet: EPN
- KNApSAcK: 34733
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Hiroyuki Kojima, Fumihiro Sata, Shinji Takeuchi, Tatsuya Sueyoshi, Tadanori Nagai. Comparative study of human and mouse pregnane X receptor agonistic activity in 200 pesticides using in vitro reporter gene assays.
Toxicology.
2011 Feb; 280(3):77-87. doi:
10.1016/j.tox.2010.11.008. [PMID: 21115097] - Tomomi Tanaka, Tomiyuki Hori, Takashi Asada, Kikuo Oikawa, Kuniaki Kawata. Simple one-step extraction and cleanup by pressurized liquid extraction for gas chromatographic-mass spectrometric determination of pesticides in green leafy vegetables.
Journal of chromatography. A.
2007 Dec; 1175(2):181-6. doi:
10.1016/j.chroma.2007.10.060. [PMID: 17996881] - Soon-Kil Cho, A M Abd El-Aty, Young-Seok Park, Jeong-Heui Choi, Sathya Khay, Cheol-Ah Kang, Byung-Jun Park, Sun-Ju Kim, Jae-Han Shim. A multiresidue method for the analysis of pesticide residues in polished rice (Oryza sativa L.) using accelerated solvent extraction and gas chromatography and confirmation by mass spectrometry.
Biomedical chromatography : BMC.
2007 Jun; 21(6):602-9. doi:
10.1002/bmc.792. [PMID: 17385804] - Yasuhiro Fujikawa, Tetsuo Satoh, Akiyoshi Suganuma, Satoshi Suzuki, Yasuko Niikura, Shinobu Yui, Yoshiro Yamaura. Extremely sensitive biomarker of acute organophosphorus insecticide exposure.
Human & experimental toxicology.
2005 Jun; 24(6):333-6. doi:
10.1191/0960327105ht532oa. [PMID: 16004201] - T Satoh, S Suzuki, N Kawai, T Nakamura, M Hosokawa. Toxicological significance in the cleavage of esterase-beta-glucuronidase complex in liver microsomes by organophosphorus compounds.
Chemico-biological interactions.
1999 May; 119-120(?):471-8. doi:
10.1016/s0009-2797(99)00060-5. [PMID: 10421485] - A K Chatterjee, U Kaveeshwar. Protective effect of a high protein diet against the toxicity of some organophosphorus compounds in albino rats.
Japanese journal of pharmacology.
1991 Oct; 57(2):147-52. doi:
10.1254/jjp.57.147. [PMID: 1812296] - D J Hoffman, L Sileo, H C Murray. Subchronic organophosphorus ester-induced delayed neurotoxicity in mallards.
Toxicology and applied pharmacology.
1984 Aug; 75(1):128-36. doi:
10.1016/0041-008x(84)90083-8. [PMID: 6205472] - D J Hoffman, L Sileo. Neurotoxic and teratogenic effects of an organophosphorus insecticide (phenyl phosphonothioic acid-O-ethyl-O-[4-nitrophenyl] ester) on mallard development.
Toxicology and applied pharmacology.
1984 Apr; 73(2):284-94. doi:
10.1016/0041-008x(84)90334-x. [PMID: 6710528] - M B Abou-Donia, B L Reichert, M A Ashry. The absorption, distribution, excretion, and metabolism of a single oral dose of O-ethyl O-4-nitrophenyl phenylphosphonothioate in hens.
Toxicology and applied pharmacology.
1983 Aug; 70(1):18-28. doi:
10.1016/0041-008x(83)90175-8. [PMID: 6612735] - M B Abou-Donia, K Sivarajah, S A Abou-Donia. Disposition, elimination and metabolism of O-ethyl O-4-nitrophenyl phenylphosphonothioate after subchronic dermal application in male cats.
Toxicology.
1983 Feb; 26(2):93-111. doi:
10.1016/0300-483x(83)90061-6. [PMID: 6857694] - M B Abou-Donia, D G Graham, H A Makkawy, K M Abdo. Effect of subchronic dermal application of O-ethyl O-4-nitrophenyl phenylphosphonothioate on producing delayed neurotoxicity in hens.
Neurotoxicology.
1983; 4(2):247-60. doi:
. [PMID: 6685263] - M B Abou-Donia, C G Kinnes, K M Abdo, T D Bjornsson. Physiological disposition and metabolism of O-ethyl-O-4-nitrophenyl phenylphosphonothioate in male cats following a single dermal administration.
Drug metabolism and disposition: the biological fate of chemicals.
1983 Jan; 11(1):31-6. doi:
. [PMID: 6132792] - E E Enan, A H El-Sebae, O H Enan, S El-Fiki. In-vivo interaction of some organophosphorus insecticides with different biochemical targets in white rats.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes.
1982; 17(5):549-70. doi:
10.1080/03601238209372341. [PMID: 6184393] - G P Carlson. Effect of trichlorophenols on xenobiotic metabolism in the rat.
Toxicology.
1978 Oct; 11(2):145-51. doi:
10.1016/s0300-483x(78)90939-3. [PMID: 102051] - T Sato, K Moroi. Comparative studies on the inhibition of liver amidases, aminopeptidase and serum cholinesterases by EPN.
Toxicology and applied pharmacology.
1973 Aug; 25(4):553-9. doi:
10.1016/0041-008x(73)90024-0. [PMID: 4741776]
